-
1
-
-
0022479537
-
Folinic acid augmentation of the effects of fluoropyrimidines on murine and human leukemic cells
-
Keyomarsi K, Moran RG: Folinic acid augmentation of the effects of fluoropyrimidines on murine and human leukemic cells. Cancer Res 46:5229-5235, 1986
-
(1986)
Cancer Res
, vol.46
, pp. 5229-5235
-
-
Keyomarsi, K.1
Moran, R.G.2
-
2
-
-
0023485117
-
Biochemical and pharmacologic basis for potentiation of 5-fluorouracil action by leucovorin
-
Rustum YM, Trave F, Zakrzewski SF, et al: Biochemical and pharmacologic basis for potentiation of 5-fluorouracil action by leucovorin. NCI Monosr 5:165-170, 1987
-
(1987)
NCI Monosr
, vol.5
, pp. 165-170
-
-
Rustum, Y.M.1
Trave, F.2
Zakrzewski, S.F.3
-
3
-
-
0022970777
-
The effect of methotrexate on intracellular folate pools in human MCF-y breast cancer cells: Evidence for direct inhibition of purine synthesis
-
Allegra CJ, Fine RL, Drake JC, et al: The effect of methotrexate on intracellular folate pools in human MCF-y breast cancer cells: Evidence for direct inhibition of purine synthesis. J Biol Chem 261:6478-6485, 1986
-
(1986)
J Biol Chem
, vol.261
, pp. 6478-6485
-
-
Allegra, C.J.1
Fine, R.L.2
Drake, J.C.3
-
4
-
-
0019349301
-
Biochemical determinants of responsiveness to 5-fluorouracil and derivatives in xenografts of human colorectal adenocarcinoma in mice
-
Houghton JA, Maroda SJ, Phillips JO, et al: Biochemical determinants of responsiveness to 5-fluorouracil and derivatives in xenografts of human colorectal adenocarcinoma in mice. Cancer Res 41-144-149, 1981
-
(1981)
Cancer Res
-
-
Houghton, J.A.1
Maroda, S.J.2
Phillips, J.O.3
-
5
-
-
0019415841
-
Effects of excess and deoxyinosine on the activity and site of action of 5-fluorouracil
-
Evans RM, Laskin JD, Hakala MT: Effects of excess and deoxyinosine on the activity and site of action of 5-fluorouracil. Cancer Res 41:3288-3295, 1981
-
(1981)
Cancer Res
, vol.41
, pp. 3288-3295
-
-
Evans, R.M.1
Laskin, J.D.2
Hakala, M.T.3
-
6
-
-
0023874456
-
A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal cancer
-
Erlichman C, Fine S, Wong A, et al: A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal cancer. J Clin Oncol 6:469-475, 1988
-
(1988)
J Clin Oncol
, vol.6
, pp. 469-475
-
-
Erlichman, C.1
Fine, S.2
Wong, A.3
-
7
-
-
0023520170
-
A prospective randomized trial of 5-fluorouracil vs. 5-fluorouracil and high dose leucovorin + 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma
-
Petrelli N, Herrera L, Rustum Y, et al: A prospective randomized trial of 5-fluorouracil vs. 5-fluorouracil and high dose leucovorin + 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma. J Clin Oncol 5:1559-1565, 1987
-
(1987)
J Clin Oncol
, vol.5
, pp. 1559-1565
-
-
Petrelli, N.1
Herrera, L.2
Rustum, Y.3
-
8
-
-
0024342059
-
Treatment of patients with advanced colorectal carcinomas with fluorouracil alone, hioh-dose leucovorin plus fluorouracil, or sequential methotrexate, fluorouracil, and leucovorin: A randomized trial of the Northern California Oncology Group
-
Valone FH, Freidman MA, Wittlinger PS, et al: Treatment of patients with advanced colorectal carcinomas with fluorouracil alone, hioh-dose leucovorin plus fluorouracil, or sequential methotrexate, fluorouracil, and leucovorin: A randomized trial of the Northern California Oncology Group. J Clin Oncol 7:1419-1426
