Mechanisms of loss of functional dendritic cells in HIV-1 infection

Journal of Leukocyte Biology

Volumn 62, Issue 1, 1997, Pages 78-81

  Knight, Stella C ^a   Elsley, William ^a   Wang, Hong ^a  

^a NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

Author keywords

Cytotoxic T lymphocytes; Maturation of dendritic cells

Indexed keywords

CD34 ANTIGEN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ARTICLE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; T LYMPHOCYTE SUBPOPULATION; VIRUS INFECTION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0030879155     PISSN: 07415400     EISSN: None     Source Type: Journal    
DOI: 10.1002/jlb.62.1.78     Document Type: Article

References (16)

1. Knight, S. C. (1996) Bone-marrow derived dendritic cells and the pathogenesis of AIDS. AIDS 10, 807-817.
2. Knight, S., Stagg, A. J. (1993) Antigen presenting cell types. Curr. Op. Immunol. 5, 374-382.
3. Zinkernagel, R. M. (1988) Virus-triggered AIDS: a T cell-mediated immunopathology? Immunol. Today 9, 370-371.
4. Borrow, P., Evans, C. F., Oldstone, M. B. A. (1995) Virus-induced immunosuppression: Immune system-mediated destruction of virus-infected dendritic cells results in generalized immune suppression. J. Virol. 69, 1059-1070.
5. Spira, A. J., Marx, P. A., Patterson, B. K., Mahoney, J., Koup, R. A., Wolinsky, S. M., Ho, D. D. (1996) Cellular targets of infection and route of viral dissemination after an intravaginal inoculation of simian immunodeficiency virus into rhesus macaques. J. Exp. Med. 183, 215-225.
6. Macatonia, S. E., Patterson, S., Knight, S. C. (1991) Primary proliferate and cytotoxic T cell responses to HIV induced in vitro by human dendritic cells. Immunology 74, 399-406.
7. Cameron, P. U., Lowe, M. G., Crowe, S. M., O'Doherty, U., Pope, M., Gezelter, S., Steinman, R. M. (1994) Susceptibility of dendritic cells to HIV-1 infection in vitro. J. Leukoc. Biol. 56, 257-265.
8. + T cells. Science 257, 383-386.
9. Pope, M., Betjes, M. G. H., Romani, N., Hirmand, H., Cameron, P. U., Hoffman, L., Gezelter, S., Schuler, G., Steinman, R. M. (1994) Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1 Cell 78, 389-398.
10. Autrun, B., Hadida, F., Haas, G. (1996) Evolution and plasticity of CTL responses against HIV. Curr. Op. Immunol. 8, 546-553.
11. Knight, S. C., Askonas, B. A., Macatonia, S. E. Dendritic cells as targets for cytotoxic T lymphocytes. Adv. Exp. Biol. Med., In press.
12. Macatonia, S. E., Lau, R., Patterson, S., Pinching, A. J., Knight, S. C. (1990) Dendritic cell infection, depletion and dysfunction in HIV infected individuals. Immunology 71, 38-45.
13. Macatonia, S. E., Patterson, S., Knight, S. C. (1989) Suppression of immune responses by dendritic cells infected with HIV. Immunology 67, 285-289.
14. Gabrilovich, D. I., Woods, G. M., Patterson, S., Harvey, J. J., Knight, S. C. (1994) Retrovirus-induced immunosuppression via blocking of dendritic cell migration and down-regulation of adhesion molecules. Immunology 82, 82-87.
15. Macatonia, S., Gompels, M., Pinching, A. J., Patterson, S., Knight, S. (1992) Antigen presentation by macrophages but not by dendritic cells in human immunodeficiency virus (HIV) infection. Immunology 75, 576-581.
16. Knight S. C. (1988) Lymphocyte proliferation assays. In Lymphocytes - A Practical Approach (G. G. B. Klaus, ed.), Oxford: ITRL Press, 189-207.