The nuclear matrix and apoptosis

Histochemistry and Cell Biology

Volumn 108, Issue 1, 1997, Pages 1-10

  Martelli, Alberto M ^a   Bareggi, Renato ^a   Bortul, Roberta ^a   Grill, Vittorio ^a   Narducci, Paola ^a   Zweyer, Marina ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; ENDONUCLEASE; NUCLEAR PROTEIN;

ANIMAL CELL; APOPTOSIS; CELL DEATH; CELL DESTRUCTION; CELL LINE; CELL NUCLEUS MATRIX; CELL STRUCTURE; CONTROLLED STUDY; ETIOLOGY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW;

ANIMALS; APOPTOSIS; ENDOPEPTIDASES; HUMANS; HYDROLYSIS; NUCLEAR MATRIX; NUCLEAR PROTEINS;

ANIMALIA;

EID: 0030816348     PISSN: 09486143     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004180050140     Document Type: Review

References (87)

1. Arends MJ, Wyllie AH (1991) Apoptosis: mechanisms and roles in pathology. Int Rev Exp Pathol 32:223-254
2. Arends MJ, Morris RG, Wyllie AH (1990) Apoptosis: the role of endonuclease. Am J Pathol 136:593-608
3. Belgrader P, Siegel AJ, Berezney R (1991a) A comprehensive study on the isolation and characterization of the HeLa S3 nuclear matrix. J Cell Sci 98:281-291
4. Belgrader P, Dey R, Berezney R (1991b) Molecular cloning of matrin 3. A 125-kilodalton protein of the nuclear matrix contains an extensive acidic domain. J Biol Chem 266:9893-9899
5. Berezney R (1991) The nuclear matrix: a heuristic model for investigating genomic organization and function in the cell nucleus. J Cell Biochem 47:109-123
6. Berezney R, Mortillaro MJ, Ma H, Wei X, Samarabandu J (1995) The nuclear matrix: a structural milieu for genomic function. Int Rev Cytol 162A:1-65
7. Bicknell GR, Snowden RT, Cohen GM (1994) Formation of high molecular mass DNA fragments is a marker of apoptosis in the human leukemic cell line, U937. J Cell Sci 107:2483-2489
8. Bortner CD, Oldenburg NBE, Cidlowski JA (1995) The role of DNA fragmentation in apoptosis. Trends Cell Biol 5:21-26
9. Boulikas T (1995) Chromatin domains and prediction of MAR sequences. Int Rev Cytol 162A:279-388
10. Brancolini C, Schneider C (1991) Change in the expression of a nuclear matrix-associated protein is correlated with cellular transformation. Proc Natl Acad Sci USA 88:6936-6940
11. Casciola-Rosen LA, Miller DK, Anhalt GJ, Rosen A (1994) Specific cleavage of the 70-kDa protein component of the U1 small nuclear ribonucleoprotein is a characteristic feature of apoptotic cell death. J Biol Chem 269:30757-30760
12. Dickinson LA, Joh T, Kohwi Y, Kohwi-Shigematsu T (1992) A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition. Cell 70:631-645
13. Dini L, Coppola S, Ruzittu MT, Ghibelli L (1996) Multiple pathways for apoptotic DNA fragmentation. Exp Cell Res 223:340-347
14. Djabali K, Portier MM, Gros F, Blobel G, Georgatos SD (1991) Network antibodies identify nuclear lamin B as a physiological attachment site for peripherin intermediate filaments. Cell 64:109-121
15. Dworetzky SI, Fey EG, Penman S, Lian JB, Stein JL, Stein GS (1990) Progressive changes in the protein composition of the nuclear matrix during rat osteoblast differentiation. Proc Natl Acad Sci USA 87:4605-4609
16. Earnshaw WC (1995) Nuclear changes in apoptosis. Curr Biol 7:337-343
17. Falcieri E, Martelli AM, Bareggi R, Cataldi A, Cocco L (1993) The protein kinase inhibitor staurosporine induces morphological changes typical of apoptosis in MOLT-4 cells without concomitant DNA fragmentation. Biochem Biophys Res Commun 193:19-25
18. Falcieri E, Gobbi P, Zamai L, Faenza I, Vitale M (1994a) Nuclear pore in the apoptotic cell. Histochem J 26:754-763
19. Falcieri E, Zamai L, Santi S, Cinti C, Gobbi P, Bosco D, Cataldi A, Betts C, Vitale M (1994b) The behaviour of nuclear domains in the course of apoptosis. Histochemistry 102:221-231
