-
1
-
-
45449097286
-
-
Reviews of inverse electron demand Diels-Alder reactions: (a)
-
Reviews of inverse electron demand Diels-Alder reactions: (a) Boger, D.L. Tetrahedron 1983, 39, 2869 - 2939.
-
(1983)
Tetrahedron
, vol.39
, pp. 2869-2939
-
-
Boger, D.L.1
-
2
-
-
33845376451
-
-
(b)
-
(b) Boger, D.L. Chem. Rev. 1986, 86, 781 - 793.
-
(1986)
Chem. Rev.
, vol.86
, pp. 781-793
-
-
Boger, D.L.1
-
3
-
-
0003719612
-
-
(c) Wasserman, H. H., Ed; Academic: New York, Chapters 9 and 10
-
(c) Boger, D.L.; Weinreb, S.N. Hetero Diels-Alder Methodology in Organic Synthesis; Organic Chemistry Monograph Series, Vol. 47; Wasserman, H. H., Ed; Academic: New York, 1987; Chapters 9 and 10.
-
(1987)
Hetero Diels-Alder Methodology in Organic Synthesis; Organic Chemistry Monograph Series
, vol.47
-
-
Boger, D.L.1
Weinreb, S.N.2
-
4
-
-
0030586204
-
-
and literature cited therein (ref. 1).
-
Benson, S.C.; Lee, L.; Snyder, J.K. Tetrahedron Lett. 1996, 37, 5061 - 5064, and literature cited therein (ref. 1).
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 5061-5064
-
-
Benson, S.C.1
Lee, L.2
Snyder, J.K.3
-
5
-
-
0029825205
-
-
For some recent lead references on 3-deazapurines and their biological activity: (a)
-
For some recent lead references on 3-deazapurines and their biological activity: (a) Impagnatiello, A.; Franceschini, N.; Oratore, A.; Bozzi, A. Biochimie 1996, 78, 267 - 272.
-
(1996)
Biochimie
, vol.78
, pp. 267-272
-
-
Impagnatiello, A.1
Franceschini, N.2
Oratore, A.3
Bozzi, A.4
-
6
-
-
0029931864
-
-
(b)
-
(b) Minakawa, N.; Sasbuchi, Y.; Kiyosue, A.; Kojima, N.; Matsuda, A. Chem. Pharm. Bull. 1996, 44, 288 - 295.
-
(1996)
Chem. Pharm. Bull.
, vol.44
, pp. 288-295
-
-
Minakawa, N.1
Sasbuchi, Y.2
Kiyosue, A.3
Kojima, N.4
Matsuda, A.5
-
7
-
-
0030070680
-
-
(c)
-
(c) Carceller, E.; Merlos, M.; Giral, M.; Balsa, D.; Garcia-Rafanell, J.; Forn, J. J. Med. Chem. 1996, 39, 487 - 493.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 487-493
-
-
Carceller, E.1
Merlos, M.2
Giral, M.3
Balsa, D.4
Garcia-Rafanell, J.5
Forn, J.6
-
8
-
-
0029894001
-
-
(d)
-
(d) Shuto, S.; Obara, T.; Saito, Y.; Andrei, G.; Snoeck, R.; De Clerq, E.; Matsuda, A. J. Med. Chem. 1996, 39, 2392 - 2399.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 2392-2399
-
-
Shuto, S.1
Obara, T.2
Saito, Y.3
Andrei, G.4
Snoeck, R.5
De Clerq, E.6
Matsuda, A.7
-
9
-
-
0030426717
-
-
(e)
-
(e) Endresen, P.C.; Loennechen, T.; Kildalsen, H.; Aarbakke, J. J. Pharm. Exp. Ther. 1996, 278, 1318 - 1324.
-
(1996)
J. Pharm. Exp. Ther.
, vol.278
, pp. 1318-1324
-
-
Endresen, P.C.1
Loennechen, T.2
Kildalsen, H.3
Aarbakke, J.4
-
10
-
-
0028882786
-
-
(f)
-
(f) Mederski, W.W.K.R.; Dorsch, D.; Osswald, M.; Beier, N.; Lues, I.; Minck, K.-O.; Schelling, P.; Ladstetter, B. J. Bioorg. Med. Chem. Lett. 1995, 5, 2665 - 2670.
-
(1995)
J. Bioorg. Med. Chem. Lett.
, vol.5
, pp. 2665-2670
-
-
Mederski, W.W.K.R.1
Dorsch, D.2
Osswald, M.3
Beier, N.4
Lues, I.5
Minck, K.-O.6
Schelling, P.7
Ladstetter, B.8
-
11
-
-
0023409608
-
-
Isolation and bioactivity of the grossularines: (a)
-
Isolation and bioactivity of the grossularines: (a) Helbecque, N.; Moquin, C.; Bernier, J.-L.; Morel, E.; Guyot, M.; Henichart, J.-P. Cancer Biochem. Biophys. 1987, 9, 271 - 279.
-
(1987)
Cancer Biochem. Biophys.
