Structure and function of the xenobiotic substrate-binding site and location of a potential non-substrate-binding site in a class π glutathione S-transferase

Biochemistry

Volumn 36, Issue 32, 1997, Pages 9690-9702

  Ji, Xinhua ^a   Tordova, Maria ^b   O'Donnell, Rosemary ^a   Parsons, James F ^c   Hayden, Janet B ^d   Gilliland, Gary L ^b   Zimniak, Piotr ^d  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d CENTRAL ARKANSAS VETERANS HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTATHIONE TRANSFERASE;

ARTICLE; BINDING SITE; CRYSTALLOGRAPHY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; HYDROPHILICITY; HYDROPHOBICITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; XENOBIOTIC METABOLISM;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CRYSTALLOGRAPHY, X-RAY; ELECTROSTATICS; GLUTATHIONE TRANSFERASE; HEPES; HUMANS; MICE; RATS; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP; SUBSTRATE SPECIFICITY; WATER; XENOBIOTICS;

EID: 0030748102     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi970805s     Document Type: Article

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