20. Fey EG, Penman S (1988) Nuclear matrix proteins reflect cell type of origin in cultured human cells. Proc Natl Acad Sci USA 85:121-125
21. Fields AP, Kaufmann SH, Shaper JH (1986) Analysis of the internal nuclear matrix. Oligomers of a 38 kD nucleolar polypeptide stabilized by disulfide bonds. Exp Cell Res 164:139-153
22. Fimia GM, Gottifreddi V, Passananti C, Maione R (1996) Double-stranded internucleosomal cleavage of apoptotic DNA is dependent on the degree of differentiation in muscle cells. J Biol Chem 271:15575-15579
23. Fraser MJ, Tynan SJ, Papaioannu A, Ireland CM, Pittman SM (1996) Endo-exonuclease of human leukaemic cells: evidence for a role in apoptosis. J Cell Sci 109:2343-2360
24. Georgatos SD, Blobel G (1987) Lamin constitutes an intermediate filament attachment site at the nuclear envelope. J Cell Biol 105:117-125
25. Getzenberg RH, Coffey DS (1990) Tissue specificity of the hormonal response in sex accessory tissues is associated with nuclear matrix protein patterns. Mol Endocrinol 4:1336-1342
26. Giancotti V, Bandiera A, Sindici C, Perissin L, Crane-Robinson C (1996) Calcium-dependent ADP-ribosylation of high-mobility-group I (HMGI) proteins. Biochem J 317:865-870
27. Hakes DJ, Berezney R (1991) Molecular cloning of matrin F/G: a DNA binding protein of the nuclear matrix that contains putative zinc finger motifs. Proc Natl Acad Sci USA 88:6186-6190
28. Hale AJ, Smith CA, Sutherland LC, Stoneman VEA, Longthorne VL, Culhane AC, Williams GT (1996) Apoptosis: molecular regulation of cell death. Eur J Biochem 236:1-26
29. He DC, Nickerson JA, Penman S (1990) Core filaments of the nuclear matrix. J Cell Biol 110:569-580
30. He D, Zeng C, Brinkley BR (1995) Nuclear matrix proteins as structural and functional components of the mitotic apparatus. Int Rev Cytol 162B:1-74
31. Hozak P, Sasseville AM-J, Raymond Y, Cook PR (1995) Lamin proteins form an internal nucleoskeleton as well as a peripheral lamina in human cells. J Cell Sci 108:635-644
32. Hsu H-L, Yeh N-H (1996) Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis. J Cell Sci 109:277-288
33. Jackson DA, Cook PR (1995) The structural basis of nuclear function. Int Rev Cytol 162A:125-149
34. Jackson DA, Dickinson P, Cook PR (1990) The size of chromatin loops in HeLa cells. EMBO J 9:567-571
35. Kass GEN, Eriksson JE, Weis M, Orrenius S, Chow SC (1996) Chromatin condensation during apoptosis requires ATP. Biochem J 318:749-752
36. Kaufmann SH (1989) Induction of endonucleolytic DNA cleavage in human acute myelogenous leukemia cells by etoposide, camptothecin, and other cytotoxic anticancer drugs: a cautionary note. Cancer Res 49:5870-5878
37. Kaufmann SH, Brunet G, Talbot B, Lamarr D, Dumas C, Shaper JH, Poirier G (1991) Association of poly(ADP-ribose) polymerase with the nuclear matrix: the role of intermolecular disulfide bond formation, RNA retention, and cell type. Exp Cell Res 192:524-535
38. Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE, Poirier GG (1993) Specific proteolytic cleavage of poly(ADP-ribose) polymerase: an early marker of chemotherapy-induced apoptosis. Cancer Res 53:3976-3985
39. Kerr JFR, Wyllie AH, Currie AR (1972) Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257
40. Lagarkova MA, Iarovaia OV, Razin SV (1995) Large-scale fragmentation of mammalian DNA in the course of apoptosis proceeds via excision of chromosomal DNA loops and their oligomers. J Biol Chem 270:20239-20241
41. Lazebnik YA, Cole S, Cooke CA, Nelson WG, Earnshaw WC (1993) Nuclear events of apoptosis in vitro in cell-free mitotic extracts: a model system for analysis of the active phase of apoptosis. J Cell Biol 123:7-22
42. Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG, Earnshaw WC (1994) Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE. Nature 371:346-347
