-
1
-
-
0021707433
-
Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis
-
Benveniste H, Drejer J, Schousboe A, Diemer NH. Elevation of the extracellular concentrations of glutamate and aspartate in rat hippocampus during transient cerebral ischemia monitored by intracerebral microdialysis. J Neurochem 1984;43:1369-1374
-
(1984)
J Neurochem
, vol.43
, pp. 1369-1374
-
-
Benveniste, H.1
Drejer, J.2
Schousboe, A.3
Diemer, N.H.4
-
2
-
-
0021743001
-
Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain
-
Simon RP, Swan JH, Griffiths T, Meldrum BS. Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain. Science 1984;226:850-852
-
(1984)
Science
, vol.226
, pp. 850-852
-
-
Simon, R.P.1
Swan, J.H.2
Griffiths, T.3
Meldrum, B.S.4
-
3
-
-
0027207494
-
Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions
-
Wahlestedt C, Golanov E, Yamamoto S, et al. Antisense oligodeoxynucleotides to NMDA-R1 receptor channel protect cortical neurons from excitotoxicity and reduce focal ischaemic infarctions. Nature 1993;363:260-263
-
(1993)
Nature
, vol.363
, pp. 260-263
-
-
Wahlestedt, C.1
Golanov, E.2
Yamamoto, S.3
-
4
-
-
0025117827
-
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: A neuroprotectant for cerebral ischemia
-
Sheardown MJ, Nielsen EØ, Hansen AJ, et al. 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia. Science 1990;247:571-574
-
(1990)
Science
, vol.247
, pp. 571-574
-
-
Sheardown, M.J.1
Nielsen, E.Ø.2
Hansen, A.J.3
-
6
-
-
0025232442
-
The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity
-
Weiss JH, Hartley DM, Koh J, Choi DW. The calcium channel blocker nifedipine attenuates slow excitatory amino acid neurotoxicity. Science 1990;247:1474-1477
-
(1990)
Science
, vol.247
, pp. 1474-1477
-
-
Weiss, J.H.1
Hartley, D.M.2
Koh, J.3
Choi, D.W.4
-
7
-
-
0029614765
-
Neural apoptosis
-
Bredesen DE. Neural apoptosis. Ann Neurol 1995;38:839-851
-
(1995)
Ann Neurol
, vol.38
, pp. 839-851
-
-
Bredesen, D.E.1
-
8
-
-
0027501851
-
Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
-
Linnik MD, Zobrist RH, Hatfield MD. Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 1993;24:2002-2009
-
(1993)
Stroke
, vol.24
, pp. 2002-2009
-
-
Linnik, M.D.1
Zobrist, R.H.2
Hatfield, M.D.3
-
9
-
-
0027369909
-
Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain
-
Héron A, Pollard H, Dessi F, et al. Regional variability in DNA fragmentation after global ischemia evidenced by combined histological and gel electrophoresis observations in the rat brain. J Neurochem 1993;61:1973-1976
-
(1993)
J Neurochem
, vol.61
, pp. 1973-1976
-
-
Héron, A.1
Pollard, H.2
Dessi, F.3
-
10
-
-
0027714833
-
Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain
-
MacManus JP, Buchan AM, Hill IE, et al. Global ischemia can cause DNA fragmentation indicative of apoptosis in rat brain. Neurosci Lett 1993;164:89-92
-
(1993)
Neurosci Lett
, vol.164
, pp. 89-92
-
-
MacManus, J.P.1
Buchan, A.M.2
Hill, I.E.3
-
11
-
-
0028898676
-
Detection of DNA damage induced by apoptosis in the rat brain following incomplete ischemia
-
Islam N, Aftabuddin M, Moriwaki A, Hori Y. Detection of DNA damage induced by apoptosis in the rat brain following incomplete ischemia. Neurosci Lett 1995;188:159-162
-
(1995)
Neurosci Lett
, vol.188
, pp. 159-162
-
-
Islam, N.1
Aftabuddin, M.2
Moriwaki, A.3
Hori, Y.4
-
12
-
-
0029127992
-
Selective neuronal vulnerability in the hippocampus - A role for gene expression?
-
Schreiber SS, Baudry M. Selective neuronal vulnerability in the hippocampus - a role for gene expression? Trends Neurosci. 1995;18:446-451
-
(1995)
Trends Neurosci.
