β2-Adrenoceptor activation by zinterol causes protein phosphorylation, contractile effects and relaxant effects through a cAMP pathway in human atrium

Molecular and Cellular Biochemistry

Volumn 163-164, Issue , 1996, Pages 113-123

  Kaumann, Alberto J ^a   Sanders, Louise ^a   Lynham, James A ^a   Bartel, Sabine ^b   Kuschel, Meike ^b   Karczewski, Peter ^b   Krause, Ernst Georg ^b  

^a BABRAHAM INSTITUTE   (United Kingdom)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

Author keywords

Adenylyl cyclase stimulation; Atrial relaxation and contraction; C protein; Human atrium; Phospholamban; Protein phosphorylation; Receptor binding; Troponin I; Zinterol; 2 adrenoceptors

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; CYANOPINDOLOL; CYCLIC AMP; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); ISOPRENALINE; PHOSPHOLAMBAN; PROTEIN C; TROPONIN I; ZINTEROL;

ARTICLE; BINDING AFFINITY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG RECEPTOR BINDING; ENZYME ACTIVATION; HEART ATRIUM; HEART CONTRACTION; HEART FAILURE; HEART MUSCLE RELAXATION; HUMAN TISSUE; INOTROPISM; ISOLATED HEART; ISOTOPE LABELING; MALE; NONHUMAN; OPEN HEART SURGERY; PROTEIN PHOSPHORYLATION;

ADENOSINE TRIPHOSPHATASES; ADENYLATE CYCLASE; ADRENERGIC BETA-AGONISTS; ANIMALS; CALCIUM-BINDING PROTEINS; CARRIER PROTEINS; CATS; CYCLIC AMP; DOGS; ETHANOLAMINES; HEART ATRIA; HUMANS; ISOPROTERENOL; MUSCLE RELAXATION; MYOCARDIAL CONTRACTION; PHOSPHORYLATION; RATS; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; STIMULATION, CHEMICAL; TROPONIN I;

CANIS FAMILIARIS; FELIS CATUS; OVIS ARIES;

EID: 0029731081     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00408647     Document Type: Article

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