43. Lazebnik YA, Takahashi A, Moir RD, Goldman RD, Poirier GG, Kaufmann SH, Earnshaw WC (1995a) Studies of the lamin proteinases reveal multiple parallel biochemical pathways during apoptotic execution. Proc Natl Acad Sci USA 92:9042-9046
44. Lazebnik YA, Takahashi A, Poirier GG, Kaufmann SH, Earnshaw WC (1995b) Characterization of the execution phase of apoptosis in vitro using extracts from condemned-phase cells. J Cell Sci Suppl 19:41-49
45. Lebel S, Raymond Y (1984) Lamin B from rat liver nuclei exists both as a lamina protein and as an intrinsic membrane protein. J Biol Chem 259:2693-2696
46. 1. Cell 70:949-959
47. Ludérus MEE, Blaauwen JL den, Smit OJ de, Compton DA, Driel R van (1994) Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove. Mol Cell Biol 14:6297-6305
48. Madsen KR, Fiskum G, Clawson GA (1992) Regulation of nuclear scaffold protease activity by calcium. Exp Cell Res 187:343-345
49. 1 and DNA fragmentation in isolated thymocyte nuclei. J Biol Chem 271:22398-22406
50. Miller T, Beausang LA, Meneghini M, Lidgard G (1993) Death-induced changes to the nuclear matrix: the use of antinuclear matrix antibodies to study agents of apoptosis. Biotechniques 15:1042-1047
51. Miller TE, Beausang LA, Meneghini M, Lidgard G (1994) Cell death and nuclear matrix proteins. In: Tomei LD, Cope FO (eds) Apoptosis II: the molecular basis of apoptosis in disease. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp 357-376
52. Moir RD, Spann TP, Goldman RD (1995) The dynamic and possible functions of nuclear lamins. Int Rev Cytol 162B:141-182
53. Nakayasu H, Berezney R (1991) Nuclear matrins: identification of the major nuclear matrix proteins. Proc Natl Acad Sci USA 88:10312-10316
54. 1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei. J Immunol 154:3788-3795
55. Nicholson DW, Ali A, Thornberry NA, Vaillancourt JP, Ding CK, Gallant M, Gareau Y, Griffin PR, Labelle M, Lazebnik YA, Munday NA, Raju SM, Smulson ME, Yamin T-T, Yu VL, Miller DK (1995) Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature 376:37-43
56. Nickerson JA, Blencowe BJ, Penman S (1995) The architectural organization of nuclear metabolism. Int Rev Cytol 162A:67-123
57. Noon YS, Kim JW, Wang KW, Kim YS, Choi KH, Joe CO (1996) Poly(ADP-ribosyl)ation of histone H1 correlates with internucleosomal DNA fragmentation during apoptosis. J Biol Chem 271:9129-9134
58. Oberhammer FA, Fritsch G, Schmied M, Pavelka M, Printz, D, Purchio T, Lassmann H, Schulte-Hermann R (1993a) Condensation of ther chromatin at the nuclear membrane of an apoptotic nucleus is not associated with activation of an endonuclease. J Cell Sci 104:317-326
59. Oberhammer F, Wilson JW, Dive C, Morris ID, Hickman JA, Wakeling AE, Walker PR, Sikorska M (1993b) Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J 12:3679-3684
60. Oberhammer FA, Hochegger K, Froschl G, Tiefenbacher R, Pavelka M (1994) Chromatin condensation during apoptosis is accompanied by degradation of lamin A+B, without enhanced activation of cdc2 kinase. J Cell Biol 126:827-837
61. Patterson SD, Grossman JS, D'Andrea P, Latter GI (1995) Reduced numatrin/B23/nucleophosmin labeling in apoptotic Jurkat T-lymphoblasts. J Biol Chem 270:9429-9436
62. Paulson JR, Laemmli UK (1977) The structure of historic-depleted metaphase chromosomes. Cell 12:817-828
63. Pongracz J, Tuffley W, Johnson GD, Deacon EM, Burnett D, Stockley RA, Lord JM (1995) Changes in protein kinase C isoenzyme expression associated with apoptosis in U937 myelomonocytic cells. Exp Cell Res 218:430-438
64. Renz A, Fackelmayer FO (1996) Purification and molecular cloning of the scaffold attachment factor B (SAF-B), a novel human nuclear protein that specifically binds to S/MAR-DNA. Nucleic Acids Res 24:843-849