, vol.18
, pp. 446-451
-
-
Schreiber, S.S.1
Baudry, M.2
-
13
-
-
0029884441
-
Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia
-
Chen J, Zhu RL, Nakayama M, et al. Expression of the apoptosis-effector gene, Bax, is up-regulated in vulnerable hippocampal CA1 neurons following global ischemia. J Neurochem 1996;67:64-71
-
(1996)
J Neurochem
, vol.67
, pp. 64-71
-
-
Chen, J.1
Zhu, R.L.2
Nakayama, M.3
-
14
-
-
0028973310
-
Upregulation of Bax protein levels in neurons following cerebral ischemia
-
Krajewski S, Mai JK, Krajewska M, et al. Upregulation of Bax protein levels in neurons following cerebral ischemia. J Neurosci 1995;15:6364-6376
-
(1995)
J Neurosci
, vol.15
, pp. 6364-6376
-
-
Krajewski, S.1
Mai, J.K.2
Krajewska, M.3
-
15
-
-
0028355216
-
DNA damage consistent with apoptosis in transient focal ischaemic neocortex
-
MacManus JP, Hill IE, Huang ZG, et al. DNA damage consistent with apoptosis in transient focal ischaemic neocortex. Neuroreport 1994;5:493-496
-
(1994)
Neuroreport
, vol.5
, pp. 493-496
-
-
MacManus, J.P.1
Hill, I.E.2
Huang, Z.G.3
-
16
-
-
0030053303
-
Apoptosis and necrosis after reversible focal ischemia: An in situ DNA fragmentation analysis
-
Charriaut-Marlangue C, Margaill I, Represa A, et al. Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis. J Cereb Blood Flow Metab 1996;16: 186-194
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 186-194
-
-
Charriaut-Marlangue, C.1
Margaill, I.2
Represa, A.3
-
17
-
-
0029691054
-
Apoptosis in focal cerebral ischemia
-
Wien
-
Chopp M, Li Y. Apoptosis in focal cerebral ischemia. Acta Neurochir Suppl (Wien) 1996;66:21-26
-
(1996)
Acta Neurochir Suppl
, vol.66
, pp. 21-26
-
-
Chopp, M.1
Li, Y.2
-
18
-
-
0000064578
-
Altered expression of Bcl-2 Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats
-
Gillardon F, Lenz C, Waschke KF, et al. Altered expression of Bcl-2 Bcl-X, Bax, and c-Fos colocalizes with DNA fragmentation and ischemic cell damage following middle cerebral artery occlusion in rats. Mol Brain Res 1996;40:254-260
-
(1996)
Mol Brain Res
, vol.40
, pp. 254-260
-
-
Gillardon, F.1
Lenz, C.2
Waschke, K.F.3
-
19
-
-
0029796809
-
Apoptotic death in cortical neurons of mice subjected to focal ischemia
-
III
-
Guegan C, Boutin H, Boudry C, et al. Apoptotic death in cortical neurons of mice subjected to focal ischemia. C R Acad Sci [III] 1996;319:879-885
-
(1996)
C R Acad Sci
, vol.319
, pp. 879-885
-
-
Guegan, C.1
Boutin, H.2
Boudry, C.3
-
20
-
-
0027399025
-
The protooncogene bcl-2 inhibits apoptosis in PC12 cells
-
Mah SP, Zhong LT, Liu Y, et al. The protooncogene bcl-2 inhibits apoptosis in PC12 cells. J Neurochem 1993;60:1183-1186
-
(1993)
J Neurochem
, vol.60
, pp. 1183-1186
-
-
Mah, S.P.1
Zhong, L.T.2
Liu, Y.3
-
21
-
-
0027717968
-
Bcl-2 inhibition of neural death: Decreased generation of reactive oxygen species
-
Kane DJ, Sarafian TA, Anton R, et al. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species. Science 1993;262:1274-1277
-
(1993)
Science
, vol.262
, pp. 1274-1277
-
-
Kane, D.J.1
Sarafian, T.A.2
Anton, R.3
-
23
-
-
0030025668
-
Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo
-
Lawrence MS, Ho DY, Sun GH, et al. Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo. J Neurosci 1996;16: 486-496
-
(1996)
J Neurosci
, vol.16
, pp. 486-496
-
-
Lawrence, M.S.1
Ho, D.Y.2
Sun, G.H.3
-
24
-
-
0027944004
-
Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia
-
Martinou J-C, Dubois-Dauphin M, Staple JK, et al. Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia. Neuron 1994;13:1017-1030
-
(1994)
Neuron
, vol.13
, pp. 1017-1030
-
