Adenoviral-mediated delivery of gastrin-releasing peptide receptor results in specific tumor localization of a bombesin analogue in vivo

Clinical Cancer Research

Volumn 3, Issue 7, 1997, Pages 1187-1194

  Rosenfeld, Maryland E ^b   Rogers, Buck E ^a   Khazaeli, M B ^c   Mikheeva, Galina ^b   Raben, David ^a   Mayo, Matthew S ^c   Curiel, David T ^b   Buchsbaum, Donald J ^a  

^a The University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BOMBESIN; GASTRIN RELEASING PEPTIDE DERIVATIVE;

ADENOVIRUS; ANIMAL EXPERIMENT; ARTICLE; CANCER CELL CULTURE; EXPRESSION VECTOR; GENE TARGETING; HUMAN; HUMAN CELL; ISOTOPE LABELING; MOUSE; NONHUMAN; NUDE MOUSE; OVARY CARCINOMA; PRIORITY JOURNAL; RADIOIMMUNOTHERAPY; TUMOR LOCALIZATION;

ADENOVIRIDAE; ANIMALS; BOMBESIN; FEMALE; GENETIC VECTORS; HUMANS; IODINE RADIOISOTOPES; MICE; MICE, NUDE; OVARIAN NEOPLASMS; RADIOIMMUNOTHERAPY; RADIOLIGAND ASSAY; RECEPTOR, ERBB-2; RECEPTORS, BOMBESIN; RECOMBINANT PROTEINS; TISSUE DISTRIBUTION; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0030859031     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Buchsbaum, D. J. Experimental radioimmunotherapy and methods to increase therapeutic efficacy. In: D. M. Goldenberg (ed.), Cancer Therapy with Radiolabeled Antibodies, pp. 115-140. Boca Raton, FL: CRC Press, Inc., 1995.
2. Philben, V. J., Jakowatz, J. G., Beatty, B. G., Vlahos, W. G., Paxton, R. J., Williams, L. E., Shively, J. E., and Beatty, J. D. The effect of tumor CEA content and tumor size on tissue uptake of Indium 111-labeled anti-CEA monoclonal antibody. Cancer (Phila.), 57: 571-576, 1986.
3. Shockley, T. R., Lin, K., Sung, C., Nagy, J. A., Tompkins, R. G., Dedrick, R. L., Dvorak, H. F., and Yarmush, M. L. A quantitative analysis of tumor-specific monoclonal antibody uptake by human melanoma xenografts: effects of antibody immunological properties and tumor antigen expression levels. Cancer Res., 52: 357-366, 1992.
4. Lamberts, S. W. J., van der Lely, A-J., de Herder, W. W., and Hofland, L. J. Octreotide. N. Engl. J. Med., 334: 246-254, 1996.
5. Virgolini, I., Kurtaran, A., Raderer, M., Leimer, M., Angelberger, P., Havlik, E., Li, S., Scheithauer, W., Niederle, B., Valent, P., and Eichelr, H-G. Vasoactive intestinal peptide receptor scintigraphy. J. Nucl. Med., 36: 1732-1739, 1995.
6. 131I-labeled epidermal growth factor. Clin. Cancer Res., 2: 13-20, 1996.
7. Fischman, A. J., Babich, J. W., and Strauss, H. W. A ticket to ride: peptide radiopharmaceuticals. J. Nucl. Med., 34: 2253-2263, 1993.
8. Yokota, T., Milenic, D. E., Whitlow, M., and Schlom, J. Rapid tumor penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res., 52: 3402-3408, 1992.
9. Raben, D., Buchsbaum, D. J., Khazaeli, M. B., Rosenfeld, M. E., Gillespie, G. Y., and Curiel, D. T. Strategies to augment radioimmunotherapy via genetic induction of receptors for radioligand binding. Cancer Gene Ther., 2: 330, 1995.
10. Frankel, A., Tsao, M-S., and Viallet, J. Receptor subtype expression and responsiveness to bombesin in cultured human bronchial epithelial cells. Cancer Res., 54: 1613-1616, 1994.
11. Rogers, B. E., Stackhouse, M., Khazaeli, M. B., McLean, S., Kirkman, R.,. Ragland, T., Curiel, D. T., and Buchsbaum, D. J. Evaluation of a radioiodinated bombesin analogue as a potential radiotherapeutic agent. J. Nucl. Med., 37: 186P, 1996.
12. Yu, D., Wolf, J. K., Scanlon, M., Price, J. E., and Hung, M. C. Enhanced c-erbB-2/neu expression in human ovarian cancer cells correlates with more severe malignancy that can be suppressed by E1A. Cancer Res., 53: 891-898, 1993.
