Angiotensin II responses of vascular smooth muscle cells from hypertensive rats: Enhancement at the level of p42 and p44 mitogen activated protein kinase

British Journal of Pharmacology

Volumn 122, Issue 2, 1997, Pages 209-216

  Wilkie, Neil ^a   Ng, Leong L ^a   Boarder, Michael R ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Angiotensin II; Hypertension; MAPK; Protein kinase C; Spontaneously hypertensive rats (SHR); Vascular smooth muscle

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; GENISTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; NONHUMAN; PRIORITY JOURNAL; RAT; SMOOTH MUSCLE FIBER; SPONTANEOUSLY HYPERTENSIVE RAT; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; GENISTEIN; HYPERTENSION; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGEN-ACTIVATED PROTEIN KINASES; MUSCLE, SMOOTH, VASCULAR; PROTEIN KINASE C; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, ANGIOTENSIN; VASOCONSTRICTOR AGENTS;

EID: 0030856766     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701366     Document Type: Article

References (36)

1. BAINES, R., BROWN, C., NG, L.L. & BOARDER, M.R. (1996). Angiotensin II stimulated phospholipase C responses of two vascular smooth muscle derived cell lines: role of cyclic GMP. Hypertension, 27, 772-778.
2. BELTMAN, J., MCCORMIC, F. & COOK, S. (1996). The selective protein kinase C inhibitor Ro 31-8220 inhibits mitogen activated protein kinase phosphatase-1 (MKP-1) expression, induces c-Jun expression and activates Jun N-terminal kinase. J. Biol. Chem., 271, 27018-27024.
3. BENDHACK, L.M., SHARMA, R.M. & BHALLA, R.C. (1992). Altered signal transduction in vascular smooth muscle cells of spontaneously hypertensive rats. Hypertension, 19, (Suppl.II): II-142-II-148.
4. BERK, B.C. & CORSON, M.A. (1997). Angiotensin II signal transduction in vascular smooth muscle. Role of tyrosine kinases. Circ. Res., 80, 607-616.
5. BOLGER, C.T., LAIRD, F., JODOIN, A. & JARAMILLO, J. (1990). Vascular reactivity, tissue levels, and binding sites for endothelin: a comparison in the spontaneously hypertensive and Wistar-Kyoto rats. Can. J. Physiol. Pharmacol., 69, 406-413.
6. 2+ metabolism of isolated resistance arteries and cultures vascular myocytes of spontaneously hypertensive rats and Wistar-Kyoto normotensive rats. J. Hypertens., 8, 37-43.
7. BUNKENBERG, B., AMELSVOORT, T., ROGG, H. & WOOD, J.M. (1992). Receptor-mediated effect of angiotensin II on growth of vascular smooth muscle cells from spontaneously hypertensive rats. Hypertension, 20, 746-754.
8. BUTCHER, R.D., SCHOLLMANN, C. & MARME, D. (1993). Angiotensin II mediates intracellular signalling in vascular smooth muscle cells by activation of tyrosine-specific protein kinases and c-raf-1. Biochem. Biophys. Res. Commun., 196, 1280-1287.
9. CLARK-LEWIS, I., SANGHERA, J.S. & PELECH, S.L. (1991). Definition of a consensus sequence for peptide substrate recognition by p44mapk, the meiosis-activated myelin basic protein kinase. J. Biol. Chem., 266, 15180-15184.
10. + antiport activity in cultured skeletal muscle cells and vascular smooth muscle cells from the spontaneously hypertensive rat. Clin. Sci., 80, 509-516.
11. DAVIS, P.D., HILL, C.H., KEECH, E., LAWTON, G., NIXON, J.S., SEDGWICK, A.D., WADSWORTH, J., WESTMACOTT, D. & WILKINSON, S.E. (1989). Potent selective inhibitors of protein kinase C. FEBS Lett., 259, 61-63.
12. GRIENDLING, K.K., RITTENHOUSE, S.E., BROCK, T.A., EKSTEIN, L.S., GIMBRONE, M.A. & ALEXANDER, R.W. (1986). Sustained diacylglycerol formation from inositol phospholipids in angiotensin II stimulated vascular smooth muscle cells. J. Biol. Chem., 261, 5901-5906.
13. q-mediated mitogen-activated protein kinase activation. J. Biol. Chem., 270, 17148-17153.
14. ISHIDA, Y., KAWAHARA, Y., TSUDA, T., KOIDE, M. & YOKOYAMA, M. (1992). Involvement of MAP kinase activators in angiotensin II-induced activation of MAP kinases in cultured vascular smooth muscle cells. FEBS Letts., 310, 41-45.
