The human glycinamide ribonucleotide transformylase domain: Purification, characterization, and kinetic mechanism

Archives of Biochemistry and Biophysics

Volumn 341, Issue 1, 1997, Pages 98-103

  Caperelli, Carol A ^a   Giroux, Eugene L ^a  

^a UNIVERSITY OF CINCINNATI MEDICAL CENTER   (United States)

Author keywords

folate enzyme; human; purine biosynthesis

Indexed keywords

PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CHEMOTHERAPY; CARBOXY TERMINAL SEQUENCE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME KINETICS; ENZYME MECHANISM; ENZYME PURIFICATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PURINE SYNTHESIS; TARGET CELL;

ESCHERICHIA COLI; EUKARYOTA; MAMMALIA;

EID: 0031149529     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1997.9947     Document Type: Article

References (32)

1. Warren L., Buchanan J. M. J. Biol. Chem. 229:1957;613-625.
2. Beardsley G. P., Taylor E. C., Moroson B. A., Moran R. G. J. Biol. Chem. 264:1989;328-333.
3. Moran R. G., Baldwin S. W., Taylor E. C., Shih C. J. Biol. Chem. 264:1989;21047-21051.
4. Aimi J., Qiu H., Williams J., Zalkin H., Dixon J. E. Nucleic Acids Res. 18:1990;6665-6672.
5. Schild D., Brake A. J., Kiefer M. C., Young D., Barr P. J. Proc. Natl. Acad. Sci. USA. 87:1990;2916-2920.
6. Smith J. M., Daum H. A. III. J. Biol. Chem. 262:1987;10565-10569.
7. Inglese J., Johnson D. L., Shiau A., Smith J. M., Benkovic S. J. Biochemistry. 29:1990;1436-1443.
8. White J. H., Lusnak K., Fogel S. Nature. 315:1985;350-352.
9. Ebbole D. J., Zalkin H. J. Biol. Chem. 262:1987;8274-8287.
10. Kan C.-C., Gehring M. R., Nodes B. R., Janson C. A., Almassy R. J., Hostomska Z. J. Protein Chem. 11:1992;467-473.
11. Studier F. W., Rosenberg A. H., Dunn J. J., Durbendorff A. Methods Enzymol. 185:1991;60-89.
12. Chettur G., Benkovic S. J. Carbohydr. Res. 56:1977;75-86.
13. Schendel F. J., Stubbe J. Biochemistry. 25:1986;2256-2264.
14. Ames B. N., Dubin D. T. J. Biol. Chem. 235:1960;769-775.
15. Caperelli C. A., Conigliaro J. J. Med. Chem. 29:1986;2117-2119.
16. Smith G. K., Mueller W. T., Benkovic P. A., Benkovic S. J. Biochemistry. 20:1981;1241-1245.
17. Sambrook J., Fritsch E. F., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
18. Caperelli C. A. Biochemistry. 24:1985;1316-1320.
19. Nilsson K., Norrlow O., Mosbach K. Acta Chem. Scand. B. 35:1981;19-27.
20. Krchnak V., Vagner J., Safar P., Lebl M. Collect. Czech. Chem. Commun. 53:1988;2542-2548.
21. Caperelli C. A. J. Biol. Chem. 264:1989;5053-5057.
22. Bradford M. Anal. Biochem. 72:1976;248-254.
23. Laemmli U. K. Nature. 227:1970;680-685.
24. Cleland W. W. Methods Enzymol. 63:1979;103-138.
25. Gouy M., Gautier C. Nucleic Acids Res. 10:1982;7055-7074.
26. Young M., Sammons R. D., Mueller W. T., Benkovic S. J. Biochemistry. 23:1984;3979-3986.
27. Hirel P. H., Schmitter J. M., Dessen P., Fayat G., Blanquet S. Proc. Natl. Acad. Sci. USA. 86:1989;8247-8251.
28. Fromm H. J. Methods Enzymol. 63:1979;467-486.
29. Dalziel K. Acta Chem. Scand. 11:1957;1706-1723.
30. Antle V. D., Liu D., McKellar B. R., Caperelli C. A., Hua M., Vince R. J. Biol. Chem. 271:1996;8192-8195.
31. Antle V. D., Liu D., McKellar B. R., Caperelli C. A., Hua M., Vince R. J. Biol. Chem. 271:1996;6045-6049.
32. Baldwin S. W., Tse A., Gossett L. S., Taylor E. C., Rosowsky A., Shih C., Moran R. G. Biochemistry. 30:1991;1997-2006.