Randomised trial of surgery alone versus surgery followed by radiotherapy for mobile cancer of the rectum

Lancet

Volumn 348, Issue 9042, 1996, Pages 1610-1614

  Arnott, S J ^a  

^a ST BARTHOLOMEW S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER RECURRENCE; CANCER SURVIVAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; POSTOPERATIVE CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECTUM ANTERIOR RESECTION; RECTUM CANCER;

EID: 0030583820     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(96)05349-4     Document Type: Article

References (11)

1. Roswit B, Higgins GA, Keehn RJ. Pre-operative irradiation for carcinoma of the rectum and rectosigmoid colon: report of a National Veterans administration randomised study. Cancer 1975; 35: 1597-602.
2. MRC Working Party on Rectal Cancer. The evaluation of low-dose pre-operative X-ray therapy in the management of operable rectal cancer; results of a randomly controlled trial. Br J Surg 1984; 71: 21-25.
3. MRC Rectal Cancer Working Party. Randomised trial of surgery alone versus radiotherapy followed by surgery for potentially operable locally advanced rectal cancer. Lancet 1996; 348: 1605-10.
4. Balslev IB, Pedersen M, Teglbjaerg PS, et al. Post-operative radiotherapy in Dukes' B and C carcinoma of the rectum and rectosigmoid. Cancer 1986; 58: 22-28.
5. Fisher B, Wolmark N, Rockette H , et al. Post-operative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP protocol R-01. J Natl Cancer Inst 1988; 80: 21-29.
6. Gastrointestinal Tumour Study Group. Prolongation of the disase-free interval in surgically treated rectal carcinoma. N Engl J Med 1985; 312: 1464-72.
7. Treurniet-Donker AD, van Putten WLJ, Wereldsma JCL, et al. Post-operative radiation therapy for rectal cancer. Cancer 1991; 67: 2042-48.
8. Gray R, James R, Mossman J, Stenning SP. AXIS - a suitable case for treatment. Br J Cancer 1991; 63: 841-45.
9. Pahlman L, Glimelius B. Pre- and post-operative radiotherapy in rectal carcinoma: report from a randomised multicentre trial. Ann Surg 1990; 211: 187-95.
10. Adam IJ, Mohamdee MO, Martin IG, et al. Role of circumferential margin involvement in the local recurrence of rectal cancer. Lancet 1994; 341: 457-60.
11. AXIS Steering Group on behalf of the AXIS collaborators. The AXIS colorectal cancer trial - randomisation of over 2000 patients. Br J Surg 1994; 81: 1672.