15. KATO, T., FUKAMI, K., SHIBASAKI, F., HOMMA, Y. & TAKENAWA, T. (1992). Enhancement of phospholipase Cδ1 activity in the aorta of spontaneously hypertensive rats. J. Biol. Chem., 267, 6483-6487.
16. LEDUC, I., HADDAD, P., GIASSON, E. & MELOCHE, S. (1995). Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells. Mol. Pharmacol., 48, 582-592.
17. 2+-induced regulation of ion channel and MAP kinase functions. Nature, 376, 737-745.
18. 2+-dependent mitogen-activated protein kinase activity in spontaneously hypertensive rat vascular smooth muscle defines a hypertensive signal transduction phenotype. Circ. Res., 78, 962-970.
19. c-src antibodies inhibits the angiotensin II activation of phospholipase C-γ in rat aortic smooth muscle cells. J. Biol. Chem., 270, 15734-15738.
20. MOLLOY, C.J., TAYLOR, D.S. & WEBER, H. (1993). Angiotensin II Stimulation of rapid protein tyrosine phosphorylation and protein kinase activation in rat aortic smooth muscle cells. J. Biol. Chem., 268, 7338-7345.
21. MORTON, C., BAINES, R., MASOOD, I., NG, L.L. & BOARDER, M.R. (1995). Stimulation of two vascular smooth muscle derived cell lines by angiotensin II: differential second messenger responses leading to mitogenesis. Br. J. Pharmacol., 115, 361-367.
22. MURPHY, T.J., ALEXANDER, R.W., GRIENDLING, K.K., RUNGE, M.S. & BERNSTEIN, K.E. (1991). Isolation of a cDNA encoding the vascular type-1 angiotensin II receptor. Nature, 351, 233-236.
23. 2+ and phosphoinositide turnover metabolism induced by angiotensin II and [arg]vasopressin in vascular smooth muscle cells. J. Biol. Chem., 260, 4661-4670.
24. OSANI, J. & DUNN, M.J. (1992). Phospholipase C responses in cells from spontaneously hypertensive rats. Hypertension, 19, 446-455.
25. PAQUET, J.-L., BAUDOUIN-LEGROS, M., BRUNELLE, G. & MEYER, P. (1990). Angiotensin II-induced proliferation of aortic myocytes in spontaneously hypertensive rats. J. Hypertens., 8, 565-572.
26. PATEL, V., BROWN, C., GOODWIN, A., WILKIE, N. & BOARDER, M.R. (1996). Phosphorylation and activation of p42 and p44 mitogen-activated protein kinase are required for the P2 purinoceptor stimulation of endothelial prostacyclin production. Biochem. J., 320, 221-226.
27. PEACH, M.J. (1981). Molecular actions of angiotensin. Biochem. Pharmacol., 30, 2745-2751.
28. PEACH, M.J. & DOSTAL, D.E. (1990). The angiotensin H receptor and the actions of angiotensin II. J. Cardiovasc. Pharmacol., 16, (Suppl. 4) S25-S30.
29. RESINK, T.J., SCOTT-BURDEN, T., BAUR, U., BURGIN, M. & BUHLER, F.R. (1989). Enhanced responsiveness to angiotensin II in vascular smooth muscle cells from spontaneously hypertensive rats is not associated with alterations in protein kinase C. Hypertension, 14, 293-303.
30. SASAKI, K., YAMANO, S., BARDHAN, S., IWAI, N., MURRAY, J.J., HAGESAWA, Y., MATSUDA, Y. & INAGAMI, T. (1991). Cloning and expression of a complementary DNA encoding a bovine adrenal angiotensin II type-1 receptor. Nature, 351, 230-233.
31. SCHEIFFER, B., PAXTON, W.G., CHAI, Q., MARRERO, M.B. & BERNSTEIN, K.E. (1996). Angiotensin II controls p21 ras activity via pp60 c-sre. J. Biol. Chem., 271, 10329-10333.
32. q. Science, 251, 804-807.
33. TAYLOR, S.J., CHAE, H.Z., RHEE, S.G. & EXTON, J.H. (1991). Activation of the β1 isozyme of phospholipase C by α subunits of the Gq class of G proteins. Nature, 350, 516-518.
34. VAN BIESEN, T., HAWES, B.E., LUTTRELL, D.K., KRUEGER, K.M., TOUHARA, K. PORFIRI, E., SAKAUE, M., LUTTRELL, L.M. & LEFKOWITZ, R.J. (1995). Receptor-tyrosine-kinase and Gβγ-mediated MAP kinase activation by a common signalling mechanism. Nature, 376, 781-784.
35. WILKIE, N., MORTON, C., NG, L.L. & BOARDER, M.R. (1996). Stimulated mitogen-activated protein kinase is necessary but not sufficient for the mitogenic response to angiotensin II in cultured vascular smooth muscle cells: a role for phospholipase D. J. Biol. Chem., 271, 32447-32453.
36. i-coupled acetylcholine muscarinic m2 receptor activation of mitogen-activated protein (MAP) kinase kinase and MAP kinase. J. Biol. Chem., 268, 19196-19199.