The cholesterol-raising diterpenes from coffee beans increase serum lipid transfer protein activity levels in humans

Atherosclerosis

Volumn 132, Issue 2, 1997, Pages 251-254

  Van Tol, Arie ^a   Urgert, Rob ^b   De Jong Caesar, Ruth ^a   Van Gent, Teus ^a   Scheek, Leo M ^a   De Roos, Baukje ^b   Katan, Martijn B ^b  

^a ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Cafestol; CETP; Coffee; Diterpenes; Kahweol; LCAT; Lipid transfer proteins; PLTP

Indexed keywords

DITERPENE; LIPID TRANSFER PROTEIN; LIPOPROTEIN; NATURAL PRODUCT; PHOSPHATIDYLCHOLINE STEROL ACYLTRANSFERASE; PHOSPHOLIPID TRANSFER PROTEIN;

ADULT; ARTICLE; ATHEROSCLEROSIS; CLINICAL ARTICLE; CLINICAL TRIAL; COFFEE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; HUMAN; LIPOPROTEIN BLOOD LEVEL; LIPOPROTEIN METABOLISM; MALE; PLANT SEED; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ADULT; CARRIER PROTEINS; COFFEE; DITERPENES; HUMANS; LIPOPROTEINS, HDL; LIPOPROTEINS, LDL; LIPOPROTEINS, VLDL; MALE;

EID: 0030805711     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(97)00099-3     Document Type: Article

References (21)

1. Thelle DS, Arnesen E, Förde OH. The Tromsö Heart Study. Does coffee raise serum cholesterol?. N Engl J Med 1983;308:1454-7.
2. Weusten-van der Wouw MPME, Katan MB, Viani R, et al. Identity of the cholesterol-raising factor from boiled coffee and its effects on liver function enzymes. J Lipid Res 1994;35:721-33.
3. Heckers H, Gobel U, Kleppel U. End of the coffee mystery: diterpene alcohols raise serum low-density lipoprotein cholesterol and triglyceride levels. J Intern Med 1994;235:192-3.
4. Urgert R, Van der Weg G, Kosmeijer-Schuil TG, Van de Bovenkamp P, Hovenier R, Katan MB. Levels of the cholesterol-elevating diterpenes cafestol and kahweol in various coffee beans. J Agric Food Chem 1995;43:2167-72.
5. Zock PL, Katan MB, Merkus MP, Van Dusseldorp M, Harryvan JL. Effect of a lipid-rich fraction from boiled coffee on serum cholesterol. Lancet 1990;335:1235-7.
6. Mensink RP, Lebbink WJ, Lobbezoo IE, Weusten-van der Wouw MPME, Zock PL, Katan MB. Diterpene composition of oils from Arabica and Robusta coffee beans and their effects on serum lipids in man. J Intern Med 1995;237:543-50.
7. Van Rooij J, Van der Stegen GHD, Schoemaker RC, et al. A placebo-controlled parallel study of the effect of two types of coffee oil on serum lipids and transaminases: identification of chemical substances involved in the cholesterol-raising effect of coffee. Am J Clin Nutr 1995;61:1277-83.
8. Grundy SM. Cholesterol-raising effects of coffee: clues to regulation of cholesterol metabolism. J Intern Med 1995;238:475-7.
9. Tall AR. Plasma cholesteryl ester transfer protein. J Lipid Res 1993;34:1255-74.
10. Tollefson JH, Ravnik S, Albers JJ. Isolation and characterization of a phospholipid transfer protein [LTP-II] from human plasma. J Lipid Res 1988;29:1593-602.
11. Jauhiainen M, Metso J, Pahlman R, Blomqvist S, Van Tol A, Ehnholm C. Human plasma phospholipid transfer protein causes high density lipoprotein conversion. J Biol Chem 1993;268:4032-6.
12. Groener JEM, Pelton RW, Kostner GM. Improved estimation of cholesteryl ester transfer/exchange activity in serum or plasma. Clin Chem 1986;32:283-6.
13. Speijer H, Groener JE, van Ramshorst E, Van Tol A. Different locations of cholesteryl ester transfer protein and phospholipid transfer protein activities in plasma. Atherosclerosis 1991;90:159-68.
14. Hannuksela M, Marcel YL, Kesaniemi YA, Savolainen MJ. Reduction in the concentration and activity of plasma cholesteryl ester transfer protein by alcohol. J Lipid Res 1992;33:737-44.
15. Glomset JA, Wright JL. Some properties of a cholesterol esterifying enzyme in human plasma. Biochim Biophys Acta 1964;89:266-7.
16. Urgert R, Essed N, van der Weg G, Kosmeijer-Schuil TG, Katan MB. Separate effects of the coffee diterpenes cafestol and kahweol on serum lipids and liver aminotransferases. Am J Clin Nutr 1997;65:519-24.
17. Groener JEM, Van Gent T, Van Tol A. Effect of lipid transfer protein on plasma lipids, apolipoproteins and metabolism of high-density lipoprotein cholesteryl ester in the rat. Biochim Biophys Acta 1989;1002:93-100.
18. Masucci-Magoulas L, Plump A, Jiang XC, Walsh A, Breslow JL, Tall AR. Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice-A novel mechanism signals changes in plasma cholesterol levels. J Clin Invest 1996;97:154-61.
19. Albers JJ, Wolfbauer G, Cheung MC, et al. Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies. Biochim Biophys Acta 1995;1258:27-34.
20. Jiang X-C, Bruce C. Regulation of murine plasma phospholipid transfer protein activity and mRNA levels by lipopolysaccharide and high cholesterol diet. J Biol Chem 1995;270:17133-8.
21. Jiang X-C, Agellon LB, Walsh A, Breslow JL, Tall AR. Dietary cholesterol increases transcription of the human cholesteryl ester transfer protein gene in transgenic mice. Dependence on natural flanking sequences. J Clin Invest 1992;90:1290-5.