Activity relationships of cyclic enediynes related to dynemicin A-I. Synthesis and antitumor activity of 9-acetoxy enediynes equipped with aryl carbamate moieties

Bioorganic and Medicinal Chemistry

Volumn 5, Issue 5, 1997, Pages 883-901

  Unno, Ryoichi ^a   Michishita, Hisashi ^a   Inagaki, Hideaki ^a   Suzuki, Yoko ^a   Baba, Yutaka ^a   Jomori, Takahito ^a   Nishikawa, Toshio ^b   Isobe, Minoru ^b  

^a SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; DYNEMICIN A; ANTHRAQUINONE DERIVATIVE; DNA; ENEDIYNE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER; CYTOTOXICITY; DRUG ACTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA P 388; MOUSE; NONHUMAN; SARCOMA; SQUAMOUS CELL CARCINOMA; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL DEATH; CELL LINE; CHEMISTRY; DRUG DESIGN; DRUG EFFECT; DRUG SCREENING; STEREOISOMERISM; SYNTHESIS;

ANIMALS; ANTHRAQUINONES; ANTIBIOTICS, ANTINEOPLASTIC; CELL DEATH; CELL LINE; DNA; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; ENEDIYNES; HUMANS; LEUKEMIA P388; MICE; SARCOMA, EXPERIMENTAL; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0030612528     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(97)00026-6     Document Type: Article

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