Enhanced T-helper 2 lymphocyte responses: Immune mechanism of helicobacter pylori infection (minireview)

Irish Journal of Medical Science

Volumn 165, Issue 1, 1996, Pages 37-39

  Fan, X G ^a   Yakoob, J ^a   Fan, X J ^a   Keeling, P W N ^a  

^a ST JAMES S HOSPITAL   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6;

ANIMAL CELL; ARTICLE; BACTERIAL COLONIZATION; CELL PROLIFERATION; GRAM NEGATIVE INFECTION; HELICOBACTER PYLORI; HELPER CELL; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOPATHOGENESIS; MOUSE; NONHUMAN; PATHOGENESIS;

CHRONIC DISEASE; GASTROINTESTINAL DISEASES; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; INTERFERON-ALPHA; INTERLEUKIN-2; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 0029972845     PISSN: 00211265     EISSN: None     Source Type: Journal    
DOI: 10.1007/bf02942800     Document Type: Article

References (30)

1. Blaser, M. J. Helicobacter pylori: microbiology of a 'slow' bacterial infection. Trends in Microbiology 1993; 1: 255-60.
2. Marshall, B. J. Helicobacter pylori. Am. J. Gastroenterol. 1994; 89: s116-28.
3. Personnet, J. Helicobacter pylori and gastric cancer. Gastrenterol Clin. North Am. 1993; 22: 89-104.
4. Blaser, M. J. Hypotheses on the pathogenesis and natural history of Helicobacter pylori-induced inflammation. Gastroenterology 1992; 102: 720-7.
5. Moss, S., Calam, J. Helicobacter pylori and peptic ulcers: the present position. Gut 1992; 33: 289-92.
6. Fan, X. G., Chua, A., Fan, X. J., Keeling, P. W. N. Lipid peroxidation induced by Helicobacter pylori. Exp. Clin. Gastroenterol. 1994; 4: 29-340.
7. Ernst, P. B., Navarro, J. J., Reyes, V., Crowe, S. Overview of the immune response to H. pylori. In R. H. Hunt, G. N. T. Tytgat (eds): Helicobacter pylori: Basic mechanisms to clinical cure. Kluwer Academic Publishers. Lancaster, U.K., 1994: 295-305.
8. Mosmann, T. R., Cherwtnski, H. Bond, M. W., Giedlin, M. A., Coffman, R. I. Two types of murine helper T cell clones. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 1986; 136: 2348-57.
9. Fiorentino, D. F., Bond, M. W., Mosmann, T. R. Two types of mouse T helper cell IV: Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J. Exp. Med. 19891 70 :208198.
10. Martinez, O. M., Gibbons, R. S., Garovoy, M. R., Aronson, F. R. IL-4 inhibits IL-2 receptor expression and IL-2-dependent proliferation of human T cells. J. Immunol. 1990; 144: 2211-5.
11. Howard, M., O'Garra, A. Biological properties of interleukin 10. Immunol. Today 1992; 13: 198-200.
12. Modlin, R. L., Nutman, T. B. Type 2 cytokines and negative immune regulation in human infections. Curr. Opin. in Immunology 1993; 5: 511-7.
13. Clerici, M., Shearer, G. M. ATH1-TH2 switch is a critical step in the etiology of HIV infection. Immunol. Today 1993; 14: 107-11.
14. Croitoru, K. Down-regulation of the immune response to H. pylori. In R. H. Hunt, G. N. T. Tytgat (eds): Helicobacter pylori: Basic mechanisms to clinical cure. Kluwer Academic Publishers. Lancaster, U.K.. 1994: 333-341.
15. Blaser, M. J., Parsonnet, J. Parasitism by the slow bacterium Helicobacter pylori leads to altered gastric homeostasis and neoplasia. J. Clin. Invest. 994; 94 :4-8.
16. Karttunen, R., Andersson, G., Poikonen, K., Kosunen, T. U., Karttunen, T., Juutinen, K. Helicobacter pylori induces lymphocyte activation in peripheral blood cultures. Clin. Exp. Immunol. 1990; 82: 485-8.
17. Fan, X. J., Chua, A., Shahi, C. N, McDevitt, J., Keeling, P. W. N., Kelleher, D. Gastric T lymphocyte responses to Helicobacter pylori in patients with H. pylori colonisation. Gut 1994; 35: 1379-84.
18. Fan, X. G., Yakoob, J., Fan, X. J., Kelleher, D., Keeling, P. W. N. Cytokine production in patients with H. pylori infection. I. J. Med. Sci. 1994; 163: 582.
19. Crabtree, J. E., Shallcross, T. M., Heatley, R. V, Wyatt, J. I. Mucosal tumour necrosis factor a and interleukin-6 in patients with Helicobacter pylori associated gastritis. Gut 1991; 32: 1473-7.
20. Vercelli, D., Jabara, H. H., Lauener, R. P., Geha, R. S. IL-4 inhibits the synthesis of IFN-γ and induces the synthesis of IgE in human mixed lymphocyte cultures. J. Immunol. 1990; 144: 570-8.
21. Danzer, S. G., Kirchner, H., Rink, L. Cytokine interactions in Human mixed lymphocyte culture. Transplantation 1994; 57: 1638-42.
22. Marchant, A., Bruyns, C., Vandenabeele, P., Ducarme, M., Gerard, C., Delvaux, A. et al. Interleukin-10 controls interferon-Y and tumor necrosis factor production during experimental endotoxemia. Eur. J. Immunol. 1994; 24: 1167-71.
23. Sieling, P. A., Abrams, J. S., Yamamura, M., Salgame, P., Bloom, B. R., Rea, T. H. et al. Immunosuppressive roles for IL-10 and IL-4 in human infection. In vitro modulation of T cell responses in Leprosy. J. Immunol. 1993; 150: 5501-10.
24. Karttunen, R. Blood lymphocyte proliferation, cytokine secretion and appearance of T cells with activation surface markers in cultures with Helicobacter pylori. Comparison of the responses of subjects with and without antibodies to H. pylori. Clin. Exp. Immuno. 1 1991; 83: 396-400.
25. Newell, D. G., Stacey, A. R. B cell responses in H. pylori infection. In R. H. Hunt, G. N. T .Tytgat (eds: Helicobacter pylori: Basic mechanisms to clinical cure. Kluwer Academic Publishers. Lancaster, U.K., 1994: 309-320.
26. Tytgat, G. N. J., Lee, A, Graham, D. Y., Dixon, M. F., Rokkas, T. The role of infectious agents in peptic ulcer disease. Gastroenterol international 1993; 6: 76-89.
27. Peura, D. A., Graham, D. Y. Helicobacter pylori: consensus reached: peptic ulcer is on the way to becoming an historic disease. Am. J. Gastroenterol. 1994; 89: 1137-9.
28. Trinchieri, G. Interleukin-12 and its role in the generation of TH1 cells. Immunol today 1993; 14: 335-7.
29. Ho, A. S. Y., Moore, K. W. Interleukin-10 and its receptor. Therapeutic Immunol 1994; 1: 173-85.
30. Gately, M. K., Gubler, U., Brunda, M. J., Nadeau, R. R., Anderson, T. D., Lipman, J. M., Sarmiento, U. Interleukin-12: a cytokine with therapeutic potential in oncology and infectious diseases. Therapeutic Immunol. 1994; 1: 187-96.