Interaction of thiostrepton with an RNA fragment derived from the plastid-encoded ribosomal RNA of the malaria parasite

RNA

Volumn 3, Issue 8, 1997, Pages 815-820

  Rogers, M John ^a   Bukhman, Yury V ^b   McCutchan, Thomas F ^a   Draper, David E ^b  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Antibiotic; Plasmodium falciparum; Ribosome; RNA hyperchromicity; Transcription

Indexed keywords

RIBOSOME RNA; THIOSTREPTON;

ANTIBIOTIC SENSITIVITY; ARTICLE; BINDING SITE; CELL ORGANELLE; DRUG BINDING; DRUG PROTEIN BINDING; GROWTH INHIBITION; PHENOTYPE; PLASMODIUM; PLASMODIUM FALCIPARUM; PLASTID; POINT MUTATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; PROTEIN TERTIARY STRUCTURE; RNA ANALYSIS; RNA TRANSCRIPTION; TEMPERATURE DEPENDENCE;

ANIMALS; BASE SEQUENCE; BINDING SITES; MAGNESIUM; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEIC ACID CONFORMATION; PLASMODIUM FALCIPARUM; PLASTIDS; QUATERNARY AMMONIUM COMPOUNDS; RNA, PROTOZOAN; RNA, RIBOSOMAL, 23S; SODIUM; SUBSTRATE SPECIFICITY; THIOSTREPTON;

BACTERIA (MICROORGANISMS); ESCHERICHIA; EUKARYOTA; PLASMODIUM FALCIPARUM;

