Host response

Current Opinion in Gastroenterology

Volumn 13, Issue SUPPL. 1, 1997, Pages 25-30

  Bamford, K B ^a,b,d   Andersen, L ^c  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b ROYAL GROUP OF HOSPITALS TRUST   (United Kingdom)

^c Rigshospitalet   (Denmark)

^d ROYAL VICTORIA HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY;

ANTIBODY RESPONSE; CELL INTERACTION; CELLULAR IMMUNITY; EPITHELIUM CELL; HELICOBACTER PYLORI; HUMAN; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; NEUTROPHIL; OXIDATION; SHORT SURVEY; STOMACH ACID SECRETION; STOMACH MUCOSA;

EID: 0030760231     PISSN: 02671379     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (70)

1. Hamlet A, Olbe L: The influence of Helicobacter pylori infection on postprandial duodenal acid load and duodenal bulb pH. Gastroenterology 1996, 111:391-400.
2. Hogan LM, Rapier RC, Dreilinger A, Koss MA, Basuk PM, Weinstein WM, Nyberg LM, Isenberg JI: Duodenal bicarbonate secretion - eradication of Helicobacter pylori and duodenal structure and function in humans. Gastroenterology 1996, 110:705-716. Describes the correlation of duodenal bicarbonate production with ulceration.
3. Savarino V, Mela GS, Zentilin P, Mele MR, Lapertosa L, Patella R, Dalloroto E, Vassallo A, Mansi C, Vigneri S, Celle G: Orcadian gastric acidity in Helicobacter pylori positive ulcer patients with and without gastric metaplasia in the duodenum. Gut 1996, 39:508-512.
4. Harris AW, Gummett PA, Walker MM, Misiewicz JJ, Baron JH: Relation between gastric acid output, Helicobacter pylori, and gastric metaplasia in the duodenal bulb. Gut 1996, 39:513-520.
5. Weber HC, Venzon DJ, Jensen RT, Metz DC: Studies on the interrelation between Zollinger-Ellison syndrome, Helicobacter pylori, and proton pump inhibitor therapy. Gastroenterology 1997, 112:84-91.
6. Meyer-Rosberg K, Scott DR, Rex D, Melchers K, Sachs G: The effect of environmental pH on the proton motive force of Helicobacter pylori. Gastroenterology 1996, 111:886-900.
7. Shibata T, Imoto I, Taguchi Y, Takaji S, Ikemura N, Nakao K, Koshiyama M, Shima T: High acid secretion may protect the gastric mucosa from injury caused by ammonia produced by Helicobacter pylori in duodenal ulcer patients. Gastroenterol Hepatol 1996, 11:674-680.
8. McColl KEL: Helicobacter pylori, gastric acid, and duodenal gastric metaplasia. Gut 1996, 39:615-616.
9. Sipponen P, Kekki M, Seppala K, Siurala M: The relationships between chronic gastritis and acid secretion. Alimen Pharmacol Ther 1996, 10(Suppl 1): 103-118.
10. Satoh K, Kimura K, Taniguchi Y, Yoshida Y, Kihira K, Takimoto T, Kawata H, Saifuku K, Ido K, Takemoto T et al. : Distribution of inflammation and atrophy in the stomach of Helicobacter pylori-positive and Helicobacter pylori-negative patients with chronic gastritis. Am J Gastroenterol 1996, 91:963-969.
11. Courillon-Mallet A, Launay JM, Roucaryrol AM, Callebert J, Edmond JP, Tabuteau F et al.: Helicobacter pylori infection: pathophysiological implication of Nα-methyl-histamine. Gastroenterology 1995, 108:956-966.
12. Beales ILP, Calam J: Effect of N alpha-methyl-histamine on acid secretion in isolated cultured rabbit parietal cells: implications for Helicobacter pylori associated gastritis and gastric physiology. Gut 1997, 40:14-19.
