Conformation of factor VIIa stabilized by a labile disulfide bond (Cys- 310-Cys-329) in the protease domain is essential for interaction with tissue factor

Journal of Biological Chemistry

Volumn 272, Issue 41, 1997, Pages 25724-25730

  Higashi, Shouichi ^a,c   Matsumoto, Naomi ^a   Iwanaga, Sadaaki ^a,b  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 7A; PROTEINASE; SERINE PROTEINASE; THROMBOPLASTIN; TRYPSIN; TRYPSINOGEN;

AMINO ACID ANALYSIS; AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ARTICLE; CRYSTAL STRUCTURE; DISULFIDE BOND; ENZYME ACTIVATION; METHYLATION; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; REDUCTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; BINDING SITES; CATTLE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DISULFIDES; FACTOR VIIA; HUMANS; MERCAPTOETHANOL; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; PEPTIDE MAPPING; RECOMBINANT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP; THROMBOPLASTIN;

EID: 0030798989     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.41.25724     Document Type: Article

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