750 MHz HPLC-NMR spectroscopic identification of rat microsomal metabolites of phenoxypyridines

Journal of Pharmaceutical and Biomedical Analysis

Volumn 16, Issue 3, 1997, Pages 481-489

  Corcoran, Olivia ^a   Spraul, Manfred ^b   Hofmann, Martin ^b   Ismail, Ismail M ^c   Lindon, John C ^a   Nicholson, Jeremy K ^a  

^a UNIVERSITY OF LONDON   (United Kingdom)

^b Bruker Analytik GmbH   (Germany)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

750 MHz HPLC NMR; Fluorophenoxypyridines; Metabolism; Rat microsomes

Indexed keywords

3 AMINO 2 (2 FLUOROPHENOXY)PYRIDINE; 3 NITRO 2 (2 FLUOROPHENOXY)PYRIDINE; DRUG METABOLITE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG IDENTIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIVER MICROSOME METABOLISM; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; RAT;

ANIMALS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICROSOMES, LIVER; PYRIDINES; RATS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 0030812709     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0731-7085(97)00080-0     Document Type: Article

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