13. Valenzuela M, Martin-Ruiz JL, Caballero-Plasencia AM, Alvarez-Cienfuegos I, Nogales FF, Guilarte J, Pena JF: Parietal cell hyperactivity is not due to Helicobacter pylori infection in patients with duodenal ulcer. Am J Gastroenterol 1996, 91:2114-2119 The lack of relation of acid production at the cellular level to H. pylori.
14. Bechi P, Romagnoli P, Bacci S, Dei R, Amorosi A, Cianchi F, Masini E: Helicobacter pylori and duodenal ulcer: evidence for a histamine pathways-involving link. Am J Gastroenterol 1996, 91:2338-2343. An important review of the role of histamine pathways including the effect of H. pylori.
15. Beales I, Calam J, Post L, Srinivasan S, Yamada T, DelValle J: Effect of transforming growth factorα and interleukin 8 on somatostatin release from canine fundic D cells. Gastroenterology 1997, 112:136-143. Two groups [15••, 16•] investigated the interrelationship between the immune and local endocrine system in terms of gastrin and somatostatin production using a canine model.
16. Lehmann FS, Golodner EH, Wang JY, Chen MCY, Avedian D, Calam J, Walsh JH, Dubinett S, Soll AH: Mononuclear cells and cytokines stimulate gastrin release from canine antral cells in primary culture. Am J Physiol Gastro Liver Physiol 1996, 33:G783-G788. See [15••].
17. Yasunaga Y, Shinomura Y, Kanayama S, Higashimoto Y, Yabu M, Miyazaki Y, Kondo S, Murayama Y, Nishibayashi H, Kitamura S, Matsuzawa Y: Increased production of interleukin 1β and hepatocyte growth factor may contribute to foveolar hyperplasia in enlarged fold gastritis. Gut 1996, 39:787-794.
18. Prinz C, Neumayer N, Mahr S, Classen M, Schepp W: Functional impairment of rat enterochromaffin-like cells by interleukin 1β. Gastroenterology 1997, 112:364-375.
19. Kurose I, Granger DN, Evans DJ, Evans DG, Graham DY, Miyasaka M, Anderson DC, Wolf RE, Cepinskas G, Kvietys PR: Helicobacter pylori-induced microvascular protein leakage in rats: role of neutrophils, mast cells and platelets. Gastroenterology 1994, 107:70-79.
20. Takemura T, Granger DN, Evans DG, Evans DJ, Graham DY, Anderson DC, Wolf RE, Cepinskas G, Kvietys PR: Extract of Helicobacter pylori induces neutrophils to injure endothelial cells and contains antielastase. Gastroenterology 1996, 110:21-29. Direct evidence that H. pylori activated neutrophils damage endothelial cells.
21. Yamakoa Y, Kita M, Kodama T, Sawai N, Imanishi J: Helicobacter pylori cagA gene expression of cytokine messenger RNA in gastric mucosa. Gastroenterology 1996, 110:1744-1752.
22. Ando T, Kusugami K, Oshuga M, Shinoda M, Sakakibara M, Saito H, Fukatsu A, Ichiyama S, Ohta M: Interleukin-8 activity correlates with histological severity in Helicobacter pylori-associated antral gastritis. Am J Gastroenterol 1996, 91:1150-1156.
23. Crabtree JE: Gastric mucosal inflammatory responses to Helicobacter pylori. Alimen Pharmacol Ther 1996, 10(Suppl 1):29-37. Very good overview of the inflammatory response to H. pylori.
24. Zhang QB, Nakshabendi IM, Mokhashi MS, Dawodu JB, Gemmell CG, Russell RI: Association of cytotoxin production and neutrophil activation by strains of Helicobacter pylori isolated from patients with peptic ulceration and chronic gastritis. Gut 1996, 38:841-845.
25. Crabtree JE: Immune and inflammatory responses to Helicobacter pylori infection. Scand J Gastroenterol 1996, 31 (Suppl 215 515):3-10.
26. Rautelin H, Sipponen P, Seppala K, Sarna S, Danielsson D, Kosunen TU: Gastric inflammation and neutrophil-activating and cytotoxin-producing Helicobacter pylori strains. Scand J Gastroenterol 1996, 31:639-642.
