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Volumn 19, Issue 1, 1996, Pages 26-31

A phase II trial of 5-fluorouracil and 1-leucovorin in patients with metastatic colorectal cancer

Author keywords

5FU; Colorectal metastasis Phase II; Leucovorin

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

EID: 0030048024     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-199602000-00006     Document Type: Article
Times cited : (10)

References (17)
  • 1
    • 0023874456 scopus 로고
    • A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma
    • Erlichman C, Fine S, Wong A, Elhakim T. A randomized trial of fluorouracil and folinic acid in patients with metastatic colorectal carcinoma. J Clin Oncol 1988;6:469-75.
    • (1988) J Clin Oncol , vol.6 , pp. 469-475
    • Erlichman, C.1    Fine, S.2    Wong, A.3    Elhakim, T.4
  • 2
    • 0026006962 scopus 로고
    • Biochemical modulation of fluorouracil with leucovorin: Confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer
    • Poon MA, O'Connell MJ, Wieand HS, et al. Biochemical modulation of fluorouracil with leucovorin: confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer. J Clin Oncol 1991;9:1967-72.
    • (1991) J Clin Oncol , vol.9 , pp. 1967-1972
    • Poon, M.A.1    O'Connell, M.J.2    Wieand, H.S.3
  • 3
    • 0026721532 scopus 로고
    • Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: Evidence in terms of response rate
    • The Advanced Colorectal Cancer Meta-Analysis Project. Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. J Clin Oncol 1992;10:896-90.
    • (1992) J Clin Oncol , vol.10 , pp. 896-990
  • 4
    • 0020660706 scopus 로고
    • Relationship of cellular folate cofactor pools to the activity of 5-fluorouracil
    • Yin M-B, Zakrzewski SF, Hakala MT. Relationship of cellular folate cofactor pools to the activity of 5-fluorouracil. Mol Pharmacol 1983;23:190-7.
    • (1983) Mol Pharmacol , vol.23 , pp. 190-197
    • Yin, M.-B.1    Zakrzewski, S.F.2    Hakala, M.T.3
  • 5
    • 0022479537 scopus 로고
    • Folinic acid augmentation of the effects of fluoropyrimidines on murine and human leukemic cells
    • Keyomarsi K, Moran RG. Folinic acid augmentation of the effects of fluoropyrimidines on murine and human leukemic cells. Cancer Res 1986;16:5229-35.
    • (1986) Cancer Res , vol.16 , pp. 5229-5235
    • Keyomarsi, K.1    Moran, R.G.2
  • 6
    • 0025277045 scopus 로고
    • Influence of dose of [6RS] leucovorin on reduced folate pools and 5-fluorouracil-mediated thymidylate synthase inhibition in human colon adenocarcinoma xenografts
    • Houghton JA, Williams LG, Cheshire PJ, Wainer IW, Jadaud P, Houghton PJ. Influence of dose of [6RS] leucovorin on reduced folate pools and 5-fluorouracil-mediated thymidylate synthase inhibition in human colon adenocarcinoma xenografts. Cancer Res 1990;50:3940-6.
    • (1990) Cancer Res , vol.50 , pp. 3940-3946
    • Houghton, J.A.1    Williams, L.G.2    Cheshire, P.J.3    Wainer, I.W.4    Jadaud, P.5    Houghton, P.J.6
  • 7
    • 0018690601 scopus 로고
    • Stereospecificity at carbon 6 of formyltetrahydrofolate as a competitive inhibitor of transport and cytotoxicity of methotrexate in vitro
    • Sirotnak FM, Chello PL, Moccio DM, et al. Stereospecificity at carbon 6 of formyltetrahydrofolate as a competitive inhibitor of transport and cytotoxicity of methotrexate in vitro. Biochem Pharmacol 1979;28:2993-7.
    • (1979) Biochem Pharmacol , vol.28 , pp. 2993-2997
    • Sirotnak, F.M.1    Chello, P.L.2    Moccio, D.M.3
  • 8
    • 0024379691 scopus 로고
    • Lack of interference by the unnatural isomer of 5-formyltetrahydrofolate with the effects of the natural isomer in leucovorin preparations
    • Bertrand R, Jolivet J. Lack of interference by the unnatural isomer of 5-formyltetrahydrofolate with the effects of the natural isomer in leucovorin preparations. J Natl Cancer Inst 1989;81:1175-8.
    • (1989) J Natl Cancer Inst , vol.81 , pp. 1175-1178
    • Bertrand, R.1    Jolivet, J.2
  • 9
  • 10
    • 33845382806 scopus 로고
    • Non-parametric estimation from incomplete observations
    • Kaplan EL, Meier P. Non-parametric estimation from incomplete observations. J Am Stat Soc 1958;53:457-81.
    • (1958) J Am Stat Soc , vol.53 , pp. 457-481
    • Kaplan, E.L.1    Meier, P.2
  • 14
    • 0026507592 scopus 로고
    • Fluorouracil combined with pur (6S)-stereisomer of folinic acid in high doses for treatment of patients with advanced colorectal carcinoma, a phase I-II study
    • Machover D, Grison X, Goldschmidt E, et al. Fluorouracil combined with pur (6S)-stereisomer of folinic acid in high doses for treatment of patients with advanced colorectal carcinoma, a phase I-II study. J Natl Cancer Inst 1992;84:321-7.
    • (1992) J Natl Cancer Inst , vol.84 , pp. 321-327
    • Machover, D.1    Grison, X.2    Goldschmidt, E.3
  • 15
    • 0024560571 scopus 로고
    • Clinical pharmacology of the stereoisomers of leucovorin during oral dosing
    • Schilsky RL, Choi KE, Vokes EE. Clinical pharmacology of the stereoisomers of leucovorin during oral dosing. Cancer 1989;63: 1018-21.
    • (1989) Cancer , vol.63 , pp. 1018-1021
    • Schilsky, R.L.1    Choi, K.E.2    Vokes, E.E.3
  • 16
    • 0027360285 scopus 로고
    • A randomized, double-blind trial of fluorouracil plus placebo versus fluorouracil plus oral leucovorin in patients with metastatic colorectal cancer
    • Laufman LR, Bukowski RM, Collier MA, et al. A randomized, double-blind trial of fluorouracil plus placebo versus fluorouracil plus oral leucovorin in patients with metastatic colorectal cancer. J Clin Oncol 1993;11:1883-93.
    • (1993) J Clin Oncol , vol.11 , pp. 1883-1893
    • Laufman, L.R.1    Bukowski, R.M.2    Collier, M.A.3
  • 17
    • 9044245597 scopus 로고
    • Phase II study of high-dose 5-fluorouracil (FU) with oral leucovorin (LV) in advanced colorectal cancer
    • Blijham GH, Wagener DJ, van Oosterom AT, et al. Phase II study of high-dose 5-fluorouracil (FU) with oral leucovorin (LV) in advanced colorectal cancer. Ann Oncol 1990;1(suppl):45.
    • (1990) Ann Oncol , vol.1 , Issue.SUPPL. , pp. 45
    • Blijham, G.H.1    Wagener, D.J.2    Van Oosterom, A.T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.