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Volumn 15, Issue 5, 1997, Pages 356-362

Application of an expert system in the management of HIV-infected patients

Author keywords

AIDS; Antiretrovirals; Cloning; Expert program; PCR; Sequencing

Indexed keywords

ANTIRETROVIRUS AGENT; DELAVIRDINE; DIDANOSINE; INDINAVIR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; RITONAVIR; SAQUINAVIR; STAVUDINE; ZALCITABINE; ZIDOVUDINE;

EID: 0030723424     PISSN: 10779450     EISSN: None     Source Type: Journal    
DOI: 10.1097/00042560-199708150-00005     Document Type: Article
Times cited : (15)

References (51)
  • 1
    • 0028941196 scopus 로고
    • Antiviral therapy for human immunodeficiency virus infections
    • DeClercq E. Antiviral therapy for human immunodeficiency virus infections. Clin Microbiol Rev 1995;8:200-39.
    • (1995) Clin Microbiol Rev , vol.8 , pp. 200-239
    • DeClercq, E.1
  • 2
    • 0028326710 scopus 로고
    • Quasispecies dynamics and the emergence of drug resistance during zidovudine therapy of HIV infection
    • Frost S, McLean A. Quasispecies dynamics and the emergence of drug resistance during zidovudine therapy of HIV infection. AIDS 1994;8:323-32.
    • (1994) AIDS , vol.8 , pp. 323-332
    • Frost, S.1    McLean, A.2
  • 3
    • 8944225025 scopus 로고    scopus 로고
    • Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients
    • Katlama C, Ingrand D, Loveday C, et al. Safety and efficacy of lamivudine-zidovudine combination therapy in antiretroviral-naive patients. JAMA 1996;276:118-25.
    • (1996) JAMA , vol.276 , pp. 118-125
    • Katlama, C.1    Ingrand, D.2    Loveday, C.3
  • 4
    • 0027481325 scopus 로고
    • Measurement of HIV virus load and genotypic resistance by gene amplification in asymptomatic subjects treated with combination therapy
    • Holodniy M, Katzenstein D, Winters M, et al. Measurement of HIV virus load and genotypic resistance by gene amplification in asymptomatic subjects treated with combination therapy. J Acquir Immune Defic Syndr 1993;6:366-9.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 366-369
    • Holodniy, M.1    Katzenstein, D.2    Winters, M.3
  • 5
    • 0026732684 scopus 로고
    • A controlled trial comparing zidovudine with didanosine in human immunodeficiency virus infection: The NIAID AIDS Clinical Trials Group
    • Kahn J, Lagakos S, Richman D, et al. A controlled trial comparing zidovudine with didanosine in human immunodeficiency virus infection: The NIAID AIDS Clinical Trials Group. N Engl J Med 1992;327:581-7.
    • (1992) N Engl J Med , vol.327 , pp. 581-587
    • Kahn, J.1    Lagakos, S.2    Richman, D.3
  • 6
    • 9444290697 scopus 로고    scopus 로고
    • Virologic and immunologic benefits of initial combination therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy: Wellcome Resistance Study Collaborative Group
    • Schooley RT, Ramirez-Ronda C, Lange JM, et al. Virologic and immunologic benefits of initial combination therapy with zidovudine and zalcitabine or didanosine compared with zidovudine monotherapy: Wellcome Resistance Study Collaborative Group. J Infect Dis 1996;173:1354-66.
