메뉴 건너뛰기




Volumn 3, Issue 11, 1997, Pages 1207-1219

Crosslinking of the U5 snRNP-specific 116-kDa protein to RNA hairpins that block step 2 of splicing

Author keywords

Crosslinking; Methylene blue; Pre mRNA splicing; U5 snRNP

Indexed keywords

RNA; RNA BINDING PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN;

EID: 0030694848     PISSN: 13558382     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (35)

References (66)
  • 1
    • 0344142407 scopus 로고
    • Identification of a functional mammalian spliceosome containing unspliced pre-mRNA
    • Abmayr SM, Reed R, Maniatis T. 1988. Identification of a functional mammalian spliceosome containing unspliced pre-mRNA. Proc Natl Acad Sci USA 85:7216-7220.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 7216-7220
    • Abmayr, S.M.1    Reed, R.2    Maniatis, T.3
  • 2
    • 0030802754 scopus 로고    scopus 로고
    • Bimolecular exon ligation by the human spliceosome
    • Anderson K, Moore MJ. 1997. Bimolecular exon ligation by the human spliceosome. Science 276:1712-1716.
    • (1997) Science , vol.276 , pp. 1712-1716
    • Anderson, K.1    Moore, M.J.2
  • 3
    • 0027205394 scopus 로고
    • The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation
    • Borman A, Howell MT, Patton JG, Jackson RJ. 1993. The involvement of a spliceosome component in internal initiation of human rhinovirus RNA translation. J Gen Virol 74:1775-1788.
    • (1993) J Gen Virol , vol.74 , pp. 1775-1788
    • Borman, A.1    Howell, M.T.2    Patton, J.G.3    Jackson, R.J.4
  • 4
    • 0028927643 scopus 로고
    • Genetic selection for balanced retroviral splicing: Novel regulation involving the second step can be mediated by transitions in the polypyrimidine tract
    • Bouck J, Fu XD, Skalka AM, Katz RA. 1995. Genetic selection for balanced retroviral splicing: Novel regulation involving the second step can be mediated by transitions in the polypyrimidine tract. Mol Cell Biol 15:2663-2671.
    • (1995) Mol Cell Biol , vol.15 , pp. 2663-2671
    • Bouck, J.1    Fu, X.D.2    Skalka, A.M.3    Katz, R.A.4
  • 5
    • 0022720942 scopus 로고
    • Yeast pre-messenger RNA splicing efficiency depends on critical spacing requirements between the branch point and 3′ splice site
    • Cellini AEF, Rossi JJ. 1986. Yeast pre-messenger RNA splicing efficiency depends on critical spacing requirements between the branch point and 3′ splice site. EMBO J 5:1023-1030.
    • (1986) EMBO J , vol.5 , pp. 1023-1030
    • Cellini, A.E.F.1    Rossi, J.J.2
  • 6
    • 0028260851 scopus 로고
    • Interaction between the first and last nucleotides of pre-mRNA introns is a determinant of 3′ splice site selection in S. cerevisiae
    • Chanfreau G, Legrain P, Dujon B, Jacquier A. 1994. Interaction between the first and last nucleotides of pre-mRNA introns is a determinant of 3′ splice site selection in S. cerevisiae. Nucleic Acids Res 22:1981-1987.
    • (1994) Nucleic Acids Res , vol.22 , pp. 1981-1987
    • Chanfreau, G.1    Legrain, P.2    Dujon, B.3    Jacquier, A.4
  • 7
    • 0029894931 scopus 로고    scopus 로고
    • Indentification of proteins that interact with exon sequences, splice sites, and the branchpoint sequence during each stage of spliceosome assembley
    • Chiara MD, Gozani O, Bennett M, Champion-Arnaud P, Palandjian L, Reed R. 1996. Indentification of proteins that interact with exon sequences, splice sites, and the branchpoint sequence during each stage of spliceosome assembley. Mol Cell Biol 16:3317-3326.
