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Volumn 8, Issue 2, 1997, Pages 128-138

Current status of CD4-based therapies for prophylaxis and treatment of HIV infection

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD4 IMMUNOGLOBULIN; SOLUBLE CD4 ANTIGEN;

EID: 0030748472     PISSN: 11738804     EISSN: None     Source Type: Journal    
DOI: 10.2165/00063030-199708020-00006     Document Type: Review
Times cited : (3)

References (61)
  • 1
    • 0023580063 scopus 로고
    • Blocking of HIV-1 infectivity by a soluble secreted form of the CD4 antigen
    • Dec
    • Smith DH, Bryn RA, Marsters SA, et al. Blocking of HIV-1 infectivity by a soluble secreted form of the CD4 antigen. Science 1987 Dec; 238: 1704-7
    • (1987) Science , vol.238 , pp. 1704-1707
    • Smith, D.H.1    Bryn, R.A.2    Marsters, S.A.3
  • 2
    • 0023845937 scopus 로고
    • A soluble form of CD4 (T4) protein inhibits AIDS virus infection
    • Jan
    • Deen KC, McDougal JS, Inacker R, et al. A soluble form of CD4 (T4) protein inhibits AIDS virus infection. Nature 1988 Jan; 331: 82-4
    • (1988) Nature , vol.331 , pp. 82-84
    • Deen, K.C.1    McDougal, J.S.2    Inacker, R.3
  • 3
    • 0023867450 scopus 로고
    • Soluble CD4 molecules neutralise human immunodeficiency virus type 1
    • Jan
    • Trunecker A, Luke W, Karjalainen K. Soluble CD4 molecules neutralise human immunodeficiency virus type 1. Nature 1988 Jan; 331: 84-6
    • (1988) Nature , vol.331 , pp. 84-86
    • Trunecker, A.1    Luke, W.2    Karjalainen, K.3
  • 4
    • 0023833835 scopus 로고
    • HIV infection is blocked in vitro by recombinant soluble CD4
    • Jan
    • Fisher RA, Bertonis JM, Meier W, et al. HIV infection is blocked in vitro by recombinant soluble CD4. Nature 1988 Jan; 331: 76-8
    • (1988) Nature , vol.331 , pp. 76-78
    • Fisher, R.A.1    Bertonis, J.M.2    Meier, W.3
  • 5
    • 0023864652 scopus 로고
    • A soluble CD4 protein selectively inhibits HIV replication and syncytium formation
    • Jan
    • Hussey RE, Richardson NE, Kowalski M, et al. A soluble CD4 protein selectively inhibits HIV replication and syncytium formation. Nature 1988 Jan; 331: 87-91
    • (1988) Nature , vol.331 , pp. 87-91
    • Hussey, R.E.1    Richardson, N.E.2    Kowalski, M.3
  • 6
    • 0025572710 scopus 로고
    • Dissociation of gp120 from HIV-1 virons induced by soluble CD4
    • Nov
    • Moore JP, McKeating JA, Weiss RA, et al. Dissociation of gp120 from HIV-1 virons induced by soluble CD4. Science 1990 Nov; 250: 1139-42
    • (1990) Science , vol.250 , pp. 1139-1142
    • Moore, J.P.1    McKeating, J.A.2    Weiss, R.A.3
  • 7
    • 0030002637 scopus 로고    scopus 로고
    • HIV-1 entry cofactor: Functional cDNA cloning of a seven transmembrane G protein-coupled receptor
    • May
    • Feng Y, Broder CC, Kennedy PE, et al. HIV-1 entry cofactor: functional cDNA cloning of a seven transmembrane G protein-coupled receptor. Science 1996 May; 272: 872-7
    • (1996) Science , vol.272 , pp. 872-877
    • Feng, Y.1    Broder, C.C.2    Kennedy, P.E.3
  • 8
    • 15844419153 scopus 로고    scopus 로고
    • Identification of a major coreceptor for primary isolates of HIV-1
    • Deng H, Liu R, Ellmeir W, et al. Identification of a major coreceptor for primary isolates of HIV-1. Nature 1996; 381: 661-6
    • (1996) Nature , vol.381 , pp. 661-666
