Substance P stimulates vascular endothelial cellular reducing capacity in the presence of insulin and human plasma factors

Journal of Cellular Biochemistry

Volumn 66, Issue 4, 1997, Pages 471-481

  Villablanca, Amparo C ^a   Reid, Ted W ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TEXAS TECH UNIVERSITY   (United States)

Author keywords

Cell cycle; Cell growth; Endothelial cell; Insulin; MTT; Nitric oxide; Plasma; Substance P; Tachykinin

Indexed keywords

INSULIN; SUBSTANCE P;

ANIMAL CELL; ARTICLE; CATTLE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DRUG POTENTIATION; ENDOTHELIUM CELL; GROWTH STIMULATION; HUMAN; HUMAN CELL; NONHUMAN; PLASMA FACTOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; VASCULAR ENDOTHELIUM;

ANIMALS; BLOOD PROTEINS; CATTLE; DNA; DRUG SYNERGISM; ENDOTHELIUM, VASCULAR; FORMAZANS; HUMANS; INSULIN; METHODS; OXIDATION-REDUCTION; SUBSTANCE P; TETRAZOLIUM SALTS; THYMIDINE; TRITIUM;

ANIMALIA; BOS TAURUS; TRIXIS;

EID: 0030810519     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4644(19970915)66:4<471::AID-JCB6>3.0.CO;2-I     Document Type: Article

References (48)

