Expression of CD40 induces neural apoptosis

Journal of Neuroscience Research

Volumn 50, Issue 3, 1997, Pages 383-390

  Ruan, Youlin ^a   Rabizadeh, Shahrooz ^b,c   Camerini, David ^d   Bredesen, Dale E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BURNHAM INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Apoptosis; CD40; Tumor necrosis factor receptor

Indexed keywords

CD40 ANTIGEN; MONOCLONAL ANTIBODY; TUMOR NECROSIS FACTOR RECEPTOR;

ANIMAL CELL; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; CELL DEATH; DRUG RECEPTOR BINDING; ENZYME INHIBITION; GENE INDUCTION; LIGAND BINDING; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS INHIBITION; RECEPTOR AFFINITY;

ANIMALS; ANTIGENS, CD40; APOPTOSIS; AVIAN SARCOMA VIRUSES; BRAIN; CELL LINE, TRANSFORMED; CELL SURVIVAL; HUMANS; KINETICS; NEURONS; RATS; RECEPTOR, NERVE GROWTH FACTOR; RECEPTORS, NERVE GROWTH FACTOR; RECOMBINANT PROTEINS; TIME FACTORS; TRANSFECTION;

EID: 0030714157     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4547(19971101)50:3<383::AID-JNR4>3.0.CO;2-E     Document Type: Article

References (35)

