-
1
-
-
0014128388
-
Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds
-
HAMMER W, SJOQVIST F. Plasma levels of monomethylated tricyclic antidepressants during treatment with imipramine-like compounds. Life Sci 1967: 6: 1895-1903.
-
(1967)
Life Sci
, vol.6
, pp. 1895-1903
-
-
Hammer, W.1
Sjoqvist, F.2
-
3
-
-
0000165070
-
urinary excretion of nortriptyline and five of its metabolites in man after single and multiple oral doses
-
ALEXANDERSON B, BORGA O urinary excretion of nortriptyline and five of its metabolites in man after single and multiple oral doses. Eur J Clin Pharmacol 1973: 5: 174-180.
-
(1973)
Eur J Clin Pharmacol
, vol.5
, pp. 174-180
-
-
Alexanderson, B.1
Borga, O.2
-
4
-
-
0001140482
-
Stereospecific hydroxyla-tion of nortriptyline in man in relation to interindividual differences in its steady-state plasma level
-
BERTILSSON L, ALEXANDEKSON B. Stereospecific hydroxyla-tion of nortriptyline in man in relation to interindividual differences in its steady-state plasma level. Eur J Clin Pharmacol 1972 4 201-205.
-
(1972)
Eur J Clin Pharmacol
, vol.4
, pp. 201-205
-
-
Bertilsson, L.1
Alexandekson, B.2
-
5
-
-
0022621321
-
Plasma level monitoring of antipsychotic drugs
-
DAHL SG. Plasma level monitoring of antipsychotic drugs. Clin Pharmacokinet 2986: 11: 36-61.
-
(1986)
Clin Pharmacokinet
, vol.11
, pp. 36-61
-
-
Dahl, S.G.1
-
6
-
-
0029979414
-
Polymorphic drug oxidation: relevance to the treatment of psychiatric disorders
-
BERTILSSON L, DAHL ML. Polymorphic drug oxidation: relevance to the treatment of psychiatric disorders. CNS Drugs 1996: 5: 200-223.
-
(1996)
CNS Drugs
, vol.5
, pp. 200-223
-
-
Bertilsson, L.1
Dahl, M.L.2
-
7
-
-
84882991943
-
The molecular gene tics of human drug metabolizing cytochrome P450s. In: PACIFICI GM, FRACCHIA GN, ed. Advances in drug metab olism in man
-
INGELMAN-SUNDBERG M, JOHANSSON I. The molecular gene tics of human drug metabolizing cytochrome P450s. In: PACIFICI GM, FRACCHIA GN, ed. Advances in drug metab olism in man, Luxembourg: European Commission, 1995: 543-585.
-
(1995)
Luxembourg: European Commission
, pp. 543-585
-
-
Ingelman-Sundberg, M.1
Johansson, I.2
-
8
-
-
0017695082
-
Polymorphic hydroxylation of debrisoquine in man
-
MAHGOUB A, IDLE JR, DRING DG et al. Polymorphic hydroxylation of debrisoquine in man. Lancet 1977: 2: 584-586.
-
(1977)
Lancet
, vol.2
, pp. 584-586
-
-
Mahgoub, A.1
Idle, J.R.2
Dring, D.G.3
-
9
-
-
0017667456
-
Polymorphic hydroxylation of debrisoquine in man [letter]
-
TUCKER GT. SILAS JH, IYUN A0 et al. Polymorphic hydroxylation of debrisoquine in man [letter]. Lancet 1977: 2: 718.
-
(1977)
Lancet
, vol.2
, pp. 718
-
-
Tucker, G.T.1
Silas, J.H.2
Iyun, A.O.3
-
10
-
-
0018615011
-
Defective N-oxidation of sparteine in man: a new pharmacogenetic defect
-
EICHELBAUM M, SPANNBRUCKER N, STEINKE B et al. Defective N-oxidation of sparteine in man: a new pharmacogenetic defect. Eur J Clin Pharmacol 1979: 16: 183-187.
