Mutation watch: Mouse brachyury (T), the T-box gene family, and human disease

Mammalian Genome

Volumn 8, Issue 11, 1997, Pages 799-800

  Meisler, Miriam H ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRACHYURY PROTEIN; DNA BINDING PROTEIN; FETOPROTEIN; T BOX TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR;

ANIMAL; CONGENITAL HEART MALFORMATION; CONGENITAL MALFORMATION; GENETICS; GENOTYPE; HUMAN; LIMB MALFORMATION; MESODERM; MORPHOGENESIS; MOUSE; MULTIPLE MALFORMATION SYNDROME; PHENOTYPE; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW; SYNDROME; TAIL;

ABNORMALITIES, MULTIPLE; ANIMALS; DNA-BINDING PROTEINS; EMBRYONIC AND FETAL DEVELOPMENT; FETAL PROTEINS; GENOTYPE; HEART DEFECTS, CONGENITAL; HUMANS; LIMB DEFORMITIES, CONGENITAL; MESODERM; MICE; MORPHOGENESIS; PHENOTYPE; SYNDROME; T-BOX DOMAIN PROTEINS; TAIL; TRANSCRIPTION FACTORS;

EID: 0030779366     PISSN: 09388990     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003359900581     Document Type: Review

References (10)

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7. Herrmann BG, Labeit S, Poustka A, King TR, Lehrach H (1990) Cloning of the T gene required in mesoderm formation in the mouse. Nature 343, 617-622
8. Kispert A, Koschorz B, Herrmann BG (1995) The T protein encoded by brachyury is a tissue-specific transcription factor. EMBO J 14, 4763-4772
9. Li QY, Newbury-Ecob RA, Terrett JA, Wilson DI, Curtis ARJ, Yi CH, Gebuhr T, Bullen PJ, Robson SC, Strachan T, Bonnet D, Lyonnet S, Young ID, Raeburn JA, Buckler AJ, Law DJ, Brook JD (1997) Holt-Oram Syndrome is caused by mutations in TBX5, a member of Brachyury (T) family. Nature Genet 15, 21-29
10. Pflugfelder GO, Roth H, Poeck B (1992) A homology domain shared between Drosophila optomotor-blind and mouse brachyury is involved in DNA binding. Biochem Biophys Res Commun 186, 918-925