Inhibition of MAP kinase kinase (MEK) blocks endothelial PGI2 release but has no effect on von willebrand factor secretion or E-selectin expression

FEBS Letters

Volumn 388, Issue 2-3, 1996, Pages 180-184

  Wheeler Jones, Caroline P D ^a   May, Michael J ^a   Houliston, Rebecca A ^a   Pearson, Jeremy D ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Adhesion molecule; Cytokine; Human endothelial cell; MAP kinase; Prostacyclin; Thrombin

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; ENZYME INHIBITOR; INTERLEUKIN 1; MITOGEN ACTIVATED PROTEIN KINASE; PROSTACYCLIN; THROMBIN; TUMOR NECROSIS FACTOR ALPHA; VON WILLEBRAND FACTOR;

ARTICLE; CONTROLLED STUDY; CYTOCHEMISTRY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; UMBILICAL VEIN;

EID: 0030591428     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(96)00547-9     Document Type: Article

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