    • (1996) J Infect Dis , vol.173 , pp. 1354-1366
    • Schooley, R.T.1    Ramirez-Ronda, C.2    Lange, J.M.3
  • 7
    • 0029867822 scopus 로고    scopus 로고
    • Drug combinations and effect parameters of zidovudine, stavudine, and nevirapine in standardized drug-sensitive and resistant HIV type 1 strains
    • Zhu QY, Scarborough A, Polsky B, Chou TC. Drug combinations and effect parameters of zidovudine, stavudine, and nevirapine in standardized drug-sensitive and resistant HIV type 1 strains. AIDS Res Hum Retroviruses 1996;12:507-17.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 507-517
    • Zhu, Q.Y.1    Scarborough, A.2    Polsky, B.3    Chou, T.C.4
  • 9
    • 0029984169 scopus 로고    scopus 로고
    • Development of resistance to zidovudine (ZDV) and didanosine (ddl) in HIV from patients in ZDV, ddl and alternating ZDV/ddl therapy
    • Nielsen C, Bruun L, Mathiesen L, Pedersen C, Gerstoft J. Development of resistance to zidovudine (ZDV) and didanosine (ddl) in HIV from patients in ZDV, ddl and alternating ZDV/ddl therapy. AIDS 1996;10:625-33.
    • (1996) AIDS , vol.10 , pp. 625-633
    • Nielsen, C.1    Bruun, L.2    Mathiesen, L.3    Pedersen, C.4    Gerstoft, J.5
  • 10
    • 0026036042 scopus 로고
    • Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes
    • Larder B, Kellam P, Kemp S. Zidovudine resistance predicted by direct detection of mutations in DNA from HIV-infected lymphocytes. AIDS 1991;5:137-44.
    • (1991) AIDS , vol.5 , pp. 137-144
    • Larder, B.1    Kellam, P.2    Kemp, S.3
  • 11
    • 0024310253 scopus 로고
    • Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT)
    • Larder B, Kemp S. Multiple mutations in HIV-1 reverse transcriptase confer high-level resistance to zidovudine (AZT). Science 1989;246:1155-8.
    • (1989) Science , vol.246 , pp. 1155-1158
    • Larder, B.1    Kemp, S.2
  • 12
    • 0028796387 scopus 로고
    • Specific, sensitive, and rapid assay for HIV pol mutations associated with resistance to zidovudine and didanosine
    • Frenkel L, Wagner M, Atwood S, Cummins T, Dewhurst S. Specific, sensitive, and rapid assay for HIV pol mutations associated with resistance to zidovudine and didanosine. J Infect Dis 1995; 33:342-7.
    • (1995) J Infect Dis , vol.33 , pp. 342-347
    • Frenkel, L.1    Wagner, M.2    Atwood, S.3    Cummins, T.4    Dewhurst, S.5
  • 14
    • 8844261754 scopus 로고
    • The utility of knowledge in inductive learning
    • Pazzani M, Kibler D. The utility of knowledge in inductive learning. Machine Learning 1992;9:57-94.
    • (1992) Machine Learning , vol.9 , pp. 57-94
    • Pazzani, M.1    Kibler, D.2
  • 15
    • 0026565278 scopus 로고
    • Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
    • Kellam P, Boucher C, Larder BA. Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine. Proc Natl Acad Sci USA 1992;89:1934-8.
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 1934-1938
    • Kellam, P.1    Boucher, C.2    Larder, B.A.3
  • 16
    • 0026803394 scopus 로고
    • PCR amplification of HIV-1 proteinase sequences directly from lab isolates allows determination of five conserved domains
    • Fontenant G, Johnston K, Cohen J, Gallaher W, Robinson J, Luftig R. PCR amplification of HIV-1 proteinase sequences directly from lab isolates allows determination of five conserved domains. Virol 1992;190:1-10.
    • (1992) Virol , vol.190 , pp. 1-10
    • Fontenant, G.1    Johnston, K.2    Cohen, J.3    Gallaher, W.4    Robinson, J.5    Luftig, R.6
  • 17
    • 0028057581 scopus 로고
    • Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2′,3′-dideoxycytidine and 2′,3′-dideoxy-3′-thiacytidine
    • Gu Z, Gao Q, Fang H, et al. Identification of a mutation at codon 65 in the IKKK motif of reverse transcriptase that encodes human immunodeficiency virus resistance to 2′,3′-dideoxycytidine and 2′,3′-dideoxy-3′-thiacytidine. Antimicrob Agents Chemother 1994;38:275-81.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 275-281
    • Gu, Z.1    Gao, Q.2    Fang, H.3
  • 18
    • 0023734473 scopus 로고
    • Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases
    • Clark J. Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases. Nucleic Acid Res 1988;20:9677-86.
