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Volumn 23, Issue 3, 1997, Pages 135-152

Adjuvant treatment of colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; FOLINIC ACID; LEVAMISOLE; MATRIX METALLOPROTEINASE INHIBITOR; OXALIPLATIN; SEMUSTINE; VINCRISTINE;

EID: 0030875029     PISSN: 03057372     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0305-7372(97)90035-9     Document Type: Review
Times cited : (16)

References (61)
  • 1
    • 0028158914 scopus 로고
    • Local recurrence of colorectal cancer: The problems, the mechanisms, management and adjuvant treatment
    • Abulafi, A. M. & Williams, N. S. (1994) Local recurrence of colorectal cancer: the problems, the mechanisms, management and adjuvant treatment. Br. J. Surg. 81: 7-17.
    • (1994) Br. J. Surg. , vol.81 , pp. 7-17
    • Abulafi, A.M.1    Williams, N.S.2
  • 2
    • 0015288972 scopus 로고
    • Studies correlating the growth rate of a tumor and it's metastases and providing evidence for tumor-related systemic growth-retarding factors
    • De Wys, W. D. (1972) Studies correlating the growth rate of a tumor and it's metastases and providing evidence for tumor-related systemic growth-retarding factors. Cancer Res. 32: 374-379.
    • (1972) Cancer Res. , vol.32 , pp. 374-379
    • De Wys, W.D.1
  • 3
    • 0023918858 scopus 로고
    • Adjuvant treatment in large bowel adenocarcinoma - Long-term results of a Southwest Oncology Group Study
    • Panettriere, F. J., Goodman, P. J., Conkinzi, J. J. et al. (1988) Adjuvant treatment in large bowel adenocarcinoma - long-term results of a Southwest Oncology Group Study. J. Clin. Oncol. 6: 947-955.
    • (1988) J. Clin. Oncol. , vol.6 , pp. 947-955
    • Panettriere, F.J.1    Goodman, P.J.2    Conkinzi, J.J.3
  • 4
    • 0021358193 scopus 로고
    • Efficacy of prolonged intermittent treatment with combined 5-FU and methyl CCNU following resection for carcinoma of the large bowel
    • Higgins, G. A. Jr., Amado, J. H., McElhinney, J. et al. (1984) Efficacy of prolonged intermittent treatment with combined 5-FU and methyl CCNU following resection for carcinoma of the large bowel. Cancer 53: 1-8.
    • (1984) Cancer , vol.53 , pp. 1-8
    • Higgins Jr., G.A.1    Amado, J.H.2    McElhinney, J.3
  • 5
    • 0006207082 scopus 로고
    • Adjuvant chemoimmuno and immunotherapy in stage B and C colorectal carcinoma
    • Abdi, E. A., Harbora, D., Hanson, J. et al. (1987) Adjuvant chemoimmuno and immunotherapy in stage B and C colorectal carcinoma. Proc. Am. Soc. Oncol. 6: 93.
    • (1987) Proc. Am. Soc. Oncol. , vol.6 , pp. 93
    • Abdi, E.A.1    Harbora, D.2    Hanson, J.3
  • 6
    • 0023855192 scopus 로고
    • Post operative adjuvant chemotherapy or BCG for colon cancer : Results from NSABP protocol C-01
    • Wolmark, N., Fisher, B., Rockette, H. et al. (1988) Post operative adjuvant chemotherapy or BCG for colon cancer : results from NSABP protocol C-01. J. Natl. Ca. Inst. 80: 30-36.
    • (1988) J. Natl. Ca. Inst. , vol.80 , pp. 30-36
    • Wolmark, N.1    Fisher, B.2    Rockette, H.3
  • 7
    • 0024397951 scopus 로고
    • Surgical adjuvant treatment of large bowel cancer; an evaluation of levamisole and the combination of levamisole and 5-FU. A study of the North Central Cancer Treatment Group (NCCTG) and the Mayo Clinic
    • Laurie, J. A., Moertel, C. G., Fleming, T. R. et al. (1989) Surgical adjuvant treatment of large bowel cancer; an evaluation of levamisole and the combination of levamisole and 5-FU. A study of the North Central Cancer Treatment Group (NCCTG) and the Mayo Clinic. J. Clin. Oncol. 7: 1447-1456.