-
(1979)
Eur J Clin Pharmacol
, vol.16
, pp. 183-187
-
-
Eichelbaum, M.1
Spannbrucker, N.2
Steinke, B.3
-
11
-
-
0020068049
-
Polymorphic oxidation of sparteine and debrisoquine: related pharma cogenetic entities
-
EICHELBAUM M, BERTILSSON L, SAWE J et al. Polymorphic oxidation of sparteine and debrisoquine: related pharma cogenetic entities. Clin Pharmacol Ther 1982: 31: 184-186.
-
(1982)
Clin Pharmacol Ther
, vol.31
, pp. 184-186
-
-
Eichelbaum, M.1
Bertilsson, L.2
Sawe, J.3
-
12
-
-
0023701452
-
Polymorphic debrisoquine hydroxylation in 757 Swedish subjects
-
STEINER E, BERTILSSON L, SAWE J, BERTLING I, SJOQVIST F. Polymorphic debrisoquine hydroxylation in 757 Swedish subjects. Clin Pharmacol Ther 1988: 44: 431-435.
-
(1988)
Clin Pharmacol Ther
, vol.44
, pp. 431-435
-
-
Steiner, E.1
Bertilsson, L.2
Sawe, J.3
Bertling, I.4
Sjoqvist, F.5
-
13
-
-
0018900001
-
A family and population study of the genetic polymorphism of debriso quine oxidation in a white British population
-
EVANS DA, MAHGOUB A, SLOAN TP et al. A family and population study of the genetic polymorphism of debriso quine oxidation in a white British population. J Med Genet 1980: 17: 102-105.
-
(1980)
J Med Genet
, vol.17
, pp. 102-105
-
-
Evans, D.A.1
Mahgoub, A.2
Sloan, T.P.3
-
14
-
-
0026506140
-
Pronounced differences between native Chinese and Swedish popula tions in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
-
BERTILSSON L, LORI YQ, DU YL et al. Pronounced differences between native Chinese and Swedish popula tions in the polymorphic hydroxylations of debrisoquin and S-mephenytoin. Clin Pharmacol Ther 1992: 51: 388-397.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 388-397
-
-
Bertilsson, L.1
Lori, Y.Q.2
Du, Y.L.3
-
15
-
-
0025950370
-
Debrisoquine/ sparteine hydroxylation genotype and phenotype: ana lysis of common mutations and alleles of CYP2D6 in an European population
-
BROLY F, GAEDIGK A, HEIM M et al. Debrisoquine/ sparteine hydroxylation genotype and phenotype: ana lysis of common mutations and alleles of CYP2D6 in an European population. DNA Cell Biol 1991: 10: 545-558.
-
(1991)
DNA Cell Biol
, vol.10
, pp. 545-558
-
-
Broly, F.1
Gaedigk, A.2
Heim, M.C.3
-
16
-
-
0026610576
-
Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population
-
DAHL M-L, JOHANSSON I, PORSMYR PALMERTZ M et al. Analysis of the CYP2D6 gene in relation to debrisoquine and desipramine hydroxylation in a Swedish population. Clin Pharmacol Ther 1992: 51: 12-17.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 12-17
-
-
Dahl, M.-L.1
Johansson, I.2
Porsmyr Palmertz, M.3
-
17
-
-
0025036544
-
Multiple muta tions of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine
-
KAGIMOTO M, HEIM M, KAGIMOTO K et al. Multiple muta tions of the human cytochrome P450IID6 gene (CYP2D6) in poor metabolizers of debrisoquine. J Biol Chem 1990: 265: 17209-17214.
-
(1990)
J Biol Chem
, vol.265
, pp. 17209-17214
-
-
Kagimoto, M.1
Heim, M.2
Kagimoto, K.3
-
18
-
-
0025080352
-
Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification
-
HEIM M, MEYER UA. Genotyping of poor metabolisers of debrisoquine by allele-specific PCR amplification. Lancet 1990: 336: 529-532.
-
(1990)
Lancet
, vol.336
, pp. 529-532
-
-
Heim, M.1
Meyer, U.A.2
-
19
-
-
0027534276
-
Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine [letter]
-
BERTILSSON L, DAHL M-L, SJOQVIST F et al. Molecular basis for rational megaprescribing in ultrarapid hydroxylators of debrisoquine [letter]. Lancet 1993: 341: 63.