    • Deng, H.1    Liu, R.2    Ellmeir, W.3
  • 9
    • 0005014748 scopus 로고    scopus 로고
    • The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
    • Choe H, Farzan M, Sun Y, et al. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell 1996; 85: 1135-48
    • (1996) Cell , vol.85 , pp. 1135-1148
    • Choe, H.1    Farzan, M.2    Sun, Y.3
  • 10
    • 0030018156 scopus 로고    scopus 로고
    • ce CKR5: A RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-trophic HIV-1
    • Alkhatib G, Combadiere C, Broder C, et al. ce CKR5: a RANTES, MIP-1α, MIP-1β receptor as a fusion cofactor for macrophage-trophic HIV-1. Science 1996; 272: 1955-8
    • (1996) Science , vol.272 , pp. 1955-1958
    • Alkhatib, G.1    Combadiere, C.2    Broder, C.3
  • 11
    • 0030604727 scopus 로고    scopus 로고
    • A dual-trophic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors
    • Doranz B, Rucker J, Yi Y, et al. A dual-trophic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors. Cell 1996; 85: 1149-58
    • (1996) Cell , vol.85 , pp. 1149-1158
    • Doranz, B.1    Rucker, J.2    Yi, Y.3
  • 12
    • 15844389650 scopus 로고    scopus 로고
    • HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5
    • Dragic T, Litwin V, Allaway G, et al. HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5. Nature 1996; 381: 667-73
    • (1996) Nature , vol.381 , pp. 667-673
    • Dragic, T.1    Litwin, V.2    Allaway, G.3
  • 13
    • 0026096522 scopus 로고
    • Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virons: Gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralisation by soluble CD4
    • Mar
    • Moore JP, McKeating JA, Norton WA, et al. Direct measurement of soluble CD4 binding to human immunodeficiency virus type 1 virons: gp120 dissociation and its implications for virus-cell binding and fusion reactions and their neutralisation by soluble CD4. J Virol 1991 Mar; 65 (3): 1133-40
    • (1991) J Virol , vol.65 , Issue.3 , pp. 1133-1140
    • Moore, J.P.1    McKeating, J.A.2    Norton, W.A.3
  • 14
    • 0025313226 scopus 로고
    • Relative inefficiency of soluble recombinant CD4 for inhibition of infection by monocyte-trophic HIV in monocytes and T cells
    • Jun
    • Gomatos PJ, Stamatos NM, Gendelman HE, et al. Relative inefficiency of soluble recombinant CD4 for inhibition of infection by monocyte-trophic HIV in monocytes and T cells. J Immunol 1990 Jun; 144 (11): 4183-8
    • (1990) J Immunol , vol.144 , Issue.11 , pp. 4183-4188
    • Gomatos, P.J.1    Stamatos, N.M.2    Gendelman, H.E.3
  • 15
    • 0024561088 scopus 로고
    • Effect of recombinant soluble CD4 in Rhesus monkeys infected with simian immunodeficiency virus of macaques
    • Jan
    • Watanabe M, Reimann KA, DeLong PA, et al. Effect of recombinant soluble CD4 in Rhesus monkeys infected with simian immunodeficiency virus of macaques. Nature 1989 Jan; 337: 267-70
    • (1989) Nature , vol.337 , pp. 267-270
    • Watanabe, M.1    Reimann, K.A.2    DeLong, P.A.3
  • 16
    • 0025139075 scopus 로고
    • The safety and pharmacokinetics of recombinant soluble CD4 (rCD4) in subjects with the acquired immunodeficiency syndrome (AIDS) and AIDS related complex
    • Feb
    • Kahn JO, Allan JD, Hodges TL, et al. The safety and pharmacokinetics of recombinant soluble CD4 (rCD4) in subjects with the acquired immunodeficiency syndrome (AIDS) and AIDS related complex. Ann Intern Med 1990 Feb; 112 (4): 254-61