    • (1988) Nucleic Acid Res , vol.20 , pp. 9677-9686
    • Clark, J.1
  • 19
    • 0026623164 scopus 로고
    • Rapid sequencing of the Sendai virus 6.8 kb large (L) gene through primer walking with an automated DNA sequencer
    • Giesecke H, Obermaier B, Domdey H. Rapid sequencing of the Sendai virus 6.8 kb large (L) gene through primer walking with an automated DNA sequencer. J Virol Methods 1992;38:47-60.
    • (1992) J Virol Methods , vol.38 , pp. 47-60
    • Giesecke, H.1    Obermaier, B.2    Domdey, H.3
  • 20
    • 0025950055 scopus 로고
    • Resistance to ddl and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase
    • St Clair M, Martin J, Tudor W. Resistance to ddl and sensitivity to AZT induced by a mutation in HIV-1 reverse transcriptase. Science 1991;253:1557-9.
    • (1991) Science , vol.253 , pp. 1557-1559
    • St Clair, M.1    Martin, J.2    Tudor, W.3
  • 21
    • 0026465275 scopus 로고
    • Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2′,3′-dideoxyinosine and 2′,3′-dideoxycytidine
    • Gu Z, Gao Q, Li X, Parniak M, Wainberg M. Novel mutation in the human immunodeficiency virus type 1 reverse transcriptase gene that encodes cross-resistance to 2′,3′-dideoxyinosine and 2′,3′-dideoxycytidine. J Virol 1992;66:7128-35.
    • (1992) J Virol , vol.66 , pp. 7128-7135
    • Gu, Z.1    Gao, Q.2    Li, X.3    Parniak, M.4    Wainberg, M.5
  • 22
    • 0042064823 scopus 로고
    • Identification of novel mutations that confer drug resistance in the human immunodeficiency virus polymerase gene
    • Gu Z, Gao Q, Fang H, Parniak M, Brenner B, Wainberg M. Identification of novel mutations that confer drug resistance in the human immunodeficiency virus polymerase gene. Leukemia 1994; 851:5166-9.
    • (1994) Leukemia , vol.851 , pp. 5166-5169
    • Gu, Z.1    Gao, Q.2    Fang, H.3    Parniak, M.4    Brenner, B.5    Wainberg, M.6
  • 23
    • 0026318387 scopus 로고
    • Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture
    • Richman D, Shin C, Lowy I, Rose J, Prodanovich P, Goff S, Griffin J. Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. Proc Natl Accid Sci USA 1991;88:11241-5.
    • (1991) Proc Natl Accid Sci USA , vol.88 , pp. 11241-11245
    • Richman, D.1    Shin, C.2    Lowy, I.3    Rose, J.4    Prodanovich, P.5    Goff, S.6    Griffin, J.7
  • 24
    • 0028013171 scopus 로고
    • Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor
    • El-Farrash M, Kuroda M, Kitazaki T, Masuda T, Kato K, Hatanaka M, Harada S, Generation and characterization of a human immunodeficiency virus type 1 (HIV-1) mutant resistant to an HIV-1 protease inhibitor. J Virol 1994;68:233-9.
    • (1994) J Virol , vol.68 , pp. 233-239
    • El-Farrash, M.1    Kuroda, M.2    Kitazaki, T.3    Masuda, T.4    Kato, K.5    Hatanaka, M.6    Harada, S.7
  • 25
    • 0027231438 scopus 로고
    • A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other non-nucleoside inhibitors
    • Dueweke T, Pushkarskaya T, Poppe S, et al. A mutation in reverse transcriptase of bis(heteroaryl)piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other non-nucleoside inhibitors. Proc Natl Acad Sci USA 1993;90: 4713-7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4713-4717
    • Dueweke, T.1    Pushkarskaya, T.2    Poppe, S.3
  • 26
    • 0027986621 scopus 로고
    • Issues in combination antiretroviral therapy: A review
    • Hammer S, Kessler H, Saag M. Issues in combination antiretroviral therapy: a review. J Acquir Immune Defic Syndr 1994;7 Suppl 2:524-35.