1. Afework M, Tomlinson A, Belai A, Burnstock G (1992): Colocalization of nitric oxide synthase and NADPH-diaphorase in rat adrenal gland. Neurochemistry 3:893-896.
2. Berridge MV, Tan AS (1992): The protein kinase C inhibitor, calphostin C, inhibits succinate-dependent mitochondrial reduction of MTT by a mechanism that does not involve protein kinase C. Biochem Biophys Res Commun 185:806-811.
3. Berridge MV, Tan AS (1993): Characterization of the cellular reduction of (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide), (MTT): Subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch Biochem Biophys 303:474-482.
4. Bossaller C, Hehlert-Friedrich C, Jost S, Rafflenbeul W, Lichtlen P (1989): Angiographic assessment of human coronary artery endothelial function by measurement of endothelium-dependent vasodilation. Eur Heart J 10:44-48.
5. Burdon RH, Gill V, Rice-Evans C (1993): Reduction of a tetrazolium salt and superoxide generation in human tumor cells (HeLa). Free Radic Res Commun 18:369-380.
6. Christie M, Griffith R, Lewis M (1989): A comparison of basal and agonist-stimulated release of endothelium-derived relaxing factor from different arteries. Br J Pharmacol 98:397-406.
7. Flock A, Massa N, Thiry C, Cavero I (1993): Evidence for NK-1 receptor subtypes from in vivo bronchopulmonary and cardiovascular studies. Regul Pept 46:307-308.
8. Fong TM, Anderson SA, Yu H, Huang RC, Strader CD (1991): Differential activation of intracellular effector by two isoforms of human neurokinin-1 receptor. Mol Pharmacol 41:24-30.
9. Furness J, Papka RE, Della NG, Costa M, Eskay RL (1982): Substance P-like immunoreactivity in nerves associated with the vascular system of guinea-pigs. Neuroscience 7:447-459.
10. Gauntt CD, Ohira A, Honda O, Kigasawa K, Kujimoto T, Masutani H, Yodoi J, Honda Y (1994): Mitochondrial induction of adult T cell leukemia derived factor (ADF/ hTx) after oxidative stresses in retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 35:2916-2923.
11. Geng Y, Hansson GK, Holme E (1992): Interferon-gamma and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells. Circ Res 71:1268-1276.
12. Hansen M, Nielsen S, Berg K (1989): Re-examination and further development of a precise and rapid dye method of measuring cell growth/kill. J Immunol Methods 119:203-210.
13. Hirata Y, Takagi Y, Takata D, Fukuda Y, Yoshimi H, Fujita T (1988): Calcitonin gene-related peptide receptor in cultured vascular smooth muscle and endothelial cells. Biochem Biophys Res Commun 151:1113-1121.
14. Hope BT, Michael GJ, Knigge KM, Vincent SR (1991): Neuronal NADPH diaphorase is a nitric oxide synthase. Proc Natl Acad Sci USA 88:2811-2814.
15. Huet O, Petit JM, Ratinaud MH, Julien R (1992): NADH-dependent dehydrogenase activity estimation of flow cytometric analysis of (3-[4,5-dimethylthiazolyl-2-yl]-2,5-diphenyltetrazolium bromide), (MTT) reduction. Cytometry 13:532-539.
16. Irani K, Xia Y, Zweier JL, Sollott SJ, Der CJ, Fearon ER, Sundaresan M, Finkel T, Goldschmidt-Clermont PJ (1997): Mitogenic signaling mediated by oxidants in rastransformed fibroblasts. Science 275:1649-1652.
17. Jiang T, Grant RL, Acosta D (1993): A digitized fluorescence imaging study of intracellular free calcium, mitochondrial integrity and cytotoxicity in rat renal cells exposed to ionomycin, a calcium ionophore. Toxicology 85:41-65.
18. Linnik M, Moskowitz M (1989): Identification of immunoreactive substance P in human and other mammalian endothelial cells. Peptides 10:957-962.
19. Loesch A, Burnstock G (1988): Ultrastructural localization of serotonin and substance P in vascular endothelial cells of rat femoral and mesenteric arteries. Anat Embryol (Berl) 178:137-142.
20. Loveland BE, Johns TG, Mackay IR, Vaillant F, Wang ZX, Hertzog PJ (1992): Validation of the MTT dye assay for enumeration of cells in proliferative and antiproliferative assays. Biochem Int 27:501-510.
21. Marceau F, Tremblay B, Couture R, Regoli D (1989): Prostacyclin release induced by neurokinins in cultured human endothelial cells. Can J Physiol Pharmacol 67:159-162.
22. Mathews CK, VanHolde KE (1990): "Biochemistry." Redwood City, CA: WA Benjamin/Cummings.
23. Matis W, Lavker R, Murphy G (1990): Substance P induces the expression of an endothelial-leukocyte adhesion molecule by microvascular endothelium. J Invest Dermatol 94:492-495.
24. Mosmann T (1983): Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 65:55-63.