-
(1993)
Lancet
, vol.341
, pp. 63
-
-
Bertilsson, L.1
Dahl, M.-L.2
Sjoqvist, F.3
-
22
-
-
0028942981
-
Prevalence of CYP2D6 gene duplication and its repercus sion on the oxidative phenotype in a white population
-
AGUNDEZ JAG, LEDESMA MC, LADERO JM, BENITEZ J. Prevalence of CYP2D6 gene duplication and its repercus sion on the oxidative phenotype in a white population. Clin Pharmacol Ther 1995: 57: 265-269.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 265-269
-
-
Agundez, J.A.G.1
Ledesma, M.C.2
Ladero, J.M.3
Benitez, J.4
-
23
-
-
0027965620
-
Genetic analysis of the Chinese CYP2D6 locus: characterization of variant CYP2D6 genes present in subjects with diminished capa city for debrisoquine hydroxylation
-
JOHANSSON 1, OSCARSSON M. YUE QY et al. Genetic analysis of the Chinese CYP2D6 locus: characterization of variant CYP2D6 genes present in subjects with diminished capa city for debrisoquine hydroxylation. Mol Pharmacol 1994: 46: 452-459.
-
(1994)
Mol Pharmacol
, vol.46
, pp. 452-459
-
-
Johansson, I.1
Oscarsson, M.2
Yue, Q.Y.3
-
24
-
-
0027527966
-
Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism
-
YOKOTA H. TAMURA S, FLIRUYA H et al. Evidence for a new variant CYP2D6 allele CYP2D6J in a Japanese population associated with lower in vivo rates of sparteine metabolism. Pharmacogenetics 1993: 3: 256-263.
-
Pharmacogenetics
, vol.1993
, pp. 256-263
-
-
Yokota, H.1
Tamura, S.2
Fliruya, H.3
-
25
-
-
0026031652
-
Interethnic variation of drug metabolism
-
KALOW W. Interethnic variation of drug metabolism. Trends Pharmacol Sci 1991: 12: 102-107.
-
(1991)
Trends Pharmacol Sci
, vol.12
, pp. 102-107
-
-
Kalow, W.1
-
26
-
-
0029853664
-
A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity
-
MASIMIREMBWA C, PERSON I, BERTILSSON L, HASLER J, INGELMAN-SUNDBERG M. A novel mutant variant of the CYP2D6 gene (CYP2D6*17) common in a black African population: association with diminished debrisoquine hydroxylase activity. Br J Clin Pharmacol 1996: 42: 713-719.
-
(1996)
Br J Clin Pharmacol
, vol.42
, pp. 713-719
-
-
Masimirembwa, C.1
Person, I.2
Bertilsson, L.3
Hasler, J.4
Ingelman-Sundberg, M.5
-
27
-
-
0030432585
-
Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated func tional CYP2D6 alleles
-
AKLILLU E, PERSON I, BERTILSSON L, JOHANSSON I, RODRIGUEZ F, INGELMAN-SUNDBERG I. Frequent distribution of ultrarapid metabolizers of debrisoquine in an Ethiopian population carrying duplicated and multiduplicated func tional CYP2D6 alleles. J Pharmacol Exp "her 1996: 278: 441-446.
-
(1996)
J Pharmacol Exp "her
, vol.278
, pp. 441-446
-
-
Aklillu, E.1
Person, I.2
Bertilsson, L.3
Johansson, I.4
Rodriguez, F.5
Ingelman-Sundberg, I.6
-
28
-
-
0019199097
-
Nortriptyline and antipyrine clearance in relation to debri soquine hydroxylation in man
-
BERTILSSON L, EICHELBAUM M, MELLSTROM B et al. Nortriptyline and antipyrine clearance in relation to debri soquine hydroxylation in man. Life Sci 1980 27: 1673-1677.
-
(1980)
Life Sci
, vol.27
, pp. 1673-1677
-
-
Bertilsson, L.1
Eichelbaum, M.2
Mellstrom, B.3
-
29
-
-
0019449455
-
E- and Z-10-hydroxylation of nortriptyline; relationship to polymorphic debrisoquine hydroxylation
-
MELLSTROM B, BERTILSSON L, SAWE J et al. E- and Z-10-hydroxylation of nortriptyline; relationship to polymorphic debrisoquine hydroxylation. Clin Pharmacol Ther 1981: 30: 189-193.
