Detailed microsatellite analysis of chromosome 3p region in non- papillary renal cell carcinomas

International Journal of Cancer

Volumn 73, Issue 2, 1997, Pages 225-229

  Chudek, Jerzy ^a   Wilhelm, Monica ^a   Bugert, Peter ^a   Herbers, Jutta ^a   Kovacs, Gyula ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MICROSATELLITE DNA;

ARTICLE; CHROMOSOME 3P; CHROMOSOME ANALYSIS; GENE DELETION; GENE LOCUS; GENE MAPPING; HUMAN; HUMAN TISSUE; KIDNEY CARCINOMA; PRIORITY JOURNAL;

CARCINOMA, RENAL CELL; CHROMOSOME DELETION; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 3; DNA PRIMERS; DNA, NEOPLASM; HUMANS; KIDNEY NEOPLASMS; LOSS OF HETEROZYGOSITY; MICROSATELLITE REPEATS; MUTATION;

EID: 0030768425     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19971009)73:2<225::AID-IJC11>3.0.CO;2-E     Document Type: Article

References (25)

1. BUGERT, P. and KOVACS, G., Molecular differential diagnosis of renal cell carcinomas by microsatellite analysis. Amer. J. Patho., 149, 2081-2088 (1996).
2. BUGERT, P., KENCK, C. WILHELM, M. and KOVACS, G., Refining a proximal breakpoint cluster at chromosome 3p11.2 in non-papillary renal cell carcinomas. Int. J. Cancer, 68, 723-726 (1996).
3. BUGERT, P., WILHELM, M. and KOVACS, G., FHIT gene and the FRA3B region are not involved in the genetics of renal cell carcinomas. Genes Chromosomes Cancer (1997) (In press).
4. CROSSEY, P.A. and 16 OTHERS. Molecular genetic investigations of the mechanism of tumorigenesis in von Hippel-Lindau disease: analysis of allele loss in VHL tumours. Hum. Genet., 93, 53-58 (1994).
5. ERLANDSSON, R., BOLBOG, F., PERSSON, B., ZABAROVSKY, E.R., ALLIKMETS, R.L., SÜMEGI, J., KLEIN, G. and JÖRNVALL. H., The gene from the short arm of chromosome 3. at D3F15S2. frequently deleted in renal cell carcinoma encodes acylpeptide hydrolase. Oncogene, 6, 1293-1295 (1991).
6. FOSTER, K., CROSSEY, P.A., CAIRNS, P., HETHERINGTON, J.W., RICHARDS, F.M., JONES, M.H., BENTLEY, E., AFFARA, N.A., FERGUSON-SMITH, M.A. and MAHER, E.R., Molecular genetic investigation of sporadic renal cell carcinoma: analysis of allele loss on chromosomes 3p, 5q, 11p, 17 and 22. Brit. J. Cancer, 69, 230-234 (1994).
7. GNARRA, J.R. and 23 OTHERS, Mutations of the VHL tumour suppressor gene in renal carcinoma. Nature (Genet.), 7, 85-89 (1994).
8. KENCK, C., WILHELM, M., BUGERT, P., STAEHLER, G. and KOVACS, G., Mutation of the VHL gene is associated exclusively with the development of non-papillary renal cell carcinomas. J. Pathol., 179, 157-161 (1996).
9. KOK, K., HOFSTRA, R., PlLZ, A., VAN DEN BERG, A., TERPSTRA, P., BUYS, C.H.C.M. and CARRITT, B., A gene in the chromosomal region 3p2l with greatly reduced expression in lung cancer is similar to the gene for ubiquitin-activating enzyme. Proc. nat. Acad. Sci. (Wash.), 90, 6071-6075 (1993).
10. KOVACS, G., Molecular cytogenetics of renal cell tumors. Adv. Cancer Res., 62, 89-124 (1993).
11. KOVACS, G. and FRISCH, S., Clonal chromosome abnormalities in tumor cells from patients with sporadic renal cell carcinomas. Cancer Res., 49, 651-659 (1989).
12. KOVACS, G. and KUNG, H., Nonhomologous chromatid exchange in hereditary and sporadic renal cell carcinoma. Proc. nat. Acaa. Sci. (Wash.), 88, 194-198 (1991).