    • (1989) J. Clin. Oncol. , vol.7 , pp. 1447-1456
    • Laurie, J.A.1    Moertel, C.G.2    Fleming, T.R.3
  • 8
    • 0025060806 scopus 로고
    • Levamisole and fluouracil for adjuvant treatment of resected colon cancer
    • Moertel, C. G., Fleming, T. H., MacDonald, J. S. et al. (1990) Levamisole and fluouracil for adjuvant treatment of resected colon cancer. N. Engl. J. Med. 322: 352-358.
    • (1990) N. Engl. J. Med. , vol.322 , pp. 352-358
    • Moertel, C.G.1    Fleming, T.H.2    MacDonald, J.S.3
  • 9
    • 0027247405 scopus 로고
    • Effect of levamisole on MHC Class I expression in colorectal and breast cancer cell lines
    • Goodrich, K. H., Alvarez, X., Holcombe, R. F. et al. (1993) Effect of levamisole on MHC Class I expression in colorectal and breast cancer cell lines. Cancer 72: 225-230.
    • (1993) Cancer , vol.72 , pp. 225-230
    • Goodrich, K.H.1    Alvarez, X.2    Holcombe, R.F.3
  • 11
    • 0027528855 scopus 로고
    • Multifocal leukoencephalopathy; occurrence during 5-FU and levamisole treatment and resolution after discontinuation of chemotherapy
    • Kimmel, D. W. & Schutt, A. J. (1993) Multifocal leukoencephalopathy; occurrence during 5-FU and levamisole treatment and resolution after discontinuation of chemotherapy. Mayo Clin. Proc. 68: 363-365.
    • (1993) Mayo Clin. Proc. , vol.68 , pp. 363-365
    • Kimmel, D.W.1    Schutt, A.J.2
  • 12
    • 0028216744 scopus 로고
    • Late mortality and levamisole. Adjuvant treatment in colorectal cancer
    • Chlebowski, R. T., Lillington, L., Nystrom, J. G. & Sayre, J. (1994) Late mortality and levamisole. Adjuvant treatment in colorectal cancer. Br. J. Cancer 69: 1094-1097.
    • (1994) Br. J. Cancer , vol.69 , pp. 1094-1097
    • Chlebowski, R.T.1    Lillington, L.2    Nystrom, J.G.3    Sayre, J.4
  • 13
    • 84944371744 scopus 로고
    • Adjuvant therapy for patients with colon and rectal cancer
    • NIH Consensus Conference
    • NIH Consensus Conference (1990) Adjuvant therapy for patients with colon and rectal cancer. JAMA 264: 1444-1450.
    • (1990) JAMA , vol.264 , pp. 1444-1450
  • 14
    • 0025152842 scopus 로고
    • Cancer of the colon and rectum
    • King's Fund Forum (1990) Cancer of the colon and rectum. Br. J. Surg. 77: 1063-1065.
    • (1990) Br. J. Surg. , vol.77 , pp. 1063-1065
  • 16
    • 0024829926 scopus 로고
    • 5-Fluouracil and folinic acid: Interesting biochemistry or effective treatment?
    • Kerr, D. J. (1989) 5-Fluouracil and folinic acid: interesting biochemistry or effective treatment? Br.J.Cancer 60: 807-808.
    • (1989) Br.J.Cancer , vol.60 , pp. 807-808
    • Kerr, D.J.1
  • 17
    • 0022624346 scopus 로고
    • Treatment of advanced colorectal and gatric adenocarcinomas with 5-fluouracil combined with high dose folinic acid
    • Machover, D., Goldschmidt, E., Chollet, P. et al. (1986) Treatment of advanced colorectal and gatric adenocarcinomas with 5-fluouracil combined with high dose folinic acid. J. Clin. Oncol. 4: 685-696.
