Single-stranded conformational polymorphism analysis of the mitochondrial glycerol phosphate dehydrogenase gene in NIDDM

Diabetes

Volumn 46, Issue 10, 1997, Pages 1660-1661

  MacDonald, Michael J ^a,d   Brown, Laura J ^a   Hasan, Noaman M ^a   Stoffel, Markus ^b   Dills, Diana G ^c  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d Medical Science   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCEROL 3 PHOSPHATE DEHYDROGENASE;

ARTICLE; DISEASE CLASSIFICATION; DISEASE SEVERITY; GENE EXPRESSION; GENE MUTATION; GENETIC ANALYSIS; HUMAN; MASS SCREENING; MITOCHONDRIAL MEMBRANE; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; SINGLE STRAND CONFORMATION POLYMORPHISM;

EID: 0030802679     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diacare.46.10.1660     Document Type: Article

References (9)

1. MacDonald MJ, Efendic S, Ostenson C-G: Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rat. Diabetes 45:886-890, 1996
2. MacDonald MJ, Tang J, Polonsky KS: Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats. Diabetes 45:1626-1630, 1996
3. Hanis CL, Boerwinkle E, Chakraborty R, Ellsworth DL, Concannon P, Stirling B, Morrison VA, Wapelhorst B, Spielman RS, Gogolin-Ewens KJ, Shephard JM, Williams SR, Risch N, Hinds D, Iwasaki N, Ogata M, Omori Y, Petzold C, Rietzsch H, Schröder H-E, Schulze J, Cox NJ, Menzel S, Boriraj VV, Chen X, Um LR, Lindner T, Mereu LE, Wang Y-Q, Xiang K, Yamagata K, Yang Y, Bell GI: A genome-wide search for human non-insulin-dependent (type 2) diabetes genes reveals a major susceptibility locus on chromosome 2. Nature Genet 13:161-166, 1996
4. + channel: no evidence for linkage in maturity-onset diabetes of the young or NIDDM. Diabetes 45:639-641, 1996
5. Lehn DA, Brown LJ, Simonson GD, Moran SM, MacDonald MJ: The Sequence of a human mitochondrial glycerol-3-phosphate dehydrogenase-encoding cDNA. Gene 150:417-418, 1994
6. MacDonald MJ, Brown LJ: Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudied. Arch Biochem Biophys 326:79-84, 1996
7. Takeuchi Y, Matsutani A, Oka Y: Detection of variants in the mitochondrial glycerophosphate dehydrogenase gene in Japanese patients. Diabetologia 40:339-343, 1997
8. Brown LJ, Stoffel M, Fernald AA, Moran SM, Lehn DA, LeBeau MM, Mac-Donald MJ: Structural organization and mapping of the human mitochondrial glycerol phosphate dehydrogenase-encoding gene and pseudogene. Gene 172:309-312, 1996
9. Novials A, Vidal J, France C, Ribera F, Sener A, Malaisse WJ, Gomis R: Mutation in the calcium-binding domain of the mitochondrial glycerophosphate dehydrogenase gene in a family of diabetic subjects. Biochem Biophys Res Comm 231:570-572, 1997