1. Barrett G, Bartlett P (1994): The p75 nerve growth factor receptor mediates survival or death depending on the stage of sensory neuron development. Proc Natl Acad Sci USA 91:6501-6505.
2. NGFR mediates death of PC12 cells after nerve growth factor withdrawal. J Neurosci Res 45:117-128.
3. Casaccia-Bonnefil P, Carter BD, Dobrowsky RT, Chao MV (1996): Death of oligodendrocytes mediated by the interaction of nerve growth factor with its receptor p75. Nature 383:716-719.
4. Chen YC, Hayman MJ, Vogt PK (1977): Properties of mammalian cells transformed by temperature-sensitive mutants of avian sarcoma virus. Cell 11:513-521.
5. Cheng G, Cleary AM, Ye Z, Hong DI, Lederman S, Baltimore D (1995): Involvement of CRAF1, a relative of TRAF, in CD40 signaling. Science 267:1494-1498.
6. Cortazzo MH, Kassis ES, Sproul KA, Schor NF (1996): Nerve growth factor (NGF)-mediated protection of neural crest cells from antimitotic agent-induced apoptosis: the role of the low-affinity NGF receptor. J Neurosci 16:3895-3899.
7. Cotman CW, Pike CJ, Copani A (1992): β-Amyloid neurotoxicity: a discussion of in vitro findings. Neurobiol Aging 13:587-590.
8. Desai DM, Sap J, Schlessinger J, Weiss A (1993): Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell 73:541-554.
9. Ellerby HM, Martin SJ, Ellerby LM, Naiem SS, Rabizadeh S, Salvesen GS, Casiano CA, Cashman NR, Green DR, Bredesen DE (in press): Establishment of a cell-free system for neuronal apoptosis: comparison of pre-mitochondrial, mitochondrial, and post-mitochondrial phases. J. Neurosci.
10. Frade JM, Tebar AR, Barde Y (1996): Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383:166-168.
11. Gagliardini V, Fernandez P-A, Lee RKK, Drexler HCA, Rotello RJ, Fishman MC, Yuan J (1994): Prevention of vertebrate neuronal death by the crmA gene. Science 263:826-828.
12. Garcia I, Martinou I, Tsujimoto Y, Martinou JC (1992): Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene. Science 258:302-304.
13. Greenberg ME, Brackenbury R, Edelman GM (1984): Alteration of neural cell adhesion molecule (N-CAM) expression after neuronal cell transformation by Rous sarcoma virus. Proc Natl Acad Sci USA 81:969-973.
14. Hengartner MO, Horvitz HR (1994): C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian protooncogene bcl-2. Cell 76:665-676.
15. Hockenbery D, Nuez G, Milliman C, Schreiber R, Korsmeyer S (1990): Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature 348:334-336.
16. Itoh N, Nagata S (1993): A novel protein domain required for apoptosis. J Biol Chem 268:10932-10937.
17. Itoh N, Yonehara S, Ishii A, Yonehara M, Mizushima S, Sameshima M, Hase A, Seto Y, Nagata S (1991): The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 66:233-243.
18. Kerr JFR, Wyllie AH, Currie AR (1972): Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Brain J Cancer 26:239-257.
19. Linnik MD, Zobrist RH, Hatfield MD (1993): Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats. Stroke 24:2002-2009.
20. Liu YJ, Joshua DE, Williams GT, Smith CA, Gordon J, MacLennan IC (1989): Mechanism of antigen-driven selection in germinal centres. Nature 342:21-28.
21. Longo FM, Manthorpe M, Xie Y, Varon S (1996): Neurotrophic activity of synthetic NGF peptide derivatives. Soc Neurosci Abstr 22:557.
22. Man SP, Zhong LT, Liu Y, Roghani A, Edwards RH, Bredesen DE (1993): The protooncogene bcl-2 inhibits apoptosis in PC12 cells. J Neurochem 60:1183-1186.
23. Martin DP. Schmidt RE, deStefano PS, Lowry OH, Carter JG, Johnson EM (1988): Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation. J Cell Biol 106:829-844.
24. Miura M, Zhu H, Rotello R, Hartwieg, EA, Yuan J (1993): Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3. Cell 75:653-660.
25. Morgenstern JP, Land H (1990): Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line. Nucleic Acids Res 18:3587-3596.
26. Rabizadeh S, Bredesen DE (1994): Is p75NGFR involved in developmental neural cell death? Dev Neurosci 16:207-11.
27. Rabizadeh S, Oh J, Zhong L, Yang J, Bitler C, Butcher L, Bredesen DE (1993): Induction of apoptosis by the low-affinity NGF receptor. Science 261:345-348.
28. Rabizadeh S, Bitler CM, Butcher LL, Bredesen DE (1994): Expression of the low-affinity nerve growth factor receptor enhances β-amyloid peptide toxicity. Proc Natl Acad Sci USA 91:10703-10706.
29. Rothe M, Sarma V, Dixit VM, Goeddel DV (1995): TRAF2-mediated activation of NF-kB by TNF receptor 2 and CD40. Science 269:1424-1427.
30. Smith C, Davis T, Anderson D, Solam L, Beckmann M, Jerzy R, Dower S, Cosman D, Goodwin R (1990): A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. Science 248:1019-1023.
31. Stamenkovic I, Clark EA, Seed B (1989): A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. EMBO J 8:1403-1410.
32. trkA does not abolish nerve growth factor-mediated rescue of serum-free PC12 cells. J Neurochem 66: 1826-1835.
33. Taylor ICA, Roy S, Yaswen P, Stampfer MR, Varmus HE (1995): Mouse mammary tumors express elevated levels of RNA encoding the murine homolog of SKY, a putative receptor tyrosine kinase. J Biol Chem 268:6872-6880.
34. Thornberry NA, Bull HG, Calaycay JR, Chapman KT, Howard AD, Kostura MJ, Miller DK, Molineaux SM, Widner JR, Aunins J, Elliston KO, AyaCasano JM, Chin J, Ding JF, Egger LA, Gaffney EP, Limjuco G, Palyha OC, Raju SM, Rolando AM, Salley JP, Yamin T, Lee TD, Shively JE, MacCross MM, Mumford RA, Schmidt J, Tocci MJ (1992): A novel heterodimeric cysteine protease is required for interleukin-1B processing in monocytes. Nature 356:768-774.
35. Trauth BC, Klas C, Peters AM, Matzku S, Moller P, Falk W, Debatin KM, Krammer PH (1989): Monoclonal antibody-mediated tumor regression by induction of apoptosis. Science 245:301-305.