    • (1990) Ann Intern Med , vol.112 , Issue.4 , pp. 254-261
    • Kahn, J.O.1    Allan, J.D.2    Hodges, T.L.3
  • 17
    • 0025093595 scopus 로고
    • Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex
    • Feb
    • Schooley RT, Merigan TC, Gaut P, et al. Recombinant soluble CD4 therapy in patients with the acquired immunodeficiency syndrome (AIDS) and AIDS-related complex. Ann Intern Med 1990 Feb; 112 (4): 247-53
    • (1990) Ann Intern Med , vol.112 , Issue.4 , pp. 247-253
    • Schooley, R.T.1    Merigan, T.C.2    Gaut, P.3
  • 18
    • 0025016076 scopus 로고
    • High concentrations of recombinant soluble CD4 are required to neutralise primary human immunodeficiency virus type 1 isolates
    • Sept
    • Daar ES, Li XL, Moudgil T, et al. High concentrations of recombinant soluble CD4 are required to neutralise primary human immunodeficiency virus type 1 isolates. Proc Natl Acad Sci USA 1990 Sept; 87: 6574-8
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 6574-6578
    • Daar, E.S.1    Li, X.L.2    Moudgil, T.3
  • 19
    • 0025886458 scopus 로고
    • Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity
    • Aug
    • Ashkenazi A, Smith DH, Marsters SA, et al. Resistance of primary isolates of human immunodeficiency virus type 1 to soluble CD4 is independent of CD4-rgp120 binding affinity. Proc Natl Acad Sci USA 1991 Aug; 88: 7056-60
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7056-7060
    • Ashkenazi, A.1    Smith, D.H.2    Marsters, S.A.3
  • 20
    • 0025807938 scopus 로고
    • Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralisation by soluble CD4 possess high affinity for the CD4 receptor
    • Sep
    • Brighty DW, Rosenburg M, Chen ISY, et al. Envelope proteins from clinical isolates of human immunodeficiency virus type 1 that are refractory to neutralisation by soluble CD4 possess high affinity for the CD4 receptor. Proc Natl Acad Sci USA 1991 Sep; 88: 7802-5
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 7802-7805
    • Brighty, D.W.1    Rosenburg, M.2    Chen, I.S.Y.3
  • 21
    • 0026601827 scopus 로고
    • Virons of human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralisation differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates
    • Jan
    • Moore JP, McKeating JA, Huang Y, et al. Virons of human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralisation differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates. J Virol 1992 Jan; 66 (1): 235-43
    • (1992) J Virol , vol.66 , Issue.1 , pp. 235-243
    • Moore, J.P.1    McKeating, J.A.2    Huang, Y.3
  • 22
    • 0026587543 scopus 로고
    • Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles
    • Sato H, Orenstein J, Dimitrov D, et al. Cell-to-cell spread of HIV-1 occurs within minutes and may not involve the participation of virus particles. Virology 1992; 186: 721-4
    • (1992) Virology , vol.186 , pp. 721-724
    • Sato, H.1    Orenstein, J.2    Dimitrov, D.3
  • 23
    • 0024506156 scopus 로고
    • Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibody
    • May
    • Gupta P, Balachandran R, Ho M, et al. Cell-to-cell transmission of human immunodeficiency virus type 1 in the presence of azidothymidine and neutralizing antibody. J Virol 1989 May; 63 (5): 2361-5