13. Deshane, J., Siegel, G. P., Alvarez, R. D., Wang, M., Feng, M., Cabrera, G., Liu, T., Kay, M., and Curiel, D. T. Targeted tumor killing via an intracellular antibody against erbB-2. J. Clin. Invest., 96: 2980-2989, 1995.
14. Rosenfeld, M. E., Wang, M., Siegal, G. P., Alvarez, R. D., Mikheeva, G., Krasnykh, V., and Curiel, D. T. Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma. J. Mol. Med., 74: 455-462, 1996.
15. Graham, F. L., and Prevec, L. Manipulation of adenovirus vectors. In: E. J. Murray (ed.), Methods in Molecular Biology, Volume 7: Gene Transfer and Expression Protocols, pp. 109-128. Clifton, NJ: The Humana Press, Inc., 1991.
16. Becker, T. C., Noel, R. J., Coats, W. S., Gomez-Foix, A. M., Alam, T., Gerard, R. D., and Newgard, C. B. Use of recombinant adenovirus for metabolic engineering of mammalian cells. Methods Cell Biol., 43: 161-189, 1994.
17. 2 in ovarian carcinoma induced to express the gastrin-releasing peptide receptor by adenoviral vector-mediated gene transfer. J. Nucl. Med., in press, 1997.
18. Kasprzyk, P. G., Song, S. U., DiFiore, P. P., and King, C. R. Therapy of an animal model of human gastric cancer using a combination of anti-erbB-2 monoclonal antibodies. Cancer Res., 52: 2771-2776, 1992.
19. Fraker, P. J., and Speck, J. C. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3α, 6α-diphenylglycoluril. Biochem. Biophys. Res. Commun., 80: 849-857, 1978.
20. Munson, P. J., and Rodbard, D. LIGAND: a versatile computerized approach for characterization of ligand binding systems. Anal. Biochem., 107: 220-239, 1980.
21. Labaune, J. P. Handbook of Pharmacokinetics, Toxicity Assessment of Chemicals. New York: John Wiley & Sons, Inc., 1989.
22. SAS/STAT User's Guide, Version 6, Fourth Edition, Volumes 1 and 2. Cary, NC: SAS Institute, Inc., 1989.
23. Rowlinson, G., Snook, D., Busza, A., and Epenetos, A. A. Antibody-guided localization of intraperitoneal tumors following intraperitoneal or intravenous antibody administration. Cancer Res., 47: 6528-6531, 1987.
24. Ward, B. G., Mather, S. J., Hawkins, L. R., Crowther, M. E., Shepherd, J. H., Granowska, M., Britton, K. E., and Slevin, M. L. Localization of radioiodine conjugated to the monoclonal antibody HMFG2 in human ovarian carcinoma: assessment of intravenous and intraperitoneal routes of administration. Cancer Res., 47: 4719-4723, 1987.
25. Roselli, M., Guadagni, F., Buonomo, O., Belardi, A., Vittorini, V., Mariani-Costantini, R., Greiner, J. W., Casciani, C. U., and Schlom, J. Systemic administration of recombinant interferon α in carcinoma patients up-regulates the expression of the carcinoma-associated antigens tumor-associated glycoprotein 72 and carcinoembryonic antigen. J. Clin. Oncol., 14: 2031-2042, 1996.
26. Raben, D., Buchsbaum, D. J., Khazaeli, M. B., Rosenfeld, M. E., Gillespie, G. Y., Grizzle, W. E., Liu, T., and Curiel, D. T. Enhancement of radiolabeled antibody binding and tumor localization through adenoviral transduction of the human carcinoembryonic antigen gene. Gene Ther., 3: 567-580, 1996.
27. Raben, D., Buchsbaum, D. J., Mikheeva, G., Grizzle, W. E., Khazaeli, M. B., Rogers, B., Curiel, D. T., and Garver, R. I., Jr. A strategy to augment efficacy of genetic radiation immunotherapy by use of conditionally replication-enabled adenovirus. Cancer Gene Ther., 3: S31, 1996.
28. Dion, L. D., Goldsmith, K. T., Strong, T. V., Bilbao, G., Curiel, D. T., and Garver, R. L. Jr. E1A RNA transcripts amplify adenovirus-mediated tumor reduction. Gene Ther., 3: 1021-1025, 1996.