    • (1996) Mol Cell Biol , vol.16 , pp. 3317-3326
    • Chiara, M.D.1    Gozani, O.2    Bennett, M.3    Champion-Arnaud, P.4    Palandjian, L.5    Reed, R.6
  • 8
    • 0025780938 scopus 로고
    • Unexpected point mutations activate cryptic 3′ splice site by perturbing a natural secondary structure within a yeast intron
    • Deshler JO, Rossi JJ. 1991. Unexpected point mutations activate cryptic 3′ splice site by perturbing a natural secondary structure within a yeast intron. Genes & Dev 5:1252-1263.
    • (1991) Genes & Dev , vol.5 , pp. 1252-1263
    • Deshler, J.O.1    Rossi, J.J.2
  • 9
    • 0030976931 scopus 로고    scopus 로고
    • An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2
    • Fabrizio P, Laggperbauer B, Lauber J, Lane WS, Lührmann R. 1997. An evolutionarily conserved U5 snRNP-specific protein is a GTP-binding factor closely related to the ribosomal translocase EF-2. EMBO J 16:4092-4106.
    • (1997) EMBO J , vol.16 , pp. 4092-4106
    • Fabrizio, P.1    Laggperbauer, B.2    Lauber, J.3    Lane, W.S.4    Lührmann, R.5
  • 10
    • 0027981692 scopus 로고
    • Smooth muscle-specific switching of alpha-tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon
    • Gooding C, Roberts GC, Moreau G, Nadal Ginard B, Smith CWJ. 1994. Smooth muscle-specific switching of alpha-tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon. EMBO J 13:3861-3872.
    • (1994) EMBO J , vol.13 , pp. 3861-3872
    • Gooding, C.1    Roberts, G.C.2    Moreau, G.3    Nadal Ginard, B.4    Smith, C.W.J.5
  • 11
    • 0025099586 scopus 로고
    • In vitro splicing of mutually exclusive exons from the chicken β-tropomyosin gene: Role of the branch point and very long pyrimidine stretch
    • Goux-Pelletan M, Libri D, d'Aubenton-Carafa Y, Fiszman M, Brody E, Marie J. 1990. In vitro splicing of mutually exclusive exons from the chicken β-tropomyosin gene: Role of the branch point and very long pyrimidine stretch. EMBO J 9:241-249.
    • (1990) EMBO J , vol.9 , pp. 241-249
    • Goux-Pelletan, M.1    Libri, D.2    D'Aubenton-Carafa, Y.3    Fiszman, M.4    Brody, E.5    Marie, J.6
  • 12
    • 0028360767 scopus 로고
    • A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction
    • Gozani O, Patton JG, Reed R. 1994. A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction. EMBO J 13:3356-3367.
    • (1994) EMBO J , vol.13 , pp. 3356-3367
    • Gozani, O.1    Patton, J.G.2    Reed, R.3
  • 13
    • 0023004932 scopus 로고
    • Pre-mRNA splicing
    • Green MR. 1986 Pre-mRNA splicing. Annu Rev Genet 20:671-708.
    • (1986) Annu Rev Genet , vol.20 , pp. 671-708
    • Green, M.R.1
  • 14
    • 0023816617 scopus 로고
    • Impairment of yeast pre-mRNA splicing by potential secondary structure forming sequences near the conserved branchpoint sequence
    • Halfter H, Gallwitz D. 1988. Impairment of yeast pre-mRNA splicing by potential secondary structure forming sequences near the conserved branchpoint sequence. Nucleic Acids Res 16:10413-10423.
    • (1988) Nucleic Acids Res , vol.16 , pp. 10413-10423
    • Halfter, H.1    Gallwitz, D.2
  • 15
    • 0024221141 scopus 로고
    • Alternative splicing of tropomyosin pre-mRNAs in vitro and in vivo
    • Helfman DM, Ricci WM, Finn LA. 1988. Alternative splicing of tropomyosin pre-mRNAs in vitro and in vivo. Genes & Dev 2:1627-1638.