    • (1989) J Virol , vol.63 , Issue.5 , pp. 2361-2365
    • Gupta, P.1    Balachandran, R.2    Ho, M.3
  • 24
    • 0028233744 scopus 로고
    • The role of cell-to-cell transmission in HIV infection
    • Phillips DM. The role of cell-to-cell transmission in HIV infection. AIDS 1994; 8: 719-31
    • (1994) AIDS , vol.8 , pp. 719-731
    • Phillips, D.M.1
  • 25
    • 0027538456 scopus 로고
    • HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease
    • Mar
    • Pantaleo G, Graziosi C, Demarest JF, et al. HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease. Nature 1993 Mar; 362: 355-8
    • (1993) Nature , vol.362 , pp. 355-358
    • Pantaleo, G.1    Graziosi, C.2    Demarest, J.F.3
  • 26
    • 0027976755 scopus 로고
    • The effects of high dose recombinant soluble CD4 on human immunodeficiency virus type 1 viraemia
    • Jan
    • Schacker T, Coombs RW, Collier AC, et al. The effects of high dose recombinant soluble CD4 on human immunodeficiency virus type 1 viraemia. J Infect Dis 1994 Jan; 169: 37-40
    • (1994) J Infect Dis , vol.169 , pp. 37-40
    • Schacker, T.1    Coombs, R.W.2    Collier, A.C.3
  • 27
    • 0024575860 scopus 로고
    • Designing CD4 immunoadhesins for AIDS therapy
    • Feb
    • Capon DJ, Chamow SM, Mordenti J, et al. Designing CD4 immunoadhesins for AIDS therapy. Nature 1989 Feb; 337: 525-31
    • (1989) Nature , vol.337 , pp. 525-531
    • Capon, D.J.1    Chamow, S.M.2    Mordenti, J.3
  • 28
    • 0024549563 scopus 로고
    • Highly efficient neutralisation of HIV with recombinant CD4-immunoglobulin molecules
    • May
    • Traunecker A, Schneider J, Kiefer H, et al. Highly efficient neutralisation of HIV with recombinant CD4-immunoglobulin molecules. Nature 1989 May; 339: 68-70
    • (1989) Nature , vol.339 , pp. 68-70
    • Traunecker, A.1    Schneider, J.2    Kiefer, H.3
  • 29
    • 0025269979 scopus 로고
    • Biological properties of a CD4 immunoadhesin
    • Apr
    • Byrn RA, Mordenti J, Lucas C, et al. Biological properties of a CD4 immunoadhesin. Nature 1990 Apr; 344: 667-70
    • (1990) Nature , vol.344 , pp. 667-670
    • Byrn, R.A.1    Mordenti, J.2    Lucas, C.3
  • 30
    • 0028079045 scopus 로고
    • HIV-1 strain dependence of complement-mediated virolysis induced by recombinant CD4-IgG
    • Spear GT, Ghassemi M, Takefman DM. HIV-1 strain dependence of complement-mediated virolysis induced by recombinant CD4-IgG [letter]. J Acquir Immune Defic Syndr 1994; 7: 100-1
    • (1994) J Acquir Immune Defic Syndr , vol.7 , pp. 100-101
    • Spear, G.T.1    Ghassemi, M.2    Takefman, D.M.3
  • 31
    • 0029062687 scopus 로고
    • Expression and characterisation of CD4-IgG2, a novel heteroletramer that neutralises primary HIV type 1 isolates
    • Allaway GP, Davis-Bruno KL, Beaudry GA, et al. Expression and characterisation of CD4-IgG2, a novel heteroletramer that neutralises primary HIV type 1 isolates. AIDS Res Hum Retrovir 1995; 11: 533-9
    • (1995) AIDS Res Hum Retrovir , vol.11 , pp. 533-539
    • Allaway, G.P.1    Davis-Bruno, K.L.2    Beaudry, G.A.3
  • 32
    • 0029875107 scopus 로고    scopus 로고
    • Effective ex vivo neutralisation of plasma HIV-1 by recombinant immunoglobulin molecules
    • Gauduin M, Allaway GP, Maddon PJ, et al. Effective ex vivo neutralisation of plasma HIV-1 by recombinant immunoglobulin molecules. J Virol 1996; 70: 2586-92
