Dietary antioxidant supplementation did not affect declining sperm function with age in the mouse but did increase head abnormalities and reduced sperm production

Reproduction Nutrition Development

Volumn 37, Issue 5, 1997, Pages 481-492

  Ten, J ^a   Vendrell, F J ^a   Cano, A ^a   Tarin J J ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

Author keywords

Dietary supplementation; In vitro fertilization; Paternal age; Sperm quality; Vitamins C and E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ARTIFICIAL INSEMINATION; CONTROLLED STUDY; DIET SUPPLEMENTATION; EPIDIDYMIS; FERTILIZATION IN VITRO; LEYDIG CELL; MALE; MALE FERTILITY; MOUSE; NONHUMAN; OOCYTE; PATERNAL AGE; SERTOLI CELL; SPERM; SPERMATOGENESIS; SPERMATOZOON COUNT; STEROIDOGENESIS;

ANIMALIA;

EID: 0030730373     PISSN: 09265287     EISSN: None     Source Type: Journal    
DOI: 10.1051/rnd:19970501     Document Type: Article

References (38)

1. Auroux M, Nawar NN, Rizkalla N (1985) Testicular aging: vascularization and gametogenesis: modifications in the Wistar rat. Arch Androl 14, 115-121
2. Bronson FH, Desjardins C (1977) Reproductive failure in aged CBF1 male mice: interrelationships between pituitary gonadotropic hormones, testicular function, and mating success. Endocrinology 101, 939-945
3. Cummins JM, Jequier AM, Kan R (1994) Molecular biology of human male infertility: links with aging, mitochondnal genetics, and oxidative stress? Mol Reprod Dev 37, 345-362
4. Dawson EB, Harris WA, Rankin WE, Charpentier LA, McGanity WJ (1987) Effect of ascorbic acid on male fertility. Ann NY Acad Sci 498, 313-323
5. Dawson EB, Harris WA, Teter MC, Powell LC (1992) Effect of ascorbic acid supplementation on the sperm qualities of smokers. Fertil Steril 58, 1034-1039
6. De-la-Asunción JG, Milian A, Pla R, Bruseghini L, Esteras A, Pallardó FV, Sastre J, Viña J (1996) Mitochondrial glutathione oxidation correlates with age-associated oxidative damage to mitochondrial DNA. FASEB J 10, 333-338
7. Fraga CG, Motchnik PA, Shigenaga MK, Helbock HJ, Jacob RA, Ames BN (1991) Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci USA 88, 11003-11006
8. Geva E, Bartoov B, Zabludovsky N, Lessing JB, Lerner-Geva L, Amit A (1996) The effect of antioxidant treatment on human spermatozoa and fertilization rate in an in vitro fertilization program. Fertil Steril 66, 430-434
9. Gosden RG, Richardson DW, Brown N, Davidson DW (1982) Structure and gametogenic potential of seminiferous tubules in ageing mice. J Reprod Fertil 64, 127-133
10. Harman D (1956) Aging: a theory based on free radical and radiation chemistry. J Gerontol 11, 298-300
11. Harman D (1981) The aging process. Proc Natl Acad Sci USA 78, 7124-7128
12. Herbert V (1994) The antioxidant supplement myth. Am J Clin Nutr 60, 157-158
13. Herbert V (1996) Prooxidant effects of antioxidants vitamins. J Nutr 126, 1197S-1200S
14. Janny L, Menezo YJ (1994) Evidence for a strong paternal effect on human preimplantation embryo development and blastocyst formation Mol Reprod Dev 38, 36-42
15. Johnson L (1986) Spermatogenesis and aging in the human. J Androl 7, 331-354
16. Johnson L (1989) Evaluation of the human testis and its age-related dysfunction. Prog Clin Biol Res 302, 35-67
17. Johnson L, Petty CS, Porter JC, Neaves WB (1984) Germ cell degeneration during postprophase of meiosis and serum concentrations of gonadotropins in young adult and older adult men Biol Reprod 31, 779-784