    • (1986) J. Clin. Oncol. , vol.4 , pp. 685-696
    • Machover, D.1    Goldschmidt, E.2    Chollet, P.3
  • 18
    • 0019906743 scopus 로고
    • Treatment of advanced colorectal and gastric adenocarcinomas with 5-FU combined with high-dose folinic acid: A pilot study
    • Machover, D., Schwartzenberg, L., Goldshmidt, E. et al. (1982) Treatment of advanced colorectal and gastric adenocarcinomas with 5-FU combined with high-dose folinic acid: A pilot study. Cancer Treat. Rep. 66: 1803-1807.
    • (1982) Cancer Treat. Rep. , vol.66 , pp. 1803-1807
    • Machover, D.1    Schwartzenberg, L.2    Goldshmidt, E.3
  • 19
    • 0021130547 scopus 로고
    • Phase I-II trial of high-dose calcium leucovorin and 5-fluouracil in advanced colorectal cancer
    • Madajewicz, S., Petrelli, N., Rustum, Y. et al. (1984) Phase I-II trial of high-dose calcium leucovorin and 5-fluouracil in advanced colorectal cancer. Cancer Res. 44: 4667-4669.
    • (1984) Cancer Res. , vol.44 , pp. 4667-4669
    • Madajewicz, S.1    Petrelli, N.2    Rustum, Y.3
  • 20
    • 0026721532 scopus 로고
    • Modulation of 5-fluouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
    • Advanced Colorectal Analysis Project
    • Buyse, M., Piedbois, P., Rustum, Y. - Advanced Colorectal Analysis Project (1992) Modulation of 5-fluouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. J. Clin. Oncol. 10: 896-903.
    • (1992) J. Clin. Oncol. , vol.10 , pp. 896-903
    • Buyse, M.1    Piedbois, P.2    Rustum, Y.3
  • 21
    • 0029644482 scopus 로고
    • Efficacy of adjuvant fluouracil and folinic acid in colon cancer
    • IMPACT trial
    • IMPACT trial (1995) Efficacy of adjuvant fluouracil and folinic acid in colon cancer. Lancet 345: 939-944.
    • (1995) Lancet , vol.345 , pp. 939-944
  • 22
    • 0031022988 scopus 로고    scopus 로고
    • Controlled trial of fluouracil and low-dose leucovorin given for 6 months as post operative adjuvant therapy for colon cancer
    • O'Connell, M., Maillard, J., Kahn, M. J. et al. (1997) Controlled trial of fluouracil and low-dose leucovorin given for 6 months as post operative adjuvant therapy for colon cancer. J. Clin. Oncol. 15: 246-250.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 246-250
    • O'Connell, M.1    Maillard, J.2    Kahn, M.J.3
  • 23
    • 0027436244 scopus 로고
    • The benefit of leucovorin modulated 5-fluouracil as post operative adjuvant treatment for primary colon cancer : Results from the Natl. Surg. Adjuv. Breast and Bowel Project protocol C-03
    • Wolmark, N., Rockette, H., Fisher, B. et al. (1993) The benefit of leucovorin modulated 5-fluouracil as post operative adjuvant treatment for primary colon cancer : Results from the Natl. Surg. Adjuv. Breast and Bowel Project protocol C-03. J. Clin. Oncol. 11: 1879-1888.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 1879-1888
    • Wolmark, N.1    Rockette, H.2    Fisher, B.3
  • 24
    • 0023887810 scopus 로고
    • Adjuvant therapy of colorectal cancer. Why we still don't know
    • Buyse, M., Zeleniuch-Jacquotee, A. & Chambers, T. C. (1988) Adjuvant therapy of colorectal cancer. Why we still don't know. JAMA 259: 3571.
    • (1988) JAMA , vol.259 , pp. 3571
    • Buyse, M.1    Zeleniuch-Jacquotee, A.2    Chambers, T.C.3
  • 25
    • 0021360420 scopus 로고
    • The evaluation of low-dose pre-operative X-ray therapy in the management of operable rectal cancer: The results of a randomly controlled trial
    • Second report of the MRC Working Party (1984) The evaluation of low-dose pre-operative X-ray therapy in the management of operable rectal cancer: the results of a randomly controlled trial. Br. J. Surg. 71: 21-25.