EID: 0030791711     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Beckers CJ, Roos DS, Donald RG, Luft BJ, Schwab JC, Cao Y, Joiner KA, 1995. Inhibition of cytoplasmic and organellar protein synthesis in Toxoplasma gondii. Implications for the target of macrolide antibiotics. J Clin Invest 95:367-376.
2. Brink MF, Brink G, Ph. Verbeet M, de Boer HA. 1994. Spectinomycin interacts specifically with the residues G1064 and C 1192 in 16S rRNA, thereby potentially freezing this molecule into an inactive conformation. Nucleic Acids Res 22:325-331.
3. Chiu ML, Flocher M, Griffin P, Holt T, Klatt T, Thompson CJ. 1996. Characterization of the covalent binding of thiostrepton to a thiostrepton-induced protein from Streptomyces lividans. Biochemistry 35:2332-2341.
4. Cundliffe E. 1990. Recognition sites for antibiotics within rRNA. In: Hill WE, et al. eds. The ribosome, structure, function and evolution. Washington, DC: ASM Press. pp 479-490.
5. Cundliffe E, Thompson J. 1981. Concerning the mode of action of micrococcin upon bacterial protein synthesis. Eur J Biochem 118: 47-52.
6. Draper DE, Xing Y, Laing LG. 1995. Thermodynamics of RNA folding: Stabilization of a conserved ribosomal RNA tertiary structure by an antibiotic and ammonium ions. J Mol Biol 249:231-238.
7. Egea N, Lang-Unnasch N. 1995. Phylogeny of the large extrachromosomal DNA of organisms in the phylum Apicomplexa. J Eukaryot Microbiol 42:679-684.
8. Feagin JE, Gardner MJ, Williamson DH, Wilson RJ. 1991. The putative mitochondrial genome of Plasmodium falciparum. J Protozool 38:243-245.
9. Feagin JE, Mericle BL, Werner E, Morris M. 1997. Identification of additional rRNA fragments encoded by the Plasmodium falciparum 6 kb element. Nucleic Acids Res 25:438-446.
10. Feagin JE, Werner E, Gardner MJ, Williamson DH, Wilson RJ. 1992. Homologies between the contiguous and fragmented rRNAs of the two Plasmodium falciparum extrachromosomal DNAs are limited to core sequences. Nucleic Acids Res 20:879-887.
11. Fountain MA, Serra MJ, Krugh TR, Turner DH. 1996. Structural features of a six nucleotide RNA hairpin loop found in ribosomal RNA. Biochemistry 35:6539-6548.
12. Fourmy D, Recht Ml, Blanchard S, Puglisi JD. 1996. Structure of the A site of Eschrichia coli 16S ribosomal RNA completed with an aminoglycoside antibiotic. Science 274:1367-1371.
13. Gardner MJ, Feagin JE, Moore DJ, Rangachari K, Williamson DH, Wilson RJM. 1993. Sequence and organization of large subunit rRNA genes from the extrachromosomal 35 kb circular DNA of the malaria parasite Plasmodium falciparum. Nucleic Acids Res 21:1067-1071.
14. Gluick TC, Draper DE. 1994. Thermodynamics of folding a pseudo-knotted mRNA fragment. J Mol Biol 241:246-262.
15. Gozar MM, Bagnara AS. 1995. An orgnelle-like small subunit ribosomal RNA gene from Babesia bovis: Nucleotide sequence, secondary structure of the transcript and preliminary phylogenetic analysis. Int J Parasitol 25:929-938.
16. Gutell RR, Schnare MN, Gray MW. 1992. A compilation of large subunit (23S- and 23S-like) ribosomal RNA structures. Nucleic Acids Res 20:2095-2109.
17. Huang S, Wang YX, Draper DE. 1996. Structure of a hexanucleotide RNA hairpin loop conserved in ribosomal RNAS. J Mol Biol 258:308-321.
18. Laing LG, Draper DE. 1994. Thermodynamics of RNA folding in a conserved ribosomal RNA domain. J Mol Biol 23 7:560-576.
19. Laing LG, Gluick TC, Draper DE. 1994. Stabilization of RNA structure by Mg ions. Specific and non-specific effects. J Mol Biol 23 7:577-587.
20. Mankin AS, Leviev IG, Garrett RA. 1994. Cross-hypersensitivity effects of mutations in 23 S rRNA yield insight into aminoacyl-tRNA binding. J Mol Bid 244:151-157.
21. McConkey GA, Rogers MJ, McCutchan TF. 1997. Inhibition of Plasmodium falciparum protein synthesis: Targeting the plastid-like organelle with thiostrepton. J Biol Chem 272:2046-2049.
22. McCutchan TF, Li J, McConkey GA, Rogers MJ, Waters AP. 1995. The cytoplasmic ribosomal RNAs of Plasmodium spp. Parasitol Today 11:134-138.
23. Moazed D, Noller HF. 1987a. Interaction of antibiotics with functional sites in 16S RNA. Nature 327:389-394.
24. Moazed D, Noller HF. 1987b. Chloramphenicol, erythromycin, carbomycin and vernamycin B protect overlapping sites in the peptidyl transferase region of 23S ribosomal RNA. Biochimie 69:879-884.
25. Murakami T, Holt TG, Thompson CJ. 1989. Thiostrepton-induced gene expression in Streptomyces lividans. J Bacteriol 171:1459-1466.
26. Palmer JD, Delwiche CF. 1996. Second-hand chloroplasts and the case of the disappearing nucleus. Proc Natl Acad Sci USA 93:7432-7435.
27. Rogers KC, Söll D. 1993. Discrimination among tRNAs intermediate in glutamate and glutamine identity. Biochemistry 32:14210-14219.
28. Rogers MJ, Gutell RR, Damberger SH, Li J, McConkey GA, Waters AP, McCutchan TF. 1996. Structural features of the large subunit rRNA expressed in Plasmodium falciparum sporozoites that distinguish it from the asexually expressed subunit rRNA. RNA 2:134-145.
29. Rosendahl G, Douthwaite S. 1994. The antibiotics micrococcin and thiostrepton interact directly with 23S rRNA nucleotides 1067A and 1095A. Nucleic Acids Res 22 357-363.
30. Ryan PC, Draper DE. 1991. Detection of a key tertiary interaction in the highly conserved GTPase center of large subunit ribosomal RNA. Proc Natl Acad Sci USA 88:6308-6312.
31. Sampson JR, UhlenbecK OC. 1988. Biochemical and physical characterization of an unmodified yeast phenylalanine transfer RNA transcribed in vitro. Proc Natl Acad Sci USA 85:1033-1037.
32. Thompson J, Cundliffe E. 1991. The binding of thiostrepton to 23S ribosomal RNA. Biochimie 73:1131-1135.
33. Thompson J, Cundliffe E, Dahlberg AE. 1988. Site-directed mutagenesis of Escherichia coli 23S ribosomal RNA at position 1067 within the GTP hydrolysis centre. J Mol Biol 203:457-465.
34. Wang YX, Lu M, Draper DE. 1993. Specific ammonium ion requirement for functional ribosomal RNA tertiary structure. Biochemistry 32:12279-12282.
35. Waters AP, White W, McCutchan TF. 1995. The structure of the large subunit rRNA expressed in blood stages of Plasmodium falciparum. Mol Biochem Parasitol 72 227-237.
36. Weeks KM, Cech TR. 1996. Assembly of a ribonucleoprotein catalyst by tertiary structure capture. Science 271:345-348.
37. Wilson RJM, Denny PW, Preiser PR, Rangachari K, Roberts K, Roy A, Whyte A, Strath M, Moore DJ, Moore PW, Williamson DH. 1996. Complete gene map of the plastid-like DNA of the malaria parasite Plasmodium falciparum. J Mol Biol 261 155-172.
38. Wilson RJM, Williamson DH, Preiser P. 1994. Malaria and other Apicomplexans: The "plant" connection. Infectious Agents and Disease 3:29-37.
39. Xing Y, Draper DE. 1995. Stabilization of a ribosomal RNA tertiary structure by ribosomal protein L11. J Mol Biol 249:319-331.