-
J Clin Oncol
, vol.7
, pp. 1419-1426
-
-
Valone, F.H.1
Freidman, M.A.2
Wittlinger, P.S.3
-
9
-
-
0025261244
-
Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy
-
Doroshaw JH, Bertrand M, Multhauf P, et al: Prospective randomized comparison of fluorouracil versus fluorouracil and high-dose continuous infusion leucovorin calcium for the treatment of advanced measurable colorectal cancer in patients previously unexposed to chemotherapy. J Clin Oncol 8:491-501, 1990
-
(1990)
J Clin Oncol
, vol.8
, pp. 491-501
-
-
Doroshaw, J.H.1
Bertrand, M.2
Multhauf, P.3
-
10
-
-
0024385167
-
The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: A prospective randomized phase III trial
-
Petrelli N, Douglass HO, Herrera L, et al: The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: A prospective randomized phase III trial. J Clin Oncol 7:1419-1426, 1989
-
(1989)
J Clin Oncol
, vol.7
, pp. 1419-1426
-
-
Petrelli, N.1
Douglass, H.O.2
Herrera, L.3
-
11
-
-
0026006962
-
Biochemical modulation of fluorouracil with leucovorin: Confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer
-
Poon MA, O'Connell MJ, Wieand HS, et al: Biochemical modulation of fluorouracil with leucovorin: Confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer. J Clin Oncol 9:1967-1972, 1991
-
(1991)
J Clin Oncol
, vol.9
, pp. 1967-1972
-
-
Poon, M.A.1
O'Connell, M.J.2
Wieand, H.S.3
-
12
-
-
0026721532
-
The Advanced Colorectal Cancer Meta-Analysis Project: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
-
Anonymous: The Advanced Colorectal Cancer Meta-Analysis Project: Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate. J Clin Oncol 10:896-903, 1992
-
(1992)
J Clin Oncol
, vol.10
, pp. 896-903
-
-
-
13
-
-
0022504403
-
Preparation of (6R)-tetrahydrofolic acid and (6S)-5-formyltetrahydrofolic acid of high stereo chemical purity
-
Sato JK, Newman EM, Moran RG: Preparation of (6R)-tetrahydrofolic acid and (6S)-5-formyltetrahydrofolic acid of high stereo chemical purity. Anal Biochem 154:516-524, 1986
-
(1986)
Anal Biochem
, vol.154
, pp. 516-524
-
-
Sato, J.K.1
Newman, E.M.2
Moran, R.G.3
-
14
-
-
0018690601
-
Stereo specificity at carbon 6 of formyl tetrahydrofolate as a competitive inhibitor of transport and cytotoxicity of methotrexate in vitro
-
Sirotnak FM, Chello PL, Moccio DM, et al: Stereo specificity at carbon 6 of formyl tetrahydrofolate as a competitive inhibitor of transport and cytotoxicity of methotrexate in vitro. Biochem Pharmacol 28:2993-2997, 1979
-
(1979)
Biochem Pharmacol
, vol.28
, pp. 2993-2997
-
-
Sirotnak, F.M.1
Chello, P.L.2
Moccio, D.M.3
-
15
-
-
0024379691
-
Lack of interference by the unnatural isomer of 5-formyltetrahydrofolate with the effects of the natural isomer in leucovorin preparations
-
Jolivet J, Bertrand R: Lack of interference by the unnatural isomer of 5-formyltetrahydrofolate with the effects of the natural isomer in leucovorin preparations. J Natl Cancer Inst 81:1175-1178, 1989
-
(1989)
J Natl Cancer Inst
, vol.81
, pp. 1175-1178
-
-
Jolivet, J.1
Bertrand, R.2
-
16
-
-
0021268738
-