    • (1984) Br. J. Surg. , vol.71 , pp. 21-25
  • 26
    • 0030583839 scopus 로고    scopus 로고
    • Randomised trial of surgery alone versus radiotherapy followed by surgery for potentially operable locally advanced rectal cancer
    • MRC Rectal Cancer Working Party (1996) Randomised trial of surgery alone versus radiotherapy followed by surgery for potentially operable locally advanced rectal cancer. Lancet 348: 1605-1610.
    • (1996) Lancet , vol.348 , pp. 1605-1610
  • 27
    • 0030583820 scopus 로고    scopus 로고
    • Randomised trial of surgery alone versus surgery followed by radiotherapy for mobile cancer of the rectum
    • MRC Rectal Cancer Working Party (1996) Randomised trial of surgery alone versus surgery followed by radiotherapy for mobile cancer of the rectum. Lancet 348: 1610-1614.
    • (1996) Lancet , vol.348 , pp. 1610-1614
  • 28
  • 29
    • 0019833688 scopus 로고
    • Adjuvant chemotherapy in cancer of the colon and rectum: Demonstration of effectiveness of prolonged 5-FU chemotherapy in a prospectively controlled randomised trial
    • Grage, T. B. & Moss, S. E. (1981) Adjuvant chemotherapy in cancer of the colon and rectum: demonstration of effectiveness of prolonged 5-FU chemotherapy in a prospectively controlled randomised trial. Surg. Clin. North Am. 61: 1321-1329.
    • (1981) Surg. Clin. North Am. , vol.61 , pp. 1321-1329
    • Grage, T.B.1    Moss, S.E.2
  • 30
    • 0023836214 scopus 로고
    • Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: Results from NSABP protocol R-01
    • Fisher, B., Wolmark, N., Rockette, H. et al. (1988) Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP protocol R-01. J. Natl. Cancer Inst. 80: 21-29.
    • (1988) J. Natl. Cancer Inst. , vol.80 , pp. 21-29
    • Fisher, B.1    Wolmark, N.2    Rockette, H.3
  • 31
    • 0022876509 scopus 로고
    • Survival after post operative combination treatment of rectal cancer
    • Douglas, H. O. Jr, Moertel, C. G., Mayer, R. J. et al. (1986) Survival after post operative combination treatment of rectal cancer. N. Engl. J. Med. 315: 1294-1295.
    • (1986) N. Engl. J. Med. , vol.315 , pp. 1294-1295
    • Douglas Jr., H.O.1    Moertel, C.G.2    Mayer, R.J.3
  • 32
    • 0026071185 scopus 로고
    • Effective surgical adjuvant therapy for high-risk rectal carcinoma
    • Krook, J. E., Moertel, C. G., Gunderson, L. L. et al. (1991) Effective surgical adjuvant therapy for high-risk rectal carcinoma. N. Engl. J. Med. 324: 709-715.
    • (1991) N. Engl. J. Med. , vol.324 , pp. 709-715
    • Krook, J.E.1    Moertel, C.G.2    Gunderson, L.L.3
  • 33
    • 0028136295 scopus 로고
    • Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluouracil with radiation therapy after curative surgery
    • O'Connoll, M. J., Martenson, J. A., Wieand, H. S. et al. (1994) Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluouracil with radiation therapy after curative surgery. N. Engl. J. Med. 331: 502-507.
    • (1994) N. Engl. J. Med. , vol.331 , pp. 502-507
    • O'Connoll, M.J.1    Martenson, J.A.2    Wieand, H.S.3
  • 34
    • 0001219577 scopus 로고    scopus 로고
    • The relative efficacy of 5-fluouracil/ leucovorin, 5-fluouracil/levamisole and 5-fluouracil/leucovorin/levamisole in patients with Dukes B and C carcinoma of the colon : First report of the NSABP protocol C-04
    • abstract
    • Wolmark, N., Rockette, H., Mamounas, E. P. et al. (1996) The relative efficacy of 5-fluouracil/ leucovorin, 5-fluouracil/levamisole and 5-fluouracil/leucovorin/levamisole in patients with Dukes B and C carcinoma of the colon : first report of the NSABP protocol C-04. Proc. Am. Soc. Clin. Oncol. 15: 205 (abstract).