, vol.9
, pp. 271-279
-
-
Helbecque, N.1
Moquin, C.2
Bernier, J.-L.3
Morel, E.4
Guyot, M.5
Henichart, J.-P.6
-
13
-
-
15844431131
-
-
(c)
-
(c) Abas, S.A.; Hossain, M.B.; van der Helm, D.; Schmitz, F.J.; Laney, M.; Cabuslay, R.; Shatzman, R.C. J. Org. Chem. 1996, 61, 2709 - 2712.
-
(1996)
J. Org. Chem.
, vol.61
, pp. 2709-2712
-
-
Abas, S.A.1
Hossain, M.B.2
Van Der Helm, D.3
Schmitz, F.J.4
Laney, M.5
Cabuslay, R.6
Shatzman, R.C.7
-
14
-
-
0027406260
-
-
Syntheses and synthetic studies: (d)
-
Syntheses and synthetic studies: (d) Achab, S.; Guyot, M.; Potier, P. Tetrahedron Lett. 1993, 34, 2127 - 2130.
-
(1993)
Tetrahedron Lett.
, vol.34
, pp. 2127-2130
-
-
Achab, S.1
Guyot, M.2
Potier, P.3
-
15
-
-
0029162015
-
-
(e) and references therein
-
(e) Chosh T.; Yamada, S.; Sugino, E.; Kawada, T.; Hibino, S. J. Org. Chem. 1995, 60, 5899 - 5904, and references therein.
-
(1995)
J. Org. Chem.
, vol.60
, pp. 5899-5904
-
-
Chosh, T.1
Yamada, S.2
Sugino, E.3
Kawada, T.4
Hibino, S.5
-
17
-
-
0000181175
-
-
(b)
-
(b) Seitz, G.; Hoferichter, R.; Mohr, R. Arch. Pharm. (Weinheim) 1989, 322, 415 - 417.
-
(1989)
Arch. Pharm. (Weinheim)
, vol.322
, pp. 415-417
-
-
Seitz, G.1
Hoferichter, R.2
Mohr, R.3
-
18
-
-
0027383974
-
-
(a)
-
(a) Xu, Y.-Z.; Yakushijin, K.; Horne, D.A. Tetrahedron Lett. 1993, 34, 6981 - 6984.
-
(1993)
Tetrahedron Lett.
, vol.34
, pp. 6981-6984
-
-
Xu, Y.-Z.1
Yakushijin, K.2
Horne, D.A.3
-
19
-
-
0343967019
-
-
Horne has also reported a [4+6]-condensation of 4-alkyl-2-aminoimidazoles: (b)
-
Horne has also reported a [4+6]-condensation of 4-alkyl-2-aminoimidazoles: (b) Xu, Y.-Z.; Yakushijin, K.; Horne, D.A. J. Org. Chem. 1997, 60, 9569 - 9571.
-
(1997)
J. Org. Chem.
, vol.60
, pp. 9569-9571
-
-
Xu, Y.-Z.1
Yakushijin, K.2
Horne, D.A.3
-
27
-
-
37049141101
-
-
Similar rearrangements are known in the cycloaddition chemistry of indoles: (a)
-
Similar rearrangements are known in the cycloaddition chemistry of indoles: (a) Acheson, R.M.; Bridson, J.N.; Cecil, T.R.; Hands, A.R. J. Chem. Soc., Perk. Trans. I 1972, 1569 - 1576.
-
(1972)
J. Chem. Soc., Perk. Trans.
, vol.1
, pp. 1569-1576
-
-
Acheson, R.M.1
Bridson, J.N.2
Cecil, T.R.3
Hands, A.R.4
-
29
-
-
0001101712
-
-
(c)
-
(c) Benson, S.C.; Palabrica, C.A.; Snyder, J.K. J. Org. Chem. 1987, 52, 4610 - 4614.
-
(1987)
J. Org. Chem.
, vol.52
, pp. 4610-4614
-
-
Benson, S.C.1
Palabrica, C.A.2
Snyder, J.K.3
-
30
-
-
0001206433
-
-
(d)
-
(d) Benson, S.C.; Gross, J.L.; Snyder, J.K. 1990, 55, 3257 - 3269.
-
(1990)
, vol.55
, pp. 3257-3269
-
-
Benson, S.C.1
Gross, J.L.2
Snyder, J.K.3
-
31
-
-
0342660884
-
-
For a recent review of pyridopyrimidines Taylor, E.C., Ed.; John Wiley & Sons: New York, Fused Pyrimidines; Miscellaneous Fused Pyrimidines, Chapter 1
-
For a recent review of pyridopyrimidines: Warner, J.C. In The Chemistry of Heterocyclic Compounds; Taylor, E.C., Ed.; John Wiley & Sons: New York, 1992; Vol. 24, Part 4: Fused Pyrimidines; Miscellaneous Fused Pyrimidines, Chapter 1.
-
(1992)
In the Chemistry of Heterocyclic Compounds
, vol.24
, Issue.PART 4
-
-
Warner, J.C.1
-
34
-
-
84971036262
-
-
(b)
-
(b) Elix, J.A.; Wilson, W.S.; Warrener, R.N.; Calder, I.C. Aust. J. Chem. 1972, 25, 865 - 874.
