Increased levels of 4-hydroxynonenal modified proteins in plasma of children with autoimmune diseases

Free Radical Biology and Medicine

Volumn 23, Issue 3, 1997, Pages 357-360

  Grune, Tilman ^a   Michel, Philip ^a   Sitte, Nicolle ^a   Eggert, Wilfried ^a   Albrecht Nebe, Helga ^a   Esterbauer, Hermann ^b   Siems, Werner G ^c  

^a HUMBOLDT UNIVERSITY   (Germany)

^b UNIVERSITY OF GRAZ   (Austria)

^c Herzog Julius Klinik GmbH & Co KG   (Germany)

Author keywords

4 Hydroxynonenal; Lipid peroxidation; Plasma proteins; Systemic Lupus Erythematosus

Indexed keywords

4 HYDROXYNONENAL; FREE RADICAL; IMMUNOGLOBULIN G; MALONALDEHYDE; PLASMA PROTEIN;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ACTIVITY; ETIOLOGY; HUMAN; IMMUNOBLOTTING; LIPID PEROXIDATION; MOLECULAR WEIGHT; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN MODIFICATION; SYSTEMIC LUPUS ERYTHEMATOSUS;

ADOLESCENT; ALDEHYDES; BLOOD PROTEINS; BLOTTING, WESTERN; CHILD; CHILD, PRESCHOOL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; LIPID PEROXIDATION; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALONDIALDEHYDE;

EID: 0030953727     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(96)00586-2     Document Type: Article

References (24)

1. Esterbauer H., Schauer R. J., Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radic. Biol. Med. 11:1991;81-128.
2. Uchida K., Stadtman E. R. Quantification of 4-hydroxynonenal protein adducts. Methods Enzymol. 233:1994;371-380.
3. Uchida K., Stadtman E. R. Covalent attachment of 4-hydroxynonenal to glyceraldehyde-3-phosphate dehydrogenase. A possible involvement of intra- and intermolecular cross linking reaction. J. Biol. Chem. 268:1993;6388-6393.
4. Uchida K., Toyokuni S., Nishikawa K., Kawakishi S., Oda H., Hiai H., Stadtman E. R. Michael addition-type 4-hydroxy-2-nonenal adducts in modified low-density lipoproteins: Markers for arteriosclerosis. Biochemistry. 33:1994;12487-12494.
5. Esterbauer H., Zollner H. Methods for determination of aldehydic lipid peroxidation products. Free Radic. Biol. Med. 7:1989;197-203.
6. Grune T., Siems W. G., Zollner H., Esterbauer H. Metabolism of 4-hydroxynonenal, a cytotoxic lipid peroxidation product, in Ehrlich mouse ascites cells. Cancer Res. 54:1994;5231-5235.
7. Houglum K., Filip M., Witztum J. L., Chojkier M. Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload. J. Clin. Invest. 86:1990;1991-1998.
8. Palinski W., Ylä-Herttula S., Rosenfeld M. E., Butler S. W., Socher S. A., Witztum J. L. Antisera and monoclonal antibodies specific for epitopes generated during oxidative modification of low density lipoproteins. Arteriosclerosis. 10:1990;325-335.
9. Jiang X., Chen F. The effect of lipid peroxides and superoxide dismutase on SLE: A preliminary study. Clin. Immunol. Immunpathol. 63:1992;39-44.
10. Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 25:1982;1271-1277.
11. Bombardier C., Gladman D. D., Urowitz M. B., Caron D., Chang C. H. Derivation of the SLEDAI: A disease activity index for lupus patients. Arthritis Rheum. 35:1992;630-640.
12. Laemmli U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:1970;680-685.
13. + stimulated lipid peroxidation in rat liver microcosmes. Biochem. J. 208:1982;129-140.
14. Wong S. H. J., Knight J. A., Hopfer S., Zaharia O., Leach C. N., Sunderman F. W. Lipoperoxides in plasma measured by liquid chromatographic separation of malondialdehyde-thiobarbituric acid adduct. Clin. Chem. 33:1987;214-220.
15. Sommerburg O., Grune T., Klee S., Ungemach F. R., Siems W. Formation of 4-hydroxynonenal and further aldehydic mediators of inflammation during bromotrichlorormethane treatment of rat liver cells. Mediat. Inflammat. 2:1993;27-31.
16. Skavril F. V. Immunoglobulin G. Haeberli A. Human protein Data. 1992;VCH Verlagsgesellschaft mbH, Weinheim.
17. Suryaprbha P., Das U. N., Ramesh G., Kumar V., Kumar G. Reactive oxygen species, lipid peroxides and essential fatty acids in patients with rheumatoid arthritis and systemic lupus erythematosus. Prostaglandins Leucot. Essent. Fatty Acids. 187:1992;193-198.
18. Wolff S. P. Diabetis mellitus and free radicals. Brt. Med. Bull. 49:1993;642-652.
19. Lebranchu Y., Malvy D., Richard M. J., Arnaud J., Favier A., Bardos P. Kawasaki disease and oxidative metabolism. Clin. Chim. Acta. 187:1992;193-198.
20. Jiang X., Chen F. The effect of lipid peroxides and superoxide dismutase on systemic lupus erythematosus: A preliminary study. Clin. Immunol. Immunopathol. 63:1992;39-44.
21. Lung C. C., Pinnas J. L., Yahya M. D., Meinke G. C., Mooradian A. D. Malondialdehyde modified proteins and their antibodies in the plasma of control and streptomycin induced diabetic rats. Life Sci. 52:1993;329-337.
22. Amara A., Constans J., Chaugier C., Sebban A. N., Dubourg L., Geffards M. Autoantibodies to malondialdehyde-modified epitope in connective tissue disease and vasculitides. Clin. Exp. Immunol. 101:1996;233-238.
23. Shacter E., Williams J. A., Lim M., Levine R. L. Differential susceptibility of plasma proteins to oxidative modification: Examination by Western blot immunoassay. Free Radic. Biol. Med. 17:1994;429-437.
24. Toyokuni S., Uchida K., Okamaoto K., Hattori-Nakakuki Y., Hiai H., Stadtman E. R. Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with renal carcinogen, ferric nitriloacetate. Proc. Natl. Acad. Sci. USA. 29:1994;2616-2620.