    • (1996) Proc. Am. Soc. Clin. Oncol. , vol.15 , pp. 205
    • Wolmark, N.1    Rockette, H.2    Mamounas, E.P.3
  • 35
    • 0000215937 scopus 로고    scopus 로고
    • Fluouracil, leucovorin and levamisole. Adjuvant treatment for colon cancer: Preliminary results of INT 0089
    • abstract
    • Haller, D. G., Catalano, P. J., MacDonald, J. S. & Mayer, R. J. (1996) Fluouracil, leucovorin and levamisole. Adjuvant treatment for colon cancer: Preliminary results of INT 0089. Proc. Am. Soc. Clin. Oncol. 15: 211 (abstract).
    • (1996) Proc. Am. Soc. Clin. Oncol. , vol.15 , pp. 211
    • Haller, D.G.1    Catalano, P.J.2    MacDonald, J.S.3    Mayer, R.J.4
  • 36
    • 0000492867 scopus 로고    scopus 로고
    • A prospective evaluation of chemotherapy duration and regimen as surgical adjuvant treatment for high risk colon cancer
    • a colloborative trial of the North Central Cancer Treatment Group and the National Cancer Institute of Canada Clinical Trials Group abstract
    • O'Connell, M. J., Laurie, J. A., Shepherd, L. et al. (1996) a prospective evaluation of chemotherapy duration and regimen as surgical adjuvant treatment for high risk colon cancer ; a colloborative trial of the North Central Cancer Treatment Group and the National Cancer Institute of Canada Clinical Trials Group. Proc. Am. Soc. Clin. Oncol. 15: 209 (abstract).
    • (1996) Proc. Am. Soc. Clin. Oncol. , vol.15 , pp. 209
    • O'Connell, M.J.1    Laurie, J.A.2    Shepherd, L.3
  • 38
    • 0001567830 scopus 로고
    • End results of a multicentric randomised trial comparing 5-fluouracil in continuous systemic infusion (Cl) to bolus administration (B) in measurable metastatic colorectal cancer (MCC)
    • abstract
    • Rougier, Ph., Paillot, B., Laplanche et al. (1992) End results of a multicentric randomised trial comparing 5-fluouracil in continuous systemic infusion (Cl) to bolus administration (B) in measurable metastatic colorectal cancer (MCC). Proc. Am. Soc. Clin. Oncol. 11: 163 (abstract).
    • (1992) Proc. Am. Soc. Clin. Oncol. , vol.11 , pp. 163
    • Rougier, Ph.1    Paillot, B.2    Laplanche3
  • 39
    • 0000259297 scopus 로고
    • A prospectively randomised trial comparing 5-fluouracil bolus with low-dose folinic acid and 5-fluouracil bolus plus continuous infusion with high dose folinic acid for advanced colorectal cancer
    • abstract
    • De Grammont, A., Bosset, J. F., Milan, C. et al. (1995) A prospectively randomised trial comparing 5-fluouracil bolus with low-dose folinic acid and 5-fluouracil bolus plus continuous infusion with high dose folinic acid for advanced colorectal cancer. Proc. Am. Soc. Clin. Oncol. 14: 194 (abstract).
    • (1995) Proc. Am. Soc. Clin. Oncol. , vol.14 , pp. 194
    • De Grammont, A.1    Bosset, J.F.2    Milan, C.3
  • 40
    • 0029012118 scopus 로고
    • A phase II study of 5-fluouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group Study
    • Leichman, C. G., Fleming, T. R. & Muggia, F. M. (1995) A phase II study of 5-fluouracil and its modulation in advanced colorectal cancer: A Southwest Oncology Group Study. J. Clin. Oncol. 13: 1303-1311.