Pharmacokinetics of the diastereo isomers of leucovorin after intravenous and oral administration in normal subjects
-
Straw JA, Szapary D, Wynn WT: Pharmacokinetics of the diastereo isomers of leucovorin after intravenous and oral administration in normal subjects. Cancer Res 44:3114-3119, 1984
-
(1984)
Cancer Res
, vol.44
, pp. 3114-3119
-
-
Straw, J.A.1
Szapary, D.2
Wynn, W.T.3
-
17
-
-
0023945440
-
Direct resolution of the stereo isomers of leucovorin and 5-methyltetrahydrofolate using a bovine serum albumen high performance liquid chromotographic chiral stationary phase coupled to a achiral phenyl column
-
Wainer IM, Stiffin RM: Direct resolution of the stereo isomers of leucovorin and 5-methyltetrahydrofolate using a bovine serum albumen high performance liquid chromotographic chiral stationary phase coupled to a achiral phenyl column. J Chromotogr 424:158-162, 1988
-
(1988)
J Chromotogr
, vol.424
, pp. 158-162
-
-
Wainer, I.M.1
Stiffin, R.M.2
-
18
-
-
0018264544
-
Lack of stereospecificity at carbon 6 of methyltetrahydrofolate transport in Erlich ascites tumor cells: Carrier mediated transport of both stereoisomers
-
White JC, Bailey BD, Goldman ID: Lack of stereospecificity at carbon 6 of methyltetrahydrofolate transport in Erlich ascites tumor cells: Carrier mediated transport of both stereoisomers. J Biol Chem 253:242-245, 1978
-
(1978)
J Biol Chem
, vol.253
, pp. 242-245
-
-
White, J.C.1
Bailey, B.D.2
Goldman, I.D.3
-
19
-
-
0024227911
-
Selectivity of CF and 5-fluorouracil: Critical role of polyglutamylation
-
Houghton JA, Williams LG, DeGraff SS, et al: Selectivity of CF and 5-fluorouracil: Critical role of polyglutamylation. Adv Exp Med Biol 244:85-95, 1988
-
(1988)
Adv Exp Med Biol
, vol.244
, pp. 85-95
-
-
Houghton, J.A.1
Williams, L.G.2
Degraff, S.S.3
-
20
-
-
0025981649
-
Role of polyglutamates in biochemical modulation of fluoropyrimidines by leucovorin
-
Romanin IA, Lin JT, Niedzwieck ID, et al: Role of polyglutamates in biochemical modulation of fluoropyrimidines by leucovorin. Cancer Res 51:789-793, 1991
-
(1991)
Cancer Res
, vol.51
, pp. 789-793
-
-
Romanin, I.A.1
Lin, J.T.2
Niedzwieck, I.D.3
-
21
-
-
0023481795
-
Absorption kinetics of orally administered leucovorin calcium
-
McGuire BW, Sai LL, Haynes JD, et al: Absorption kinetics of orally administered leucovorin calcium. NCI Monogr 5:47-56, 1987
-
(1987)
NCI Monogr
, vol.5
, pp. 47-56
-
-
McGuire, B.W.1
Sai, L.L.2
Haynes, J.D.3
-
22
-
-
0024578676
-
Effect of polyglutamation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2′-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft
-
Radvadpa RS, Houghton PJ, Houghton JA: Effect of polyglutamation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2′-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft. Biochem Pharmacol 38:335-342, 1989
-
(1989)
Biochem Pharmacol
, vol.38
, pp. 335-342
-
-
Radvadpa, R.S.1
Houghton, P.J.2
Houghton, J.A.3
-
23
-
-
0024560571
-
Clinical pharmacology of the stereo isomers of leucovorin during repeated oral dosing
-
Schilsky RL, Choi KE, Vokes EE, et al: Clinical pharmacology of the stereo isomers of leucovorin during repeated oral dosing. Cancer 63:1018-1021, 1989
-
(1989)
Cancer
, vol.63
, pp. 1018-1021
-
-
Schilsky, R.L.1
Choi, K.E.2
Vokes, E.E.3