65. Reipert S, Reipert BM, Hickman JA, Allen TD (1996) Nuclear pore clustering is a consistent feature of apoptosis in vitro. Cell Death Differ 3:131-139
66. Saredi A, Howard L, Compton DA (1996) NuMA assembles into an extensive filamentous structure when expressed in the cell cytoplasm. J Cell Sci 109:619-630
67. Schwarzacher HG, Wachtler F (1993) The nucleolus. Anat Embryol 188:515-536
68. Strasberg Rieber M, Rieber M (1992) Accessibility to DNA in carcinoma chromatin is promoted by nanomolar okadaic acid; effect on AT-rich DNA binding proteins. Cancer Res 52:6397-6399
69. Strouboulis J, Wolffe AP (1996) Functional compartmentalization of the nucleus. J Cell Sci 109:1991-2000
70. Stuppia L, Gobbi P, Zamai L, Palka G, Vitale M, Falcieri E (1996) Morphometric and functional study of apoptotic cell chromatin. Cell Death Differ 3:397-405
71. Takahashi A, Alnemri ES, Lazebnik YA, Fernandes-Alnemri T, Litwack G, Moir RD, Goldman RD, Poirier GG, Kaufmann SH, Earnshaw WC (1996) Cleavage of lamin A by Mch 2 α but not CPP32: multiple interleukin-1β-converting enzyme-related proteases with distinct substrate recognition proteins are active in apoptosis. Proc Natl Acad Sci USA 93:8395-8400
72. Tawfic S, Olson MOJ, Ahmed K (1995) Role of protein phosphorylation in post-translational regulation of protein B23 during programmed cell death in the prostate gland. J Biol Chem 270: 21009-21015
73. Thompson CB (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267:1456-1462
74. Tinnemans MMFJ, Lenders M-HJH, Velde GPM ten, Ramaekers FCS, Schutte B (1995) Alterations in cytoskeletal and nuclear matrix-associated proteins during apoptosis. Eur J Cell Biol 68:35-46
75. Tomei LD, Cope FO (eds) (1994) Apoptosis II: the molecular basis of apoptosis in disease. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
76. Trubiani O, Borgatti P, Di Primio R (1994) Protein kinase C modulation in apototic rat thymocytes: an ultrastructural analysis. Histochemistry 102:311-316
77. Ucker DS, Obermiller PS, Eckhart W, Apgar JR, Berger NA, Meyers J (1992) Genome digestion is a dispensable consequence of physiological cell death mediated by cytotoxic T-lymphocytes. Mol Cell Biol 12:3060-3069
78. Vaux DL, Strasser A (1996) The molecular biology of apoptosis. Proc Natl Acad Sci USA 93:2239-2244
79. Weaver VM, Carson CE, Walker PR, Chaly N, Lach B, Raymond Y, Brown DL, Sikorska M (1996) Degradation of nuclear matrix and DNA cleavage in apoptotic thymocytes. J Cell Sci 109:45-56
80. Williams GT (1991) Programmed cell death: apoptosis and oncogenesis. Cell 65:1097-1098
81. Williams GT (1994) Apoptosis in the immune system. J Pathol 173:1-4
82. Yaganisawa J, Ando J, Nakayama J, Kohwi Y, Kohwi-Shigematsu T (1996) A matrix attachment region (MAR)-binding activity due to a p114 kilodalton protein is found only in human breast carcinomas and not in normal and benign breast disease tissues. Cancer Res 56:457-462
83. Yang CH, Lambie EJ, Snyder M (1992) NuMA: an unusually long coiled-coil related protein in mammalian nucleus. J Cell Biol 116:1303-1317
84. Zeng C, He D, Brinkley BR (1994) Localization of NuMA protein isoforms in the nuclear matrix of mammalian cells. Cell Motil Cytoskeleton 29:167-176
85. Zhivotovsky B, Gahm A, Ankarcrona M, Nicotera P, Orrenius S (1995) Multiple proteases are involved in thymocyte apoptosis. Exp Cell Res 221:404-412
86. Zweyer M, Bareggi R, Grill V, Soranzo MR, Marugg RA, Riederer BM, Narducci P, Martelli AM (1995) Behavior of nuclear matrix proteins during camptothecin-induced apoptosis in HL-60 human leukemia cells. Exp Cell Res 221:27-40
87. Zweyer M, Riederer BM, Ochs RL, Fackelmayer FO, Kohwy-Shigematsu T, Bareggi R, Narducci P, Martelli AM (1997) Association of nuclear matrix proteins with granular and threaded nuclear bodies in cell lines undergoing apoptosis. Exp Cell Res 230:325-336