    • (1994) J Acquir Immune Defic Syndr , vol.7 , Issue.2 SUPPL. , pp. 524-535
    • Hammer, S.1    Kessler, H.2    Saag, M.3
  • 27
    • 0029019919 scopus 로고
    • Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudinedidanosine combination therapy
    • Holodniy M, Mole L, Margolis D, et al. Determination of human immunodeficiency virus RNA in plasma and cellular viral DNA genotypic zidovudine resistance and viral load during zidovudinedidanosine combination therapy. J Virol 1995;69:3510-6.
    • (1995) J Virol , vol.69 , pp. 3510-3516
    • Holodniy, M.1    Mole, L.2    Margolis, D.3
  • 28
    • 0029671077 scopus 로고    scopus 로고
    • V3 seroreactivity and sequence variation: Tracking the emergence of V3 genotypic variation in HIV-1-infected patients
    • Michael N, Davis KE, Loomis-Price L, VanCott T, Burke D, Redfield R, Birx D. V3 seroreactivity and sequence variation: Tracking the emergence of V3 genotypic variation in HIV-1-infected patients. AIDS 1996;10:121-9.
    • (1996) AIDS , vol.10 , pp. 121-129
    • Michael, N.1    Davis, K.E.2    Loomis-Price, L.3    Vancott, T.4    Burke, D.5    Redfield, R.6    Birx, D.7
  • 29
    • 0031022049 scopus 로고    scopus 로고
    • Analysis of differential display RT-PCR products using fluorescent primers and GENESCAN software
    • Luehrsen KR, Marr L, van der Knaap E, Cumberledge S. Analysis of differential display RT-PCR products using fluorescent primers and GENESCAN software. Biotechniques 1997;22:168-74.
    • (1997) Biotechniques , vol.22 , pp. 168-174
    • Luehrsen, K.R.1    Marr, L.2    Van Der Knaap, E.3    Cumberledge, S.4
  • 31
    • 0026570624 scopus 로고
    • Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive patients
    • Boucher C, O'Sullivan E, Mulder A, et al. Ordered appearance of zidovudine resistance mutations during treatment of 18 human immunodeficiency virus-positive patients. J Infect Dis 1992; 165: 105-10.
    • (1992) J Infect Dis , vol.165 , pp. 105-110
    • Boucher, C.1    O'Sullivan, E.2    Mulder, A.3
  • 32
    • 0028997461 scopus 로고
    • Reverse transcriptase mutations in sequential HIV-1 isolates in a patient with AIDS
    • Gurusinghe A, Land S, Birch C, et al. Reverse transcriptase mutations in sequential HIV-1 isolates in a patient with AIDS. J Med Virol 1995;46:238-43.
    • (1995) J Med Virol , vol.46 , pp. 238-243
    • Gurusinghe, A.1    Land, S.2    Birch, C.3
  • 33
    • 0030004944 scopus 로고    scopus 로고
    • Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication
    • Caliendo A, Savara A, An D, DeVore K, Kaplan J, D'Aquila R. Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication, J Virol 1996;70:2146-53.
    • (1996) J Virol , vol.70 , pp. 2146-2153
    • Caliendo, A.1    Savara, A.2    An, D.3    DeVore, K.4    Kaplan, J.5    D'Aquila, R.6
  • 34
    • 0029896847 scopus 로고    scopus 로고
    • Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2′-dideoxy-3′-thiacytidine by mutated M184V human immunodeficiency virus type 1
    • Quan Y, Gu Z, Li X, Li Z, Morrow C, Wainberg M. Endogenous reverse transcription assays reveal high-level resistance to the triphosphate of (-)2′-dideoxy-3′-thiacytidine by mutated M184V human immunodeficiency virus type 1. J Virol 1996;70:5642-5.