    • (1988) Genes & Dev , vol.2 , pp. 1627-1638
    • Helfman, D.M.1    Ricci, W.M.2    Finn, L.A.3
  • 16
    • 0025125897 scopus 로고
    • Identification of two distinct intron elements involved in alternative splicing of beta-tropomyosin pre-mRNA
    • Helfman DM, Roscigno RF, Mulligan GJ, Finn LA, Weber KS. 1990. Identification of two distinct intron elements involved in alternative splicing of beta-tropomyosin pre-mRNA. Genes & Dev 4:98-110.
    • (1990) Genes & Dev , vol.4 , pp. 98-110
    • Helfman, D.M.1    Roscigno, R.F.2    Mulligan, G.J.3    Finn, L.A.4    Weber, K.S.5
  • 17
    • 0031027009 scopus 로고    scopus 로고
    • A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor
    • Horowitz DS, Krainer AR. 1997. A human protein required for the second step of pre-mRNA splicing is functionally related to a yeast splicing factor. Genes & Dev 11:139-151.
    • (1997) Genes & Dev , vol.11 , pp. 139-151
    • Horowitz, D.S.1    Krainer, A.R.2
  • 18
    • 0002568139 scopus 로고    scopus 로고
    • A comparative view of initiation site selection
    • Hershey JWB, Mathews MB, Sonenberg N, eds. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press
    • Jackson RJ. 1996. A comparative view of initiation site selection. In: Hershey JWB, Mathews MB, Sonenberg N, eds. Translational Control. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory Press. pp 71-112.
    • (1996) Translational Control , pp. 71-112
    • Jackson, R.J.1
  • 19
    • 0026342613 scopus 로고
    • An analysis of verterbrate mRNA sequences: Intimations of translational control
    • Kozak M. 1991. An analysis of verterbrate mRNA sequences: Intimations of translational control. J Cell Biol 115:887-903.
    • (1991) J Cell Biol , vol.115 , pp. 887-903
    • Kozak, M.1
  • 20
    • 0027668951 scopus 로고
    • The spliceosome
    • Lamond AI. 1993. The spliceosome. BioEssays 15:595-603.
    • (1993) BioEssays , vol.15 , pp. 595-603
    • Lamond, A.I.1
  • 21
    • 0020531931 scopus 로고
    • Evidence for an intron contained sequence required for splicing of yeast RNA polymerase II transcripts
    • Langford CJ, Gallwitz D. 1981 Evidence for an intron contained sequence required for splicing of yeast RNA polymerase II transcripts. Cell 33:519-527.
    • (1981) Cell , vol.33 , pp. 519-527
    • Langford, C.J.1    Gallwitz, D.2
  • 22
    • 0029782402 scopus 로고    scopus 로고
    • The HeLa 200 kDa U5 snRNP-specific protein and its hornologue in Saccharomyces cerevisiae are members of the DEXH-box family of putative RNA helicases
    • Lauber J, Fabrizio P, Teigelkamp S, Lane WS, Hartmann E, Lührmann R. 1996. The HeLa 200 kDa U5 snRNP-specific protein and its hornologue in Saccharomyces cerevisiae are members of the DEXH-box family of putative RNA helicases. EMBO J 15:4001-4015.
    • (1996) EMBO J , vol.15 , pp. 4001-4015
    • Lauber, J.1    Fabrizio, P.2    Teigelkamp, S.3    Lane, W.S.4    Hartmann, E.5    Lührmann, R.6
  • 23
    • 0025026287 scopus 로고
    • Exon as well as intron sequences are cis-regulating elements for the mutually exclusive alternative splicing of the beta tropomyosin gene
    • Libri D, Goux Pelletan M, Brody E, Fiszman MY. 1990. Exon as well as intron sequences are cis-regulating elements for the mutually exclusive alternative splicing of the beta tropomyosin gene. Mol Cell Biol 10:5036-5046.
