α(1D)-Adrenergic receptors and mitogen-activated protein kinase mediate increased protein synthesis by arterial smooth muscle

Molecular Pharmacology

Volumn 51, Issue 5, 1997, Pages 764-775

  Xin, Xiaohua ^a   Yang, Nengyu ^a   Eckhart, Andrea D ^a   Faber, James E ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 8 [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] 8 AZASPIRO[4.5]DECANE 7,9 DIONE; ALPHA 1 ADRENERGIC RECEPTOR; CHLOROETHYLCLONIDINE; MITOGEN ACTIVATED PROTEIN KINASE; ADRENERGIC RECEPTOR ALPHA(1D); MESSENGER RNA; MUSCLE PROTEIN; NORADRENALIN; ONCOPROTEIN; PIPERAZINE DERIVATIVE; PROTEIN C FOS; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN SERINE THREONINE KINASE; RAF PROTEIN; TYROSINE;

ANIMAL CELL; ARTERY MUSCLE; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ENZYME INHIBITION; GROWTH REGULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RAT; ANIMAL; AORTA; BIOSYNTHESIS; CELL CULTURE; CELL DIVISION; CYTOLOGY; DRUG EFFECT; ENZYME ACTIVATION; GENETICS; KINETICS; MALE; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELL DIVISION; CELLS, CULTURED; ENZYME ACTIVATION; KINETICS; MALE; MUSCLE PROTEINS; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; PHOSPHORYLATION; PIPERAZINES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-FOS; PROTO-ONCOGENE PROTEINS C-RAF; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, ALPHA-1; RNA, MESSENGER; TYROSINE;

EID: 0030609866     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.51.5.764     Document Type: Article

References (46)