-
(1981)
Clin Pharmacol Ther
, vol.30
, pp. 189-193
-
-
Mellstrom, B.1
Bertilsson, L.2
Sawe, J.3
-
30
-
-
0021933958
-
Plasma concentrations of nortriptyline and its 10-hydroxy metabolite in depressed patients - relationship to the debrisoquine metabolic ratio
-
NORDIN C, SIWERS B, BENITEZ J et al. Plasma concentrations of nortriptyline and its 10-hydroxy metabolite in depressed patients - relationship to the debrisoquine metabolic ratio. Br J Clin Pharmacol 1985: 19: 832-835.
-
(1985)
Br J Clin Pharmacol
, vol.19
, pp. 832-835
-
-
Nordin, C.1
Siwers, B.2
Benitez, J.3
-
31
-
-
0020541470
-
E- and Z-10-hydroxylation of nortriptyline by human liver micro-somes - methods and characterization
-
MELLSTROM B, BERTILSSON L, BIRGERSSON C et al. E- and Z-10-hydroxylation of nortriptyline by human liver micro-somes - methods and characterization. Drug Metab Disp 1983: 11: 115-119.
-
(1983)
Drug Metab Disp
, vol.11
, pp. 115-119
-
-
Mellstrom, B.1
Bertilsson, L.2
Birgersson, C.3
-
32
-
-
0019450472
-
Slow hydroxylation of nortriptyline and concomitant poor debri soquine hydroxylation: clinical implication
-
BERTILSSON L, MELLSTROM B, SJOQVIST F et al. Slow hydroxylation of nortriptyline and concomitant poor debri soquine hydroxylation: clinical implication. Lancet 1982: 1: 560-561.
-
(1982)
Lancet
, vol.1
, pp. 560-561
-
-
Bertilsson, L.1
Mellstrom, B.2
Sjoqvist, F.3
-
33
-
-
0021119533
-
Clinical pharmacology of anti-depressant drugs: pharmacogenetics
-
SJOQVIST F, BERTILSSON L. Clinical pharmacology of anti-depressant drugs: pharmacogenetics. In: USDIN E, ASBERG M, BERTILSSON L et al., ed. Frontiers in biochemical and pharmacological research in depression. New York: Raven Press, 1984: 359-372.
-
(1984)
In: USDIN E, ASBERG M, BERTILSSON L et al., ed. Frontiers in biochemical and pharmacological research in depression. New York: Raven Press
, pp. 359-372
-
-
Sjoqvist, F.1
Bertilsson, L.2
-
34
-
-
0022337949
-
Extremely rapid hydroxylation of debrisoquine; a case report with implication for treatment with nortriptyline and other tricyclic antidepressants
-
BERTILSSON L, ABERG-WISTEDT A, GUSTAFSSON LL et al. Extremely rapid hydroxylation of debrisoquine; a case report with implication for treatment with nortriptyline and other tricyclic antidepressants. Ther Drug Monit 1985: 7: 478-480.
-
(1985)
Ther Drug Monit
, vol.7
, pp. 478-480
-
-
Bertilsson, L.1
Aberg-Wistedt, A.2
Gustafsson, L.L.3
-
35
-
-
0020444627
-
Role of oxidation polymorphism on blood and urine concen trations of amitriptyline and its metabolites in man
-
BALANT-GORGIA AE, SCHULTZ P, DAYER P et al. Role of oxidation polymorphism on blood and urine concen trations of amitriptyline and its metabolites in man. Arch Psychiatr Nervenkr 1982: 232: 215-222.
-
(1982)
Arch Psychiatr Nervenkr
, vol.232
, pp. 215-222
-
-
Balant-Gorgia, A.E.1
Schultz, P.2
Dayer, P.3
-
36
-
-
0022481136
-
Amitriptyline metabolism: association with debrisoquine hydroxylation in nonsmokers
-
MELLSTROM B, SAWE J. BERTILSSON L et al. Amitriptyline metabolism: association with debrisoquine hydroxylation in nonsmokers. Clin Pharmacol Ther 1986: 39: 369-371.
