Human leukemia-derived dendritic cells: Ex-vivo development of specific antileukemic cytotoxicity

Critical Reviews in Immunology

Volumn 18, Issue 1-2, 1997, Pages 121-131

  Choudhury, Aniruddha ^a   Toubert, Antoine ^b   Sutaria, Sapna ^a   Charron, Dominique ^b   Champlin, Richard E ^a   Claxton, David F ^c  

^a UNIVERSITY OF TEXAS   (United States)

^b SAINT LOUIS HOSPITAL   (France)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Antigen presentation; Dendritic cells; Fas; Immunotherapy; Leukemia; T cell immunity

Indexed keywords

CD8 ANTIGEN; HLA ANTIGEN; TUMOR ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR;

ADOPTIVE IMMUNOTHERAPY; ANTIGEN RECOGNITION; ANTIGEN SPECIFICITY; BONE MARROW CELL; CANCER CELL CULTURE; CANCER IMMUNOTHERAPY; CELL CLONE; CHRONIC MYELOID LEUKEMIA; CONFERENCE PAPER; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; ARTICLE; CYTOTOXICITY TEST; IMMUNOLOGY; MYELOID LEUKEMIA; MYELOMONOCYTIC LEUKEMIA; PHILADELPHIA 1 CHROMOSOME;

CYTOTOXICITY TESTS, IMMUNOLOGIC; DENDRITIC CELLS; HUMANS; LEUKEMIA, MYELOID; LEUKEMIA, MYELOID, CHRONIC; LEUKEMIA, MYELOMONOCYTIC, ACUTE; PHILADELPHIA CHROMOSOME; RECEPTORS, ANTIGEN, T-CELL;

EID: 0030663918     PISSN: 10408401     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (31)