-
Martinou, J.-C.1
Dubois-Dauphin, M.2
Staple, J.K.3
-
25
-
-
0028798574
-
Bcl-2 is expressed in neurons that survive focal ischemia in the rat
-
Chen J, Graham SH, Chan PH, et al. Bcl-2 is expressed in neurons that survive focal ischemia in the rat. Neuroreport 1995;6:394-398
-
(1995)
Neuroreport
, vol.6
, pp. 394-398
-
-
Chen, J.1
Graham, S.H.2
Chan, P.H.3
-
26
-
-
0028981908
-
Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia
-
Linnik MD, Zahos P, Geschwind MD, Federoff HJ. Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia. Stroke 1995;26: 1670-1675
-
(1995)
Stroke
, vol.26
, pp. 1670-1675
-
-
Linnik, M.D.1
Zahos, P.2
Geschwind, M.D.3
Federoff, H.J.4
-
27
-
-
0027240081
-
Tau protein kinase I is essential for amyloid β-protein-induced neurotoxicity
-
Takashima A, Noguchi K, Sato K, et al. Tau protein kinase I is essential for amyloid β-protein-induced neurotoxicity. Proc Nad Acad Sci USA 1993;90:7789-7793
-
(1993)
Proc Nad Acad Sci USA
, vol.90
, pp. 7789-7793
-
-
Takashima, A.1
Noguchi, K.2
Sato, K.3
-
28
-
-
0027160059
-
A Tau antisense oligonucleotide decreases neurone sensitivity to excitotoxic injury
-
Pizzi M, Valerio A, Ribola M, et al. A Tau antisense oligonucleotide decreases neurone sensitivity to excitotoxic injury. Neuroreport 1993;4:823-826
-
(1993)
Neuroreport
, vol.4
, pp. 823-826
-
-
Pizzi, M.1
Valerio, A.2
Ribola, M.3
-
30
-
-
0028923784
-
A BDNF autocrine loop in adult sensory neurons prevents cell death
-
Acheson A, Conover JC, Fandl JP, et al. A BDNF autocrine loop in adult sensory neurons prevents cell death. Nature 1995; 374:450-453
-
(1995)
Nature
, vol.374
, pp. 450-453
-
-
Acheson, A.1
Conover, J.C.2
Fandl, J.P.3
-
31
-
-
0028270620
-
The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development
-
Barrett GL, Bartlett PF. The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development. Proc Natl Acad Sci USA 1994;91:6501-6505
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6501-6505
-
-
Barrett, G.L.1
Bartlett, P.F.2
-
32
-
-
0028221169
-
Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells
-
Troy CM, Shelanski ML. Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells Proc Natl Acad Sci USA 1994;91:6384-6387
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6384-6387
-
-
Troy, C.M.1
Shelanski, M.L.2
-
33
-
-
0028205372
-
Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons
-
Rothstein JD, Bristol LA, Hosler B, et al. Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons. Proc Natl Acad Sci USA 1994;91:4155-4159
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 4155-4159
-
-
Rothstein, J.D.1
Bristol, L.A.2
Hosler, B.3
-
34
-
-
0022476899
-
Effects of arachidonic acid on glutamate and γ-aminobutyric acid uptake in primary cultures of rat cerebral cortical astrocytes and neurons
-
Yu ACH, Chan PH, Fishman RA. Effects of arachidonic acid on glutamate and γ-aminobutyric acid uptake in primary cultures of rat cerebral cortical astrocytes and neurons. J Neurochem 1986;47:1181-1189
-
(1986)
J Neurochem
, vol.47
, pp. 1181-1189
-
-
Yu, A.C.H.1
Chan, P.H.2
Fishman, R.A.3
-
35
-
-
0027249667
-
A new fluorometric assay for cytotoxicity measurements in vitro
-
Pagé B, Pagé M, Noël C. A new fluorometric assay for cytotoxicity measurements in vitro. Int J Oncol 1993;3:473-476
-
(1993)
Int J Oncol
, vol.3
, pp. 473-476
-
-
Pagé, B.1
Pagé, M.2
Noël, C.3
-
36
-
-
0030605279
-
Assessment of neuronal viability with Alamar blue in cortical and granule cell cultures
-
White MJ, DiCaprio MJ, Greenberg DA. Assessment of neuronal viability with Alamar blue in cortical and granule cell cultures. J Neurosci Methods 1996;70:195-200