    • (1995) J. Clin. Oncol. , vol.13 , pp. 1303-1311
    • Leichman, C.G.1    Fleming, T.R.2    Muggia, F.M.3
  • 41
    • 0021848221 scopus 로고
    • A randomised controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer
    • Taylor, I., Machin, D. & Mullee, M. (1985) A randomised controlled trial of adjuvant portal vein cytotoxic perfusion in colorectal cancer. Br. J. Surg. 72: 359.
    • (1985) Br. J. Surg. , vol.72 , pp. 359
    • Taylor, I.1    Machin, D.2    Mullee, M.3
  • 42
    • 0024988530 scopus 로고
    • Adjuvant therapy of Dukes A, B and C adenocarcinoma of the colon with portal vein 5-FU hepatic infusion: Preliminary results of NSABP protocol C-02
    • Wolmark, N., Rockette, H., Wickerman, D. L. et al. (1990) Adjuvant therapy of Dukes A, B and C adenocarcinoma of the colon with portal vein 5-FU hepatic infusion: preliminary results of NSABP protocol C-02. J. Clin. Oncol. 8: 1466.
    • (1990) J. Clin. Oncol. , vol.8 , pp. 1466
    • Wolmark, N.1    Rockette, H.2    Wickerman, D.L.3
  • 43
    • 0343373541 scopus 로고    scopus 로고
    • Adjuvant portal vein infusion of 5-FU and heparin (PVI) in colorectal cancer: An EORTC-GIVIO Intergroup phase III trial
    • abstract
    • Sahmoud, T., Rougier, P., Nitti, D. et al. (1996) Adjuvant portal vein infusion of 5-FU and heparin (PVI) in colorectal cancer: An EORTC-GIVIO Intergroup phase III trial. Ann. Oncol. 7 (Suppl. 5): 33 (abstract).
    • (1996) Ann. Oncol. , vol.7 , Issue.5 SUPPL. , pp. 33
    • Sahmoud, T.1    Rougier, P.2    Nitti, D.3
  • 44
    • 0027995422 scopus 로고
    • The AXIS colorectal cancer trial: Randomisation of over 2000 patients
    • AXIS Steering Group (1994) The AXIS colorectal cancer trial: randomisation of over 2000 patients. Br. J. Surg. 81: 1672.
    • (1994) Br. J. Surg. , vol.81 , pp. 1672
  • 46
    • 0028101164 scopus 로고
    • Pharmacokinetic study of 5-Fluouracil in a novel dialysate solution; a longterm IP treatment approach for advancedcolorectal cancer
    • McArdle, C. S., Kerr, D. J., O'Gorman, P. et al. (1994) Pharmacokinetic study of 5-Fluouracil in a novel dialysate solution; a longterm IP treatment approach for advancedcolorectal cancer. Br. J. Cancer 70: 762-766.
    • (1994) Br. J. Cancer , vol.70 , pp. 762-766
    • McArdle, C.S.1    Kerr, D.J.2    O'Gorman, P.3
  • 47
    • 0010690240 scopus 로고    scopus 로고
    • Combined IV and IP chemotherapy with 5-fluouracil and leucovorin vs 5-Fluouracil and levamisole for adjuvant treatment of resected colon carcinoma
    • abstract
    • Scheithauer, W., Marczell, A., Depish, D. et al. (1996) Combined IV and IP chemotherapy with 5-fluouracil and leucovorin vs 5-Fluouracil and levamisole for adjuvant treatment of resected colon carcinoma. Proc. Am. Soc. Clin. Oncol. 15: 216 (abstract).
    • (1996) Proc. Am. Soc. Clin. Oncol. , vol.15 , pp. 216
    • Scheithauer, W.1    Marczell, A.2    Depish, D.3
  • 48
    • 0025997350 scopus 로고
    • ICI D1964; a quinazoline antifolate thymidylate synthease inhibitor that is a potent inhibitor of L1210 tumour cell growth in vitro and in vivo; a new agent for clinical study
    • Jackman, A. L., Taylor, G. A., Gibson, W. et al. (1991) ICI D1964; a quinazoline antifolate thymidylate synthease inhibitor that is a potent inhibitor of L1210 tumour cell growth in vitro and in vivo; a new agent for clinical study. Cancer Res. 51: 5579-5586.
