Polyamine biosynthesis in Cryptosporidium parvum and its implications for chemotherapy

Molecular and Biochemical Parasitology

Volumn 88, Issue 1-2, 1997, Pages 35-42

  Keithly, Janet S ^a   Zhu, Guan ^a   Upton, Steve J ^b   Woods, Keith M ^b   Martinez, Martha P ^c   Yarlett, Nigel ^c  

^a WADSWORTH CENTER   (United States)

^b KANSAS STATE UNIVERSITY   (United States)

^c PACE UNIVERSITY   (United States)

Author keywords

Arginine decarboxylase; Chemotherapy; Cryptosporidium; Difluoromethylarginine; Polyamines; Spermine:Spermidine N1 acetyltransferase

Indexed keywords

ACYLTRANSFERASE; CARBOXYLASE; POLYAMINE; PUTRESCINE; SPERMIDINE; SPERMINE;

ARTICLE; CHEMOTHERAPY; CRYPTOSPORIDIUM PARVUM; ENZYME ACTIVITY; ENZYME SPECIFICITY; GROWTH INHIBITION; INTRACELLULAR RECORDING; PLANT; POLYAMINE METABOLISM; PRIORITY JOURNAL; TUMOR CELL CULTURE;

ACETYLTRANSFERASES; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANIMALS; CARBOXY-LYASES; COCCIDIOSTATS; CRYPTOSPORIDIOSIS; CRYPTOSPORIDIUM PARVUM; EFLORNITHINE; ENZYME INHIBITORS; HUMANS; POLYAMINES; SPERMINE;

CRYPTOSPORIDIUM; CRYPTOSPORIDIUM PARVUM; EUKARYOTA;

EID: 0030788337     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00063-7     Document Type: Article

References (29)

1. Flanigan TP, Soave R. Cryptosporidiosis. Prog Clin Parasitol 1993;3:1-20.
2. Sterling CR, Arrowood MJ. Cryptosporidia. In: Kreier JP, editor. Parasitic Protozoa. New York: Academic Press, 1993:159-225.
3. Tilley M, Upton SJ. Biochemistry of Cryptosporidium. In: Payer R, editor. Cryptosporidium and Cryptosporidiosis. NY/London: CRC Press, 1997:163-80.
4. Denton H, Brown SMA, Roberts CW, Alexander J, McDonald V, Thong K-W, Coombs GH. Comparison of the phosphofructokinase and pyruvate kinase activities of Cryptosporidium parvum, Eimeria tenella and Toxoplasma gondii. Mol Biochem Parasitol 1996;76:23-9.
5. Bacchi CJ, Yarlett N. Polyamine metabolism. In: Marr JJ, Müller M, editors. Biochemistry and Molecular Biology of Parasites. New York: Academic Press, 1995:119-31.
6. Nixon SE, Mawer GE. The digestion and absorption of protein in man. 2. The form in which protein is absorbed. Br Med J 1970;246:215-9.
7. Rolston KV, Fainstein V, Bodey GP. Intestinal cryptosporidiosis treated with eflornithine: A prospective study among patients with AIDS. J Acquired Immune Defic Syndr 1989;2:426-30.
8. Lemeteil D, Roussel F, Favennec L, Ballet JJ, Brasseur P. Assessment of candidate anticryptosporidian agents in an immunosuppressed rat model. J Infect Dis 1993;167:766-8.
9. Slocum RD. Polyamine biosynthesis in plants. In: Slocum RD, Flores HE, editors. Biochemistry and Physiology of Polyamines in Plants. Boca Raton, FL: CRC Press, 1991:24-37.
10. Tabor CW, Tabor H. Polyamines in microorganisms. Microbiol Rev 1985;49:81-99.
11. Upton SJ, Tilley M, Nesterenko MV, Brillhart DB. A simple and reliable method for producing in vitro infections of Cryptosporidium parvum (Apicomplexa). FEMS Microbiol Lett 1994;118:45-50.
12. Nesterenko MV, Upton SJ. A rapid microcentrifuge procedure for purification of Cryptosporidium parvum sporozoites. J Microbiol Methods 1996;25:87-9.
13. Smith TA. Arginine decarboxylase (oat seedlings). Methods Enzymol 1983;94:176-80.
14. 1-acetyltransferase activity by spermine analogues and their relationship to polyamine depletion and growth inhibition in L1210 cells. Cancer Res 1989;49:6226-31.
15. Janne J, Williams-Ashman HG. On the purification of L-ornithine decarboxylase from rat prostate and effects of thiol compounds on the enzyme. J Biol Chem 1971;246:1725-32.
16. Yarlett N, Bacchi CJ. Effect of DL-α-difluoromethylornithine on polyamine synthesis and interconversion in Trichomonas vaginalis. Mol Biochem Parasitol 1988;31:1-10.
17. Woods KM, Nesterenko MV, Upton SJ. Development of a microtitre ELISA to quantitate development of Cryptosporidium parvum in vitro. FEMS Microbiol Lett 1995;128:89-93.
18. Upton SJ, Tilley M, Brillhart DB. Effect of select media supplements on in vitro development of Cryptosporidium parvum in HCT-8 cells. J Clin Microbiol 1995;33:371-5.
19. Hunter KJ, Strobos CA, Fairlamb AH. Inhibition of polyamine biosynthesis in Crithidia fasciculata by DL-α-difluoromethyl-ornithine and DL-α-difluoromethyl-arginine. Mol Biochem Parasitol 1991;46:35-43.
20. 1-acetyltransferase (SSAT) - an emerging target for the design of antitumour agents. Curr Opin Invest Drugs 1993;2:1291-9.
21. Isel TR, Murphy DL, Cohen RM, Alterman I, Kilts C, Linnoila M. Obsessive-compulsive disorder. A double-blind trial of clomipramine and clorgyline. Arch Gen Psychiatry 1983;40:605-12.
22. Kohler S, Delwiche CF, Denny PW, Tilney P, Webster P, Wilson RJM, Palmer JD, Roos DS. A plastid of probable green algal origin in apicomplexan parasites. Science 1997;275:1485-9.
23. Blunt DS, Khramtsov NV, Upton JS, Montelone BA. Molecular karyotype analysis of Cryptosporidium parvum: evidence for eight chromosomes and a low molecular-size molecule. Clin Diag Lab Immunol 1997;4:11-3.
24. Keeling PJ, Doolittle WF. Alpha-tubulin from early diverging eukaryotic lineages and the evolution of the tubulin family. Mol Biochem Evol 1997;13:331-8.
25. Bacchi CJ, McCann PP. Parasitic protozoa and polyamines. In: McCann PP, Pegg AE, Sjoerdsma A, editors. Inhibition of Polyamine Metabolism. New York: Academic Press, 1987:317-44.
26. Keithly JS, Fairlamb AH. Inhibiton of Leishmania species by α-difluoro-methylornithine. In: Hart DT, editor. Leishmaniasis: Current Status and New Strategies for Control. New York: Plenum Publishers, 1989:746-56.
27. Majumdar S, Wirth J, Bitonti AJ, McCann PP, Kierszenbaum F. Biochemical evidence for the presence of arginine decarboxylase activity in Trypanosoma cruzi. J Parasitol 1992;78:371-4.
28. Li G, Regunathan S, Barrow CJ, Eshraghi J, Cooper R, Reis DJ. Agmatine: an endogenous clonidine-displacing substance in the brain. Science 1994;263:966-8.
29. Buch JK, Boyle SM. Biosynthetic arginine decarboxylase in Escherichia coli is synthesized as a precursor and located in the cell envelope. J Bacteriol 1985;163:522-7.