-
1
-
-
0026034792
-
Human catechol-O-methyltransferase: Cloning and expression of the membrane-associated form
-
Bertocci B., Miggiano V., Da Prada M., Dembic Z., Lahm H.-W., Malherbe P. Human catechol-O-methyltransferase: cloning and expression of the membrane-associated form. Proc. Natl. Acad. Sci. USA. 88:1991;1416-1420.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 1416-1420
-
-
Bertocci, B.1
Miggiano, V.2
Da Prada, M.3
Dembic, Z.4
Lahm, H.-W.5
Malherbe, P.6
-
2
-
-
0029975425
-
Evaluation of cathepsin D and G and EC 3.4.24.15 as candidate β-secretase proteases using peptide and amyloid precursor protein substrates
-
Brown A.M., Tummolo D.M., Spruyt M.A., Jacobsen J.S., Sonnenberg-Reines J. Evaluation of cathepsin D and G and EC 3.4.24.15 as candidate β-secretase proteases using peptide and amyloid precursor protein substrates. J. Neurochem. 66:1996;2436-2445.
-
(1996)
J. Neurochem.
, vol.66
, pp. 2436-2445
-
-
Brown, A.M.1
Tummolo, D.M.2
Spruyt, M.A.3
Jacobsen, J.S.4
Sonnenberg-Reines, J.5
-
3
-
-
0028947294
-
Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: Evidence for early up-regulation of the endosomal-lysosomal system
-
Cataldo A.M., Barnett J.L., Berman S.A., Li J., Quarless S., Bursztajn S., Lippa C., Nixon R.A. Gene expression and cellular content of cathepsin D in Alzheimer's disease brain: evidence for early up-regulation of the endosomal-lysosomal system. Neuron. 14:1995;671-680.
-
(1995)
Neuron
, vol.14
, pp. 671-680
-
-
Cataldo, A.M.1
Barnett, J.L.2
Berman, S.A.3
Li, J.4
Quarless, S.5
Bursztajn, S.6
Lippa, C.7
Nixon, R.A.8
-
4
-
-
0029379605
-
Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease
-
Checler F. Processing of the β-amyloid precursor protein and its regulation in Alzheimer's disease. J. Neurochem. 65:1995;1431-1444.
-
(1995)
J. Neurochem.
, vol.65
, pp. 1431-1444
-
-
Checler, F.1
-
5
-
-
0028924248
-
Generation of amyloid β protein from its precursor is sequence specific
-
Citron M., Teplow D.B., Selkoe D.J. Generation of amyloid β protein from its precursor is sequence specific. Neuron. 14:1995;661-670.
-
(1995)
Neuron
, vol.14
, pp. 661-670
-
-
Citron, M.1
Teplow, D.B.2
Selkoe, D.J.3
-
6
-
-
0029933172
-
Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain
-
Conn K.J., Pietropaolo M., Ju S.-T., Abraham C.R. Monoclonal antibodies against the human metalloprotease EC 3.4.24.15 label neurofibrillary tangles in Alzheimer's disease brain. J. Neurochem. 66:1996;2011-2018.
-
(1996)
J. Neurochem.
, vol.66
, pp. 2011-2018
-
-
Conn, K.J.1
Pietropaolo, M.2
Ju, S.-T.3
Abraham, C.R.4
-
7
-
-
0342318219
-
-
Amyloidin protease and uses thereof, US Patent 5,424,205 (1995)
-
Dovey, H.F., Seubert, P.A. and Sinha, S., Amyloidin protease and uses thereof, US Patent 5,424,205 (1995).
-
-
-
Dovey, H.F.1
Seubert, P.A.2
Sinha, S.3
-
8
-
-
0028168276
-
Processing of the pre-β-amyloid protein by cathepsin D is enhanced by a familial Alzheimer's disease mutation
-
Dreyer R.N., Bausch K.M., Fracasso P., Hammond L.J., Wunderlich D., Wirak D.O., Davis G., Brini C.M., Buckholz T.M., Koenig G., Kamarck M.E., Tamburini P.P. Processing of the pre-β-amyloid protein by cathepsin D is enhanced by a familial Alzheimer's disease mutation. Eur. J. Biochem. 224:1994;265-271.