18. Kessopoulou E, Powers HJ, Sharma KK, Pearson MJ, Russell JM, Cooke ID, Barratt CLR (1995) A double-blind randomized placebo cross-over controlled trial using the antioxidant vitamin E to treat reactive oxygen species associated male infertility. Fertil Steril 64, 825-831
19. Kinoshita T, Higashi Y, Winters S, Oshima H, Troen P (1985) An analysis of the age-related decline in testicular steriodogenesis in the rat Biol Reprod 32, 309-314
20. Kot MC, Handel MA (1987) Binding of morphologically abnormal sperm to mouse egg zonae pellucidae in vitro Gamete Res 18, 57-66
21. Kruger TF, Acosta AA, Simmons KF, Swanson RJ, Matta JF, Oehninger S (1988) Predictive value of abnormal sperm morphology in in vitro fertilization. Fertil Steril 49, 112
22. Krzanowska H (1981) Sperm head abnormalities in relation to the age and strain of mice. J Reprod Fert 62, 385-392
23. Krzanowska H, Lorenc E (1983) Influence of egg investments on in-vitro penetration of mouse eggs by misshapen spermatozoa. J Reprod Fert 68, 57-62
24. Levine L, Morita K (1985) Ascorbic acid in endocrine systems. Vit Horm 42, 1-64
25. Lynch KM, Scott WW (1950) The lipid content of the Leydig cell and the Sertoli cell in the human testis as related to age, benign hypertrophy and prostatic cancer. J Urol 64, 767-776
26. Menkveld R, Franken DR, Kruger TF, Oehninger S, Hodgen GD (1991) Sperm selection capacity of the human zona pellucida. Mol Reprod Dev 30, 346-352
27. Miquel J, Fleming J (1986) Theoretical and experimental support for an oxygen radical mitochondrial injury hypothesis of cell aging. In: Free Radicals, Aging, and Degenerative Diseases (JE Johnson, R Walford, D Harman, J Miquel, eds), Alan R Liss Inc, New York, 51-74
28. Paniagua R, Rodriguez MC, Nistal M. Fraile B, Amat P (1987) Changes in the lipid inclusion/Sertoli cell cytoplasm area ratio during the cycle of the human seminiferous epithelium. J Reprod Fertil 80, 335-341
29. Parinaud J, Mieusset R, Vieitez G, Labal B, Richoilley G (1993) Influence of sperm parameters on embryo quality. Fertil Steril 60, 888-892
30. Parkening TA (1989) Fertilizing ability of spermatozoa from aged C57BL/6NNia mice. J Reprod Fert 87, 727-733
31. Parkening TA, Collins TJ, Au WW (1988) Paternal age and ils effects on reproduction in C57BL/6NNia mice. J Gerontol 43, B79-84
32. Quinn P, Barros C, Whittingham DG (1982) Preservation of hamster oocytes to assay the fertilizing capacity of human spermatozoa J Reprod Fertil 66, 161-168
33. Ron-El R, Nachum H, Herman A, Golan A, Caspi E, Soffer Y (1991) Delayed fertilization and poor embryonic development associated with impaired semen quality. Fertil Steril 55, 338-344
34. Schwartz JL (1996) The dual roles of nutrients as antioxidants and prooxidants: their effects on tumor cell growth. J Nutr 126, 1221S-1227S
35. Shigenaga MK, Hagen TM, Ames BN (1994) Oxidative damage and mitochondrial decay in aging. Proc Natl Acad Sci USA 91, 10771-10778
36. Takano H, Abe K (1987) Age-related histologic changes in the adult mouse testis. Arch Histol Jpn 50, 533-544
37. Whittingham DG (1971) Culture of mouse ova. J Reprod Fertil 14, 7S-21S
38. Zenzes MT, Belkien L, Bordt J, Kan Y, Schneider HPG, Nieschlag E (1985) Cytologic investigation of human in vitro fertilization failures Fertil Steril 43, 883