Catalytic enantioselective tandem carbonyl ylide formation-cycloaddition

Tetrahedron Letters

Volumn 38, Issue 36, 1997, Pages 6471-6472

  Hodgson, David M ^a   Stupple, Paul A ^a   Johnstone, Craig ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

POLYCYCLIC HYDROCARBON; TETRAHYDROPYRAN DERIVATIVE;

ARTICLE; CATALYSIS; CHIRALITY; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0030840478     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01480-9     Document Type: Article

References (13)

1. Hodgson, D. M.; Bailey, J. M.; Harrison, T. Tetrahedron Lett. 1996, 37, 4623-4626.
2. Doyle, M. P.; McKervey, M. A. Chem. Commun. 1997, 983-989; Davies, H. M. L.; Hansen, T.; Rutberg, J. Bruzinski, P. R. Tetrahedron Lett. 1997, 38, 1741-1744.
3. Doyle, M. P.; McKervey, M. A. Chem. Commun. 1997, 983-989; Davies, H. M. L.; Hansen, T.; Rutberg, J. Bruzinski, P. R. Tetrahedron Lett. 1997, 38, 1741-1744.
4. Calter, M. A. Curr. Org. Chem. 1997, 1, 37-70.
5. Padwa, A.; Weingarten, M. D. Chem. Rev. 1996, 96, 223-269.
6. Padwa, A.; Austin, D. J.; Hornbuckle, S. F. J. Org. Chem. 1996, 61, 63-72.
7. Ye, T.; Fernández García, C.; McKervey, M. A. J. Chem. Soc. Perkin Trans. 1 1995, 1373-1379.
8. 3N, MeCN).
9. 3N, MeCN).
10. Padwa, A.; Hornbuckle, S. F.; Fryxell, G. E.; Zhang, Z. J. J. Org. Chem. 1992, 57, 5747-5757.
11. Isolated total yields of chromatographically homogeneous spectroscopically pure products are reported.
12. 2 then MeOH, p-TSA) respectively.
13. 4 are now commercially available from Aldrich.