Heavy chain CDR3 optimization of a germline encoded recombinant antibody fragment predisposed to bind the U1A protein

Protein Engineering

Volumn 10, Issue 7, 1997, Pages 835-841

  De Wildt, Ruud M T ^a   Ruytenbeek, Rob ^a   Van Venrooij, Walther J ^a   Hoet, René M A ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Autoantibody; CDR3; Phage display library; U1A protein

Indexed keywords

AMINO ACID; AUTOANTIGEN; IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN HEAVY CHAIN; MUTANT PROTEIN; RECOMBINANT PROTEIN; RIBONUCLEOPROTEIN;

ANTIBODY AFFINITY; ANTIGEN BINDING; ARTICLE; BINDING AFFINITY; CONSENSUS SEQUENCE; CONTROLLED STUDY; GERM LINE; PHAGE DISPLAY; PRIORITY JOURNAL; PROTEIN DOMAIN; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 0030770938     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/10.7.835     Document Type: Article

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