-
(1972)
Aust. J. Chem.
, vol.25
, pp. 865-874
-
-
Elix, J.A.1
Wilson, W.S.2
Warrener, R.N.3
Calder, I.C.4
-
35
-
-
0343095200
-
-
For the preparation of 2d, see ref. 10d; 2d had appeared in the literature prior to this, but without accompanying details for its preparation or characterization: (a)
-
For the preparation of 2d, see ref. 10d; 2d had appeared in the literature prior to this, but without accompanying details for its preparation or characterization: (a) Neunhoeffer, H.; Fruhauf, H.W. Tetrahedron Lett. 1970, 3355 - 3356.
-
(1970)
Tetrahedron Lett.
, pp. 3355-3356
-
-
Neunhoeffer, H.1
Fruhauf, H.W.2
-
36
-
-
49649138064
-
-
(b)
-
(b) Burg, B.; Dittmar, W.; Reim, H.; Steigel, A.; Sauer, J. Tetrahedron Lett. 1975, 2897 - 2890.
-
(1975)
Tetrahedron Lett.
, pp. 2897-2890
-
-
Burg, B.1
Dittmar, W.2
Reim, H.3
Steigel, A.4
Sauer, J.5
-
37
-
-
0343095199
-
-
(c)
-
(c) Reim, H.; Steigel, A.; Sauer, J. Tetrahedron Lett. 1975, 2901 - 2904. For reviews of 1,2,4-triazine preparation:
-
(1975)
Tetrahedron Lett.
, pp. 2901-2904
-
-
Reim, H.1
Steigel, A.2
Sauer, J.3
-
38
-
-
0003600435
-
-
For reviews of 1,2,4-triazine preparation: (d) Wiley-Interscience: New York
-
(d) Neunhoeffer, H. Chemistry of 1,2,3-Triazines and 1,2,4-Triazines, Tetrazines, and Pentazines; The Chemistry of Heterocyclic Compounds Monograph Series, Vol. 33; Wiley-Interscience: New York, 1978; pp 189 - 574.
-
(1978)
Chemistry of 1,2,3-Triazines and 1,2,4-Triazines, Tetrazines, and Pentazines; the Chemistry of Heterocyclic Compounds Monograph Series
, vol.33
, pp. 189-574
-
-
Neunhoeffer, H.1
-
39
-
-
84944078040
-
-
(e) Boulton, A.J., McKillop, A., Eds.; Pergamon: Oxford
-
(e) Neunhoeffer, H. In Comprehensive Heterocyclic Chemistry; Boulton, A.J., McKillop, A., Eds.; Pergamon: Oxford, 1984; Vol. 3, pp 385 - 456.
-
(1984)
In Comprehensive Heterocyclic Chemistry
, vol.3
, pp. 385-456
-
-
Neunhoeffer, H.1
-
40
-
-
0001639324
-
-
A rearrangement mechanism involving tautomerization of 3,4-dihydropyridine intermediate A (Scheme 2) to the more stable 1,4-dihydropyridine is also conceivable. (a)
-
A rearrangement mechanism involving tautomerization of 3,4-dihydropyridine intermediate A (Scheme 2) to the more stable 1,4-dihydropyridine is also conceivable. (a) Bodor, N.; Pearlman, R. J. Am. Chem. Soc. 1978, 100, 4946 - 4953.
-
(1978)
J. Am. Chem. Soc.
, vol.100
, pp. 4946-4953
-
-
Bodor, N.1
Pearlman, R.2
-
42
-
-
0343966989
-
-
(c) Such a tautomerization has been invoked by Seitz for the analogous rearrangement of the indole cycloadduct, ref. 10b
-
(c) Bohm, S.; Kuthan, J. Coll. Czech. Chem. Commun. 1982, 47, 2735 - 2745. Such a tautomerization has been invoked by Seitz for the analogous rearrangement of the indole cycloadduct, ref. 10b.
-
(1982)
Coll. Czech. Chem. Commun.
, vol.47
, pp. 2735-2745
-
-
Bohm, S.1
Kuthan, J.2
-
43
-
-
0029975029
-
-
For lead references to the 8-deazapteridines and their biological applications: (a)
-
For lead references to the 8-deazapteridines and their biological applications: (a) Rewcastle, G.W.; Palmer, B.D.; Thompson, A.M.; Bridges, A.J.; Cody, D.R.; Zhou, H.; Fry, D.W.; McMichael, A.; Denny, W.A. J. Med. Chem. 1996, 39, 1823 - 1835.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1823-1835
-
-
Rewcastle, G.W.1
Palmer, B.D.2
Thompson, A.M.3
Bridges, A.J.4
Cody, D.R.5
Zhou, H.6
Fry, D.W.7
McMichael, A.8
Denny, W.A.9
-
44
-
-
0029881975
-
-
(b)
-
(b) Gangjee, A.; Zhu, Y.; Queener, S.F.; Francorn, P.; Broom, A.D. J. Med. Chem. 1996, 39, 1836 - 1845.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 1836-1845
-
-
Gangjee, A.1
Zhu, Y.2
Queener, S.F.3
Francorn, P.4
Broom, A.D.5
|