-
(1996)
J Neurosci Methods
, vol.70
, pp. 195-200
-
-
White, M.J.1
DiCaprio, M.J.2
Greenberg, D.A.3
-
37
-
-
0026498607
-
Ethanol and excitotoxicity in cultured cortical neurons: Differential sensitivity of N-methyl-D-aspartate and sodium nitroprusside toxicity
-
Lustig HS, von Brauchitsch KL, Chan J, Greenberg DA. Ethanol and excitotoxicity in cultured cortical neurons: differential sensitivity of N-methyl-D-aspartate and sodium nitroprusside toxicity. J Neurochem 1992;59:2193-2200
-
(1992)
J Neurochem
, vol.59
, pp. 2193-2200
-
-
Lustig, H.S.1
Von Brauchitsch, K.L.2
Chan, J.3
Greenberg, D.A.4
-
38
-
-
0343467342
-
Inhibition of bcl-2 protein expression by antisense S-oligodeoxynucleotide treatment exacerbates neuronal death after cerebral ischemia in rats
-
Chen J, Zhu R, Basta K, et al. Inhibition of bcl-2 protein expression by antisense S-oligodeoxynucleotide treatment exacerbates neuronal death after cerebral ischemia in rats. Neurology 1996;46:A270-A271
-
(1996)
Neurology
, vol.46
-
-
Chen, J.1
Zhu, R.2
Basta, K.3
-
39
-
-
0343814756
-
Apoptosis repressor gene bcl-2: Potential role in ischemic tolerance
-
Krieglstein J, ed. Stuttgart: Medpharm
-
Simon RP, Chen J. Apoptosis repressor gene bcl-2: potential role in ischemic tolerance. In: Krieglstein J, ed. Pharmacology of cerebral ischemia 1996. Stuttgart: Medpharm, 1996:25-31
-
(1996)
Pharmacology of Cerebral Ischemia 1996
, pp. 25-31
-
-
Simon, R.P.1
Chen, J.2
-
41
-
-
0029097470
-
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax
-
Sedlak TW, Oltvai ZN, Yang E, et al. Multiple Bcl-2 family members demonstrate selective dimerizations with Bax. Proc Natl Acad Sci USA 1995;92:7834-7838
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 7834-7838
-
-
Sedlak, T.W.1
Oltvai, Z.N.2
Yang, E.3
-
42
-
-
0030004872
-
Facilitating oligonucleotide delivery: Helping antisense deliver on its promise
-
Gewirtz AM, Stein CA, Glazer PM. Facilitating oligonucleotide delivery: helping antisense deliver on its promise. Proc Natl Acad Sci USA 1996;93:3161-3163
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3161-3163
-
-
Gewirtz, A.M.1
Stein, C.A.2
Glazer, P.M.3
-
43
-
-
0028060247
-
Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bd-2 gene expression
-
Kitada S, Takayama S, De Riel K, et al. Reversal of chemoresistance of lymphoma cells by antisense-mediated reduction of bd-2 gene expression. Antisense Res Dev 1994;4:71-79
-
(1994)
Antisense Res Dev
, vol.4
, pp. 71-79
-
-
Kitada, S.1
Takayama, S.2
De Riel, K.3
-
44
-
-
0028019410
-
Gene inhibition using antisense oligodeoxynucleotides
-
Wagner RW. Gene inhibition using antisense oligodeoxynucleotides. Nature 1994;372:333-335
-
(1994)
Nature
, vol.372
, pp. 333-335
-
-
Wagner, R.W.1
-
45
-
-
0029812567
-
A nonantisense sequence-selective effect of a phosphorothioate oligodeoxynucleotide directed against the epidermal growth factor receptor in A431 cells
-
Coulson JM, Poyner DR, Chantry A, et al. A nonantisense sequence-selective effect of a phosphorothioate oligodeoxynucleotide directed against the epidermal growth factor receptor in A431 cells. Mol Pharmacol 1996;50:314-325
-
(1996)
Mol Pharmacol
, vol.50
, pp. 314-325
-
-
Coulson, J.M.1
Poyner, D.R.2
Chantry, A.3
-
46
-
-
0029814808
-
Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra
-
Furlan M, Marchai G, Viadler F, et al. Spontaneous neurological recovery after stroke and the fate of the ischemic penumbra. Ann Neurol 1996;40:216-226
-
(1996)
Ann Neurol
, vol.40
, pp. 216-226
-
-
Furlan, M.1
Marchai, G.2
Viadler, F.3
|