Notch signalling in development: On equivalence groups and asymmetric developmental potential

Current Opinion in Genetics and Development

Volumn 7, Issue 4, 1997, Pages 537-542

  Simpson, Pat ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DEVELOPMENTAL GENETICS; DROSOPHILA; NERVOUS SYSTEM DEVELOPMENT; NEUROECTODERM; NONHUMAN; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; STATISTICS;

EID: 0030758464     PISSN: 0959437X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-437X(97)80083-4     Document Type: Article

References (47)

1. Gurdon JB. The generation of diversity and pattern in animal development. Cell. 68:1992;185-199.
2. Greenwald I, Rubin GM. Making a difference: the role of cell - cell interactions in establishing separate identities for equivalent cells. Cell. 68:1992;271-281.
3. Simpson P. The Notch receptors. 1994;RG Landes Company, Austin, TX.
4. Artavanis-Tsakonas S, Matsuno K, Fortini M. Notch signalling. Science. 268:1995;225-232.
5. Kimble J, Simpson P. The Lin12/Notch signalling pathway and its regulation. Annu Rev Cell Biol. 1997;. in press.
6. Chitnis A, Henrique D, Lewis J, Ish-Horowicz D, Kintner C. Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature. 375:1995;761-766.
7. Lewis J. Neurogenic genes and vertebrate neurogenesis. Curr Opin Neurobiol. 6:1996;3-10.
8. Park AI, Huppert S, Muskavitch MAT. The dynamics of neurogenic signalling underlying bristle development in Drosophila melanogaster. Mech Dev. 63:1997;61-74.
9. Ghysen A, Dambly-Chaudire C. From DNA to form: the achaete - scute complex. Genes Dev. 2:1988;495-501.
10. Villares R, Cabrera C. The achaete - scute gene complex of D. melanogaster: conserved domains in a subset of genes required for neurogenesis and their homology to myc. Cell. 50:1987;415-424.
11. Fehon RG, Johansen K, Rebay I, Arlavanis-Tsakonas S. Complex cellular and subcellular regulation of Notch expression during embryonic and imaginal development of Drosophila: implications for Notch function. J Cell Biol. 113:1991;657-669.
12. Kooh PJ, Fehon RG, Muskavitch MAT. Implications of dynamic patterns of Delta and Notch expression for cellular interactions during Drosophila development. Development. 117:1993;493-507.
13. Heitzler P, Simpson P. The choice of cell fate in the epidermis of Drosophila. Cell. 64:1991;1083-1092.
14. Hartenstein V, Posakony JW. A dual function of the Notch gene in Drosophila sensillum development. Dev Biol. 142:1990;13-30.
15. Lieber T, Kidd S, Alcamo E, Corbin V, Young M. Antineurogenic phenotypes induced by truncated Notch proteins indicate a role in signal transduction and may point to a novel function for Notch in nuclei. Genes Dev. 7:1993;1949-1965.
16. Rebay I, Fehon R, Artavanis-Tsakonas S. Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor. Cell. 74:1993;319-329.
17. Struhl G, Fitzgerald K, Greenwald I. Intrinsic activity of the lin-12 and Notch intracellular domains in vivo. Cell. 74:1993;331-345.
18. Bailey AM, Posakony JW. Suppressor of Hairless directly activates transcription of Enhancer of split Complex genes in response to Notch receptor activity. Genes Dev. 9:1995;2609-2622.
19. Lecourtois M, Schweisguth F. The neurogenic Suppressor of hairless DNA-binding protein mediates the transcriptional activation of Enhancer of split complex genes triggered by Notch signalling. Genes Dev. 9:1995;2598-2608.
20. Oellers N, Dehio M, Knust E. bHLH proteins encoded by the Enhancer of split complex of Drosophila negatively interfere with transcriptional activation mediated by proneural genes. Mol Gen Genet. 244:1994;465-473.
21. Heitzler P, Simpson P. Altered epidermal growth factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions. Development. 117:1993;1113-1123.
22. Heitzler P, Bourouis M, Ruel L, Carteret C, Simpson P. Genes of the Enhancer of split and achaete - scute complexes are required for a regulatory loop between Notch and Delta during lateral signalling in Drosophila. Development. 122:1996;161-171 A functional assay is used to show that cells require achaete - scute activity in order to send the inhibitory signal Delta. Together with [24], this suggests that the feedback loop between Notch and Delta involves the achaete - scute genes themselves is under transcriptional control.
23. Haenlin M, Kunisch M, Kramatschek B, Campos-Ortega JA. Genomic regions regulating early embryonic expression of the Drosophila neurogenic gene Delta. Mech Dev. 47:1994;99-110.
24. Kÿnisch M, Haenlin M, Campos-Ortega J. Lateral inhibition mediated by the Drosophila neurogenic gene Delta is enhanced by proneural proteins. Proc Natl Acad Sci USA. 91:1994;10139-10143.
25. Cubas P, de Celis J-F, Campuzano S, Modolell J. Proneural clusters of achaete - scute expression and the generation of sensory organs in the Drosophila imaginal wing disc. Genes Dev. 5:1991;996-1008.