    • (1990) Mol Cell Biol , vol.10 , pp. 5036-5046
    • Libri, D.1    Goux Pelletan, M.2    Brody, E.3    Fiszman, M.Y.4
  • 24
    • 0029608909 scopus 로고
    • Ribosomal-proteins and elongation factors
    • Liljas A, Garber M. 1995. Ribosomal-proteins and elongation factors. Curr Opin Struct Biol 5:721-727.
    • (1995) Curr Opin Struct Biol , vol.5 , pp. 721-727
    • Liljas, A.1    Garber, M.2
  • 25
    • 0029016155 scopus 로고
    • A mammalian activity required for the second step of pre-messenger RNA splicing
    • Lindsey LA, Crow AJ, Garcia Blanco MA. 1995. A mammalian activity required for the second step of pre-messenger RNA splicing. J Biol Chem 270:13415-13421.
    • (1995) J Biol Chem , vol.270 , pp. 13415-13421
    • Lindsey, L.A.1    Crow, A.J.2    Garcia Blanco, M.A.3
  • 26
    • 0029944947 scopus 로고    scopus 로고
    • Detection of double-stranded RNA-protein interactions by methylene blue-mediated photo-crosslinking
    • Liu ZR, Wilkie AM, Clemens MJ, Smith CWJ. 1996. Detection of double-stranded RNA-protein interactions by methylene blue-mediated photo-crosslinking. RNA 2:611-621.
    • (1996) RNA , vol.2 , pp. 611-621
    • Liu, Z.R.1    Wilkie, A.M.2    Clemens, M.J.3    Smith, C.W.J.4
  • 27
    • 1842330298 scopus 로고    scopus 로고
    • The role of branchpoint-3′ splice site spacing and interaction betwen intron terminal nucleotides in 3′ splice site selection in Saccharomyces cerevisiae
    • Luukkonsen BGM, Seraphin B. 1997. The role of branchpoint-3′ splice site spacing and interaction betwen intron terminal nucleotides in 3′ splice site selection in Saccharomyces cerevisiae. EMBO J 16:779-792.
    • (1997) EMBO J , vol.16 , pp. 779-792
    • Luukkonsen, B.G.M.1    Seraphin, B.2
  • 28
    • 0028556367 scopus 로고
    • Dynamic RNA-RNA interactions in the spliceosome
    • Madhani HD, Guthrie C. 1994. Dynamic RNA-RNA interactions in the spliceosome. Annu Rev. Genet 28:1-26.
    • (1994) Annu Rev. Genet , vol.28 , pp. 1-26
    • Madhani, H.D.1    Guthrie, C.2
  • 29
    • 0026731973 scopus 로고
    • Ser/Thr-specific protein phosphates are required for both catalytic steps of pre-mRNA splicing
    • Mermoud JE, Cohen P, Lamond AI. 1992. Ser/Thr-specific protein phosphates are required for both catalytic steps of pre-mRNA splicing. Nucleic Acids Res 20:5263-5269.
    • (1992) Nucleic Acids Res , vol.20 , pp. 5263-5269
    • Mermoud, J.E.1    Cohen, P.2    Lamond, A.I.3
  • 30
    • 0028043718 scopus 로고
    • Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism
    • Mermound JE, Cohen PT, Lamond AI. 1994. Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism. EMBO J 13:5679-5688.
    • (1994) EMBO J , vol.13 , pp. 5679-5688
    • Mermound, J.E.1    Cohen, P.T.2    Lamond, A.I.3
  • 31
    • 0001877802 scopus 로고
    • Splicing of precursors to mRNA in the splicesome
    • Gesteland RF, Atkins JF, eds. Cold Spring Harbor, New York. Cold Spring Harbor Laboratory Press
    • Moore MJ, Query CC, Sharp PA. 1993. Splicing of precursors to mRNA in the splicesome. In: Gesteland RF, Atkins JF, eds. The RNA world. Cold Spring Harbor, New York. Cold Spring Harbor Laboratory Press. pp 303-358.