27. Sasayama Y, Kawano S, Tsuji S, Fusamoto H, Kamada T, Fukui H, Yoneda S, Okishio T: Relationship between interleukin-8 levels and myeloperoxidase activity in human gastric mucosa. J Gastroenterol Hepatol 1997, 12:104-108.
28. Farinati F, Libera GD, Cardin R, Molari A, Plebani M, Rugge M, Di Mario F, Naccarato R: Gastric antioxidant, nitrites, and mucosal lipoperoxidation in chronic gastritis and Helicobacfer pylori infection. J Clin Gastroenterol 1996, 22:275-281. Correlates H. pylori infection with increased free radical and decreased antioxidant levels in the gastric mucosa.
29. Phull PS, Price AB, Thorniley MS, Green CJ, Jacyna MR: Vitamin E concentrations in the human stomach and duodenum-correlation with Helicobacter pylori infection. Gut 1996, 39:31-35. Further evidence of reduced antioxidant levels.
30. Broide E, Klinowski E, Varsano R, Eshchar J, Herbert M, Scapa E: Superoxide dismutase activity in Helicobacter pylori-positive antral gastritis in children. J Pediat Gastroenterol Nutr 1996, 23:609-613.
31. Gotz JM, van Kan CI, Verspaget HW, Biemond I, Lamers CBHW, Veenendaal RAV: Gastric mucosal superoxide dismutases in Hellicobacter pylori infection. Gut 1996, 38:502-506.
32. Klinowski E, Broide E, Varsano R, Eshchar J, Scapa E: Superoxide dismutase activity in duodenal ulcer patients. Eur J Gastroenterol Hepatol 1996, 8:1151-1155.
33. Bode C, Maute G, Bode JC: Prostaglandin E2 and prostaglandin F2-alpha biosynthesis in human gastric mucosa: effect of chronic alcohol misuse. Gut 1996, 39:348-352.
34. Wilson KT, Ramanujam KS, Mobley HLT, Musselman RF, James SP, Meltzer SJ: Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line. Gastroenterology 1996, 111:524-533. Investigates the cellular production of nitric oxide synthesis in response to H. pylori.
35. Shapiro KB, Hotchkiss JH: Induction of nitric oxide synthesis in murine macrophages by Helicobacter pylori. Cancer Lett 1996, 102:49-56.
36. Norgaard A, Andersen LP, Elsborg L, Holck S, Nielsen H: Specific neutrophil hyporesponsiveness in chronic Helicobacter pylori infection. J Infect Dis 1996, 174:544-551. Important description of specific neutrophil response to homologous isolates of H. pylori.
37. Smoot DT, Resau JH, Earlington MH, Simpson M, Cover TL: Effects of Helicobacter pylori vacuolating cytotoxin on primary cultures of human gastric epithelial cells. Gut 1996, 39:795-799.
38. Bechi P, Balzi M, Beccioloni A, Maugeri A, Raggi CC, Amorosi A, Dei R: Helicobacter pylori and cell proliferation of the gastric mucosa: Possible implications for gastric carcinogenesis. Am J Gastroenterol 1996, 91:271-276.
39. Marcinkiewicz M, Van der Linden B, Peura DA, Goldin G, Parolisi S, Sarosiek J: Impact of Helicobacter pylori colonisation on immunoreactive epidermal growth factor and transforming growth factor-α in gastric juice. Dig Dis Sci 1996, 41:2150-2155.
40. Moss SF, Calam J, Agarwal B, Wang S, Holt PR: Induction of gastric epithelial cell apoptosis by Helicobacter pylori. Gut 1996, 38:498-501. Demonstration of gastric mucosal cell apoptosis using the terminal dYTP nick end labelling assay with consideration of the effect on cell turnover.
41. Ricci V, Ciacci C, Zarrilli R, Sommi P, Tummuru MKR, Blanco CD, Bruni CB, Cover TL, Blaser MJ, Romano M: Effect of Helicobacter pylori on gastric epithelial cell migration and proliferation in vitro-role of vacA and Cag A. Infect Immun 1996, 64:2829-2833.