    • (1996) J Virol , vol.70 , pp. 5642-5645
    • Quan, Y.1    Gu, Z.2    Li, X.3    Li, Z.4    Morrow, C.5    Wainberg, M.6
  • 35
    • 0030048748 scopus 로고    scopus 로고
    • Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy
    • Iversen AK, Shafer RW, Wearly K, Winters MA, Mullins JI, Chesebro B, Morgan TC. Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy. J Virol 1996;70:1086-90.
    • (1996) J Virol , vol.70 , pp. 1086-1090
    • Iversen, A.K.1    Shafer, R.W.2    Wearly, K.3    Winters, M.A.4    Mullins, J.I.5    Chesebro, B.6    Morgan, T.C.7
  • 36
    • 10244227943 scopus 로고    scopus 로고
    • An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3′-azido-3′-deoxythymidine
    • Hooker D, Tachedjian G, Soloman A, et al. An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3′-azido-3′-deoxythymidine. J Virol 1996;70:8010-8.
    • (1996) J Virol , vol.70 , pp. 8010-8018
    • Hooker, D.1    Tachedjian, G.2    Soloman, A.3
  • 37
    • 0030006621 scopus 로고    scopus 로고
    • The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptse displays a broader cross-resistance that extends to nonnucleoside inhibitors
    • Kew Y, Saloman H, Olsen L, Wainberg M, Prasad V. The nucleoside analog-resistant E89G mutant of human immunodeficiency virus type 1 reverse transcriptse displays a broader cross-resistance that extends to nonnucleoside inhibitors. Antimicrob Agents Chemother 1996;40:1711-4.
    • (1996) Antimicrob Agents Chemother , vol.40 , pp. 1711-1714
    • Kew, Y.1    Saloman, H.2    Olsen, L.3    Wainberg, M.4    Prasad, V.5
  • 38
    • 0029867822 scopus 로고    scopus 로고
    • Drug combinations and effect parameters of zidovudine, stavudine, and nevirapine in standardized drug-sensitive and resistant HIV type 1 strains
    • Zhu Q, Scarborough A, Polsky B, Chou T. Drug combinations and effect parameters of zidovudine, stavudine, and nevirapine in standardized drug-sensitive and resistant HIV type 1 strains. AIDS Res Hum Retroviruses 1996;12:507-17.
    • (1996) AIDS Res Hum Retroviruses , vol.12 , pp. 507-517
    • Zhu, Q.1    Scarborough, A.2    Polsky, B.3    Chou, T.4
  • 39
    • 0027957791 scopus 로고
    • Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy
    • Richman D, Havlir D, Corbeil J, et al. Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy. J Virol 1994;68:1660-6.
    • (1994) J Virol , vol.68 , pp. 1660-1666
    • Richman, D.1    Havlir, D.2    Corbeil, J.3
  • 40
    • 0027278781 scopus 로고
    • Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents
    • Richman DD. Resistance of clinical isolates of human immunodeficiency virus to antiretroviral agents. Antimicrob Agents Chemother 1993;37:1207-13.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 1207-1213
    • Richman, D.D.1
  • 41
    • 0026318387 scopus 로고
    • Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture
    • Richman D, Shih CK, Lowy I, Rose J, Prodanovich P, Goff S, Griffin J. Human immunodeficiency virus type 1 mutants resistant to nonnucleoside inhibitors of reverse transcriptase arise in tissue culture. Proc Natl Acad Sci USA 1991;88:11241-5.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11241-11245
    • Richman, D.1    Shih, C.K.2    Lowy, I.3    Rose, J.4    Prodanovich, P.5    Goff, S.6    Griffin, J.7
  • 42
    • 0029798237 scopus 로고    scopus 로고
    • Nevirapine-resistant human immnodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients
    • Havlir, Eastman S, Gamst A, Richman D. Nevirapine-resistant human immnodeficiency virus: Kinetics of replication and estimated prevalence in untreated patients. J Virol 1996;70:7894-9.