-
24
-
-
0022624346
-
Treatment of advanced colorectal and gastric carcinomas with 5-FU and high dose folinic acid
-
Machover D, Goldschmidt E, Chollet P, et al: Treatment of advanced colorectal and gastric carcinomas with 5-FU and high dose folinic acid. J Clin Oncol 4:685-696, 1986
-
(1986)
J Clin Oncol
, vol.4
, pp. 685-696
-
-
Machover, D.1
Goldschmidt, E.2
Chollet, P.3
-
25
-
-
0016799829
-
Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial
-
Pocock SJ, Simon R: Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometric 31:103-115, 1975
-
(1975)
Biometric
, vol.31
, pp. 103-115
-
-
Pocock, S.J.1
Simon, R.2
-
26
-
-
0026086871
-
Inhibition of fluorouracil-induced stomatitis by oral cryotherapy
-
Mahood DJ, Dose AM, Loprinzi CL, et al: Inhibition of fluorouracil-induced stomatitis by oral cryotherapy. J Clin Oncol 9:449-452, 1991
-
(1991)
J Clin Oncol
, vol.9
, pp. 449-452
-
-
Mahood, D.J.1
Dose, A.M.2
Loprinzi, C.L.3
-
27
-
-
0000336139
-
Regression models and life-tables
-
Cox DR: Regression models and life-tables. J R Stat Soc (B) 34:187-220, 1972
-
(1972)
J R Stat Soc (B)
, vol.34
, pp. 187-220
-
-
Cox, D.R.1
-
28
-
-
0004239503
-
-
Pacific Grove, CA, Wadsworth & Brooks/Cole
-
Becker R, Chambers J, Wilks A: The New S Language. Pacific Grove, CA, Wadsworth & Brooks/Cole, 1988
-
(1988)
The New s Language
-
-
Becker, R.1
Chambers, J.2
Wilks, A.3
-
29
-
-
33845382806
-
Nonparametric estimation from incomplete observations
-
Kaplan EL, Meir P: Nonparametric estimation from incomplete observations. J Am Stat Assoc 53:457-481, 1958
-
(1958)
J Am Stat Assoc
, vol.53
, pp. 457-481
-
-
Kaplan, E.L.1
Meir, P.2
-
30
-
-
84959801619
-
Statistical Aspects of the analysis of data from retrospective studies of disease
-
Mantel N, Haenszel W: Statistical Aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 22:719-748, 1959
-
(1959)
J Natl Cancer Inst
, vol.22
, pp. 719-748
-
-
Mantel, N.1
Haenszel, W.2
-
31
-
-
0028175144
-
Randomized comparison of two schedules of fluorouracil and leucovorin in the treatment of advanced colorectal cancer
-
Buroker TR, O'Connell MJ, Wieand HS, et al: Randomized comparison of two schedules of fluorouracil and leucovorin in the treatment of advanced colorectal cancer. J Clin Oncol 12:14-20, 1994
-
(1994)
J Clin Oncol
, vol.12
, pp. 14-20
-
-
Buroker, T.R.1
O'Connell, M.J.2
Wieand, H.S.3
-
32
-
-
0024347268
-
Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in advanced colorectal carcinoma
-
Poon MA, O'Connell MJ, Moertel CG, et al: Biochemical modulation of fluorouracil: Evidence of significant improvement of survival and quality of life in advanced colorectal carcinoma. J Clin Oncol 7:1407-1418, 1989
-
(1989)
J Clin Oncol
, vol.7
, pp. 1407-1418
-
-
Poon, M.A.1
O'Connell, M.J.2
Moertel, C.G.3
-
33
-
-
0021268738
-
Unavailability of high dose oral leucovorin after intravenous and oral administration to normal subjects
-
Hines JD, Zakem MH, Adelstein DJ, et al: Unavailability of high dose oral leucovorin after intravenous and oral administration to normal subjects. Cancer Res 44:3114-3119, 1984
-
(1984)
Cancer Res
, vol.44
, pp. 3114-3119
-
-
Hines, J.D.1
Zakem, M.H.2
Adelstein, D.J.3
-
34
-
-
0024550278
-