    • (1996) J Virol , vol.70 , pp. 2586-2592
    • Gauduin, M.1    Allaway, G.P.2    Maddon, P.J.3
  • 33
    • 85036493441 scopus 로고
    • A phase I trial of recombinant human CD4-immunoglobulin(rCD4-IgG) in HIV-1 infection [abstract no. SB481]
    • Jun; San Francisco
    • Davey R, Davey V, Polis M, et al. A phase I trial of recombinant human CD4-immunoglobulin(rCD4-IgG) in HIV-1 infection [abstract no. SB481]. Proc VIth International Conference on AIDS; 1990 Jun; San Francisco: 206
    • (1990) Proc VIth International Conference on AIDS , pp. 206
    • Davey, R.1    Davey, V.2    Polis, M.3
  • 34
    • 0026037210 scopus 로고
    • Phase 1 study of recombinant human CD4-immunoglobulin G therapy of patients with AIDS and AIDS-related complex
    • Dec
    • Hodges TL, Kahn JO, Kaplan LD, et al. Phase 1 study of recombinant human CD4-immunoglobulin G therapy of patients with AIDS and AIDS-related complex. Antimicrob Agents Chemother 1991 Dec; 35 (12): 2580-6
    • (1991) Antimicrob Agents Chemother , vol.35 , Issue.12 , pp. 2580-2586
    • Hodges, T.L.1    Kahn, J.O.2    Kaplan, L.D.3
  • 35
    • 0029096184 scopus 로고
    • Safety, pharmacokinetics, and antiviral response of CD4-immunoglobulin G by intravenous bolus in AIDS and AIDS-related complex
    • Collier AC, Coombs RW, Katzenstein D, et al. Safety, pharmacokinetics, and antiviral response of CD4-immunoglobulin G by intravenous bolus in AIDS and AIDS-related complex. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 10 (2): 150-6
    • (1995) J Acquir Immune Defic Syndr Hum Retrovirol , vol.10 , Issue.2 , pp. 150-156
    • Collier, A.C.1    Coombs, R.W.2    Katzenstein, D.3
  • 36
    • 85004781885 scopus 로고
    • Phase 1 study of rCD4-IgG administered by continuous intravenous (IV) infusion to patients with AIDS or ARC [abstract no. SB479]
    • June; San Francisco
    • Yarchoan Y, Plauda JM, Adamo D, et al. Phase 1 study of rCD4-IgG administered by continuous intravenous (IV) infusion to patients with AIDS or ARC [abstract no. SB479]. Proc VIth International Conference on AIDS; 1990 June; San Francisco: 205
    • (1990) Proc VIth International Conference on AIDS , pp. 205
    • Yarchoan, Y.1    Plauda, J.M.2    Adamo, D.3
  • 38
    • 0027291349 scopus 로고
    • Effect of a recombinant CD4-IgG on in vitro T helper cell function: Data from a phase I/II study of patients with AIDS
    • Oct
    • Clerici M, Yarchoan R, Blatt S, et al. Effect of a recombinant CD4-IgG on in vitro T helper cell function: data from a phase I/II study of patients with AIDS. J Infect Dis 1993 Oct; 168: 1012-6
    • (1993) J Infect Dis , vol.168 , pp. 1012-1016
    • Clerici, M.1    Yarchoan, R.2    Blatt, S.3
  • 39
    • 0025810157 scopus 로고
    • Helper T cell responses in children infected with human immunodeficiency virus type I
    • Roilides E, Clerici M, DePalma L, et al. Helper T cell responses in children infected with human immunodeficiency virus type I. J Pediatr 1991; 118: 724-30
    • (1991) J Pediatr , vol.118 , pp. 724-730
    • Roilides, E.1    Clerici, M.2    DePalma, L.3
  • 40
    • 0025991477 scopus 로고
    • Human immunodeficiency virus infection in the US Air Force: Seroconversions, clinical staging, and assessment of T helper functional assay to predict change in CD4+ T cell counts
