5-HT(1B) receptor antagonist properties of novel arylpiperazide derivatives of 1-naphthylpiperazine

Journal of Medicinal Chemistry

Volumn 40, Issue 24, 1997, Pages 3974-3978

  Jorand Lebrun, Catherine ^a   Pauwels, Petrus J ^a   Palmier, Christiane ^a   Moret, Chantal ^a   Chopin, Philippe ^a   Perez, Michel ^a   Marien, Marc ^a   Halazy, Serge ^a  

^a INSTITUT DE RECHERCHE PIERRE FABRE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 [[8 (4 METHYLPIPERAZIN 1 YL)NAPHTHALEN 2 YL]OXY] 1 (4 O TOLYLPIPERAZIN 1 YL)ETHANONE; 5 CARBAMOYLTRYPTAMINE; CYCLIC AMP; FORSKOLIN; PIPERAZINE DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN 1B AGONIST; SEROTONIN 1B ANTAGONIST; SEROTONIN 1B RECEPTOR; SEROTONIN 1D RECEPTOR; UNCLASSIFIED DRUG; 1 (1 NAPHTHYL)PIPERAZINE; 1-(1-NAPHTHYL)PIPERAZINE; HTR1B PROTEIN, HUMAN; SEROTONIN AGONIST; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; GUINEA PIG; HYPOTHALAMUS; HYPOTHERMIA; INTRAPERITONEAL DRUG ADMINISTRATION; NONHUMAN; ORAL DRUG ADMINISTRATION; SEROTONIN RELEASE; ANIMAL; CELL STRAIN COS1; CHO CELL; DRUG DESIGN; DRUG EFFECT; HAMSTER; HELA CELL; HUMAN; KINETICS; METABOLISM; RAT; SYNTHESIS; ULTRASTRUCTURE;

ANIMALS; CHO CELLS; COS CELLS; CRICETINAE; DRUG DESIGN; GUINEA PIGS; HELA CELLS; HUMANS; KINETICS; PIPERAZINES; RATS; RECEPTOR, SEROTONIN, 5-HT1B; RECEPTORS, SEROTONIN; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS;

EID: 0030608691     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9703552     Document Type: Article

References (25)

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