1. Claxton, D. F., Deisseroth, A., Talpaz, M., Reading, C., Kantarjian, H., Trujillo, J., Stass, S., Gooch, G., and Sptizer, G., Polyclonal hematopoiesis in interferon-induced cytogenetic remissions of chronic myelogenous leukemia, Blood, 79, 997, 1992.
2. Clift, R. A., Appelbaum, F. R., and Thomas, E. D., Treatment of chronic myeloid leukemia by marrow T transplantation, Blood, 82, 1954, 1993.
3. Kolb, H. J., Schattenberg, A., Goldman, J. M., Hertenstein, B., Jacobsen, N., Arcese, W., Ljungman, P., Ferrant, A., Verdonck, L., Niederwieser, D., Van Rhee, F., Mittermueller, J., De Witte, T., Holler, E., and Ansari, H., Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients, Blood, 86, 2041, 1995.
4. Giralt, S., Hester, J., Hun, Y., Hirsh-Ginsberg, C., Rondon, G., Seong, D., Lee, M., Gajewski, J., Van Besien, K., Khouri, I., Mehra, R., Prezepiorka, D., Korbling, M., Talpaz, M., Kantarjian, H. M., Fischer, G., Deisseroth, A., and Champlin, R., CD8-depleted donor lymphocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic Bone marrow transplantation, Blood, 86, 4337, 1995.
5. + T lymphocytes can exert cytotoxicity to chronic myeloid leukaemia cells processing and presenting exogenous antigen, Br. J. Haematol., 93, 606, 1996.
6. Meloni, G., Foa, R., Vignetti, M., Guarini, A., Fenu, S., Tosti, S., Grillo Tos, A., and Mandelli, F., IL-2 may induce prolonged remissions in advanced AML, Blood, 84, 2158, 1994.
7. Mackinnon, S., Hows, J., and Goldman, J., Induction of in vitro graft-versus-leukemia activity following bone marrow transplantation for CML, Blood, 76, 2037, 1990.
8. Cervantes, F., Pierson, B., McGlave, P., Verfaillie, C., and Miller, J., Autologous activated natural killer cells suppress primitive CML progenitors in long-term culture, Blood, 87, 2476, 1996.
9. Soiffer, R. J., Murray, C., Gonin, R., and Ritz, J., Effect of low-dose IL-2 on disease relapse after T-cell depleted allogeneic bone marrow transplantation, Blood, 84, 964, 1994.
10. Coleman, S., Fisher, J., Hoy, T., Burnett, A. K., and Lim, S. H., Autologous MHC-dependent leukemia-reactive T lymphocytes in a patient with CML, Leukemia, 10, 483, 1996.
11. Talpaz, M., Kantarjian, H. M., McCredie, K., Trujillo, J. M., Keating, M. J., and Gutterman, J. U., Hematologic remission and cytogenetic improvement induced by recombinant human interferon alpha A in chrome myelogenous leukemia, N. Engl. J. Med., 314, 1065, 1986.
12. Cheever, M. A., Chen, W., Disis, M. L., Takahashi, M., and Peace, D. J., T-cell immunity to oncogenic proteins including mutated ras and chimeric bcr-abl. (Review), Ann. New York Acad. Sci., 690, 101, 1993.
13. Pawelec, G., Max, H., Halder, T., Bruserud, O., Merl, A., Da Silva, P., and Kalbacher, H., BCR/ ABL leukemia oncogene fusion peptides selectively bind to certain HLA-DR alleles and can be recognized by T cells found at low frequency in the repertoire of normal donors, Blood, 88, 2118, 1996.
14. Cullis, J. O., Barrett, A. J., Goldman, J. M., and Lechler, R. I., Binding of BCR/ABL junctional peptides to major histocompatibility complex (MHC) class I molecules: studies in antigen-processing defective cell lines, Leukemia, 8, 165, 1994.
15. Bocchia, M., Korontsvit, T., Xu, Q., Mackinnon, S., Yang, S. Y., Sette, A., and Scheinberg, D. A., Specific human cellular immunity to bcr-abl oncogene-derived peptides, Blood, 87, 3587, 1996.
16. Tilkin, A. F., Lubin, R., Soussi, T., Lazar, V., Janin, N., and Mathieu, M. C., Primary proliferative T-Cell responses to wild type p53 protein in patients with breast cancer, Eur. J. Immunol., 25, 1765, 1995.
17. Molldrem, J., Dermime, S., Parker, K., Mavroudis, D., Jiang, Y. Z., Hensel, N., and Barrett, A. J., Cytotoxic T lymphocytes specific for a MHC class I-restricted peptide derived from the leukemia-associated protein proteinase 3 also show specificity toward fresh leukemic cells (Meeting abstract), Proc. Annu. Meet. Am. Soc. Clin. Oncol., 15, A1059, 1996.
18. Choudhury, A., Gajewski, J. L., Liang, J. C., Popat, U., Claxton, D. F., Kliehe, K., Andreeff, M., and Champlin, R. E., Use of leukemic dendritic cells for the generation of antileukemic cellular cytotoxicity against Philadelphia chromosome-positive chronic myelogenous leukemia, Blood, 44, 1133, 1996.
19. Selleri, C., Sato, T., Vecchio, L. D., Barrett, A. J., Rotoli, B., Young, N. S., and Maciejewski, J. P., Involvement of fas-mediated apoptosis in the inhibitory effects of interferon-a in chronic myelogenous leukemia, Blood, 89, 957, 1997.
20. Pannatier, C., Even, J., and Kourilsky, P., T-cell repertoire diversity and clonal expansions in normal and clinical samples, Immunology, 16, 176, 1995.
21. Lim, A., Toubert, A., Pannetier, C., Dougados, M., Charron, D., Kourilsky, P., and Even, J., Spread of clonal T-cell expansions in rheumatoid arthritis patients, Hum. Immunol., 48, 77, 1996.
22. Caignard, A., Dietrich, P., Morand, V., Lim, A., Pannatier, C., Leridant, A., Hercend, T., Even, J., Kourilsky, P., and Triebel, F., Evidence for T-cell clonal expansion in a patient with squamous cell carcinoma of the head and neck, Cancer Res, 54, 1292, 1994.
23. Puisieux, I., Bain, C., Merrouche, Y., Malacher, P., Kourilsky, P., Even, J., and Favrot, M., Restriction of the T-cell reperoire in tumor infiltrating lymphocytes from nine patients with renal cell carcinoma. Relevance of the CDR3 lenght analysis for the iden- tification of in situ clonal T-cell expansions, Int. J. Canc., 66, 201, 1996.
24. Santiago-Schwarz, F., Coppock, D. L., Hindenburg, A. A., and Kern, J., Identification of a malignant counterpart of the monocyte-dendritic cell progenitor in an acute myeloid leukemia, Blood, 84, 3054, 1994.
25. Boyer, M. W., Johnson, T. S., Waller, E. K., and Yeager, A. M., Cytokine upregulation of acute myeloid leukemia costimulatory function, Blood, 88, 1996.
26. Robinson, S. P., Kearney, L., Jalo, R. J., Knight, S. C., Reid, C. D. L., and Samson, D., Proof of malignant clone of origin of dendritic cells growing in culture from a patient with del(5)(q13q33) acute mixed lineage leukemia, Blood, 88, 1996.
27. Terstappen, L. W. M. M., Safford, M., Unterhalt, M., Könemann, S., Zurlutter, K., Piechotka, K., Drescher, M., Aul, C., Büchner, T., Hiddemann, W., and Wörmann, B., Flow cytometric characterization of acute myeloid leukemia: IV. Comparison to the differentiation pathway of normal hematopoietic progenitor cells, Leukemia, 6, 993, 1992.
28. Claxton, D. F. and Albitar, M., Acute leukemias: phenotyping and genotyping, Leukemia, 9, 2150, 1995.
29. Ridge, J. P., Fuchs, E. J., and Matzinger, P., Neonatal tolerance revisited: turning on newborn T cells with dendritic cells, Science, 271, 1723-1726, 1996.
30. Nelson, E. L., Li, X., Hsu, F. J., Kwak, L., Levy, R., Clayberger, C., and Krensky, A. M., Tumor-specific, cytotoxic T-lymphocyte response after idiotype vaccination for B-cell, non-Hodgkin's lumphoma, Blood, 88, 580, 1996.
31. + T cells elicited by primary in vitro immunization with a BCR-ABL breakpoint peptide, Blood, 88, 3522, 1996.