    • Lucey DR, Melcher GP, Hendrix CW, et al. Human immunodeficiency virus infection in the US Air Force: seroconversions, clinical staging, and assessment of T helper functional assay to predict change in CD4+ T cell counts. J Infect Dis 1991; 164: 631-7
    • (1991) J Infect Dis , vol.164 , pp. 631-637
    • Lucey, D.R.1    Melcher, G.P.2    Hendrix, C.W.3
  • 41
    • 0027153281 scopus 로고
    • CDC Cooperative Needlestick Surveillance Group: Surveillance of HIV infection and zidovudine use among health care workers after occupational exposure to HIV-infected blood
    • Tokars JI, Marcus R, Culver DH, et al. CDC Cooperative Needlestick Surveillance Group: surveillance of HIV infection and zidovudine use among health care workers after occupational exposure to HIV-infected blood. Ann Intern Med 1993; 118: 913-9
    • (1993) Ann Intern Med , vol.118 , pp. 913-919
    • Tokars, J.I.1    Marcus, R.2    Culver, D.H.3
  • 42
    • 8544241526 scopus 로고
    • Managing occupational exposures to HIV
    • Broder S, Merigan TC, Bolognesi D, editors. Baltimore: Williams & Wilkins
    • Gerberding JL. Managing occupational exposures to HIV. In: Broder S, Merigan TC, Bolognesi D, editors. Textbook of AIDS medicine. Baltimore: Williams & Wilkins, 1994: 841-3
    • (1994) Textbook of AIDS Medicine , pp. 841-843
    • Gerberding, J.L.1
  • 43
    • 0028003766 scopus 로고
    • Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment
    • Nov
    • Connor EM, Sperling RS, Gelber R, et al. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment. N Engl J Med 1994 Nov; 331 (18): 1173-80
    • (1994) N Engl J Med , vol.331 , Issue.18 , pp. 1173-1180
    • Connor, E.M.1    Sperling, R.S.2    Gelber, R.3
  • 44
    • 0025900885 scopus 로고
    • Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesion
    • Aug
    • Ward RHR, Capon DJ, Jett CM, et al. Prevention of HIV-1 IIIB infection in chimpanzees by CD4 immunoadhesion. Nature 1991 Aug; 352: 434-6
    • (1991) Nature , vol.352 , pp. 434-436
    • Ward, R.H.R.1    Capon, D.J.2    Jett, C.M.3
  • 45
    • 0029044145 scopus 로고
    • Transport of recombinant CD4-immunoglobulin G across the human placenta: Pharmacokinetics and safety in six mother-infant pairs in AIDS Clinical Trial Group Protocol 146
    • May
    • Shearer WT, Duliege AM, Kline MK, et al. Transport of recombinant CD4-immunoglobulin G across the human placenta: pharmacokinetics and safety in six mother-infant pairs in AIDS Clinical Trial Group Protocol 146. Clin Lab Diag Immunol 1995 May; 2 (3): 281-5
    • (1995) Clin Lab Diag Immunol , vol.2 , Issue.3 , pp. 281-285
    • Shearer, W.T.1    Duliege, A.M.2    Kline, M.K.3
  • 46
    • 0024566560 scopus 로고
    • Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by recombinant soluble CD4 and 3′-azido-3′-deoxythymidine
    • May
    • Johnson VA, Barlow BD, Chou T, et al. Synergistic inhibition of human immunodeficiency virus type 1 replication in vitro by recombinant soluble CD4 and 3′-azido-3′-deoxythymidine. J Infect Dis 1989 May; 159 (5): 837-44
    • (1989) J Infect Dis , vol.159 , Issue.5 , pp. 837-844
    • Johnson, V.A.1    Barlow, B.D.2    Chou, T.3
  • 47
    • 0025284777 scopus 로고
    • Three drug synergistic inhibition of HIV-1 replication in vitro by zidovudine, recombinant soluble CD4, and recombinant interferon-alpha a
    • June