-
(1994)
Eur. J. Biochem.
, vol.224
, pp. 265-271
-
-
Dreyer, R.N.1
Bausch, K.M.2
Fracasso, P.3
Hammond, L.J.4
Wunderlich, D.5
Wirak, D.O.6
Davis, G.7
Brini, C.M.8
Buckholz, T.M.9
Koenig, G.10
Kamarck, M.E.11
Tamburini, P.P.12
-
11
-
-
0028866435
-
The Swedish mutation causes early-onset AD by β-secretase cleavage within the secretory pathway
-
Haass C., Lemere C., Capell A., Citron M., Seubert P., Schenk D., Lannfelt L., Selkoe D. The Swedish mutation causes early-onset AD by β-secretase cleavage within the secretory pathway. Nature Med. 1:1995;1291-1295.
-
(1995)
Nature Med.
, vol.1
, pp. 1291-1295
-
-
Haass, C.1
Lemere, C.2
Capell, A.3
Citron, M.4
Seubert, P.5
Schenk, D.6
Lannfelt, L.7
Selkoe, D.8
-
12
-
-
0026646604
-
Amyloid β-peptide is produced by cultured cells during normal metabolism
-
Haass C., Schlossmacher M.G., Hung A.Y., Vigo-Pelfrey C., Mellon A., Ostasezwski B.L., Lieberburg I., Koo E.H., Schenk D., Teplow D.B., Selkoe D.J. Amyloid β-peptide is produced by cultured cells during normal metabolism. Nature. 359:1992;322-325.
-
(1992)
Nature
, vol.359
, pp. 322-325
-
-
Haass, C.1
Schlossmacher, M.G.2
Hung, A.Y.3
Vigo-Pelfrey, C.4
Mellon, A.5
Ostasezwski, B.L.6
Lieberburg, I.7
Koo, E.H.8
Schenk, D.9
Teplow, D.B.10
Selkoe, D.J.11
-
13
-
-
0023105114
-
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor
-
Kang J., Lemaire H.G., Unterbeck A., Salbaum J.M., Masters C.L., Grzeschik K.H., Multhaup G., Beyreuther K., Mueller-Hill B. The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor. Nature. 325:1987;733-736.
-
(1987)
Nature
, vol.325
, pp. 733-736
-
-
Kang, J.1
Lemaire, H.G.2
Unterbeck, A.3
Salbaum, J.M.4
Masters, C.L.5
Grzeschik, K.H.6
Multhaup, G.7
Beyreuther, K.8
Mueller-Hill, B.9
-
14
-
-
0026636925
-
Proteolytic processing sites producing the mature form of human cathepsin D
-
Kobayashi T., Honke K., Gasa S., Fujii T., Maguchi S., Miyazaki T., Makita A. Proteolytic processing sites producing the mature form of human cathepsin D. Int. J. Biochem. 24:1992;1487-1491.
-
(1992)
Int. J. Biochem.
, vol.24
, pp. 1487-1491
-
-
Kobayashi, T.1
Honke, K.2
Gasa, S.3
Fujii, T.4
Maguchi, S.5
Miyazaki, T.6
Makita, A.7
-
15
-
-
0029146046
-
Cathepsin D from Alzheimer's-diseased and normal brains
-
Kohnken R.E., Ladror U.S., Wang G.T., Holzman T.F., Miller B.E., Krafft G.A. Cathepsin D from Alzheimer's-diseased and normal brains. Exp. Neurol. 133:1995;105-112.
-
(1995)
Exp. Neurol.
