The effect of vitamin D upplementation on the bone mineral density of the femoral neck is associated with vitamin D receptor genotype

Journal of Bone and Mineral Research

Volumn 12, Issue 8, 1997, Pages 1241-1245

  Graafmans, W C ^a   Lips, P ^a,b   Ooms, M E ^a   Van Leeuwen, J P T M ^c   Pols, H A P ^c   Uitterlinden, A G ^c  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

VITAMIN D; VITAMIN D RECEPTOR;

AGED; ARTICLE; BONE DENSITY; BONE MINERAL; DIET SUPPLEMENTATION; FEMALE; FEMUR NECK; FRACTURE; HORMONE RECEPTOR INTERACTION; HUMAN; MAJOR CLINICAL STUDY; OSTEOPOROSIS; VITAMIN D METABOLISM;

AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; BODY MASS INDEX; BONE DENSITY; CALCIUM, DIETARY; CHOLECALCIFEROL; DENSITOMETRY, X-RAY; FEMALE; FEMORAL NECK FRACTURES; FEMUR NECK; GENOTYPE; HUMANS; LONGITUDINAL STUDIES; OSTEOPOROSIS, POSTMENOPAUSAL; RECEPTORS, CALCITRIOL;

EID: 0030833612     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.8.1241     Document Type: Article

References (20)

1. Lips P, Obrant KJ 1991 The pathogenesis and treatment of hip fractures. Osteoporos Int 1:218-231.
2. Ooms ME, Roos JC, Bezemer PD, van der Vijgh WJ, Bouter LM, Lips P 1995 Prevention of bone loss by vitamin D supplementation in elderly women: A randomized double-blind trial. J Clin Endocrinol Metab 80:1052-1058.
3. 3 and calcium to prevent hip fractures in elderly women. N Engl J Med 327:1637-1642.
4. Morrison NA, Qi JC, Tokita A, et al. 1994 Prediction of bone density from vitamin D receptor alleles. Nature (London) 367:284-287.
5. Fleet JC, Harris SS, Wood RJ, Dawson-Hughes B 1995 The BsmI vitamin D receptor restriction fragment length polymorphism (BB) predicts low bone density in premenopausal black and white women. J Bone Miner Res 10:985-990.
6. Krall EA, Parry P, Lichter JB, Dawson-Hughes B 1995 Vitamin D receptor alleles and rates of bone loss: Influences of years since menopause and calcium intake. J Bone Miner Res 10:978-984.
7. Kroger H, Mahonen A, Ryhannen S, Turunen AM, Alhava E, Maenpaa P 1995 Vitamin D receptor genotypes and bone mineral density. Lancet 345:1238.
8. Garnero P, Borel O, Sornay-Rendu E, Delmas P 1995 Vitamin D receptor gene polymorphisms do not predict bone turnover and bone mass in healthy premenopausal women. J Bone Miner Res 10:1283-1288.
9. Ferrari S, Rizzoli R, Chevalley T, Slosman D, Eisman JA, Bonjour JP 1995 Vitamin-D-receptor-gene polymorphisms and change in lumbar-spine bone mineral density. Lancet 345: 423-424.
10. Howard G, Nguyen T, Morrison N, Wantanabe T, Sambrook P, Eisman J, Kelly PJ 1995 Genetic influences on bone density: Physiological correlates of vitamin D receptor gene alleles in premenopausal women. J Clin Endocrinol Metab 80: 2800-2805.
11. Matsuyama T, Ishii S, Tokita A, Yabuta K, Yamamori S, Morrison NA, Eisman JA 1995 VDR gene polymorphisms and vitamin D analog treatment in Japanese. Lancet 345: 1238-1239.
12. Lips P, Graafmans WC, Ooms ME, Bezemer PD, Bouter LM 1996 Vitamin D supplementation and fracture incidence in elderly persons: A randomized, placebo-controlled clinical trial. Ann Intern Med 124:400-406.
13. Elders PJM, Netelenbos JC, Lips P, Khoe E, van Ginkel FC, Hulshof KFAM, van der Stell PF 1989 Perimenopausal bone mass and risk factors. Bone Miner 7:123-132.
14. Genant HK, Faulkner KG, Gluer CC, Engelke K 1993 Bone densitometry: Current assessment. Osteoporos Int 3 (Suppl 1):91-97.
15. Hackeng WHL, Lips P, Netelenbos JC, Lips CJM 1986 Clinical implications of estimation of intact parathyroid hormone (PTH) versus total immunoreactivity PTH in normal subjects and hyperparathyroid subjects. J Clin Endocrinol Metab 63:447-453.
16. Uitterlinden AG, Pols HAP, Burger H, et al. 1996 A large scale population based study of the association of vitamin D receptor gene polymorphisms and bone mineral density. J Bone Miner Res 11:1241-1248.
17. Riggs BL, Nguyen T, Melton III LJ, et al. 1995 The contribution of vitamin D receptor gene alleles to the determination of bone mineral density in normal and osteoporotic women. J Bone Miner Res 10:991-996.
18. Salamone LM, Ferrell R, Black DM, Palermo L, Epstein RS, Petro N, Steadman N, Kuller LH, Cauley JA 1996 The association between vitamin D receptor gene polymorphisms and bone mineral density at the spine, hip and whole-body in premenopausal women. Osteoporos Int 6:63-68.
19. Meunier PJ, Lindsay R 1996 Editorial. Osteoporos Int 6:187-188.
20. Houston LA, Grant SFA, Reid DM, Ralston SH 1996 Vitamin D receptor polymorphism, bone mineral density, and osteoporotic vertebral fracture: Studies in a UK population. Bone 18:249-252.