    • Johnson VA, Barlow BD, Merrill DP, et al. Three drug synergistic inhibition of HIV-1 replication in vitro by zidovudine, recombinant soluble CD4, and recombinant interferon-alpha A. J Infect Dis 1990 June; 161: 1059-67
    • (1990) J Infect Dis , vol.161 , pp. 1059-1067
    • Johnson, V.A.1    Barlow, B.D.2    Merrill, D.P.3
  • 48
    • 0027214287 scopus 로고
    • Nevaripine synergistically inhibits HIV-1 replication in combination with zidovudine, interferon or CD4 immunoadhesion
    • Koup RA, Brewster F, Grob P. Nevaripine synergistically inhibits HIV-1 replication in combination with zidovudine, interferon or CD4 immunoadhesion. AIDS 1993; 7 (9): 1181-4
    • (1993) AIDS , vol.7 , Issue.9 , pp. 1181-1184
    • Koup, R.A.1    Brewster, F.2    Grob, P.3
  • 49
    • 0028200431 scopus 로고
    • Synergistic effect of recombinant CD4-immunoglobulin in combination with azidothymidine, dideoxyinosine, and 0.5β monoclonal antibody on human immunodeficiency virus infection in vitro
    • Ushijima H, Kunisada T, Kitamura T, et al. Synergistic effect of recombinant CD4-immunoglobulin in combination with azidothymidine, dideoxyinosine, and 0.5β monoclonal antibody on human immunodeficiency virus infection in vitro. Lett Appl Microbiol 1994; 19: 1-5
    • (1994) Lett Appl Microbiol , vol.19 , pp. 1-5
    • Ushijima, H.1    Kunisada, T.2    Kitamura, T.3
  • 50
    • 0028966285 scopus 로고
    • Combination therapy with recombinant human soluble CD4-immunoglobulin G and zidovudine in patients with HIV infection: A phase I study
    • Meng TC, Fischl MA, Cheeseman SH, et al. Combination therapy with recombinant human soluble CD4-immunoglobulin G and zidovudine in patients with HIV infection: a phase I study. J Acquir Immune Defic Syndr Hum Retrovirol 1995; 8 (2): 152-60
    • (1995) J Acquir Immune Defic Syndr Hum Retrovirol , vol.8 , Issue.2 , pp. 152-160
    • Meng, T.C.1    Fischl, M.A.2    Cheeseman, S.H.3
  • 51
    • 0026349231 scopus 로고
    • Analysis of synergism/antagonism between HIV-1 antibody positive human sera and soluble CD4 in blocking HIV-1 binding and infectivity
    • Kennedy MS, Orloff S, Ibegbu CC, et al. Analysis of synergism/antagonism between HIV-1 antibody positive human sera and soluble CD4 in blocking HIV-1 binding and infectivity. AIDS Res Hum Retrovir 1991; 7 (12): 975-81
    • (1991) AIDS Res Hum Retrovir , vol.7 , Issue.12 , pp. 975-981
    • Kennedy, M.S.1    Orloff, S.2    Ibegbu, C.C.3
  • 52
    • 0027055318 scopus 로고
    • Synergistic interaction between ligands binding to the CD4 binding site and V3 domain of human immunodeficiency virus type 1 gp 120
    • McKeating J A, Cordell J, Dean CJ, et al. Synergistic interaction between ligands binding to the CD4 binding site and V3 domain of human immunodeficiency virus type 1 gp 120. Virology 1992; 191: 732-42
    • (1992) Virology , vol.191 , pp. 732-742
    • McKeating, J.A.1    Cordell, J.2    Dean, C.J.3
  • 53
    • 0027257744 scopus 로고
    • Synergistic inhibition of HIV-1 envelope mediated cell fusion by CD4 based molecules in combination with antibodies to gp120 or gp41
    • Allaway GP, Ryder AM, Beaudry GA, et al. Synergistic inhibition of HIV-1 envelope mediated cell fusion by CD4 based molecules in combination with antibodies to gp120 or gp41. AIDS Res Hum Retrovir 1993; 9 (7): 581-7
    • (1993) AIDS Res Hum Retrovir , vol.9 , Issue.7 , pp. 581-587