-
(1986)
Clin Pharmacol Ther
, vol.39
, pp. 369-371
-
-
Mellstrom, B.1
Sawe, J.2
Bertilsson, L.3
-
37
-
-
0020662811
-
The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine
-
BERTILSSON L, ABERG-WISTEDT A. The debrisoquine hydroxylation test predicts steady-state plasma levels of desipramine. Br J Clin Pharmacol 1983: 1.5: 388-390.
-
(1983)
Br J Clin Pharmacol
, vol.5
, pp. 388-390
-
-
Bertilsson, L.1
ABERG-Wistedt, A.2
-
38
-
-
0021747581
-
Phenotypic consistency in hydroxylation of desmethylimipramine and debrisoquine in healthy subjects and in human liver micro-somes
-
SPINA E, BIRGERSSON C, VON BAHR C et al. Phenotypic consistency in hydroxylation of desmethylimipramine and debrisoquine in healthy subjects and in human liver micro-somes. Clin Pharmacol Ther 1984: 36: 677-682.
-
(1984)
Clin Pharmacol Ther
, vol.36
, pp. 677-682
-
-
Spina, E.1
Birgersson, C.2
VON Bahr, C.3
-
39
-
-
0023139103
-
Hydroxylation of des methylimipramine: dependence on the debrisoquine hydroxy lation phenotype
-
SPINA E, STEINER E, ERICSSON 0 et al. Hydroxylation of des methylimipramine: dependence on the debrisoquine hydroxy lation phenotype. Clin Pharmacol Ther 1987: 41: 314-319.
-
(1987)
Clin Pharmacol Ther
, vol.41
, pp. 314-319
-
-
Spina, E.1
Steiner, E.2
Ericsson, O.3
-
40
-
-
0027167806
-
Polymorphic 2-hydroxylation of desipramine: a population and family study
-
DAHL M-L, ISELIUS L, ALM C et al. Polymorphic 2-hydroxylation of desipramine: a population and family study. Eur J Clin Pharmacol 1993: 44: 445-450.
-
(1993)
Eur J Clin Pharmacol
, vol.44
, pp. 445-450
-
-
Dahl, M.-L.1
Iselius, L.2
Acm, C.3
-
41
-
-
0022898438
-
Impor tance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites
-
BALANT-GORGIA AE, BALANT LP, GENET C et al. Impor tance of oxidative polymorphism and levomepromazine treatment on the steady-state blood concentrations of clomipramine and its major metabolites. Eur J Clin Pharmacol 1986: 31: 449-455.
-
(1986)
Eur J Clin Pharmacol
, vol.31
, pp. 449-455
-
-
Balant-Gorgia, A.E.1
Balant, L.P.2
Genet, C.3
-
42
-
-
0020592679
-
Amitriptyline metabolism; relationship to polymorphic debrisoquine hydroxylation
-
MELLSTROM B, BERTILSSON L, LORI Y-C et al. Amitriptyline metabolism; relationship to polymorphic debrisoquine hydroxylation. Clin Pharmacol Ther 1983: 34: 516-520.
-
(1983)
Clin Pharmacol Ther
, vol.34
, pp. 516-520
-
-
Mellstrom, B.1
Bertilsson, L.2
Lori, Y.-C.3
-
43
-
-
0025964524
-
The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine
-
SKJELBO E, BROSEN K, HALLAS J et al. The mephenytoin oxidation polymorphism is partially responsible for the N-demethylation of imipramine. Clin Pharmacol Ther 1991: 49: 18-23.
-
(1991)
Clin Pharmacol Ther
, vol.49
, pp. 18-23
-
-
Skjelbo, E.1
Brosen, K.2
Hallas, J.3
-
44
-
-
0028059720
-
Involvement of CYP2D6, CYP3A4, and other cytochrome P450 isozymes in N-dealkylation reactions
-
COWRRS RT, SU P, BAKER GB. Involvement of CYP2D6, CYP3A4, and other cytochrome P450 isozymes in N-dealkylation reactions. J Pharmacol Toxicol Methods 1994: 31: 177-186.
-
(1994)
J Pharmacol Toxicol Methods
, vol.31
, pp. 177-186
-
-
Coutss, R.T.1
Baker, G.B.2
Su, P.3
-
45
-
-
0027980392
-
Stereoselective disposition of rnianserin is related to debrisoquine hydroxy lation polymorphism
-
DAHL M-L, TVBRING G, ELWIN C-E et al. Stereoselective disposition of rnianserin is related to debrisoquine hydroxy lation polymorphism. Clin Pharmacol Ther 1994: 56: 176-183.