    • (1993) The RNA World , pp. 303-358
    • Moore, M.J.1    Query, C.C.2    Sharp, P.A.3
  • 32
    • 0027364421 scopus 로고
    • Evidence for two active sites in the spliceosome provided by sterochemistry of pre-mRNA splicing
    • Moore MJ, Sharp PA. 1993. Evidence for two active sites in the spliceosome provided by sterochemistry of pre-mRNA splicing. Nature 365:364-368.
    • (1993) Nature , vol.365 , pp. 364-368
    • Moore, M.J.1    Sharp, P.A.2
  • 33
    • 0020050314 scopus 로고
    • A catalogue of splice junction sequences
    • Mount SM. 1982. A catalogue of splice junction sequences. Nucleic Acids Res 10:459-472.
    • (1982) Nucleic Acids Res , vol.10 , pp. 459-472
    • Mount, S.M.1
  • 34
    • 0025892442 scopus 로고
    • Alpha-tropomyosin mutually exclusive exon selection: Competition between branchpoint/polypyrimidine tracts determines default exon choice
    • Mullen MP, Smith CWJ, Patton JG, Nadal Ginard B. 1991. Alpha-tropomyosin mutually exclusive exon selection: Competition between branchpoint/polypyrimidine tracts determines default exon choice. Genes & Dev 5:642-655.
    • (1991) Genes & Dev , vol.5 , pp. 642-655
    • Mullen, M.P.1    Smith, C.W.J.2    Patton, J.G.3    Nadal Ginard, B.4
  • 35
    • 0026605043 scopus 로고
    • U5 snRNA interacts with exon sequenes at 5′ and 3′ splice sites
    • Newman AJ, Norman C. 1992. U5 snRNA interacts with exon sequenes at 5′ and 3′ splice sites. Cell 68:743-754.
    • (1992) Cell , vol.68 , pp. 743-754
    • Newman, A.J.1    Norman, C.2
  • 36
    • 0029400769 scopus 로고
    • snRNA interactions at 5′ and 3′ splice sites monitored by photoactivated crosslinking in yeast spliceosomes
    • Newman AJ, Teigelkamp S, Beggs JD. 1995. snRNA interactions at 5′ and 3′ splice sites monitored by photoactivated crosslinking in yeast spliceosomes. RNA 1:968-980.
    • (1995) RNA , vol.1 , pp. 968-980
    • Newman, A.J.1    Teigelkamp, S.2    Beggs, J.D.3
  • 37
    • 0028308696 scopus 로고
    • RNA-RNA interactions in the spliceosome; Unravelling the ties that bind
    • Nilsen T. 1994. RNA-RNA interactions in the spliceosome; Unravelling the ties that bind. Cell 78:1-4.
    • (1994) Cell , vol.78 , pp. 1-4
    • Nilsen, T.1
  • 38
    • 0029818631 scopus 로고    scopus 로고
    • Transcription processivity: Protein-DNA interactions holding together the elongation complex
    • Nudler E, Avetissova E, Markovtsov V, Glodfarb A. 1996. Transcription processivity: Protein-DNA interactions holding together the elongation complex. Science 273:211-217.
    • (1996) Science , vol.273 , pp. 211-217
    • Nudler, E.1    Avetissova, E.2    Markovtsov, V.3    Glodfarb, A.4
  • 39
    • 0030598839 scopus 로고    scopus 로고
    • The invariant U5 snRNA loop-1 sequence is dispensable for the first catalytic step of pre-mRNA splicing in yeast
    • O'Keefe RT, Norman C, Newman AJ. 1996. The invariant U5 snRNA loop-1 sequence is dispensable for the first catalytic step of pre-mRNA splicing in yeast. Cell 86:679-689.