, vol.133
, pp. 105-112
-
-
Kohnken, R.E.1
Ladror, U.S.2
Wang, G.T.3
Holzman, T.F.4
Miller, B.E.5
Krafft, G.A.6
-
16
-
-
0028277270
-
Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-β By cathepsin D
-
Ladror U.S., Snyder S.W., Wang G.T., Holzman T.F., Krafft G.A. Cleavage at the amino and carboxyl termini of Alzheimer's amyloid-β by cathepsin D. J. Biol. Chem. 269:1994;18422-18428.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18422-18428
-
-
Ladror, U.S.1
Snyder, S.W.2
Wang, G.T.3
Holzman, T.F.4
Krafft, G.A.5
-
17
-
-
0028336792
-
Molecular cloning and functional expression of human 3-hydroxyanthranilic acid dioxygenase
-
Malherbe P., Köhler C., Da Prada M., Lang G., Kiefer V., Schwarcz R., Lahm H.-W., Cesura A.M. Molecular cloning and functional expression of human 3-hydroxyanthranilic acid dioxygenase. J. Biol. Chem. 269:1994;13792-13797.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 13792-13797
-
-
Malherbe, P.1
Köhler, C.2
Da Prada, M.3
Lang, G.4
Kiefer, V.5
Schwarcz, R.6
Lahm, H.-W.7
Cesura, A.M.8
-
18
-
-
0016668570
-
Changes in proteolytic enzymes and proteins during maturation of the brain
-
Marks N., Stern F., Lajla A. Changes in proteolytic enzymes and proteins during maturation of the brain. Brain Res. 86:1975;307-322.
-
(1975)
Brain Res.
, vol.86
, pp. 307-322
-
-
Marks, N.1
Stern, F.2
Lajla, A.3
-
19
-
-
0026769423
-
Human brain peptidase activity with the specificity to generate the N-terminus of the Alzheimer β-amyloid protein from its precursor
-
McDermott J.R., Biggins J.A., Gibson A.M. Human brain peptidase activity with the specificity to generate the N-terminus of the Alzheimer β-amyloid protein from its precursor. Biochem. Biophys. Res. Commun. 185:1992;746-752.
-
(1992)
Biochem. Biophys. Res. Commun.
, vol.185
, pp. 746-752
-
-
McDermott, J.R.1
Biggins, J.A.2
Gibson, A.M.3
-
20
-
-
0029112811
-
Lysosomal processing of amyloid precursor protein to Aβ peptides: A distinct role for cathepsin S
-
Munger J.S., Haass C., Lemere C.A., Shi G.-P., Wong W.S.F., Teplow D.B., Selkoe D.J., Chapman H.A. Lysosomal processing of amyloid precursor protein to Aβ peptides: a distinct role for cathepsin S. Biochem. J. 311:1995;299-305.
-
(1995)
Biochem. J.
, vol.311
, pp. 299-305
-
-
Munger, J.S.1
Haass, C.2
Lemere, C.A.3
Shi, G.-P.4
Wong, W.S.F.5
Teplow, D.B.6
Selkoe, D.J.7
Chapman, H.A.8
-
21
-
-
0028040302
-
Identification of a metalloprotease from Alzheimer's disease brain able to degrade the β-amyloid precursor protein and generate amyloidogenic fragments
-
Papastoitsis G., Siman R., Scott R., Abraham C.R. Identification of a metalloprotease from Alzheimer's disease brain able to degrade the β-amyloid precursor protein and generate amyloidogenic fragments. Biochemistry. 33:1994;192-199.
-
(1994)
Biochemistry
, vol.33
, pp. 192-199
-
-
Papastoitsis, G.1
Siman, R.2
Scott, R.3
Abraham, C.R.4
-
22
-
-
0026674462
-
A calcium-stimulated serine protease from monkey brain degrades the β-amyloid precursor protein
-
Razzaboni B.L., Papastoitsis G., Koo E.H., Abraham C.R. A calcium-stimulated serine protease from monkey brain degrades the β-amyloid precursor protein. Brain Res. 589:1992;207-216.
-
(1992)
Brain Res.
