Sequence analysis and bacterial production of the anti-c-myc antibody 9E10: The V(H) domain has an extended CDR-H3 and exhibits unusual solubility

FEBS Letters

Volumn 414, Issue 1, 1997, Pages 33-38

  Schiweck, Wolfram ^a   Buxbaum, Britta ^a   Schätzlein, Christian ^a   Neiss, Hans Günther ^a   Skerra, Arne ^a  

^a DARMSTADT UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Antibody engineering; E. coli secretion; F(ab) fragment; Immunoglobulin; Myc tag

Indexed keywords

ANTIBODY; CHIMERIC PROTEIN; IMMUNOGLOBULIN F(AB) FRAGMENT; RECOMBINANT PROTEIN;

ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; MOLECULAR CLONING; ONCOGENE C MYC; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; TECHNIQUE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; BASE SEQUENCE; CLONING, MOLECULAR; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENES, IMMUNOGLOBULIN; HISTIDINE; HYBRIDOMAS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MICE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PEPTIDES; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS C-MYC; RECOMBINANT FUSION PROTEINS; SEQUENCE ANALYSIS; SOLUBILITY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 0030768687     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(97)00983-6     Document Type: Article

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