Mechanistic analyses of site-specific degradation in DNA-RNA hybrids by prototypic DNA cleavers

Nucleic Acids Research

Volumn 25, Issue 9, 1997, Pages 1836-1845

  Bansal, Meena ^a,d   Lee, Jae S ^a,e   Stubbe, Joanne ^b   Kozarich, John W ^a,c  

^a Bldg 142   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MERCK RESEARCH LABORATORIES   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

^e PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; DNA; DOUBLE STRANDED DNA; ESPERAMICIN A1; ESPERAMICIN C; OXYGEN; PYRIMIDINE; RNA; ZINOSTATIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA CLEAVAGE; DNA CONFORMATION; DNA DAMAGE; DNA DEGRADATION; DNA FLANKING REGION; DNA PROBE; DNA RNA HYBRIDIZATION; DNA SEQUENCE; DRUG MECHANISM; METHODOLOGY; NONHUMAN; PRIORITY JOURNAL; RNA CONFORMATION; RNA SEQUENCE;

AMINOGLYCOSIDES; ANTI-BACTERIAL AGENTS; BLEOMYCIN; DNA; ENEDIYNES; HYDROLYSIS; KINETICS; OXYGEN; RNA; ZINOSTATIN;

GALIUM APARINE;

EID: 0030738447     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/25.9.1836     Document Type: Article

References (48)