-
(1994)
Clin Pharmacol Ther
, vol.56
, pp. 176-183
-
-
Dahl, M.-L.1
Tvbring, G.2
Elwin, C.-E.3
-
46
-
-
0028282613
-
Maprotiline metabolism appears to cosegregate with the genetically-determined CYP2D6 polymorphic hydroxylation of debrisoquine
-
FIRKUSNY L, GLEITER H. Maprotiline metabolism appears to cosegregate with the genetically-determined CYP2D6 polymorphic hydroxylation of debrisoquine. Br J Clin Pharmacol 1994: 37: 383-388.
-
(1994)
Br J Clin Pharmacol
, vol.37
, pp. 383-388
-
-
Firkusny, L.1
Gleiter, H.2
-
47
-
-
0029860967
-
Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6, but also CYP1A2 activity
-
CARILLO JA, DAHL M-L, SVENSSON J-0, ALM C, RODRIGUEZ I, BERTILSSON L. Disposition of fluvoxamine in humans is determined by the polymorphic CYP2D6, but also CYP1A2 activity. Clin Pharmacol Ther 1996: 60: 183-190.
-
(1996)
Clin Pharmacol Ther
, vol.60
, pp. 183-190
-
-
Carillo, J.A.1
Dahl, M.-L.2
Svensson, J.O.3
Alm, C.4
Rodriguez, I.5
Bertilsson, L.6
-
48
-
-
0026606822
-
The relationship between paroxetine and the sparteine oxidation poly morphism
-
SINDRUP SH, BROSEN K, GRAM LF et al. The relationship between paroxetine and the sparteine oxidation poly morphism. Clin Pharmacol Ther 1992: 51: 278-287.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 278-287
-
-
Sindrup, S.H.1
Brosen, K.2
Gram, L.F.3
-
49
-
-
0027472058
-
Pharmaco-kinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms
-
SINDRUP SH, BROSEN K, HANSEN MGJ et al. Pharmaco-kinetics of citalopram in relation to the sparteine and the mephenytoin oxidation polymorphisms. Ther Drug Monit 1993: 15: 11-17.
-
(1993)
Ther Drug Monit
, vol.15
, pp. 11-17
-
-
Sindrup, S.H.1
Brosen, K.2
Hansen, M.G.J.3
-
50
-
-
0023864115
-
Pharmacokinetic and pharmacodynamic consequences of stereoselective drug metabolism in man
-
EICHELBA~JM M. Pharmacokinetic and pharmacodynamic consequences of stereoselective drug metabolism in man. Biochem Pharmacol 1988: 37: 93-96.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 93-96
-
-
Eichelba, M.1
-
51
-
-
0029953756
-
Mirtazapine A review of its pharma cology and therapeutic potential in the management of major depression
-
DAVIS R, WILDE MI. Mirtazapine. A review of its pharma cology and therapeutic potential in the management of major depression. CNS Drugs 1996: 5: 389-402.
-
(1996)
CNS Drugs
, vol.5
, pp. 389-402
-
-
Davis, R.1
Wilde, M.I.2
-
52
-
-
0031029475
-
In vitro and in vivo studies on the disposition of mirtazapine in humans
-
DAHL M-L, VOORTMAN G, ALM C et al. In vitro and in vivo studies on the disposition of mirtazapine in humans. Clin Drug Invest 1997: 13: 37-46.
-
(1997)
Clin Drug Invest
, vol.13
, pp. 37-46
-
-
Dahl, M.L.1
Voortman, G.2
Alm, C.3
-
53
-
-
0026606822
-
The relationship between paroxetine and the sparteine oxidation poly morphism
-
SINDRUP SH, BROSEN K, GRAM LF et al. The relationship between paroxetine and the sparteine oxidation poly morphism. Clin Pharmacol Ther 1992: 51: 278-287.