1. Gibbons, G. H., and V. J. Dzau. Molecular therapies for vascular diseases. Science (Washington D. C.) 272:689-692 (1996).
2. Bevan, R. D. Effect of sympathetic denervation on smooth muscle cell proliferation in the growing rabbit ear artery. Circ. Res. 37:14-19 (1975).
3. Fronek, K., C. M. Bloor, D. Amiel, and M. Chvapil. Effect of long-term sympathectomy on the arterial wall in rabbits and rats. Exp. Mol. Pathol. 28:279-289 (1978).
4. Lee, R. M. K. W., and J. Smeda. Primary versus secondary structural changes of the blood vessels in hypertension. Can. J. Physiol. Pharmacol. 63:392-401 (1985).
5. Majesky, M. W., M. A. Reidy, E. P. Benditt, and M. R. Juchau. Focal smooth muscle cell proliferation in the aortic intima produced by an initiation-promotion sequence. Proc. Natl. Acad. Sci. USA 82:3450-3454 (1985).
6. 2-adrenergic inhibition of DNA synthesis in vascular smooth muscle cells. Mol. Pharmacol. 37:30-36 (1990).
7. 1-adrenoceptor subtypes in vitro and in situ. J. Biol. Chem. 270:30980-30985 (1995).
8. 1-adrenergic receptor subtypes in cultured rabbit aortic vascular smooth muscle cells. J. Cardiovasc. Pharmacol. 27:508-518 (1996).
9. Johnson, M. D., A. Grignolo, C. M. Kuha, and S. M. Schanberg. Hypertension and cardiovascular hypertrophy during chronic catecholamine infusion in rats. Life Sci. 33:169-180 (1983).
10. Kukrega, R. S., B. N. Datta, and R. N. Chakravarti. Catecholamine-induced aggravation of aortic and coronary atherosclerosis. Atherosclerosis 40:292-298 (1981).
11. O'Malley, M. K., E. W. M. McDermott, D. Mehigan, and N. J. O'Higgins. Role of prazosin in reducing the development of rabbit intimai hyperplasia after endothelial denudation. Br. J. Surg. 76:936-938 (1989).
12. 1-adrenergic and other hypertrophic stimulation in cardiac myocytes in culture and in vivo. J. Biol. Chem. 271:5839-5843 (1996).
13. Okazaki, M., Z. W. Hu, M. Fujinaga, and B. B. Hoffman. Alpha 1 adrenergic receptor-induced c-fos gene expression in rat aorta and cultured vascular smooth muscle cells. J. Clin. Invest. 94:210-218 (1994).
14. 1B-adrenergic receptor gene expression by arterial but not venous vascular smooth muscle. Am. J. Physiol. 271:H1599-H1608 (1996).
15. Piascik, M. T., R. D. Guarino, M. S. Smith, E. E. Soltis, D. L. Saussy, and D. M. Perez. The specific contribution of the novel alpha-1D adrenoceptor to the contraction of vascular smooth muscle. J. Pharmacol. Exp. Ther. 275:1583-1589 (1995).
16. 1A subtype. Mol. Pharmacol. 46:823-831 (1994).
17. Yu, S.-M., S.-Y. Tsai, J.-H. Guh, F.-N. Ko, C.-M. Teng, and J. T. Ou. Mechanism of catecholamine-induced proliferation of vascular smooth muscle cells. Circulation 94:547-554 (1996).
18. Post, G. R., and J. H. Brown. G protein-coupled receptors and signaling pathways regulating growth responses. FASEB J. 10:741-749 (1996).
19. Marshall, C. J. Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation. Cell 80:179-185 (1995).
20. Treisman, R. Regulation of transcription by MAP kinase cascade. Curr. Opin. Cell Biol. 8:205-215 (1996).
21. Glennon, P. E., S. Kaddoura, E. M. Sale, G. J. Sale, S. J. Fuller, and P. H. Sugden. Depletion of mitogen-activated protein kinase using an antisense oligodeoxynucleotide approach downregulates the phenylephrine-induced hypertrophic response in rat cardiac myocytes. Circ. Res. 78:954-961 (1996).
22. 1-adrenoceptors. Hypertension, in press.
23. 1-adrenoceptor subtypes. Naunyn-Schmiedeberg's Arch. Pharmacol. 352: 1-10 (1995).
24. 1-adrenoceptors. Eur. J. Pharmacol. 272:R5-R6 (1995).
25. 1-adrenoceptors in human prostate: implications for adrenoceptor classification. Mol. Pharmacol. 49:209-215 (1996).
26. Karin, M. Signal transduction from the cell surface to the nucleus through the phosphorylation of transcription factors. Curr. Opin. Cell Biol. 6:415-424 (1994).
27. Servant, M. J., E. Giasson, and S. Meloche. Inhibition of growth factor-induced protein synthesis by a selective MEK inhibitor in aortic smooth muscle cells. J. Biol. Chem. 271:16047-16052 (1996).
28. Dudley, D. T., L. Pang, S. J. Decker, A. J. Bridges, and A. R. Saltiel. A synthetic inhibitor of the mitogen-activated protein kinase cascade. Proc. Natl. Acad. Sci. USA 92:7686-7689 (1995).
29. Lomasney, J. W., L. F. Allen, and R. J. Lefkowitz. Molecular Endocrinology: Basic Concepts and Clinical Correlations (B. D. Weintraub, ed.). Raven Press, Ltd., New York, 115-131 (1995).
30. 11 alpha/Gq alpha is accelerated by agonist occupancy of alpha 1A/D, alpha IB, and alpha 1C adrenergic receptors. J. Biol. Chem. 270:17196-17203 (1995).
31. 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy. J. Biol. Chem. 268:15374-15380 (1993).
32. 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy. Proc. Natl. Acad. Sci. USA 91:10109-10113 (1994).
33. 1B-adrenergic receptor mRNA in vascular smooth muscle cells. J. Biol. Chem. 269:1705-1710 (1994).
34. 1-adrenergic receptors in vascular smooth muscle cells. Am. J. Physiol. 268:H1006-H1014 (1995).
35. Schlessinger, J., and A. Ullrich. Growth factor signaling by receptor tyrosine kinases. Neuron 9:393-395 (1992).
36. Molloy, C. J., J. E. Pawlowski, D. S. Taylor, C. E. Turner, H. Weber, M. Peluso, and S. Seiler. Thrombin receptor activation elicits rapid protein tyrosine phosphorylation and stimulation of the Raf-1/MAP kinase pathway preceding delayed mitogenesis in cultured rat aortic smooth muscle cells. J. Clin. Invest. 97:1173-1183 (1996).
37. Tsuda, T., Y. Kawahara, K. Shii, M. Koide, Y. Ishida, and M. Yokoyama. Vasoconstrictor induced protein-tyrosine phosphorylation in cultured vascular smooth muscle cells. FEBS Lett. 285:44-48 (1991).
38. Leduc, I., P. Haddad, E. Giasson, and S. Meloche. Involvement of a tyrosine kinase pathway in the growth-promoting effects of angiotensin II on aortic smooth muscle cells. Mol. Pharmacol. 48:582-592 (1995).
39. Koide, M., Y. Kawahara, T. Tsuda, Y. Ishida, K. Shii, and M. Tokoyama. Stimulation of protein-tyrosine phosphorylation by endothelin-1 in cultured vascular smooth muscle cells. Atherosclerosis 92:1-7 (1992).
40. Macara, I. G., K. M. Lounsbury, S. A. Richards, C. Mckiernan, and B. Bar-Sagi. The Ras superfamily of GTPase. FASEB J. 10:625-630 (1996).
41. 1-Adrenergic stimulation of platelet-derived growth factor A-chain gene expression in rat aorta. J. Biol. Chem. 265:1082-1088 (1990).
42. Cobb, M. H., and E. J. Goldsmith. How MAP kinases are regulated. J. Biol. Chem. 270:14843-14846 (1995).
43. 1 Adrenergic receptors activate phosphatidylinositol 3-kinase in human vascular smooth muscle cells. J. Biol. Chem. 271:8977-8982 (1996).
44. Hawes, B. E., L. M. Luttrell, T. van Biesen, and R. J. Lefkowitz. Phosphatidylinositol 3-kinase is an early intermediate in the Gβγ-mediated mitogen-activated protein kinase signaling pathway. J. Biol. Chem. 271: 12133-12136 (1996).
45. Katoch, S. S., and R. S. Moreland. Agonist and membrane depolarization induced activation of MAP kinase in the swine carotid artery. Am. J. Physiol. 269:H322-H329 (1995).
46. Hollenberg, M. D. Tyrosine kinase pathways and the regulation of smooth muscle contractility. Trends Pharmacol. Sci. 15:108-114 (1994).