    • (1991) Cancer Res. , vol.51 , pp. 5579-5586
    • Jackman, A.L.1    Taylor, G.A.2    Gibson, W.3
  • 49
    • 0001252836 scopus 로고
    • Tomudex ZD1694: Results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leukopenia
    • Cunningham, D., Zalcberg, J. R., Rath, U. et al. (1995) Tomudex ZD1694: results of a randomised trial in advanced colorectal cancer demonstrate efficacy and reduced mucositis and leukopenia. Eur. J. Cancer 31A: 1945-1954.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 1945-1954
    • Cunningham, D.1    Zalcberg, J.R.2    Rath, U.3
  • 50
    • 0000154770 scopus 로고
    • Phase I study of the new thymidylate synthetase inhibitor "TOMUDEX" ZD1694 in advanced malignancy
    • abstract
    • Clarke, J. S., Ward, J., De Boer, M. et al. (1994) Phase I study of the new thymidylate synthetase inhibitor "TOMUDEX" ZD1694 in advanced malignancy. Ann. Oncol. 5 (Suppl. 5): 132 (abstract).
    • (1994) Ann. Oncol. , vol.5 , Issue.5 SUPPL. , pp. 132
    • Clarke, J.S.1    Ward, J.2    De Boer, M.3
  • 51
    • 9044245305 scopus 로고    scopus 로고
    • ZD 1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. TOMUDEX colorectal cancer study group
    • Zalcberg, J. R., Cunningham, D., Van Cutsem, E. et al. (1996) ZD 1694: A novel thymidylate synthase inhibitor with substantial activity in the treatment of patients with advanced colorectal cancer. TOMUDEX colorectal cancer study group. J. Clin. Oncol. 14: 716-721.
    • (1996) J. Clin. Oncol. , vol.14 , pp. 716-721
    • Zalcberg, J.R.1    Cunningham, D.2    Van Cutsem, E.3
  • 52
    • 0010731605 scopus 로고
    • A Phase II trial of oxaliplatin: I-OHP in patients with colorectal cancer previously esistant to 5-fluouracil and folinic acid
    • abstract
    • Moreau, S., Machover, D., de Gramont, A. et al. (1993) A Phase II trial of oxaliplatin: I-OHP in patients with colorectal cancer previously esistant to 5-fluouracil and folinic acid. Proc. Am. Soc. Clin. Oncol. 12: 645 (abstract).
    • (1993) Proc. Am. Soc. Clin. Oncol. , vol.12 , pp. 645
    • Moreau, S.1    Machover, D.2    De Gramont, A.3
  • 53
    • 0027310715 scopus 로고
    • Oxaliplatin activity against metastatic colorectal cancer. A phase II study of 5 day continuous venous infusion at circadian rhythm modulated rate
    • Levi, F., Perpoint, B., Garufi, C. et al. (1993) Oxaliplatin activity against metastatic colorectal cancer. A phase II study of 5 day continuous venous infusion at circadian rhythm modulated rate. Eur. J. Cancer 29A: 1280-1284.
    • (1993) Eur. J. Cancer , vol.29 A , pp. 1280-1284
    • Levi, F.1    Perpoint, B.2    Garufi, C.3
  • 54
    • 12644306826 scopus 로고
    • Oxaliplatin with high dose folinic acid and 5Fluouracil 48Hr infusion in pre-treated metastatic colorectal cancer (CRC)
    • De Gramont, A., Vignoud, J., Tournigand, C. et al. (1995) Oxaliplatin with high dose folinic acid and 5Fluouracil 48Hr infusion in pre-treated metastatic colorectal cancer (CRC). Eur. J. Cancer 31A:716.
