Profound induction of hepatic cholesteryl ester transfer protein transgene expression in apolipoprotein E and low density lipoprotein receptor gene knockout mice. A novel mechanism signals changes in plasma cholesterol levels

Journal of Clinical Investigation

Volumn 97, Issue 1, 1996, Pages 154-161

  Masucci Magoulas, Lori ^a   Plump, Andrew ^b   Jiang, Xian Cheng ^a   Walsh, Annemarie ^b   Breslow, Jan L ^b   Tall, Alan R ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

CETP; Hydroxymethyl CoA reductase; Hypercholesterolemia; LDL receptor; Transgenic mouse

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CONTROLLED STUDY; DNA FLANKING REGION; GENE INDUCTION; HYPERCHOLESTEROLEMIA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE;

ANIMALS; APOLIPOPROTEINS E; CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL ESTERS; CHOLESTEROL, DIETARY; CROSSES, GENETIC; GENE EXPRESSION REGULATION; GLYCOPROTEINS; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; HYPERCHOLESTEROLEMIA; LIPOPROTEINS; LIVER; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; RECEPTORS, LDL; RNA, MESSENGER; TRANSGENES;

EID: 0030058858     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI118384     Document Type: Article

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