Effects of crystallization in the presence of the opposite enantiomer on the crystal properties of (SS)-( + )-pseudoephedrinium salicylate

International Journal of Pharmaceutics

Volumn 127, Issue 1, 1996, Pages 53-63

  Duddu, Sarma P ^a,b   Fung, Flora K Y ^a   Grant, David J W ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

(SS) ( + ) Pseudoephedrinium salicylate; Chiral; Crystallization; Disruption index; Enantiomeric impurity; Enthalpy of fusion; Enthalpy of solution; Entropy of fusion; Entropy of solution; Intrinsic dissolution rate; Segregation coefficient

Indexed keywords

PSEUDOEPHEDRINE; PSEUDOEPHEDRINE SALICYLATE; SALICYLATE SODIUM; UNCLASSIFIED DRUG;

ARTICLE; CALORIMETRY; CRYSTALLIZATION; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG IMPURITY; DRUG RELEASE; ENANTIOMER; ENTHALPY; ENTROPY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; TEMPERATURE;

EID: 0030030510     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/0378-5173(95)04117-6     Document Type: Article

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