1. Umezawa, H., Maeda, K., Takeuchi, T. and Okami, Y. (1966) J. Antibiot. Ser. A, 19, 200.
2. Sausville, E.A., Peisach, J. and Horwitz, S.B. (1976) Biochem. Biophys. Res. Commun., 73, 814.
3. Sausville, E.A., Stein, R.W., Peisach, J. and Horwitz, S.B. (1978) Biochemisrry, 17, 2746.
4. Burger, R.M., Peisach, J. and Horwitz, S.B. (1981) J. Biol. Chem., 256, 11636.
5. Sam, J.W., Tang, X.-J. and Peisach, J. (1994) J. Am. Chem. Soc., 116, 5250-5256.
6. Wu, J.C. Kozarich, J.W. and Stubbe, J. (1983) J. Biol. Chem., 258, 4694.
7. Wu, J.C., Kozarich, J.W. and Stubbe, J. (1985) Biochemistry, 24, 7562.
8. Wu, J.C., Stubbe, J. and Kozarich, J.W. (1985) Biochemistry, 24, 7569.
9. Rabow, L.E., Stubbe, J., Kozarich, J.W. and Gerlt, J.A. (1986) J. Am. Chem. Soc., 108, 130.
10. Ajmera, S., Massof, S. and Kozarich, J.W. (1986) J. Labelled Compd Radiopharm., 23, 963.
11. Ajmera, S., Wu, J.C., Stubbe, J., Worth, L., Jr, Stubbe, J. and Kozarich, J.W. (1986) Biochemistry, 25, 6586.
12. Worth, L., Jr. Frank, B.L., Chrismer, D.F., Absalon, M.J., Stubbe, J. and Kozarich, J.W. (1993) Biochemistry, 32, 2601.
13. Golik, J., Clardy, J., Dubay, G., Groenewald, G., Kawaguchi, H., Konishi, M., Krishnan, B., Onkuma, H., Saitoh, K.-I. and Doyle, T.W. (1987) J. Am. Chem. Soc., 109, 3461.
14. Kozarich, J.W., Worth, L., Jr. Frank, B.L., Christner, D.F., Vanderwall, D.E. and Stubbe, J. (1989) Science, 245, 1396.
15. Long, B.H., Golik, J., Forenza, S., Ward, B., Rehfuss, R., Dabrowiak, J.C., Catino, J.J., Musial, S.T., Brookshire, K.W. and Doyle, T.W. (1989) Proc. Natl. Acad. Sci. USA, 86, 2.
16. Christner, D.F., Frank, L.F., Kozarich, J.W., Stubbe, J., Golik, J., Doyle, T.W., Rosenberg, I.E. and Krishnan, B. (1992) J. Am. Chem. Soc., 114, 8763.
17. Yu, L., Goldberg, I.H. and Dedon, P.C. (1994) J. Biol. Chem., 269, 4144-4151.
18. Goldberg, I.H. and Kappen, L.S. (1994) In Borders, D.B. and Doyle, T.W. (eds), Enediyne Antibiotics as Antitumor Agents. p. 327.
19. Myers, A.G., Proteau, P.J. and Jandel, T.M. (1988) J. Am. Chem. Soc., 110, 7212.
20. Kappen, L.S., Goldberg, I.H. and Liesch, J.M. (1982) Proc. Natl. Acad. Sci. USA, 79, 744.
21. Kappen, L.S. and Goldberg, I.H. (1983) Biochemistry, 22, 4872.
22. Frank, B.L., Worth, L., Jr, Christner, D.F., Kozarich, J.W., Stubbe, J. and Goldberg, I.H. (1991) J. Am. Chem. Soc., 113, 2271.
23. Kappen, L.S., Goldberg, I.H., Frank, B.L., Worth, L., Jr. Christner, D.F., Kozarich, J.W. and Stubbe, J. (1991) Biochemistry, 30, 2034.
24. Haidle, C.W. and Bearden, J., Jr (1975) Biochem. Biophys. Res. Commun., 65, 815.
25. Krishnamoorthy, C.R., Vanderwall, D.E., Kozarich, J.W. and Stubbe, J. (1988) J. Am. Chem. Soc., 110, 2008.
26. Absalon, M.J., Krishnamoorthy, C.R., McGall, G., Kozarich, J.W. and Stubbe, J. (1992) Nucleic Acids Res., 20, 4179.
27. Morgan, M.A. and Hecht, S.M. (1994) Biochemistry, 33, 10286-10293.
28. Magliozzo, R.S., Peisach, J. and Ciriolo, M.R. (1989) Mol. Pharmacol., 35, 428-432.
29. Carter, B.J., de Vroom, E., Long, E.C., van der Marcel, G.A., van Boom, J.H. and Hecht, S.M. (1990) Proc. Natl. Acad. Sci. USA, 87, 9373.
30. Zeng, X., Xi, Z., Kappen, L.S., Tan, W. and Goldberg, I.H. (1995) Biochemistry, 34, 12435.
31. Zhang, G. (1993) Doctoral dissertation, University of Maryland.
32. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd Edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
33. Maxam, A.M. and Gilbert, W. (1980) Methods Enzymol., 65, 499.
34. Stubbe, J. and Kozarich, J.W. (1987) Chem. Rev., 87, 1107.
35. Poon, R., Beerman, T.A. and Goldberg, I.H. (1977) Biochemistry, 16, 486.
36. Sugiura, Y., Uesawa, Y., Takahashi, Y., Kuwahara, J., Golik, J. and Doyle, T.W. (1989) Proc. Natl. Acad. Sci USA, 86, 7672.
37. Lu, M., Guo, Q., Krishnan, B., Golik J., Rosenberg, I.E., Doyle, T.W. and Kallenbach, N.R. (1991) J. Biomol. Struct. Dyn., 9, 285.
38. Takeshita, M., Grollman, A.P., Ohtsubo, E. and Ohtsubo, H. (1978) Proc. Natl. Acad. Sci USA, 15, 5983.
39. D'Andrea, A. and Haseltine, W.A. (1978) Proc. Natl. Acad. Sci USA, 75, 3608.
40. Murray, V. and Martin, R.F. (1985) Nucleic Acids Res., 13, 1467.
41. Kuwahara, J. and Sugiura, Y. (1988) Proc. Natl. Acad. Sci. USA, 85, 2459.
42. Wu, W., Vanderwall, D.E., Lui, S.M., Tang, X.-J., Turner, C.J., Kozarich, J.W. and Stubbe, J. (1996) J. Am. Chem. Soc., 118, 1268-1280.
43. Wu, W., Vanderwall, D.E., Turner, C.J., Kozarich, J.W. and Stubbe, J. (1996) J. Am. Chem. Soc., 118, 1281-1294.
44. Stubbe, J., Kozarich, J.W., Wu, W. and Vanderwall, D.E. (1996) Acc. Chem. Res., 29, 322-330.
45. Bansal, M., Stubbe, J. and Kozarich, J.W. (1997) Nucleic Acids Res., 25, 1846-1853.
46. Mei, H.-Y. and Barton J.K. (1988) Proc. Natl. Acad. Sci. USA, 85, 1339.
47. Amott, S., Chandrasekaran, R., Millane, R.P. and Park, H.-S. (1986) J. Mol. Biol., 188, 631-640.
48. Salazar, M., Oleg, Y.F., Miller, J.M., Ribeiro, N.S. and Reid, B.R. (1993) Biochemistry, 32, 4207.