    • (1996) J Virol , vol.70 , pp. 7894-7899
    • Havlir1    Eastman, S.2    Gamst, A.3    Richman, D.4
  • 43
    • 0027231438 scopus 로고
    • A mutation in reverse transcriptase of bis(heteroaryl) piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other non-nucleoside inhibitors
    • Dueweke TJ, Pushkarskaya T, Poppe SM, et al. A mutation in reverse transcriptase of bis(heteroaryl) piperazine-resistant human immunodeficiency virus type 1 that confers increased sensitivity to other non-nucleoside inhibitors. Proc Natl Acad Sci USA 1993;90: 4713-7.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 4713-4717
    • Dueweke, T.J.1    Pushkarskaya, T.2    Poppe, S.M.3
  • 44
    • 0028014288 scopus 로고
    • Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetic protease inhibitor
    • Ho DD, Toyoshima T, Mo H, et al. Characterization of human immunodeficiency virus type 1 variants with increased resistance to a C2-symmetic protease inhibitor. J Virol 1994;68:2016-2020.
    • (1994) J Virol , vol.68 , pp. 2016-2020
    • Ho, D.D.1    Toyoshima, T.2    Mo, H.3
  • 45
    • 0028286025 scopus 로고
    • Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of viral protease
    • Kaplan AH, Michael SF, Wehbie RS, et al. Selection of multiple human immunodeficiency virus type 1 variants that encode viral proteases with decreased sensitivity to an inhibitor of viral protease. Proc Natl Acad Sci USA 1994;91:5597-601.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5597-5601
    • Kaplan, A.H.1    Michael, S.F.2    Wehbie, R.S.3
  • 46
    • 0029806127 scopus 로고    scopus 로고
    • Rational approaches to resistance using saquinavir
    • Boucher C. Rational approaches to resistance using saquinavir. AIDS 1996;10(suppl 1):S15-9.
    • (1996) AIDS , vol.10 , Issue.1 SUPPL.
    • Boucher, C.1
  • 47
    • 0030012398 scopus 로고    scopus 로고
    • Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538)
    • Schmidt J, Ruiz L, Clotet B, et al. Resistance-related mutations in the HIV-1 protease gene of patients treated for 1 year with the protease inhibitor ritonavir (ABT-538). AIDS 1996;10:995-9.
    • (1996) AIDS , vol.10 , pp. 995-999
    • Schmidt, J.1    Ruiz, L.2    Clotet, B.3
  • 48
    • 10344263394 scopus 로고    scopus 로고
    • Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor
    • Condra J, Holder D, Schlief W, et al. Genetic correlates of in vivo viral resistance to indinavir, a human immunodeficiency virus type 1 protease inhibitor. J Virol 1996;70:8270-6.
    • (1996) J Virol , vol.70 , pp. 8270-8276
    • Condra, J.1    Holder, D.2    Schlief, W.3
  • 49
    • 12644277366 scopus 로고    scopus 로고
    • Genotypic analysis of HIV-1 variants isolated from patients treated with the protease inhibitor Nelfinavir, alone or in combination with d4T or AZT and 3TC
    • [Abstract]. Washington, DC
    • Patick A, Duran M, Cao Y, et al. Genotypic analysis of HIV-1 variants isolated from patients treated with the protease inhibitor Nelfinavir, alone or in combination with d4T or AZT and 3TC [Abstract]. Presented at the Fourth Conference on Retroviruses and Opportunistic Infections, Washington, DC, 1997.
    • (1997) Fourth Conference on Retroviruses and Opportunistic Infections
    • Patick, A.1    Duran, M.2    Cao, Y.3
  • 51
    • 0029974261 scopus 로고    scopus 로고
    • Drug interactions with antiviral drugs
    • Taburet A, Singlas E. Drug interactions with antiviral drugs. Clin Pharmacokinet 1996;30:385-401.
    • (1996) Clin Pharmacokinet , vol.30 , pp. 385-401
    • Taburet, A.1    Singlas, E.2


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