Structural studies of a human pi class glutathione S-transferase

Biochemical Pharmacology

Volumn 52, Issue 2, 1996, Pages 281-288

  Whalen, Richard ^a   Kempner, Ellis S ^b   Boyer, Thomas D ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

active site; affinity labels; glutathione transferases; human; protein structure; radiation effects

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; COMPLEMENTARY DNA; GLUTATHIONE; GLUTATHIONE DERIVATIVE; GLUTATHIONE TRANSFERASE; ISOENZYME;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME KINETICS; ENZYME STRUCTURE; ENZYME SUBUNIT; ESCHERICHIA COLI; GENE EXPRESSION; HUMAN; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; PEPTIDE SYNTHESIS; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; RADIATION;

EID: 0030602878     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(96)00205-5     Document Type: Article

References (37)

1. 1. Boyer TD, The glutathione S-transferases: An update. Hepatology 9: 486-496, 1989.
2. 2. Pickett CB and Lu AYH, Glutathione S-transferases: Gene structure, regulation, and biological function. Annu Rev Biochem 58: 734-764, 1989.
3. 3. Coles B and Ketterer B, The role of glutathione and glutathione transferases in chemical carcinogenesis. CRC Crit Rev Biochem 25: 47-70, 1990.
4. 4. Mannervik B and Danielson UH, Glutathione transferases: Structure and catalytic activity. CRC Crit Rev Biochem 23: 283-337, 1988.
5. 5. Mannervik B, Awasthi YC, Board PG, Hayes JD, Di Ilio C, Ketterer B, Listowsky I, Morgenstern R, Muramatsu M, Pearson WR, Pickett CB, Sato K, Wildersten M and Wolf CR, Nomenclature for human glutathione transferases. Biochem J 282: 305-308, 1992.
6. 6. Boyer TD and Kempner ES, Effect of subunit interactions on enzymatic activity of glutathione S-transferases: A radiation inactivation study. Anal Biochem 207: 51-57, 1992.
7. 7. Jakobson I, Warholm M and Mannervik B, The binding of substrates and a product of the enzymatic reaction to glutathione S-transferase A. J Biol Chem 254: 7085-7089, 1979.
8. 8. Dirr H, Reinemer P and Huber R, X-ray crystal structures of cytosolic glutathione S-transferases. Implications or protein architecture, substrate recognition and catalytic function. Eur J Biochem 220: 645-661, 1994.
9. 9. Reinemer P, Dirr HW, Ladenstein R, Huber R, Lo Bello M, Federici G and Parker MW, Three-dimensional structure of class π glutathione S-transferase from human placenta in complex with S-hexlglutathione at 2.8 Å resolution. J Mol Biol 227: 214-226, 1992.
10. 10. Hoesch RM and Boyer TD, Localization of a portion of the active site of two rat liver glutathione S-transferases using a photoaffinity label. J Biol Chem 264: 17712-17717, 1989.
11. 111 of glutathione S-transferase, isoenzyme 1-1, by S-(4-bromo-2,3-dioxobutyl)glutathione. Biochemistry 31: 8984-8990, 1992.
12. 12. Cooke RJ, Bjornestedt R, Douglas KT, McKie JH, King MD, Coles B, Ketterer B and Mannervik B, Photoaffinity labelling of the active site of the rat glutathione transferases 3-3 and 1-1 and human glutathione transferase A1-1. Biochem J 302: 383-390, 1994.
13. 13. Katusz RM and Colman RF, S-(4-Bromo-2,3,-dioxobutyl)-glutathione: A new affinity label for the 4-4 isozyme of the rat liver glutathione S-transferase. Biochemistry 30: 11230-11238, 1991.
14. 115 labeled by S-(4-bromo-2,3-dioxobutyl)glutathione in the hydrophobic substrate binding site of glutathione S-transferase, isoenzyme 3-3. Arch Biochem Biophys 298: 667-677, 1992.
15. 15. Sato K, Satoh H, Tsuchida S, Hatayama I, Shen H, Yokoyama Y, Yamada Y and Tamai K, Specific expression of glutathione S-transferase pi forms in (pre)neoplastic tissues: Their properties and functions. Tohoku J Exp Med 168: 97-103, 1992.
16. 16. Konohana A, Konohana I, Schroeder WT, O'Brien WR, Amagai M, Greer J, Shimizu N, Gammon WR, Siciliano MJ and Duvic M, Placental glutathione-S-transferase-pi mRNA is abundantly expressed in human skin. J Invest Dermatol 95: 119-126, 1990.