    • (1995) Eur. J. Cancer , vol.31 A , pp. 716
    • De Gramont, A.1    Vignoud, J.2    Tournigand, C.3
  • 55
    • 0000003860 scopus 로고    scopus 로고
    • 360 patient meta-analysis of studies of marimastat - A novel matrix metalloproteinase inhibitor
    • abstract
    • Millar, A. & Brown, P. (1996) 360 patient meta-analysis of studies of marimastat - a novel matrix metalloproteinase inhibitor. Annals Oncol. 7 (Suppl. 5): 123 (abstract).
    • (1996) Annals Oncol. , vol.7 , Issue.5 SUPPL. , pp. 123
    • Millar, A.1    Brown, P.2
  • 56
    • 0027512782 scopus 로고
    • Adjuvant ASI for human colorectal cancer: A 6.5 year median follow-up of a phase III prospective randomised trial
    • Hoover, H. C. Jr., Brandhorst, J. S. & Peters, L. C. (1993) Adjuvant ASI for human colorectal cancer: a 6.5 year median follow-up of a phase III prospective randomised trial. J. Clin. Oncol. 11: 390-399.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 390-399
    • Hoover Jr., H.C.1    Brandhorst, J.S.2    Peters, L.C.3
  • 57
    • 0343839113 scopus 로고
    • Colorectal carcinoma-specific antigen: Detection by means of monoclonl antibodies
    • Herlyn, M., Steplewski, Z., Herlyn, D. & Koprowski, H. (1979) Colorectal carcinoma-specific antigen: detection by means of monoclonl antibodies. Proc. Natl. Acad. Sci. USA. 76: 1438-1442.
    • (1979) Proc. Natl. Acad. Sci. USA , vol.76 , pp. 1438-1442
    • Herlyn, M.1    Steplewski, Z.2    Herlyn, D.3    Koprowski, H.4
  • 58
    • 0018890924 scopus 로고
    • Inhibition of growth of colorectal carcinoma in nude mice by monoclonal antibody
    • Herlyn, M., Steplewski, Z., Herlyn, M. F. & Koprowski, H. (1980) Inhibition of growth of colorectal carcinoma in nude mice by monoclonal antibody. Cancer Res. 40: 717-721.
    • (1980) Cancer Res. , vol.40 , pp. 717-721
    • Herlyn, M.1    Steplewski, Z.2    Herlyn, M.F.3    Koprowski, H.4
  • 59
    • 0025995425 scopus 로고
    • The therapeutic use of monoclonal antibodies in colorectal carcinoma
    • Mellstedt, H., Frodin, J. E., Masucci, G. et al. (1991) The therapeutic use of monoclonal antibodies in colorectal carcinoma. Semin. Oncol. 2: 462-477.
    • (1991) Semin. Oncol. , vol.2 , pp. 462-477
    • Mellstedt, H.1    Frodin, J.E.2    Masucci, G.3
  • 60
    • 0028224082 scopus 로고
    • Randomised trial of monoclonal antibody for adjuvant treatment of resected Dukes C colorectal carcinoma
    • Riethmuller, G., Schneider-Gadicke, E. & Schlimok, G. (1994) Randomised trial of monoclonal antibody for adjuvant treatment of resected Dukes C colorectal carcinoma. Lancet 343: 1177-1183.
    • (1994) Lancet , vol.343 , pp. 1177-1183
    • Riethmuller, G.1    Schneider-Gadicke, E.2    Schlimok, G.3
  • 61
    • 0027496518 scopus 로고
    • In vivo anti-tumour activity of 5-fluorocytosine on human colorectal cancer cells genetically modified to express cytosine deaminase
    • Huber, B. E., Austin, E. A., Good, S. S., Knick, V. C., Tibbel, S. & Richards, C. A. (1993) In vivo anti-tumour activity of 5-fluorocytosine on human colorectal cancer cells genetically modified to express cytosine deaminase. Cancer Res. 53: 4619-4626.
    • (1993) Cancer Res. , vol.53 , pp. 4619-4626
    • Huber, B.E.1    Austin, E.A.2    Good, S.S.3    Knick, V.C.4    Tibbel, S.5    Richards, C.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.