42. Kodama R, Fujioka T, Shuto R, Kubota T, Nasu M: Helicobacter pylori infection delays the healing of acetic acid-induced gastric ulcer in Japanese monkeys, J Gastroenterol Hepatol 1996, 11:1097-1102.
43. Eliakim R, Alpers DH, Oren R, Fich A, Deschryverkecskemeti K: Abundance of surfactant like particles reflects mucosal integrity in patients with peptic ulcer disease. Gut 1996, 39:353-359.
44. Sakagami T, Dixon M, O'Rourke J, Howlett R, Alderuccio F, Vella J, Shimoyama T, Lee A: Atrophic gastric changes in both Helicobacter felis and Helicobacter pylori infected mice are host dependent and separate from antral gastritis. Gut 1996, 39:639-648.
45. Mohammadi M, Redline R, Nedrud J, Czinn S: Role of the host in pathogenesis of Helicobacter-associaied gastritis: H. felis infection of inbred and congenic mouse strains. Infect Immun 1996, 64:238-245. Evidence from an animal model for the importance of the hosts genetic background and host factors in the pathogenesis of H. pylori related pathology.
46. Georgopoulos SD, Mentis AF, Spiliadis CA, Tzouvelekis LS, Tzelepi E, Moshopoulos A, Skandalis N: Helicobacter pylori infection in spouses of patients with duodenal ulcers and comparison of ribosomal RNA gene patterns. Gut 1996, 39:634-638.
47. Parente F, Maconi G, Sangaletti O, Minguzzi M, Vago L, Rossi E, Banchi Porro GB: Prevalence of Helicobacter pylori infection and related gastroduodenal lesions in spouses of Helicobacter pylori positive patients with duodenal ulcer. Gut 1996, 39:629-633.
48. Atherton JC, Peek RM, Tham KT, Cover TL, Blaser MJ: Clinical and pathological importance of heterogeneity in vacA, the vacuolating cytotoxin gene of Helicobacter pylori. Gastroenterology 1997, 112:92-99.
49. Chimiela M, Czkwianianc E, Wadstrom T, Rudnicka W: Role of Helicobacter pylori surface structures in bacterial interaction with macrophages. Gut 1997, 40:20-24.
50. Harris PR, Mobley HLT, Perez-perez GI, Blaser MJ, Smith PD: Helicobacter pylori urease is a potent stimulus of monunuclear phagocyte activation and inflammatory cytokine production. Gastraenterology 1996, 111:419-425. Urease is a candidate vaccine. This paper studies the effect it has on antigen presenting cells and describes its ability to induce cytokine production.
51. Basso D, Scrigner M, Toma A, Navaglia F, Dimario F, Rugge M, Plebani M: Helicobacter pylori infection enhances mucosal interleukin-1-beta, interleukin-6, and the soluble receptor of interleukin-2. Int J Clin Lab Res 1996, 26:207-210.
52. Karttunen TJ, Niemela S, Kerola T: Blood leukocyte differential in Helicobacter pylori infection. Dig Dis Sci 1996, 41:1332-1336.
53. Ernst PB, Crowe SE, Reyes VE: The immunopathogenesis of gastroduodenal disease-associated with Helicobacter pylori infection. Curr Opin Gastroenterol 1995, 11:512-518.
54. Ihan A, Tepez B, Kavcic T, Gubina M: IL-2 receptor expression on gastric mucosa T lymphocytes is enhanced in duodenal ulcer patients compared with non-ulcer dyspeptic patients. Hepatogastroenterol 1996, 43:1665-1670. Describes increased markers of T-cell activation in ulcer compared with non-ulcer patients with H. pylori infection.
55. Ishihara S, Fukuda R, Fukumoto S: Cytokine gene expression in the gastric mucose • its role in chronic gastritis. J Gastroenterol 1996, 31:485-490.