    • (1996) Cell , vol.86 , pp. 679-689
    • O'Keefe, R.T.1    Norman, C.2    Newman, A.J.3
  • 40
    • 0027408848 scopus 로고
    • Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron
    • Parker R, Siliciano PG. 1993. Evidence for an essential non-Watson-Crick interaction between the first and last nucleotides of a nuclear pre-mRNA intron. Nature 361:660-662.
    • (1993) Nature , vol.361 , pp. 660-662
    • Parker, R.1    Siliciano, P.G.2
  • 41
    • 0026030643 scopus 로고
    • A U-rich tract enhances usage of an alternative 3′ splice site in yeast
    • Patterson B, Guthrie C. 1991. A U-rich tract enhances usage of an alternative 3′ splice site in yeast. Cell 64:181-187.
    • (1991) Cell , vol.64 , pp. 181-187
    • Patterson, B.1    Guthrie, C.2
  • 43
    • 0028205987 scopus 로고
    • Branch nucleophile selection in pre-mRNA splicing: Evidence for the bulged duplex model
    • Query CC, Moore MJ, Sharp PA. 1994. Branch nucleophile selection in pre-mRNA splicing: Evidence for the bulged duplex model. Genes & Dev 8:587-597.
    • (1994) Genes & Dev , vol.8 , pp. 587-597
    • Query, C.C.1    Moore, M.J.2    Sharp, P.A.3
  • 44
    • 0024808994 scopus 로고
    • The organization of 3′ splice-site sequence in mammalian introns
    • Reed R. 1989. The organization of 3′ splice-site sequence in mammalian introns. Genes & Dev 3:2113-2123.
    • (1989) Genes & Dev , vol.3 , pp. 2113-2123
    • Reed, R.1
  • 45
    • 0025096053 scopus 로고
    • Protein composition of mammalian spliceosomes assembled in vitro
    • Reed R. 1990. Protein composition of mammalian spliceosomes assembled in vitro. Proc Natl Acad Sci USA 87:8031-8035.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 8031-8035
    • Reed, R.1
  • 46
    • 0029933504 scopus 로고    scopus 로고
    • Initial splice-site recognition and pairing during premRNA splicing
    • Reed R. 1996. Initial splice-site recognition and pairing during premRNA splicing. Curr Opin Genet Dev 6:215-220.
    • (1996) Curr Opin Genet Dev , vol.6 , pp. 215-220
    • Reed, R.1
  • 47
    • 0021887989 scopus 로고
    • Intron sequences involved in lariat formation during pre-mRNA splicing
    • Reed R, Maniatis T. 1985. Intron sequences involved in lariat formation during pre-mRNA splicing. Cell 41:95-105.
    • (1985) Cell , vol.41 , pp. 95-105
    • Reed, R.1    Maniatis, T.2
  • 48
    • 0026624840 scopus 로고
    • Mutations at the 3′ splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast
    • Reich CI, VanHoy RW, Porter GL, Wise JA. 1992. Mutations at the 3′ splice site can be suppressed by compensatory base changes in U1 snRNA in fission yeast. Cell 69:1159-1169.
    • (1992) Cell , vol.69 , pp. 1159-1169
    • Reich, C.I.1    VanHoy, R.W.2    Porter, G.L.3    Wise, J.A.4
  • 49
    • 0031028688 scopus 로고    scopus 로고
    • Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome
    • Rodina MV, Savelsbergh A, Katunin VI, Wintermeyer W. 1997. Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature 385:37-41.
