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Volumn 8, Issue 18, 1997, Pages 3035-3038

Enantioselective reduction of β-keto amides by the fungus Mortierella isabellina

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; HYDROXYACID;

EID: 0030884042     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(97)00378-9     Document Type: Article
Times cited : (30)

References (32)
  • 13
    • 0343943953 scopus 로고    scopus 로고
    • See reference cited in note 4
    • See reference cited in note 4.
  • 14
    • 0343072160 scopus 로고    scopus 로고
    • note
    • 1H-NMR analysis) after 110 hours of incubation.
  • 15
    • 0001677435 scopus 로고
    • Mortierella isabellina NRRL 1757 transforms, inter alia, acetophenone into (S)-1-phenylethanol with moderate ee (54%), and also chroman-4-one and thiochroman-4-one into their respective enantiopure (S)-alcohols. See: a) Holland, H. L.; Bergen, E. J.; Chenchaiah, P. C.; Khan, S. H.; Munoz, B.; Ninniss, R.; Richards, D. Can. J. Chem. 1987, 65, 502-507.
    • (1987) Can. J. Chem. , vol.65 , pp. 502-507
    • Holland, H.L.1    Bergen, E.J.2    Chenchaiah, P.C.3    Khan, S.H.4    Munoz, B.5    Ninniss, R.6    Richards, D.7
  • 17
    • 0343943951 scopus 로고    scopus 로고
    • note
    • Saturation of 1,4-dioxane with gaseous methylamine coming from heating a mixture of methylammonium chloride and solid sodium hydroxide; then, Candida antarctica lipase-catalysed aminolysis of ethyl 3-oxo-3-phenylpropanoate.
  • 18
    • 0342637927 scopus 로고    scopus 로고
    • note
    • Shorter growing times require too long reaction times.
  • 19
    • 0343072158 scopus 로고    scopus 로고
    • note
    • 2O:MeOH 4:1:0.1, and then AcOEt)] to afford the corresponding (S)-β-hydroxy amide 2.
  • 21
    • 0343508253 scopus 로고    scopus 로고
    • note
    • To our knowledge, (S)-2a and (S)-2d are previously unknown compounds; both products give satisfactory analytical and spectral data.
  • 24
    • 0343943949 scopus 로고    scopus 로고
    • note
    • iOH 95:5, 0.8 mL/min.).
  • 26
    • 0343508251 scopus 로고    scopus 로고
    • note
    • 3 as an external standard) for the diastereomeric MPTA-esters derived from: (S)-2e, -71.87; (±)-2e, -71.97 and -71.87; (S)-2f, -71.88; (±)-2f, -71.91 and -71.88.
  • 28
    • 0342637926 scopus 로고    scopus 로고
    • note
    • 3.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.