-
(1992)
Clin Pharmacol Ther
, vol.51
, pp. 278-287
-
-
Sindrup, S.H.1
Brosen, K.2
Gram, L.F.3
-
55
-
-
0028318482
-
Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: evidence from a thera peutic drug monitoring service
-
JERLING M, LINDSTROM L, BONDESSON U, BERTILSSON L. Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: evidence from a thera peutic drug monitoring service. Ther Drug Monit 1994: 16: 368-374.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 368-374
-
-
Jerling, M.1
Lindstrom, L.2
Bondesson, U.3
Bertilsson, L.4
-
56
-
-
0027985726
-
Clozapine disposition covaries with CYPlA2 activity determined by a caffeine test
-
BERTILSSON L, CARRILLO JA, DAHL M-L et al. Clozapine disposition covaries with CYPlA2 activity determined by a caffeine test. Br J Clin Pharmacol 1994: 38: 471-473.
-
(1994)
Br J Clin Pharmacol
, vol.38
, pp. 471-473
-
-
Bertilsson, L.1
Carrillo, J.A.2
Dahl, M.L.3
-
57
-
-
0027406654
-
Fluvoxamine is a potent inhibitor of cytochrome P4501A2
-
BR0SEN K, SKJELBO E, RASM~JSSEN BB, POULSEN HE, LOFT S. Fluvoxamine is a potent inhibitor of cytochrome P4501A2. Biochem Pharmacol 1993: 45: 1211-1214.
-
(1993)
Biochem Pharmacol
, vol.45
, pp. 1211-1214
-
-
Brosen, K.1
Skjelbo, E.2
Rasmussen, B.B.3
Poulsen, H.E.4
Loft, S.5
-
58
-
-
0027383271
-
The pharmacogenetics of the selective serotonin reuptake inhibitors
-
BKGSEN K. The pharmacogenetics of the selective serotonin reuptake inhibitors. Clin Invest 1993: 71: 1002-1009.
-
(1993)
Clin Invest
, vol.71
, pp. 1002-1009
-
-
Bkgsen, K.1
-
59
-
-
0029016328
-
Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19
-
GRAM LF, GUENTERR TW, GRANGE s et a\. Moclobemide, a substrate of CYP2C19 and an inhibitor of CYP2C19, CYP2D6 and CYPlA2; a panel study. Clin Pharmacol Ther 1995: 57: 670-677.
-
(1995)
CYP2D6 and CYPlA2; a panel study. Clin Pharmacol Ther
, vol.57
, pp. 670-677
-
-
Gram, L.F.1
Guenterr, T.W.2
Grange, S.3
-
60
-
-
84882987714
-
Inhibition by venlafaxine (VF) and other SHT uptake inhibitors of the polymorphic enzyme CYP2D6 [abstract]
-
22nd Annual Meeting of the American College of Neuropsychopharma-cologyDecember
-
SELLERS EM, BALL SE, CHELJNG SW et al. Inhibition by venlafaxine (VF) and other SHT uptake inhibitors of the polymorphic enzyme CYP2D6 [abstract]. 22nd Annual Meeting of the American College of Neuropsychopharma-cology, 13-17 December 1993, Honolulu, 163.
-
(1993)
Honolulu
, vol.163
, pp. 13-17
-
-
Sellers, E.M.1
Ball, S.E.2
Cheljng, S.W.3
-
61
-
-
0026787192
-
The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes
-
CREWE HR, LENNARD MS, TUCKER GT et al. The effect of selective serotonin re-uptake inhibitors on cytochrome P4502D6 (CYP2D6) activity in human liver microsomes. Br J Clin Pharmacol 1992: 34: 262-265.
-
(1992)
Br J Clin Pharmacol
, vol.34
, pp. 262-265
-
-
Crewe, H.R.1
Lennard, M.S.2
Tucker, G.T.3
-
63
-
-
0028115901
-
The use of thera peutic drug monitoring data to document kinetic drug interactions: an example with amitriptyline and nortripty-line
-
JERLING M, BERTILSSON L, SJOUVIST F. The use of thera peutic drug monitoring data to document kinetic drug interactions: an example with amitriptyline and nortripty-line. Ther Drug Monit 1994: 16: 1-12.
-
(1994)
Ther Drug Monit
, vol.16
, pp. 1-12
-
-
Jerling, M.1
Bertilsson, L.2
Sjouvist, F.3
|