    • Allaway, G.P.1    Ryder, A.M.2    Beaudry, G.A.3
  • 54
    • 0023784225 scopus 로고
    • Selective killing of HIV-1 infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein
    • Sept
    • Chaudhary VK, Mizukami T, Fuerst TR, et al. Selective killing of HIV-1 infected cells by recombinant human CD4-Pseudomonas exotoxin hybrid protein. Nature 1988 Sept; 335: 369-72
    • (1988) Nature , vol.335 , pp. 369-372
    • Chaudhary, V.K.1    Mizukami, T.2    Fuerst, T.R.3
  • 55
    • 0024398753 scopus 로고
    • CD4-Pseudomonas exotoxin hybrid protein blocks the spread of human immunodeficiency virus in vitro and is active against cells expressing the envelope glycoproteins from diverse primate immunodeficiency retroviruses
    • Dec
    • Berger EA, Clouse KA, Chaudhary VK, et al. CD4-Pseudomonas exotoxin hybrid protein blocks the spread of human immunodeficiency virus in vitro and is active against cells expressing the envelope glycoproteins from diverse primate immunodeficiency retroviruses. Proc Natl Acad Sci USA 1989 Dec; 86: 9539-43
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9539-9543
    • Berger, E.A.1    Clouse, K.A.2    Chaudhary, V.K.3
  • 56
    • 0025225451 scopus 로고
    • Elimination of infectious human immunodeficiency virus from human T-cell culture by synergistic action of CD4-Psseudomonas exotoxin and reverse transcriptase inhibitors
    • Nov
    • Ashorn P, Moss B, Weinstein JN, et al. Elimination of infectious human immunodeficiency virus from human T-cell culture by synergistic action of CD4-Psseudomonas exotoxin and reverse transcriptase inhibitors. Proc Natl Acad Sci USA 1990 Nov; 87: 8889-93
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8889-8893
    • Ashorn, P.1    Moss, B.2    Weinstein, J.N.3
  • 57
    • 0025165343 scopus 로고
    • Recombinant CD4-Pseudomonas exotoxin hybrid protein displays HIV-specific cytotoxicity without affecting MHC class II dependent functions
    • Berger EA, Chaudhary VK, Clouse KA, et al. Recombinant CD4-Pseudomonas exotoxin hybrid protein displays HIV-specific cytotoxicity without affecting MHC class II dependent functions. AIDS Res Hum Retrovir 1990; 6 (6): 795-804
    • (1990) AIDS Res Hum Retrovir , vol.6 , Issue.6 , pp. 795-804
    • Berger, E.A.1    Chaudhary, V.K.2    Clouse, K.A.3
  • 58
    • 0027965596 scopus 로고
    • Failure of short term CD4-PE40 infusion to reduce virus load in human immunodeficiency virus infected persons
    • Oct
    • Ramachandran R, Katzenstein DA, Wood R, et al. Failure of short term CD4-PE40 infusion to reduce virus load in human immunodeficiency virus infected persons. J Infect Dis 1994 Oct; 170: 1009-13
    • (1994) J Infect Dis , vol.170 , pp. 1009-1013
    • Ramachandran, R.1    Katzenstein, D.A.2    Wood, R.3
  • 59
    • 0027937671 scopus 로고
    • Liposome targeting to human immunodeficiency virus type 1 infected cells via recombinant soluble CD4 and CD4 immunoadhesin (CD4-IgG)
    • Flasher D, Konopka K, Chamow SM, et al. Liposome targeting to human immunodeficiency virus type 1 infected cells via recombinant soluble CD4 and CD4 immunoadhesin (CD4-IgG). Biochim Biophys Acta 1994; 1194: 185-96
    • (1994) Biochim Biophys Acta , vol.1194 , pp. 185-196
    • Flasher, D.1    Konopka, K.2    Chamow, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.