The peptide endothelin receptor antagonist, TAK-044, produces sustained inhibition of endothelin-1 mediated arteriolar vasoconstriction

British Journal of Clinical Pharmacology

Volumn 44, Issue 4, 1997, Pages 377-383

  Ferro, C J ^a   Haynes, W G ^a   Johnston, N R ^a   Lomax, C C ^a   Newby, D E ^a   Webb, D J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Endothelin; Endothelin antagonists; Forearm blood flow; Humans; Pharmacodynamics

Indexed keywords

ENDOTHELIN 1; ENDOTHELIN RECEPTOR ANTAGONIST; PLACEBO; TAK 044;

ADULT; ARTERIOLE; ARTICLE; BRACHIAL ARTERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOSE RESPONSE; DRUG EFFECT; FOREARM BLOOD FLOW; HUMAN; HUMAN EXPERIMENT; INTRAVENOUS DRUG ADMINISTRATION; MALE; NORMAL HUMAN; PHARMACODYNAMICS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; VASOCONSTRICTION; VEIN OCCLUSION PLETHYSMOGRAPHY;

EID: 0030817234     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1997.00595.x     Document Type: Article

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