26. Skeath J, Carroll S. Regulation of achaete-scute gene expression and sensory organ pattern formation in the Drosophila wing. Genes Dev. 5:1991;984-995.
27. Parks AL, Muskavitch MAT. Delta function is required for bristle organ determination and morphogenesis in Drosophila. Dev Biol. 157:1993;484-496.
28. Cubas P, Modolell J. The extramacrochaetae gene provides information for sensory organ patterning. EMBO J. 11:1992;3385-3393.
29. Van Doren M, Ellis HM, Posakony JW. The Drosophila extramacrochaetae protein antagonizes sequence-specific DNA binding by daughterless/achaete - scute protein complexes. Development. 113:1991;245-255.
30. Garrell J, Modolell J. The Drosophila extramacrochaetae locus, an antagonist of proneural genes that, like these genes, encodes a helix-loop-helix protein. Cell. 61:1990;39-48.
31. Moscoso del Prado J, Garcia-Bellido A. Cell interactions in the generation of chaetae pattern in Drosophila. Roux's Arch Dev Biol. 193:1984;246-251.
32. Huang F, van Helden J, Dambly-Chaudire C, Ghysen A. Contribution of the gene extramacrochaetae to the precise positioning of bristles in Drosophila. Roux's Arch Dev Biol. 204:1995;336-343.
33. Phillips RG, Whittle R. wingless expression mediates determination of peripheral nervous system elements in late stages of Drosophila wing disc development. Development. 118:1993;427-438.
34. Simpson P, Carteret C. A study of shaggy reveals spatial domains of achaete-scute alleles on the thorax of Drosophila. Development. 106:1989;57-66.
35. Ramain P, Heitzler P, Haenlin M, Simpson P. pannier, a negative regulator of achaete and scute in Drosophila, encodes a zinc finger protein with homology to the vertebrate transcription factor GATA-1. Development. 119:1993;1277-1291.
36. Heitzler P, Haenlin M, Ramain P, Calleja M, Simpson P. A genetic analysis of pannier, a gene necessary for viability of dorsal tissues and bristle positioning in Drosophila. Genetics. 143:1996;1271-1286.
37. Calleja M, Moreno E, Petaz S, Morata G. Visualization of gene expression in living adult Drosophila. of outstanding interest Science. 274:1996;252-255 A novel approach to mutagenesis, based on the mobilization of a modified P-element containing GAL4 that drives expression of UAS-yellow, allows the direct detection in living flies of the spatial expression patterns of genes that are active during the generation of adult structures. A number of lines exhibiting stripe-like expression patterns on the thorax have been found. These suggest the existence of an underlying prepattern based on longitudinal stripes of gene expression.
38. Lehmann R, Jimenez F, Dietrich U, Campos-Ortega J. On the phenotype and development of mutants of early neurogenesis in Drosophila melanogaster. Roux's Arch Dev Biol. 192:1983;62-74.
39. Brand HA, Perrimon N. Targeted gene expression as a means of altering cell fates and generating dominant phenotypes. Development. 118:1993;401-415.
40. Seugnet L, Simpson P, Haenlin M. Transcriptional regulation of Notch and Delta: requirement for neuroblast segregation in Drosophila. of outstanding interest Development. 1997; The GAL4-UAS method [39] is used to obtain uniform Notch or Delta expression in the respective mutant background. Transcriptional regulation of Notch and Delta is dispensable in the embryonic central nervous system of Drosophila.
41. Muskavitch MAT. Delta - Notch signalling and Drosophila cell fate choice. Dev Biol. 166:1994;415-430.
42. Wigglesworth VB. Local and general factors in the development of 'pattern' in Rhodnius prolixus (Hemiptera). J Exp Biol. 17:1940;180-200.
43. Simpson P. Drosophila development: a prepattern for sensory organs. Curr Biol. 6:1996;948-950.
44. Vandervorst P, Ghysen A. Genetic control of sensory connections in Drosophila. Nature. 286:1980;65-67.
45. Seydoux G, Greenwald I. Cell autonomy of lin-12 function in a cell fate decision in C. elegans. Cell. 57:1989;1237-1245.
46. Wilkinson HA, Fitzgerald K, Greenwald I. Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision. Cell. 79:1994;1187-1198.
47. Felix MA, Sternberg PW. Symmetry breakage in the development of one-armed gonads in nematodes. of outstanding interest Development. 122:1996;2129-2142 The authors examine several nematode species and show, that - whereas in C. elegans the anchor cell is chosen stochastically from two equivalent cells by lateral signalling - in other species the outcome may be biased towards one of the two cells although both cells retain competence to make an anchor cell. In yet other species, the choice of anchor cell is predetermined by earlier asymmetries and no other cells are competent to make an anchor cell.