Efficacy of high dose oral leucovorin and 5-fluorouracil in advanced colorectal carcinoma: Plasma and tissue pharmacokinetics
-
Hines JD, Adelstein DJ, Spiess JL, et al: Efficacy of high dose oral leucovorin and 5-fluorouracil in advanced colorectal carcinoma: Plasma and tissue pharmacokinetics. Cancer 63:1022-1025, 1989
-
(1989)
Cancer
, vol.63
, pp. 1022-1025
-
-
Hines, J.D.1
Adelstein, D.J.2
Spiess, J.L.3
-
35
-
-
0027848868
-
5-Fluorouracil combined with the pure [6S]-stereoisomer of folinic acid in high doses for the treatment of patients with advanced colorectal carcinoma: A phase I-II study of two consecutive regimens
-
Machover D, Grison X, Goldschmidt E, et al: 5-Fluorouracil combined with the pure [6S]-stereoisomer of folinic acid in high doses for the treatment of patients with advanced colorectal carcinoma: A phase I-II study of two consecutive regimens. Adv Exp Med Biol 339:81-98, 1993
-
(1993)
Adv Exp Med Biol
, vol.339
, pp. 81-98
-
-
Machover, D.1
Grison, X.2
Goldschmidt, E.3
-
36
-
-
0028827433
-
A phase II and pharmacokinetic study of 6S-leucovorin plus 5-fluorouracil in patients with colorectal carcinoma
-
Meropol N, Petrelli NJ, Rustum YM, et al: A phase II and pharmacokinetic study of 6S-leucovorin plus 5-fluorouracil in patients with colorectal carcinoma. Invest New Drugs 13:149-155, 1995
-
(1995)
Invest New Drugs
, vol.13
, pp. 149-155
-
-
Meropol, N.1
Petrelli, N.J.2
Rustum, Y.M.3
-
37
-
-
0343469030
-
Serum and tissue levels of 1-folinic acid acid (fa) after iv bolus of either racemic (d,1) or pure 1-enantiomer(1-fa)
-
abstr
-
Schuller J, Czejka M, Pietrzak C, et al: Serum and tissue levels of 1-folinic acid acid (fa) after iv bolus of either racemic (d,1) or pure 1-enantiomer(1-fa). Proc Am Soc Clin Oncol 15:175, 1996 (abstr)
-
(1996)
Proc Am Soc Clin Oncol
, vol.15
, pp. 175
-
-
Schuller, J.1
Czejka, M.2
Pietrzak, C.3
-
38
-
-
0030048024
-
A phase II trial of 5-fluorouracil and 1-leucovorin in patients with metastatic colorectal cancer
-
Erlichman C, Fine S, Kerr I, et al: A phase II trial of 5-fluorouracil and 1-leucovorin in patients with metastatic colorectal cancer. Am J Clin Oncol 19:26-31, 1996
-
(1996)
Am J Clin Oncol
, vol.19
, pp. 26-31
-
-
Erlichman, C.1
Fine, S.2
Kerr, I.3
-
39
-
-
0029059136
-
A phase II trial of 1-leucovorin and 5-fluorouracil in advanced colorectal cancer: 1-leucovorin and 5-fu study group
-
Konoshi K, Yabushita K, Taguchi T, et al: A phase II trial of 1-leucovorin and 5-fluorouracil in advanced colorectal cancer: 1-leucovorin and 5-fu study group. Jpn J Cancer Chemother 22:925-932, 1995
-
(1995)
Jpn J Cancer Chemother
, vol.22
, pp. 925-932
-
-
Konoshi, K.1
Yabushita, K.2
Taguchi, T.3
-
40
-
-
0031059138
-
Fluorouracil plus racemic leucovorin versus fluorouracil combined with the pure 1-isomer of leucovorin for the treatment of advanced colorectal cancer: A randomized phase III study
-
Scheithauer W, Kornek G, Marczell A, et al: Fluorouracil plus racemic leucovorin versus fluorouracil combined with the pure 1-isomer of leucovorin for the treatment of advanced colorectal cancer: A randomized phase III study. J Clin Oncol 15:908-914, 1997
-
(1997)
J Clin Oncol
, vol.15
, pp. 908-914
-
-
Scheithauer, W.1
Kornek, G.2
Marczell, A.3
|