13. LAFORGIA, S. and 15 OTHERS, Receptor protein-tyrosine phosphatase γ is a candidate tumor suppressor gene at human chromosome region 3p21. Proc. nat. Acad. Sci. (Wash. ), 88, 5036-5040 (1991).
14. LATIF, F. and 32 OTHERS. Identification of the von Hippel-Lindau disease tumor suppressor gene. Science, 260, 1317-1320 (1993).
15. LISITSYN, N.A., LISITSINA, N.M., DALBAGNI, G., BARKER, P., SANCHEZ, C.A., GNA RRA, J., LINEHAN, W.M., REID, B.J. and WIGLER, M.H., Comparative genomic analysis of tumors: Detection of DNA losses and amplification. Proc. nat. Acad. Sci. (Wash.), 92, 151-155 (1995).
16. LUBINSKI, J., HADACZEK, P., PODOLSKI, J., TOLOCZKO, A., SIKORSKI, A., McCUE, P., DRUCK, T. and HUEBNER, K., Common regions of deletion in chromosome regions 3pl2 and 3pl4.2 in primary clear cell renal cell carcinomas. Cancer Res., 54, 3710-3713 (1994).
17. OHTA, M., INOUE, H., COTTICELLI, M.G., KASTURY, K., BAFFA, R., PALAZZO, J., SIPRASHVILI, Z., MORI, M., MCCUE, P., DRUCK, T., CROCE, C.M. and HUEBNER, K., The FHITgene. spanning the chromosome 3pl4.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell, 84, 587-597 (1996).
18. SANCHEZ, Y., EL-NAGGAR, A., PATHAK, S. and MCNEILL, K.A.A., Tumor suppressor locus within 3pl4-pl2 mediates rapid cell death of renal cell carcinoma in vivo. Proc. nat. Acad. Sci. (Wash.), 91, 3383-3387 (1994).
19. SHIMIZU, M., YOKOTA, J., MORI, N., SHUIN, T., SHINODA, M., TERADA, M. and OSHIMURA, M., Introduction of normal chromosome 3p modulates the tumorigenicity of a human renal cell carcinoma cell line YCR. Oncogene, 5, 185-194 (1990).
20. SHRIDHAR, V., RIVARD, S., SHRIDHAR, R., MULLINS, C., BOSTICK, L., SAKR, W., GRIGNON, D., MILLER, O.J. and SMITH, D.I., A gene from human chromosomal band 3p21.1 encodes a highly conserved arginin-rich protein and is mutated in renal cell carcinomas. Oncogene, 12, 1913-1939 (1996).
21. SMITH, D.I., GLOVER, T.W., GEMMILL, R., DRABKIN, H., O'CONNELL, P. and NAYLOR, S.L., Report of the fifth international workshop on human 3 mapping 1994. Cytogenet. Cell Genet., 68, 126-136 (1995).
22. VAN DEN BERG, A., HULSBEEK, M.M.F. DE JONG, D., KOK, K., VELDHUIS, P.M.J.F. ROCHE, J. and BUYS, C.H.C.M., Major role for a 3p21 region and lack of involvement of the t(3;8) breakpoint region in the development of renal cell carcinoma suggested by loss of heterozygosity analysis. Genes Chromosomes Cancer. 15, 64-72 (1996).
23. VAN DER HOUT, A., VAN DER VLIES, P., WIJMENGA, C., Ll, P.P., OOSTERHUIS, J.W. and BUYS, C.H.C.M., The region of common allelic losses in sporadic renal cell carcinoma is bordered by the loci D3S2 and THRB. Genomics, 11, 537-542 (1991).
24. WILHELM, M., BUGERT, P., KENCK, C., STAEHLER, G. and KOVACS, G., Terminal deletion of chromosome 3p sequences in nonpapillary renal cell carcinomas: a breakpoint cluster between loci D3S1285 and D3S1603. Cancer Res., 55, 5383-5385 (1995).
25. YAMAKAWA, K., MORITA, R., TAKAHASHI, E., HORI, T., ISHIKAWA, J. and NAKAMURA, Y., A detailed mapping of the short arm of chromosome 3 in sporadic renal cell carcinoma. Cancer Res., 51, 4707-4711 (1991).