17. 17. Kano T, Sakai M and Muramatsu M, Structure and expression of a human class pi glutathione S-transferase messenger RNA. Cancer Res 47: 5626-5630, 1987.
18. 18. Armaud CD, Tsao HS, and Littledike T, Radioimmunoassay of human parathyroid hormone in serum. J Clin Invest 50: 21-34, 1971.
19. 19. Simons PC and Vander Jagt DL, Purification of glutathione S-transferases from human liver by glutathione-affinity chromatography. Anal Biochem 82: 334-341, 1977.
20. 20. Habig WH, Pabst MJ and Jakoby WB, Glutathione S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 249: 7130-7139, 1974.
21. 21. Hoesch RM and Boyer TD, Purification and characterization of hepatic glutathione S-transferases of rhesus monkeys. Biochem J 251: 81-88, 1988.
22. 22. Laemmli UK, Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.
23. 23. Morrissey JH, Silver stain for proteins in polyacrylamide gels: A modified procedure with enhanced sensitivity. Anal Biochem 117: 307-310, 1981.
24. 24. Towbin H, Staehelin T and Gordon J, Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications. Proc Nad Acad Sci USA 76: 4350-4354, 1979.
25. 25. Matsudaira P, Sequence from picomole quantities of proteins electroblotted onto polyvinylidene diflouride membranes. J Biol Chem 262: 10035-10038, 1987.
26. 26. Coull JM and Pappin DJC, A rapid flourescent staining procedure for proteins electroblotted onto PVDF membranes. J Protein Chem 9: 259-260, 1990.
27. 27. Harmon JT, Nielsen TB and Kempner ES, Molecular weight determinations from radiation inactivation. Methods Enzymol 117: 65-94, 1985.
28. 28. Kendall RL, Yamada R and Bradshaw RA, Cotranslational amino-terminal processing. Methods Enzymol 185: 398-407, 1990.
29. 29. Wang RW, Pickett CB and Lu AYH, Expression of a cDNA encoding a rat liver glutathione S-transferase Ya subunit in Escherichia coli. Arch Biochem Biophys 269: 536-543, 1989.
30. 30. Sinning I, Kleywegt GJ, Cowan SW, Reinemer P, Dirr HW, Huber R, Gilliland GL, Armstrong RN, Ji X, Board PG, Olin B, Mannervik B and Jones TA, Structure determination and refinement of human alpha class glutathione transferase. A1-1, and a comparison with the mu and pi class enzymes. J Mol Biol 232: 192-212, 1993.
31. 31. Ji X, Zhang P, Armstrong RN and Gilliland GL, The three-dimensional structure of a glutathione S-transferase from the mu gene class. Structural analysis of the binary complex of isoenzyme 3-3 and glutathione at 2.2-Å resolution. Biochemistry 31: 10169-10184, 1992.
32. 32. Raghunathan S, Chandross RJ, Kretsinger RH, Allison TJ, Penington CJ and Rule GS, Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity. J Mol Biol 238: 815-832, 1994.
33. 33. Penington CJ and Rule GS, Mapping the substrate-binding site of a human class mu glutathione transferase using nuclear magnetic resonance spectroscopy. Biochemistry 31: 2912-2920, 1992.
34. 34. Board PG and Mannervik B, The contribution of the C-terminal sequence to the catalytic activity of GST2, a human alpha-class glutathione transferase. Biochem J 275: 171-174, 1991.
35. 35. Reinemer P, Dirr HW, Ladenstein R, Schäffer J, Gallay O and Huber R, The three-dimensional structure of class π glutathione S-transferase in complex with glutathione sulfonate at 2.3 Å resolution. EMBO J 10: 1997-2005, 1991.
36. 36. Manoharan TH, Gulick AM, Puchalski RB, Servais AL and Fahl WE, Structural studies on human glutathione S-transferase π. Substitution mutations to determine amino acids necessary for binding glutathione. J Biol Chem 267: 18940-18945, 1992.
37. 37. Potier M, Thauvette L, Michaud L, Giroux S and Beauregard G, Inactivation mechanism of tetrameric β-galactosidase by γ-rays involves both fragmentation and temperature-dependent denaturation of protomers. Biochemistry 30: 8151-8157, 1991.