Synthesis and biological evaluation of novel cyclic enediyne compounds related to dynemicin A as antitumor agents

Chemical and Pharmaceutical Bulletin

Volumn 45, Issue 1, 1997, Pages 125-133

  Unno, Ryoichi ^a   Michishita, Hisashi ^a   Inagaki, Hideaki ^a   Baba, Yutaka ^a   Jomori, Takahito ^a   Nishikawa, Toshio ^b   Isobe, Minoru ^b  

^a SANWA KAGAKU KENKYUSHO CO LTD   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

Author keywords

antitumor activity; bicyclo 7,3,1 tridee 4 ene 2,6 diyne; cyclic enediyne; cytotoxicity; DNA cleavage

Indexed keywords

ANTINEOPLASTIC AGENT; DYNEMICIN A; DYNEMICIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CYTOTOXICITY; DNA CLEAVAGE; DRUG POTENCY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA; LUNG CARCINOMA;

EID: 0031030379     PISSN: 00092363     EISSN: None     Source Type: Journal    
DOI: 10.1248/cpb.45.125     Document Type: Article

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