Interruption of g protein-coupling in CXCR2 does not alter ligand binding, but eliminates ligand-activation of GTPγ35S binding, calcium mobilization, and chemotaxis

Biochemistry

Volumn 36, Issue 49, 1997, Pages 15193-15200

  Yang, Wei ^a   Schraw, Wayne P ^a   Mueller, Susan G ^a   Richmond, Ann ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ASPARAGINE; GUANINE NUCLEOTIDE BINDING PROTEIN; INTERLEUKIN 8;

ARTICLE; BINDING AFFINITY; CALCIUM MOBILIZATION; CHEMOTAXIS; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN BINDING; SIGNAL TRANSDUCTION;

CALCIUM; CELL LINE; CHEMOKINES, CXC; CHEMOTACTIC FACTORS; CHEMOTAXIS; ENDOCYTOSIS; GROWTH SUBSTANCES; GTP-BINDING PROTEINS; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIGANDS; MUTATION; PROTEIN BINDING; RECEPTORS, CHEMOKINE; RECEPTORS, INTERLEUKIN; RECEPTORS, INTERLEUKIN-8B; SULFUR RADIOISOTOPES;

EID: 0030669016     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi971594u     Document Type: Article

References (40)

1. Baggiolini, M., Dewald, B., and Moser, B. (1994) Adv. Immunol. 55, 97.
2. Baggiolini, M., Loetscher, P., and Moser, B. (1995) Int. J. Immunopharmacol. 17, 103.
3. Oppenheim, J. J., Zachariae, C. O., Mukaida, N., and Matsushima, K. (1991) Annu. Rev. Immunol. 9, 617.
4. Murphy, P. M., and Tiffany, H. L. (1991) Science 253, 1280.
5. Cesarman, E., Bai, F., Bohenzky, R. A., Russo, J. J., Moore, P. S., Chang, Y., and Knowles, D. M. (1996) J. Virol. 70, 8218.
6. Holmes, W. E., Lee, J., Kuang, W. J., Rice, G., and Wood, W. I. (1991) Science 253, 1278.
7. Wu, D., LaRosa, G. J., and Simon, M. I. (1993) Science 261, 101.
8. Mueller, S., White, J. R., Schraw, W. P., Lam, Vinh., and Richmond, A. (1997) J. Biol. Chem. 272, 8207.
9. Damaj, B. B., McColl, S. R., Mahana, W., Crouch, M. F., and Naccache, P. H. (1996) J. Biol. Chem. 271, 12783.
10. Hawes, B. E., Luttrell, L. M., Exum, S. T., and Lefkowitz, R. J. (1994) J. Biol. Chem. 269, 15776.
11. Moro, O., Lameh, J., Hogger, P., and Sadee, W. (1993) J. Biol. Chem. 268, 22273.
12. O'Dowd, B. F., Hnatowich, M., Regan, J. W., Leader, W. M., Caron, M. G., and Lefkowitz, R. J. (1988) J. Biol. Chem. 263, 15985.
13. Arora, K. K., Sakai, A., and Catt, K. J. (1995) J. Biol. Chem. 270, 22820.
14. Hogger, P., Shockley, M. S., Lameh, J., and Sadee, W. (1995) J. Biol. Chem 270, 7405.
15. Damaj, B. B., McColl, S. R., Neote, K., Songqing, N., Ogborn, K. T., Hebert, C. A., and Naccache, P. H. (1996) FASEB J. 10, 1426.
16. Okamoto, T., and Nishimoto, I. (1992) J. Biol. Chem. 267, 8342.
17. Mueller, S. G., Schraw, W. P., and Richmond, A. (1994) J. Biol. Chem. 269, 1973.
18. Rosenthal, A., Lindquist, P. B., Bringman, T. S., Goeddel, D. V., and Derynck, R. (1986) Cell 46, 301.
19. Haigler, H. T., Maxfield, F. R., Willingham, M. C., and Pastan, I. (1980) J. Biol. Chem. 255, 1239.
20. Kupper, R. W., Dewald, B., Jakobs, K. H., Baggiolini, M., and Gierschik, P. (1992) Biochem. J. 282, 429.
21. Ben-Baruch, A., Bengali, K. M., Biragyn, A., Johnston J. J., Wang, J. M., Kim, J., Chuntharapai, A., Michiel, D. F., Oppenheim, J. J., and Kelvin, D. J. (1995) J. Biol. Chem. 270, 9121.
22. Ji, I., and Ji, T. H. (1991) J. Biol. Chem. 266, 14953.
23. Horstman, D. A., Brandon, S., Wilson, A. L., Guyer, C. A., Cragoe, E. J., Jr., and Limbird, L. E. (1990) J. Biol. Chem. 265, 21590.
24. Bihoreau, C., Monnot, C., Davies, E., Teutsch, B., Bernstein, K. E. Corvol, P., and Clauser, E. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 5133.
25. Henderson, R., Baldwin, J. M., Ceska, T. A. Zemlin, F., Beckmann, E., and Downing, K. H. ( 1990) J. Mol. Biol. 213, 899.
26. Schertler, G. F., Villa, C., and Henderson, R. (1993) Nature 362, 770.
27. Wong, S. K., Parker, E. M., and Ross, E. M. (1990) J. Biol. Chem. 265, 6219.
28. Kunkel, M. T., and Peralta, E. G. (1993) EMBO J. 12, 3809.
29. Shapiro, R. A., Palmer, D., and Cislo, T. (1993) J. Biol. Chem. 268, 21734.
30. Wade, S. M., Scribner, M. K., Dalman, H. M., Taylor, J. M., Neubig, R. R. (1996) Mol. Pharmacol. 50, 351.
31. Okamoto, T., Katada, T., Murayama, Y., Ui, M., Ogata, E., and Nishimoto, I. (1990) Cell 62, 709.
32. Cheung, A. H., Huang, R. R., and Strader, C. D. (1992) Mol. Pharmacol. 41, 1061.
33. Voss, T., Wallner, E., Czernilofsky, A. P., and Freissmuth, M. (1993) J. Biol. Chem. 268, 4637.
34. Prossnitz, E. R., Schreiber, R. E., Bokoch, G. M., and Ye, K. D. (1995) J. Biol. Chem. 270, 10686.
35. Dalman, H. M., and Neubig, R. R. (1991) J. Biol. Chem. 266, 11025.
36. Kjelsberg, M. A., Cotecchia, S., Ostrowski, J., Caron, M. G., and Lefkowitz, R. J. (1992) J. Biol. Chem. 267, 1430.
37. Zastrow, V., and Kobilka, B. K. (1992) J. Biol. Chem. 267, 3530.
38. Yu, S. S., Lefkowitz, R. J., and Hausdorff, W. P. (1993) J. Biol. Chem. 268, 337.
39. Lameh, J., Phillip, M., Sharma, Y. K., Moro, O., Ramachandran, J., and Sadee, W. (1992) J. Biol. Chem. 267, 13406.
40. Bock, B., Martin, U., Gâter, S., Rheinheimer, C., Raffetseder, U., Arseniev, L., Barker, M. D., Monk, P. N., Bautsch, W., Köhl, J., and Klos, A. (1997) Eur. J. Immunol. 27, 1552.