    • (1997) Nature , vol.385 , pp. 37-41
    • Rodina, M.V.1    Savelsbergh, A.2    Katunin, V.I.3    Wintermeyer, W.4
  • 50
    • 0025176473 scopus 로고
    • Bidirectional RNA helicase activity of eukaryotic translation initiation factor-4A and factor 4-F
    • Rozen F, Edery I, Meerovitch K, Dever TE, Merrick WC, Sonenberg N. 1990. Bidirectional RNA helicase activity of eukaryotic translation initiation factor-4A and factor 4-F. Mol Cell Biol 10:1134-1144.
    • (1990) Mol Cell Biol , vol.10 , pp. 1134-1144
    • Rozen, F.1    Edery, I.2    Meerovitch, K.3    Dever, T.E.4    Merrick, W.C.5    Sonenberg, N.6
  • 51
    • 0028646169 scopus 로고
    • The interaction between the first and last intron nucleotides in the second step of pre-mRNA splicing is independent of other conserved intron nucleotides
    • Ruis BL, Kivens WJ, Siliciano PG. 1994. The interaction between the first and last intron nucleotides in the second step of pre-mRNA splicing is independent of other conserved intron nucleotides. Nucleic Acids Res 22:5190-5195.
    • (1994) Nucleic Acids Res , vol.22 , pp. 5190-5195
    • Ruis, B.L.1    Kivens, W.J.2    Siliciano, P.G.3
  • 52
    • 0022380943 scopus 로고
    • Role of the 3′ splice site consensus sequence in mammalian pre-mRNA splicing
    • Ruskin B, Green MR. 1985. Role of the 3′ splice site consensus sequence in mammalian pre-mRNA splicing. Nature 317:732-734.
    • (1985) Nature , vol.317 , pp. 732-734
    • Ruskin, B.1    Green, M.R.2
  • 53
    • 0025742772 scopus 로고
    • Alterations of RNase H sensitivity of the 3′ splice site region during the in vitro splicing reaction
    • Sawa H, Shimura Y. 1991. Alterations of RNase H sensitivity of the 3′ splice site region during the in vitro splicing reaction. Nucleic Acids Res 19:3953-3958.
    • (1991) Nucleic Acids Res , vol.19 , pp. 3953-3958
    • Sawa, H.1    Shimura, Y.2
  • 54
    • 0029069220 scopus 로고
    • Interactions betwen the terminal bases of mammalian introns are retained in inosine-containing pre-mRNAs
    • Scadden ADJ, Smith CWJ. 1995. Interactions betwen the terminal bases of mammalian introns are retained in inosine-containing pre-mRNAs. EMBO J 14:3236-3246.
    • (1995) EMBO J , vol.14 , pp. 3236-3246
    • Scadden, A.D.J.1    Smith, C.W.J.2
  • 55
    • 0022814974 scopus 로고
    • Two functional alpha-tubulin genes of the yeast saccharomyces cerevisiae encode divergent proteins
    • Schatz PJLP, Grisafi P, Solomon F, Botstein D. 1986. Two functional alpha-tubulin genes of the yeast saccharomyces cerevisiae encode divergent proteins. Mol Cell Biol 6:3711-3721.
    • (1986) Mol Cell Biol , vol.6 , pp. 3711-3721
    • Schatz, P.J.L.P.1    Grisafi, P.2    Solomon, F.3    Botstein, D.4
  • 56
    • 0026019713 scopus 로고
    • PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome
    • Schwer B, Guthrie C. 1991. PRP16 is an RNA-dependent ATPase that interacts transiently with the spliceosome. Nature 349:494-499.
    • (1991) Nature , vol.349 , pp. 494-499
    • Schwer, B.1    Guthrie, C.2
  • 57
    • 0027065506 scopus 로고
    • A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis
    • Schwer B, Guthrie C. 1992. A conformational rearrangement in the spliceosome is dependent on PRP16 and ATP hydrolysis. EMBO J 11:5033-5039.