25. Musser DA, Oseroff AR (1994): The use of tetrazolium salts to determine sites of damage to the mitochondrial electron transport chain in intact cells following in vitro photodynamic therapy with Photofrin II. Photochem Photobiol 59:621-626.
26. Nakamura Y, Parent R, Lavellee M (1990): The effects of substance P (SP) on epicardial coronary diameter (CD) and coronary blood flow (CBF) were examined in conscious dogs. Am J Physiol 258(2 pt. 2):H565-H573.
27. Nguyen LS, Villablanca AC, Rutledge JC (1995): Substance P increases microvascular permeability via nitric oxide-mediated convective pathways. Am J Physiol 268:R1060-R1068.
28. Nilsson J, von Euler A, Dalsgaard C (1985): Stimulation of connective tissue growth by substance P and substance K. Nature 315:61-63.
29. Obolenskaya M, Schulze-Specking A, Plaumann B, Frenzer K, Freudenberg N, Decker K (1994): Nitric oxide production by cells isolated from regenerating rat liver. Biochem Biophys Res Commun 204:1305-1311.
30. Okajima T, Nakamura K, Zhang H, Ling N, Tanabe T, Yasuda T, Rosenfeld RG (1992): Sensitive colorimetric bioassays for insulin-like growth factor (IGF) stimulation of cell proliferation and glucose consumption: Use in studies of IGF analogs. Endocrinology 130:2201-2212.
31. Pagliacci MC, Spinozzi F, Migliorati G, Fumi G, Smacchia M, Grignani F, Riccardi C, Nicoletti I (1993): Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: A further pitfall in the use of the MTT assay for evaluating cell growth and survival. Eur J Cancer 29A:1573-1577.
32. Palmer RJM, Ashton DS, Moncada S (1988): Vascular endothelial cells synthesize nitric oxide from L-arginine. Nature 333:664-666.
33. Payan D (1985): Receptor-mediated mitogenic effects of substance P on cultured smooth muscle cells. Biochem Biophys Res Commun 130:104-109.
34. Pledger W, Stiles C, Antoniades H, Schier C (1977): Induction of DNA synthesis in Balb/c3T3 cells by serum components: Re-evaluation of the commitment process. Proc Natl Acad Sci USA 74:4481-4485.
35. Powell D, Skrabanek P, Cannon D, Balfe A (1980): Substance P in human plasma. In Marsan CA, Tracysk WX (eds): "Neuropeptides and Neural Transmission." IBRO Monography Series. New York: Raven Press, pp 105-110.
36. Ralevic V, Milner P, Hudlick O, Kristek F, Burnstock G (1990): Substance P is released from the endothelium of normal and capsaicin-treated rat hind-limb vasculature, in vivo, by increased flow. Circ Res 66:1178-1183.
37. Ross R (1986): Pathogenesis of atherosclerosis - An update. N Engl J Med 314:488-500.
38. Shimizu T, Fujita S, Izumi K, Kojar T, Ohba N, Fukuda T (1984): Corneal lesions induced by the systemic administration of capsaicin in neonatal mice and rats. Naunyn-Schmiedebergs Arch Pharmacol 326:347-351.
39. Skrabanek P, Cannon D, Kirrane J, Legge D, Powell D (1976): Circulating immunoreactive substance P in man. Isr J Med Sci 145:399-408.
40. Stamler JS, Jaraki O, Osborne J, Simon DI, Keaney J, Vita J, Singel D, Valeri CR, Loscalzo J (1992): Nitric oxide circulates in mammalian plasma primarily as a S-nitroso adduct of serum albumin. Proc Natl Acad Sci USA 89: 7674-7677.
41. Sung YJ, Dietert RR (1994): Nitric oxide (NO)-induced mitochondrial injury among chicken NO-generating and target leukocytes. J Leukocyte Biol 56:52-58.
42. Takagi K, Isobe Y, Yasukawa K, Okouchi E, Suketa Y (1994): Nitric oxide blocks the cell cycle of mouse macrophage-like cells in the early G2 + M phase. FEBS Lett 340:159-162.
43. Villablanca AC, Murphy CJ, Reid TW (1994): Growth-promoting effects of substance P on endothelial cells in vitro: Synergism with CGRP, insulin, and plasma factors. Circ Res 75:1113-1120.
44. Weichert H, Blechschmidt I, Schroder S, Ambrosius H (1991): The MTT assay as a rapid test for cell proliferation and cell killing: Application to human peripheral blood lymphocytes (PBL). Allergy Immunol (Lpz) 37(3-4): 139-144.
45. Woll P, Rozengurt E (1989): Neuropeptides as growth regulators. Br Med Bull 45:492-505.
46. Zeng G, Quon MJ (1996): Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. J Clin Invest 98:894-898.
47. Ziehe M, Morbidelli L, Pacini M, Geppetti P, Alessandri G, Maggi C (1990): Substance P stimulates neovascularization in vivo and proliferation of cultured endothelial cells. Microvasc Res 40:264-278.
48. Ziehe M, Morbidelli L, Macini E, Amerini S, Granger H, Maggi C, Geppetti P, Ledda F (1994): Nitric oxide mediates angiogenesis in vivo and endothelial cell growth and migration in vitro promoted by substance P. J Clin Invest 94:2036-2044.