56. D'Elios MM, Manghetti M, De Carli M, Costa F, Baldari CT, Burroni D, Telford JL, Romagnani S, Del Prete G: T Helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease. J Immunol 1997, 158:962-967. Important description of T-cell responses using clones developed from the gastric mucosa.
57. Fan XG, Yakoob J, Fan XJ, Keeling PWN: Enhanced T-helper 2 lymphocyte responses - immune mechanism of Helicobacter pylori infection. Ir J Med Sci 1996, 165:37-39.
58. Mohammadi M, Czinn S, Redline R, Nedrud J: Helicobacter-specific cell-mediated immune responses display a predominant Th1 phenotype and promote a delayed type hypersensitivity response in the stomachs of mice. J Immunol 1996, 156:4729-4738. Definition of T-cell subset responses in a mouse model.
59. Karttunen RA, Karttunen TJ, Yousfi MM, El-Zimaity HMT, Graham DY, El-Zaatari FAK: Expression of mRNA for interferon-gamma, interleukin-10, and interleukin-12 (p40) in normal gastric mucosa and in mucosa infected with Helicobacter pylori. Scand J Gastroenterol 1997, 32:22-27. Measurement of cytokines related to T-helper subset development.
60. Cuenca R, Blanchard TG, Czinn SJ, Nedrud JG, Monath TP, Lee CK, Redline RW: Therapeutic immunization against Helicobacter mustelae in naturally infected ferrets. Gastroenterology 1996, 110:1770-1775.
61. Fiorucci S, Santucci L, Migliorati G, Riccardi C, Amorosi A, Mancini A, Roberti R, Morelli A: Isolated guinea pig gastric chief cells express tumor necrosis factor receptors coupled with the sphingomyelin pathway. Gut 1996, 38:182-189. Further evidence of the link between gastric mucosal physiology and cytokine production.
62. Kuipers EJ, Pals G, Pena AS, Vanuffelen CWJ, Kok A, Westerveld BD, Meuwissen SGM: Helicobacter pylori pepsinogens and gastrin-relationship with age and development of atrophic gastritis. Eur J Gastroenterol Hepatol 1996, 8:153-156.
63. Chang C-S, Chen G-H, Kao C-H, Wang S-J, Peng S-N, Huang C-K: The effect of Helicobacter pylori infection on gastric emptying of digestible and indigestible solids in patients with nonulcer dyspepsia. Am J Gastroenterol 1996, 91:474-479.
64. Holtmann G, Talley NJ, Goebell H: Association between H. pylori, duodenal mechanosensory thresholds, and small intestinal motility in chronic unexplained dyspepsia. Dig Dis Sci 1996, 41:1285-1291.
65. Acbay O, Celik AF, Gundogdu S: Does Helicobacter pylori-induced gastritis enhance food-stimulated insulin release? Dig Dis Sci 1996, 41:1327-1331.
66. Gotz JM, Vergouwe Y, Verspaget HW, Biemond I, Sier CFM, Lamers CBHW, Veenendaal RA: Gastric mucosla plasminogen activators in Helicobacter pylori infection. Dig Dis Sci 1996, 41:1577-1582.
67. Graham DY, Genta RM, Graham DP, Crabtree JE: Serum cag A antibodies in asymptomatic subjects and patients with peptic ulcer - lack of correlation of IgG antibody in patients with peptic ulcer or asymptomatic Helicobacter pylori gastritis. J Clin Pathol 1996, 49:829-832.
68. Mitchell HM, Hazell SL, Kolesnikow T, Mitchell J, Frommer D: Antigen recognition during progression from acute to chronic infection with a cag A-positive strain of Helicobacter pylori. Infect Immun 1996, 64:1166-1172. Interesting description of changes in antigen recognition during the course of infection with H. pylori.
69. Berstad AE, Brandtzaeg P, Stave R, Halstensen TS: Epithelium related deposition of activated complement in Helicobacter pylori associated gastritis. Gut 1997, 40:196-203.
70. Demonstration of deposition of activated complement in the infected gastric mucosa and implications for tissue damage. Current Opinion in Gastroenterology 1997, 13:31-34