    • (1992) EMBO J , vol.11 , pp. 5033-5039
    • Schwer, B.1    Guthrie, C.2
  • 58
    • 0028307171 scopus 로고
    • Split genes and RNA splicing
    • Sharp PA. 1994. Split genes and RNA splicing. Cell 77:805-15.
    • (1994) Cell , vol.77 , pp. 805-815
    • Sharp, P.A.1
  • 59
    • 0027214101 scopus 로고
    • Scanning and competition between AGs are involved in 3′ splice site selection in mammalian introns
    • Smith CWJ, Chu TT, Nadal Ginard B. 1993. Scanning and competition between AGs are involved in 3′ splice site selection in mammalian introns. Mol Cell Biol 13:4939-4952.
    • (1993) Mol Cell Biol , vol.13 , pp. 4939-4952
    • Smith, C.W.J.1    Chu, T.T.2    Nadal Ginard, B.3
  • 60
    • 0024594710 scopus 로고
    • Mutually exclusive splicing of alpha-tropomyosin exons enforced by an unusual lariat branch point location: Implications for constitutive splicing
    • Smith CWJ, Nadal Ginard B. 1989. Mutually exclusive splicing of alpha-tropomyosin exons enforced by an unusual lariat branch point location: Implications for constitutive splicing. Cell 56:749-758.
    • (1989) Cell , vol.56 , pp. 749-758
    • Smith, C.W.J.1    Nadal Ginard, B.2
  • 61
    • 0024470631 scopus 로고
    • Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns
    • Smith CWJ, Porro EB, Patton JG, Nadal Ginard B. 1989. Scanning from an independently specified branch point defines the 3′ splice site of mammalian introns. Nature 342:243-247.
    • (1989) Nature , vol.342 , pp. 243-247
    • Smith, C.W.J.1    Porro, E.B.2    Patton, J.G.3    Nadal Ginard, B.4
  • 62
    • 0027739853 scopus 로고
    • The U5 and U6 small nuclear RNAs as active site components of the spliceosome
    • Sontheimer EJ, Steitz JA. 1993. The U5 and U6 small nuclear RNAs as active site components of the spliceosome. Science 262:1989-1996.
    • (1993) Science , vol.262 , pp. 1989-1996
    • Sontheimer, E.J.1    Steitz, J.A.2
  • 63
    • 0029031713 scopus 로고
    • Extensive interactions of PRP8 protein with the 5′ and 3′ splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA
    • Tetgelkamp S, Newman AJ, Beggs JD. 1995. Extensive interactions of PRP8 protein with the 5′ and 3′ splice sites during splicing suggest a role in stabilization of exon alignment by U5 snRNA. EMBO J 14:2602-2612.
    • (1995) EMBO J , vol.14 , pp. 2602-2612
    • Tetgelkamp, S.1    Newman, A.J.2    Beggs, J.D.3
  • 64
    • 0029397324 scopus 로고
    • The second catalytic step of pre-mRNA splicing
    • Umen JG, Guthrie C. 1995. The second catalytic step of pre-mRNA splicing RNA 1:869-885.
    • (1995) RNA , vol.1 , pp. 869-885
    • Umen, J.G.1    Guthrie, C.2
  • 65
    • 0027651150 scopus 로고
    • Protein-composition of mammalian spliceosomal snRNPs
    • Will CL, Behrens SE, Lührmann R. 1993. Protein-composition of mammalian spliceosomal snRNPs. Mol Biol Reports 18:121-126.
    • (1993) Mol Biol Reports , vol.18 , pp. 121-126
    • Will, C.L.1    Behrens, S.E.2    Lührmann, R.3
  • 66
    • 0343907206 scopus 로고    scopus 로고
    • Protein functions in pre-mRNA splicing
    • Will CL, Luhrmann R. 1997. Protein functions in pre-mRNA splicing. Curr Opin Cell Biol 9:320-328.
    • (1997) Curr Opin Cell Biol , vol.9 , pp. 320-328
    • Will, C.L.1    Luhrmann, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.