, vol.589
, pp. 207-216
-
-
Razzaboni, B.L.1
Papastoitsis, G.2
Koo, E.H.3
Abraham, C.R.4
-
23
-
-
0029970783
-
Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D
-
Saftig P., Peters C., Von Figura K., Craessaerts K., Van Leuven F., De Strooper B. Amyloidogenic processing of human amyloid precursor protein in hippocampal neurons devoid of cathepsin D. J. Biol. Chem. 271:1996;27241-27244.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27241-27244
-
-
Saftig, P.1
Peters, C.2
Von Figura, K.3
Craessaerts, K.4
Van Leuven, F.5
De Strooper, B.6
-
24
-
-
0028236347
-
Purification and characterization of a novel metalloprotease from human brain with the ability to cleave substrates derived from the N-terminus of β-amyloid protein
-
Schönlein C., Löffler J., Huber G. Purification and characterization of a novel metalloprotease from human brain with the ability to cleave substrates derived from the N-terminus of β-amyloid protein. Biochem. Biophys. Res. Commun. 201:1994;45-53.
-
(1994)
Biochem. Biophys. Res. Commun.
, vol.201
, pp. 45-53
-
-
Schönlein, C.1
Löffler, J.2
Huber, G.3
-
25
-
-
0028812394
-
Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease
-
Schwagerl A.L., Mohan P.S., Cataldo A.M., Vonsattel J.P., Kowall N.W., Nixon R.A. Elevated levels of the endosomal-lysosomal proteinase cathepsin D in cerebrospinal fluid in Alzheimer disease. J. Neurochem. 64:1995;443-446.
-
(1995)
J. Neurochem.
, vol.64
, pp. 443-446
-
-
Schwagerl, A.L.1
Mohan, P.S.2
Cataldo, A.M.3
Vonsattel, J.P.4
Kowall, N.W.5
Nixon, R.A.6
-
26
-
-
0028267440
-
Normal and abnormal biology of the β-amyloid precursor protein
-
Selkoe D.J. Normal and abnormal biology of the β-amyloid precursor protein. Annu. Rev. Neurosci. 17:1994;489-517.
-
(1994)
Annu. Rev. Neurosci.
, vol.17
, pp. 489-517
-
-
Selkoe, D.J.1
-
27
-
-
0026646605
-
Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids
-
Seubert P., Vigo-Pelfrey C., Esch F., Lee M., Dovey H., Davis D., Sinha S., Schlossmacher M., Whaley J., Swindlehurst C., McCormack R., Wolfert R., Selkoe D., Lieberburg I., Schenk D. Isolation and quantification of soluble Alzheimer's β-peptide from biological fluids. Nature. 359:1992;325-327.
-
(1992)
Nature
, vol.359
, pp. 325-327
-
-
Seubert, P.1
Vigo-Pelfrey, C.2
Esch, F.3
Lee, M.4
Dovey, H.5
Davis, D.6
Sinha, S.7
Schlossmacher, M.8
Whaley, J.9
Swindlehurst, C.10
McCormack, R.11
Wolfert, R.12
Selkoe, D.13
Lieberburg, I.14
Schenk, D.15
-
28
-
-
0029163006
-
Cloning and functional expression of a metalloendopeptidase from human brain with the ability to cleave a β-APP substrate peptide
-
Thompson A., Huber G., Malherbe P. Cloning and functional expression of a metalloendopeptidase from human brain with the ability to cleave a β-APP substrate peptide. Biochem. Biophys. Res. Commun. 213:1995;66-73.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.213
, pp. 66-73
-
-
Thompson, A.1
Huber, G.2
Malherbe, P.3
-
29
-
-
0029896354
-
Mechanisms of neuronal degeneration in Alzheimer's disease
-
Yankner B.A. Mechanisms of neuronal degeneration in Alzheimer's disease. Neuron. 16:1996;921-932.
-
(1996)
Neuron
, vol.16
, pp. 921-932
-
-
Yankner, B.A.1
|